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Medication used to treat diabetes
Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes, particularly in
Metformin
Diabetes medication
type 2 diabetes as an adjunct to diet and exercise As monotherapy when metformin is considered inappropriate due to intolerance In addition to other medicinal
Dapagliflozin
Pharmaceutical drug
Sitagliptin/metformin, sold under the brand name Janumet among others, is a fixed-dose combination anti-diabetic medication used to treat type 2 diabetes
Sitagliptin/metformin
Combination drug
Pioglitazone/metformin, sold under the brand name Actoplus Met among others, is a fixed-dose combination anti-diabetic medication used to improve glycemic
Pioglitazone/metformin
Pharmaceutical drug
Empagliflozin/metformin, sold under the brand name Synjardy among others, is a fixed-dose combination anti-diabetic medication used to treat type 2 diabetes
Empagliflozin/metformin
Hormonal disorder in women
help regulate menstrual cycles and reduce acne and excess hair growth. Metformin, a common anti-diabetes drug, increases insulin sensitivity. For fertility
Polyendocrine metabolic ovarian syndrome
Polyendocrine_metabolic_ovarian_syndrome
Two drugs combined to treat diabetes
Dapagliflozin/metformin, sold under the brand name Xigduo Xr among others, is a fixed-dose combination anti-diabetic medication used as an adjunct to
Dapagliflozin/metformin
Pharmaceutical drug
Vildagliptin/metformin, sold under the brand name Eucreas among others, is a fixed-dose combination anti-diabetic medication for the treatment of type
Vildagliptin/metformin
Combination drug
Empagliflozin/linagliptin/metformin, sold under the brand name Trijardy XR, is a fixed-dose combination medication used for the treatment of type 2 diabetes
Empagliflozin/linagliptin/metformin
Empagliflozin/linagliptin/metformin
Form of diabetes mellitus
changes. If blood sugar levels are not adequately lowered, the medication metformin is typically recommended. Many people may eventually also require insulin
Type_2_diabetes
Diabetes medication
nausea and vomiting may occur and seem more pronounced in combination with metformin. Rare but serious adverse events, such as euglycemic diabetic ketoacidosis
Empagliflozin
Diabetes medication
preferred than metformin or a sulfonylurea. It is taken by mouth. It is also available in the fixed-dose combination medication sitagliptin/metformin (Janumet
Sitagliptin
Drugs that lower blood glucose levels to treat diabetes
approved in 2019, consisting of metformin, saxagliptin, and dapagliflozin. Another triple combination approval for metformin, linagliptin, and empagliflozin
Diabetes_medication
Anti-diabetic and anti-obesity medication
type 2 diabetes as an adjunct to diet and exercise as monotherapy when metformin is considered inappropriate due to intolerance or contraindications, in
Semaglutide
Combination drug
Glibenclamide/metformin, also known as glyburide/metformin and sold under the brand name Glucovance, is a fixed-dose combination anti-diabetic medication
Glibenclamide/metformin
Fixed-dose combination anti-diabetic medication
Canagliflozin/metformin, sold under the brand name Vokanamet among others, is a fixed-dose combination anti-diabetic medication used for the treatment
Canagliflozin/metformin
Species of flowering plant in the pea family
blood glucose-lowering activity and the foundation for the discovery of metformin, a treatment for managing symptoms of diabetes mellitus. In ancient herbalism
Galega_officinalis
Anti-diabetic medication
a second-line therapy for diabetes following first-line therapy with metformin. Its effects on long-term health outcomes like heart disease and life
Liraglutide
Medication
diabetes. It is regarded as a second-line option compared to metformin, due to metformin's well-established safety and efficacy. Use of glimepiride is
Glimepiride
Chemical compound
not controlled by diet and exercise alone. It is not as good as either metformin or insulin in those who have gestational diabetes. Frequently reported
Glibenclamide
Anti-diabetic drug
commonly used in combination with metformin in people whose diabetes cannot adequately be controlled with metformin alone. In April 2016, the U.S. Food
Alogliptin
Anti-obesity medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Orforglipron
Class of medication
line pharmacological therapy for type 2 diabetes (usually together with metformin), specifically in patients with chronic kidney disease, cardiovascular
SGLT2_inhibitor
Chemical compound
Agency has also approved a combination of vildagliptin and metformin, vildagliptin/metformin (Eucreas by Novartis) as an oral treatment for type-2 diabetes
Vildagliptin
Medication
potentially other antidiabetic medication. It is a treatment option after metformin and sulfonylureas. It is given by injection under the skin. Common side
Exenatide
GLP1 poly-agonist drug
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Mazdutide
Class of organic compounds used in medicine and agriculture
limited evidence if the combined use of Metformin with Sulphonylurea compared to the combination of Metformin plus another glucose-lowering intervention
Sulfonylurea
Series of interconnected biochemical reactions
glycerol from lipolysis. The drug metformin can cause lactic acidosis in patients with kidney failure because metformin inhibits the hepatic gluconeogenesis
Cori_cycle
Chemical compound
used for diabetes mellitus or prediabetes treatment. Examples include: Metformin - widely used in treatment of diabetes mellitus type 2 Phenformin - withdrawn
Biguanide
Pharmaceutical drug classification
Metformin and alogliptin A10BD14 Metformin and repaglinide A10BD15 Metformin and dapagliflozin A10BD16 Metformin and canagliflozin A10BD17 Metformin and
ATC_code_A10
Long-acting insulin
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_glargine
Diabetes medication
in combination with other medicines for type 2 diabetes, in particular metformin, sulfonylureas, thiazolidinediones, and insulin taken concomitantly with
Dulaglutide
Pharmaceutical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Brenipatide
Anti-diabetic and anti-obesity medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Tirzepatide
Chemical compound
anti-diabetic medication used to treat type 2 diabetes. It may be used with metformin, a sulfonylurea, or insulin. Use is recommended together with exercise
Pioglitazone
Enzyme blocker and diabetes treatment drug
Cochrane systematic review found insufficient evidence to suggest that metformin monotherapy reduced all-cause mortality, serious adverse events, cardiovascular
Dipeptidyl peptidase-4 inhibitor
Dipeptidyl_peptidase-4_inhibitor
Class of drugs used to treat diabetes
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
GLP1_poly-agonist_peptides
Gastrointestinal peptide hormone involved in glucose homeostasis
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Glucagon-like_peptide-1
Class of chemical compounds
infarction, non-fatal stroke or end-stage renal disease when comparing metformin monotherapy to Thiazolidinedione for treatment of type 2 diabetes. Thiazolidinediones
Thiazolidinedione
Chemical compound
monotherapy and as a fixed dose combination with either sitagliptin or with metformin. In the European Union, it was approved in March 2018, for use as a monotherapy
Ertugliflozin
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
List of commercially available insulins
List_of_commercially_available_insulins
Vitamin used in animal cell metabolism
proton-pump inhibitors, H2 blockers, or other antacids, and interaction with metformin. Elderly people due to impaired intestinal absorption, and children, premenopausal
Vitamin_B12
Chemical compound
oral antidiabetic drug of the biguanide class, chemically related to metformin and phenformin. Buformin was marketed by German pharmaceutical company
Buformin
Ultralong-acting basal insulin analogue
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_icodec
Rapid-acting man-made insulin
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_aspart
Chemical compound
by itself, in combination with metformin, in combination with metformin and a sulfonylurea, in combination with metformin and pioglitazone, or in combination
Canagliflozin
Chemical compound
recalled Chinese "herbal products" containing phenformin. The related drug metformin is considerably safer than phenformin, with three cases of lactic acidosis
Phenformin
Chemical compound
GlaxoSmithKline (GSK) as a stand-alone drug or for use in combination with metformin or with glimepiride. First released in 1999, annual sales peaked at approximately
Rosiglitazone
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Retatrutide
Use of insulin protein and analogs as medical treatment
Retrieved 4 January 2023. Foretz M, Guigas B, Viollet B (August 2023). "Metformin: update on mechanisms of action and repurposing potential". Nature Reviews
Insulin_(medication)
Medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Dapagliflozin/sitagliptin
Combination drug
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_icodec/semaglutide
Modified forms of synthetic insulin
of Insulin Tregopil and Its Permeation Enhancer on Pharmacokinetics of Metformin in Healthy Volunteers: Randomized, Open-Label, Placebo-Controlled, Crossover
Insulin_analogue
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Sotagliflozin
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Saroglitazar
Medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Dasiglucagon
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Danuglipron
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Lotiglipron
Rapid-acting insuline analog
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Insulin_lispro
Chemical compound
conclusive evidence that acarbose, when compared to diet and exercise, metformin, placebo, or no intervention, improved all-cause mortality, reduced or
Acarbose
Ultralong-acting basal insulin analogue
insulin glargine (n=251), in addition to either mealtime insulin aspart, metformin, and/or pioglitazone. Participants in this trial had an average HbA1c
Insulin_degludec
Beta-lactam antibiotic
Cefalexin also interacts with metformin, an antidiabetic drug, and this can lead to higher concentrations of metformin in the body. Histamine H2 receptor
Cefalexin
Combination drug
Dapagliflozin/saxagliptin/metformin, sold under the brand name Qternmet XR among others, is a fixed-dose combination anti-diabetic medication used as
Dapagliflozin/saxagliptin/metformin
Dapagliflozin/saxagliptin/metformin
Israeli geneticist
genetics influence lifespan. He has also proposed metformin as a tool to target aging and has run the Metformin in Longevity Study (completed May 2018) He is
Nir_Barzilai
Chemical compound
gemigliptin/metformin and metformin groups. The mean daily doses of metformin at week 24 were 1,699 and 1,868 mg for the gemigliptin/metformin group and
Gemigliptin
Chemical compound
diabetes. Combination therapy with saxagliptin and metformin was more effective than saxagliptin or metformin monotherapy. When the relative benefits of increasing
Saxagliptin
Chemical compound
cannot be controlled by proper dietary management and exercise and when metformin has already been tried. National Kidney Foundation (2012 Update) claims
Gliclazide
Chemical compound
production of glucagon by the pancreas. It is generally less preferred than metformin and sulfonylureas as an initial treatment. It is taken by mouth. Common
Linagliptin
Combination drug
years and older with type 2 diabetes: to improve glycemic control when metformin with or without sulphonylurea (SU) and either saxagliptin or dapagliflozin
Dapagliflozin/saxagliptin
Short-acting insulin formulation
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Regular_insulin
Biosynthesis of glucose molecules
increased levels of hyperglycemia in the body. The anti-diabetic drug metformin reduces blood glucose primarily through inhibition of gluconeogenesis
Gluconeogenesis
Alpha-glucosidase inhibitor
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Voglibose
Management of diabetes
most common drugs used in T2D, metformin is the drug of choice to help patients lower their blood sugar levels. Metformin is an example of a class of medicine
Diabetes_management
Species of fish native to Thailand
Betta splendens' behavior is metformin, which is a drug doctors prescribe to treat people with type II diabetes. Metformin can enter freshwater and wastewater
Siamese_fighting_fish
Drug
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
PPAR_agonist
Diabetes medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Pramlintide
Diabetes drug
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Lixisenatide
Medical condition
weight or insulin sensitivity may coincide with changes in the skin. Metformin, which is widely used for insulin resistance and type 2 diabetes, has
Acanthosis_nigricans
High blood sugar levels during pregnancy
diabetes is treated with a diabetic diet, exercise, medication (such as metformin), and sometimes insulin injections. Most people manage blood sugar with
Gestational_diabetes
Chemical compound
its potential use in cancer treatment. Chemically, it is derivative of metformin and a potent oxidative phosphorylation inhibitor and AMP-activated protein
HL156A
Failure to ovulate during a menstrual cycle
largest trial to date, comparing clomiphene with metformin, clomiphene was more effective than metformin alone. Following this study, the ESHRE/ASRM-sponsored
Anovulation
Medical condition
Toxins (Ethylene glycol, methanol, as well as drugs, such as aspirin, Metformin) The mnemonic for toxins is ACE GIFTs: Aspirin, Cyanide, Ethanolic ketosis
High anion gap metabolic acidosis
High_anion_gap_metabolic_acidosis
Disorder resulting from low blood levels of vitamin B12
as long-term use of proton pump inhibitors, H2-receptor blockers, and metformin, and some genetic disorders. Deficiency can also be caused by inadequate
Vitamin_B12_deficiency
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Glipizide
Tissue damage after return of blood supply following ischemia or hypoxia
published in the Journal of Cardiovascular Pharmacology suggest that Metformin may prevent cardiac reperfusion injury by inhibition of Mitochondrial
Reperfusion_injury
Autosomal recessive metabolic disorder
certain groups of MSUD patients and may be a possible adjunctive treatment. Metformin, a drug used for weight loss in diabetes patients, has been shown to reduce
Maple_syrup_urine_disease
Intermediate acting insulin formulation
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
NPH_insulin
Pharmaceutical drug
the treatment of type 2 diabetes in adults. It can be used alone (if metformin therapy is ineffective or not tolerated) or in combination with other
Albiglutide
Chemical compound
alternatives. Research on galegine eventually led to the development of metformin which is used today for treatment of type 2 diabetes. Nitensidine D Oldham
Galegine
Medication
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Velagliflozin
Medication for overactive bladder
their development as weight loss drugs. A combination of mirabegron and metformin was studied in mice and caused greater weight loss than either drug alone
Mirabegron
Dopamine agonist medication
and Volbro. As of July 2017 it was also sold as a combination drug with metformin as Diacriptin-M, and as a veterinary drug under the brand Pseudogravin
Bromocriptine
Chemical compound
samples of the diabetes drug metformin for NDMA. The FDA announcement followed a recall of three versions of metformin in Singapore, and the European
N-Nitrosodimethylamine
Chemical compound
remogliflozin etabonate, either 500 mg or 750 mg BID (twice a day), with metformin 2000 mg BID was safe and effective in patients with type 2 diabetes mellitus
Remogliflozin_etabonate
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Miglitol
Chemical substance
infarction, non-fatal stroke or end-stage renal disease when comparing metformin monotherapy to meglitinide for the treatment of type 2 diabetes. They
Meglitinide
Chemical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
Imeglimin
Pharmaceutical compound
of Insulin Tregopil and Its Permeation Enhancer on Pharmacokinetics of Metformin in Healthy Volunteers: Randomized, Open-Label, Placebo-Controlled, Crossover
Insulin_tregopil
Pharmaceutical compound
Empagliflozin/metformin Gemigliptin/rosuvastatin Glibenclamide (glyburide)/metformin Glimepiride/rosiglitazone Linagliptin/metformin Metformin/acarbose Metformin/ertugliflozin
CT-868
Group of endocrine diseases characterized by high blood sugar levels
therapy (insulin injections), while anti-diabetic medications (such as metformin and semaglutide or tirzepatide) and lifestyle modifications can be used
Diabetes
METFORMIN
METFORMIN
METFORMIN
METFORMIN
Surname or Lastname
English
English : from a personal name that has the same origin as Jacob. However, among English speakers, it is now felt to be a separate name in its own right. This is largely because in the Authorized Version of the Bible (1611) the form James is used in the New Testament as the name of two of Christ’s apostles (James the brother of John and James the brother of Andrew), whereas in the Old Testament the brother of Esau is called Jacob. The form James comes from Latin Jacobus via Late Latin Jac(o)mus, which also gave rise to Jaime, the regular form of the name in Spanish (as opposed to the learned Jacobo). See also Jack and Jackman. This is a common surname throughout the British Isles, particularly in South Wales.
Boy/Male
Hindu, Indian, Kannada, Marathi, Sanskrit
Priceless
Girl/Female
Indian
One who plays at flute
Girl/Female
Indian, Tamil
Goddess Amman
Boy/Male
Hindu
Young girl
Boy/Male
Indian, Punjabi, Sikh
Preserver of Modesty
Boy/Male
Hindu
Generous
Boy/Male
Hindu, Indian, Marathi, Oriya, Punjabi, Sanskrit, Sikh
Clouds who Give Rain; A Star; Clouds
Boy/Male
Hindu, Indian, Kannada, Malayalam, Marathi, Tamil, Telugu
Kind; God; Victory; Kind Hearted
Girl/Female
Sanskrit
Little goddess. From the mythological Hindu 'Devi'.
METFORMIN
METFORMIN
METFORMIN
METFORMIN
METFORMIN