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MAZDUTIDE

  • Mazdutide

    • GLP1 poly-agonist drug

    Mazdutide (also known as IBI362 or LY3305677) is a dual agonist of the GLP-1 receptor and glucagon receptor. It is an analog of oxyntomodulin (OXM). The

    Mazdutide

    Mazdutide

  • Glucagon-like peptide-1

    • Gastrointestinal peptide hormone involved in glucose homeostasis

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Glucagon-like peptide-1

    Glucagon-like peptide-1

    Glucagon-like_peptide-1

  • Retatrutide

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Retatrutide

    Retatrutide

    Retatrutide

  • Metformin

    • Medication used to treat diabetes

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Metformin

    Metformin

    Metformin

  • Semaglutide

    • Anti-diabetic and anti-obesity medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Semaglutide

    Semaglutide

    Semaglutide

  • Orforglipron

    • Anti-obesity medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Orforglipron

    Orforglipron

    Orforglipron

  • Dapagliflozin

    • Diabetes medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Dapagliflozin

    Dapagliflozin

    Dapagliflozin

  • Innovent Biologics

    • Chinese Biopharmaceutical Company

    due to Food and Drug Administration rejection. In June 2025, Innovent's Mazdutide was approved in China. It was the first Chinese company to win regulatory

    Innovent Biologics

    Innovent Biologics

    Innovent_Biologics

  • Tirzepatide

    • Anti-diabetic and anti-obesity medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Tirzepatide

    Tirzepatide

    Tirzepatide

  • Dipeptidyl peptidase-4 inhibitor

    • Enzyme blocker and diabetes treatment drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Dipeptidyl peptidase-4 inhibitor

    Dipeptidyl peptidase-4 inhibitor

    Dipeptidyl_peptidase-4_inhibitor

  • Empagliflozin

    • Diabetes medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Empagliflozin

    Empagliflozin

  • Insulin icodec/semaglutide

    • Combination drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin icodec/semaglutide

    Insulin_icodec/semaglutide

  • Brenipatide

    • Pharmaceutical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Brenipatide

    Brenipatide

  • Insulin glargine

    • Long-acting insulin

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin glargine

    Insulin glargine

    Insulin_glargine

  • Glucagon-like peptide-1 receptor

    • Receptor activated by peptide hormone GLP-1

    glepaglutide apraglutide maridebart cafraglutide tirzepatide pegapamodutide mazdutide survodutide bamadutide pemvidutide cotadutide retatrutide Lithium chloride

    Glucagon-like peptide-1 receptor

    Glucagon-like peptide-1 receptor

    Glucagon-like_peptide-1_receptor

  • GLP1 poly-agonist peptides

    • Class of drugs used to treat diabetes

    effects have hampered development. The most advanced of these drugs is mazdutide which is in a phase III trial as of 2023. Following the discovery of GLP-1/GIP

    GLP1 poly-agonist peptides

    GLP1_poly-agonist_peptides

  • Sitagliptin/metformin

    • Pharmaceutical drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Sitagliptin/metformin

    Sitagliptin/metformin

  • Sulfonylurea

    • Class of organic compounds used in medicine and agriculture

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Sulfonylurea

    Sulfonylurea

    Sulfonylurea

  • Sitagliptin

    • Diabetes medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Sitagliptin

    Sitagliptin

    Sitagliptin

  • Pioglitazone

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Pioglitazone

    Pioglitazone

    Pioglitazone

  • SGLT2 inhibitor

    • Class of medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    SGLT2 inhibitor

    SGLT2_inhibitor

  • Enavogliflozin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Enavogliflozin

    Enavogliflozin

    Enavogliflozin

  • Diabetes medication

    • Drugs that lower blood glucose levels to treat diabetes

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Diabetes medication

    Diabetes_medication

  • Insulin degludec

    • Ultralong-acting basal insulin analogue

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin degludec

    Insulin degludec

    Insulin_degludec

  • Conveglipron

    • Pharmaceutical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Conveglipron

    Conveglipron

    Conveglipron

  • Liraglutide

    • Anti-diabetic medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Liraglutide

    Liraglutide

    Liraglutide

  • Dulaglutide

    • Diabetes medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Dulaglutide

    Dulaglutide

    Dulaglutide

  • Insulin (medication)

    • Use of insulin protein and analogs as medical treatment

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin (medication)

    Insulin (medication)

    Insulin_(medication)

  • Alpha-glucosidase inhibitor

    • Oral anti-diabetic drugs

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Alpha-glucosidase inhibitor

    Alpha-glucosidase_inhibitor

  • PPAR agonist

    • Drug used for the treatment of symptoms of metabolic syndrome

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    PPAR agonist

    PPAR agonist

    PPAR_agonist

  • Exenatide

    • Medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Exenatide

    Exenatide

    Exenatide

  • Acarbose

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Acarbose

    Acarbose

    Acarbose

  • Saxagliptin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Saxagliptin

    Saxagliptin

    Saxagliptin

  • List of commercially available insulins

    • Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    List of commercially available insulins

    List of commercially available insulins

    List_of_commercially_available_insulins

  • NPH insulin

    • Intermediate acting insulin formulation

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    NPH insulin

    NPH insulin

    NPH_insulin

  • Retagliptin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Retagliptin

    Retagliptin

    Retagliptin

  • CT-868

    • Pharmaceutical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    CT-868

    CT-868

  • Biguanide

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Biguanide

    Biguanide

    Biguanide

  • Linagliptin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Linagliptin

    Linagliptin

    Linagliptin

  • Voglibose

    • Alpha-glucosidase inhibitor

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Voglibose

    Voglibose

    Voglibose

  • Insulin aspart

    • Rapid-acting man-made insulin

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin aspart

    Insulin aspart

    Insulin_aspart

  • Sergliflozin etabonate

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Sergliflozin etabonate

    Sergliflozin etabonate

    Sergliflozin_etabonate

  • Glipizide

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Glipizide

    Glipizide

    Glipizide

  • Fidarestat

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Fidarestat

    Fidarestat

    Fidarestat

  • Insulin icodec

    • Ultralong-acting basal insulin analogue

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin icodec

    Insulin_icodec

  • Glibenclamide

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Glibenclamide

    Glibenclamide

    Glibenclamide

  • Sotagliflozin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Sotagliflozin

    Sotagliflozin

  • Insulin lispro

    • Rapid-acting insuline analog

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin lispro

    Insulin lispro

    Insulin_lispro

  • Donislecel

    • Cellular therapy medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Donislecel

    Donislecel

  • Bexagliflozin

    • Antidiabetic medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Bexagliflozin

    Bexagliflozin

  • Gliclazide

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Gliclazide

    Gliclazide

    Gliclazide

  • Thiazolidinedione

    • Class of chemical compounds

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Thiazolidinedione

    Thiazolidinedione

    Thiazolidinedione

  • Empagliflozin/linagliptin

    • Pharmaceutical drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Empagliflozin/linagliptin

    Empagliflozin/linagliptin

    Empagliflozin/linagliptin

  • ATC code A10

    • Pharmaceutical drug classification

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    ATC code A10

    ATC_code_A10

  • Empagliflozin/metformin

    • Pharmaceutical drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Empagliflozin/metformin

    Empagliflozin/metformin

  • Alogliptin

    • Anti-diabetic drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Alogliptin

    Alogliptin

    Alogliptin

  • Canagliflozin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Canagliflozin

    Canagliflozin

    Canagliflozin

  • Sorbinil

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Sorbinil

    Sorbinil

    Sorbinil

  • Buformin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Buformin

    Buformin

    Buformin

  • Bromocriptine

    • Dopamine agonist medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Bromocriptine

    Bromocriptine

    Bromocriptine

  • Lixisenatide

    • Diabetes drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Lixisenatide

    Lixisenatide

  • Lente insulin

    • Historical formulation of insulin as medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Lente insulin

    Lente insulin

    Lente_insulin

  • Insulin efsitora alfa

    • Medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin efsitora alfa

    Insulin_efsitora_alfa

  • Danuglipron

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Danuglipron

    Danuglipron

    Danuglipron

  • Empagliflozin/linagliptin/metformin

    • Combination drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Empagliflozin/linagliptin/metformin

    Empagliflozin/linagliptin/metformin

  • Insulin degludec/insulin aspart

    • Combination medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin degludec/insulin aspart

    Insulin_degludec/insulin_aspart

  • Troglitazone

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Troglitazone

    Troglitazone

    Troglitazone

  • Insulin glulisine

    • Rapid-acting insulin analogue

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin glulisine

    Insulin glulisine

    Insulin_glulisine

  • Vildagliptin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Vildagliptin

    Vildagliptin

    Vildagliptin

  • Albiglutide

    • Pharmaceutical drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Albiglutide

    Albiglutide

  • Ultralente insulin

    • Long-acting form of insulin

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Ultralente insulin

    Ultralente_insulin

  • Dasiglucagon

    • Medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Dasiglucagon

    Dasiglucagon

  • Repaglinide

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Repaglinide

    Repaglinide

    Repaglinide

  • Rosiglitazone

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Rosiglitazone

    Rosiglitazone

    Rosiglitazone

  • Glimepiride

    • Medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Glimepiride

    Glimepiride

    Glimepiride

  • List of investigational substance-related disorder drugs

    • Investigational substance-related disorder drugs

    STP-7) – metabotropic glutamate mGlu5 receptor antagonist – alcoholism Mazdutide (IBI-362; LY-3305677; OXM-3) – glucagon-like peptide-1 (GLP-1) receptor

    List of investigational substance-related disorder drugs

    List_of_investigational_substance-related_disorder_drugs

  • Lotiglipron

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Lotiglipron

    Lotiglipron

    Lotiglipron

  • Rivoglitazone

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Rivoglitazone

    Rivoglitazone

    Rivoglitazone

  • Saroglitazar

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Saroglitazar

    Saroglitazar

    Saroglitazar

  • Insulin analogue

    • Modified forms of synthetic insulin

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin analogue

    Insulin analogue

    Insulin_analogue

  • Ciglitazone

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Ciglitazone

    Ciglitazone

    Ciglitazone

  • Nateglinide

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Nateglinide

    Nateglinide

    Nateglinide

  • 2023 in science

    • results of health and medical research are reported: phase 2-trialed Mazdutide against type-2 diabetes (9 Nov), phase 1-trialed lepodisiran against cardiovascular

    2023 in science

    2023_in_science

  • Pramlintide

    • Diabetes medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Pramlintide

    Pramlintide

    Pramlintide

  • List of investigational sleep apnea drugs

    • Investigational sleep apnea drugs

    antagonist/anticholinergic) and atomoxetine (norepinephrine reuptake inhibitor) [1], Mazdutide (IBI-362; LY-3305677; OXM-3) – glucagon-like peptide-1 (GLP-1) receptor

    List of investigational sleep apnea drugs

    List_of_investigational_sleep_apnea_drugs

  • Epalrestat

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Epalrestat

    Epalrestat

    Epalrestat

  • Meglitinide

    • Chemical substance

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Meglitinide

    Meglitinide

    Meglitinide

  • Ertugliflozin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Ertugliflozin

    Ertugliflozin

    Ertugliflozin

  • Inhalable insulin

    • Powdered insulin delivered with an inhaler

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Inhalable insulin

    Inhalable insulin

    Inhalable_insulin

  • Gemigliptin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Gemigliptin

    Gemigliptin

    Gemigliptin

  • Dapagliflozin/metformin

    • Two drugs combined to treat diabetes

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Dapagliflozin/metformin

    Dapagliflozin/metformin

  • Sitagliptin/simvastatin

    • Combination drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Sitagliptin/simvastatin

    Sitagliptin/simvastatin

    Sitagliptin/simvastatin

  • Miglitol

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Miglitol

    Miglitol

    Miglitol

  • Insulin degludec/liraglutide

    • Pharmaceutical drug

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin degludec/liraglutide

    Insulin_degludec/liraglutide

  • Regular insulin

    • Short-acting insulin formulation

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Regular insulin

    Regular insulin

    Regular_insulin

  • Velagliflozin

    • Medication

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Velagliflozin

    Velagliflozin

    Velagliflozin

  • Trelagliptin

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Trelagliptin

    Trelagliptin

    Trelagliptin

  • Insulin detemir

    • Long-acting man-made insulin

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Insulin detemir

    Insulin_detemir

  • Lobeglitazone

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Lobeglitazone

    Lobeglitazone

  • Remogliflozin etabonate

    • Chemical compound

    Lixisenatide Orforglipron Semaglutide Taspoglutide† GLP1 poly-agonist peptides Mazdutide (GLP-1/GCGR) Retatrutide§ (GLP-1/GIP/GCGR) Tirzepatide (GLP-1/GIP) DPP-4

    Remogliflozin etabonate

    Remogliflozin etabonate

    Remogliflozin_etabonate

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