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Chemical compound
Fidarestat (SNK-860) is an aldose reductase inhibitor under investigation for treatment of diabetic neuropathy. Aldose reductase inhibitor for treatment
Fidarestat
Gastrointestinal peptide hormone involved in glucose homeostasis
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Glucagon-like_peptide-1
Medication used to treat diabetes
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Metformin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Retatrutide
Anti-diabetic and anti-obesity medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Semaglutide
Diabetes medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Dapagliflozin
Anti-diabetic and anti-obesity medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Tirzepatide
Chemical compound
(ARI) target this enzyme. Out of the many ARIs developed, ranirestat and fidarestat are in the trial stage. Others have been discarded due to unacceptable
Epalrestat
Enzyme blocker and diabetes treatment drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Dipeptidyl peptidase-4 inhibitor
Dipeptidyl_peptidase-4_inhibitor
Cellular therapy medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Donislecel
Anti-obesity medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Orforglipron
Ultralong-acting basal insulin analogue
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_degludec
Pharmaceutical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Brenipatide
Diabetes medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Empagliflozin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Sorbinil
Long-acting insulin
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_glargine
Oral anti-diabetic drugs
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Alpha-glucosidase_inhibitor
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Danuglipron
Diabetes medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Sitagliptin
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
List of commercially available insulins
List_of_commercially_available_insulins
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Pioglitazone
Diabetes medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Dulaglutide
Intermediate acting insulin formulation
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
NPH_insulin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Sotagliflozin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Buformin
Class of organic compounds used in medicine and agriculture
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Sulfonylurea
Anti-diabetic medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Liraglutide
Short-acting insulin formulation
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Regular_insulin
Class of medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
SGLT2_inhibitor
Rapid-acting insulin analogue
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_glulisine
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Linagliptin
Ultralong-acting basal insulin analogue
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_icodec
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Retagliptin
Medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Dapagliflozin/sitagliptin
Rapid-acting man-made insulin
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_aspart
Antidiabetic medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Bexagliflozin
Class of drugs used to treat diabetes
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
GLP1_poly-agonist_peptides
Medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Exenatide
Anti-diabetic drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Alogliptin
Experimental insulin analogue
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Selenoinsulin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Biguanide
Class of chemical compounds
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Thiazolidinedione
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Enavogliflozin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Canagliflozin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Trelagliptin
Use of insulin protein and analogs as medical treatment
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_(medication)
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Vildagliptin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Glipizide
Medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_efsitora_alfa
Drugs that lower blood glucose levels to treat diabetes
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Diabetes_medication
Combination drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Empagliflozin/linagliptin/metformin
Empagliflozin/linagliptin/metformin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Acarbose
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Lotiglipron
Drug used for the treatment of symptoms of metabolic syndrome
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
PPAR_agonist
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Saroglitazar
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Glibenclamide
GLP1 poly-agonist drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Mazdutide
Combination medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin degludec/insulin aspart
Insulin_degludec/insulin_aspart
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Gliclazide
Modified forms of synthetic insulin
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_analogue
Pharmaceutical drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Albiglutide
Dopamine agonist medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Bromocriptine
Pharmaceutical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Conveglipron
Long-acting form of insulin
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Ultralente_insulin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Ertugliflozin
Medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Glimepiride
Combination drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Sitagliptin/simvastatin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Saxagliptin
Medical drug
damage which leads to retinopathy and neuropathy. Alrestatin Epalrestat Fidarestat Imirestat Lidorestat Minalrestat Ponalrestat Ranirestat Salfredin B11
Aldose_reductase_inhibitor
Long-acting man-made insulin
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_detemir
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Rivoglitazone
Two drugs combined to treat diabetes
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Dapagliflozin/metformin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Miglitol
Pharmaceutical drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Empagliflozin/metformin
Medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Dasiglucagon
Rapid-acting insuline analog
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_lispro
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Rosiglitazone
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Repaglinide
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Ipragliflozin
Pharmaceutical drug classification
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
ATC_code_A10
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Lobeglitazone
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Remogliflozin_etabonate
Alpha-glucosidase inhibitor
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Voglibose
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Imeglimin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Teneligliptin
Chemical substance
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Meglitinide
Medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Velagliflozin
Pharmaceutical drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Sitagliptin/metformin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Gemigliptin
Powdered insulin delivered with an inhaler
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Inhalable_insulin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Ciglitazone
Historical formulation of insulin as medication
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Lente_insulin
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Tofogliflozin
Combination drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_glargine/lixisenatide
Chemical compound
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Luseogliflozin
Pharmaceutical drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Empagliflozin/linagliptin
Combination drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Pioglitazone/metformin
Enzyme
Exisulind, Imirestat, Zopolrestat, Tolrestat, Zenarestat, Caficrestat, Fidarestat, Govorestat, Ranirestat, Ponalrestat, Risarestat, Sorbinil, and Berberine
Aldose_reductase
Combination drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Dapagliflozin/saxagliptin/metformin
Dapagliflozin/saxagliptin/metformin
Pharmaceutical drug
Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase inhibitors Acarbose
Insulin_degludec/liraglutide
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