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Chemical compound
E-6801 is a partial agonist of the 5-HT6 receptor. It enhanced recognition memory and reversed the memory deficits of scopolamine in an object recognition
E-6801
South American psychoactive decoction
non-religious adaptations, and the development of ayahuasca analogues (i.e., variants) using local or synthetic ingredients. While DMT is internationally
Ayahuasca
Sedating antidepressant
respectively. Benzodiazepines and Z-drugs generally showed larger effect sizes (e.g., SMDs of 0.45 to 0.83) than doxepin, whereas the effect sizes of orexin
Doxepin
SSRI antidepressant
NSAIDs, antiplatelet drugs, anticoagulants, omega-3 fatty acids, vitamin E, and garlic supplements must be careful when taking fluoxetine or other SSRIs
Fluoxetine
Atypical antipsychotic medication
extrapyramidal side-effect liability. Owing to the risks associated with clozapine (e.g. agranulocytosis, diabetes mellitus, etc.), clinicians often attempt treatment
Quetiapine
Medication mainly used for depression and smoking cessation
PMC 5947828. PMID 29377409. Livingstone-Banks J, Norris E, Hartmann-Boyce J, West R, Jarvis M, Chubb E, et al. (October 2019). "Relapse prevention interventions
Bupropion
Chemical element with atomic number 54 (Xe)
(PDF). Chinese Physics C. 45 (3) 030001. doi:10.1088/1674-1137/abddae. Aprile E, Abe K, Agostini F, Ahmed Maouloud S, Alfonsi M, Althueser L, et al. (August
Xenon
Antidepressant medication
situations in which antimuscarinic effects are particularly problematic (e.g., in patients with benign prostatic hyperplasia, closed-angle glaucoma,
Trazodone
Antidepressant medication
Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists
Mirtazapine
Mushrooms containing psychoactive indole alkaloids
mushrooms (in that case, among the Mexican [Nahuatl] Indians). Brande E. (1799). "Mr. E. Brande, on a poisonous species of Agaric". The Medical and Physical
Psilocybin_mushroom
Psychedelic drug found in toads, mushrooms and plants
the present, bufotenin has been considered by many experts, such as David E. Nichols, to be either inactive or only weakly active as a psychedelic in
Bufotenin
Antihistamine medication
restlessness rather than sedation. It is a first-generation H1-antihistamine (i.e. it blocks histamine) with sedative effects. Diphenhydramine is also a potent
Diphenhydramine
Psychoactive substance found in plants in the family Apocynaceae
be important, although they are correlated with some secondary measures (e.g., satisfaction in self-assessments). Ibogaine has been referred to as an
Ibogaine
Atypical antipsychotic medication
was sometimes an antagonist (e.g., at 5-HT6), sometimes an inverse agonist (e.g., 5-HT2B), sometimes a partial agonist (e.g., D2S, D3S, D4S, D2L). Aripiprazole
Aripiprazole
Psychedelic drug
effectively induce tolerance (see Subsect. E.III). Canal CE, Olaghere da Silva UB, Gresch PJ, Watt EE, Sanders-Bush E, Airey DC (April 2010). "The serotonin
Dimethyltryptamine
Atypical antipsychotic medication
doi:10.1080/14789949.2024.2396348. ISSN 1478-9949. Silva E, Legge S, Casetta C, Whiskey E, Oloyede E, Gee S (June 2025). "Understanding clozapine-related
Clozapine
Species of psychoactive cactus
S. E. & Malenka, R. C. (2001). "Addiction and the brain: The neurobiology of compulsion and its persistence." Neuroscience. 2;696 K B Nolte and R E Zumwalt
Peyote
Medication to prevent nausea and vomiting
September 2020. "Zofran Product and Consumer Medicine Information Licence". TGA eBS. Archived from the original on 29 August 2022. Retrieved 28 August 2022
Ondansetron
Atypical antipsychotic medication
olanzapine-treated patients' offspring at a heightened risk for neural tube defects (e.g. spina bifida). Breastfeeding in women taking olanzapine is advised against
Olanzapine
Synthetic Opioid pain medication
adequately to treatment with first-line medications such as dopamine agonists (e.g., pramipexole) or gabapentinoids, often due to augmentation. Tramadol, due
Tramadol
Antihistamine drug
British Medical Association. 2017. p. X. ISBN 978-0-85711-298-9. Shorter E (2009). Before Prozac: the troubled history of mood disorders in psychiatry
Hydroxyzine
Beta blocker drug
Propranolol is useful in the treatment of acute cardiovascular toxicity (e.g. in overdose) caused by sympathomimetics like amphetamine, methamphetamine
Propranolol
Psychedelic drug
of consciousness are attributable to the 5-HT2A receptor". eLife. 7 e35082. doi:10.7554/eLife.35082. PMC 6202055. PMID 30355445. Nichols DE (April 2016)
LSD
Structures and Bibliographies. Springer. pp. 192–. ISBN 978-1-4757-2085-3. "TGA eBS - Product and Consumer Medicine Information Licence". "Anksilon (Orion Pharma
Buspirone
Monoamine neurotransmitter
with E. histolytica have been found to have highly elevated serum serotonin levels, which returned to normal following resolution of the infection. E. histolytica
Serotonin
Muscle relaxant medication
substances may interact with cyclobenzaprine: Central nervous system depressants (e.g. alcohol, opioids, benzodiazepines, nonbenzodiazepines, phenothiazines,
Cyclobenzaprine
Serotonin modulator antidepressant
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Vortioxetine
Medication mainly used to treat gout
number of chromosomes (i.e., tetraploid instead of diploid), and lead to cell nuclei with double the usual number of chromosomes (i.e., tetraploid instead
Colchicine
Psychedelic drug
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5-MeO-DMT
CHCl3, historical anaesthetic and common solvent
(This had caused me to impose the name "chloroform" upon this substance [i.e., formyl chloride or chloride of formic acid].) In 1835, Dumas prepared the
Chloroform
Medication used for high blood pressure and ADHD
clinical data are yet not available.368–370 Cichero E, Francesconi V, Casini B, Casale M, Kanov E, Gerasimov AS, et al. (2023). "Discovery of Guanfacine
Guanfacine
Species of flowering plant
improvements in sleep and mild nervous tension symptoms. Germany's Commission E, the scientific advisory board responsible for evaluating the safety and efficacy
Valerian_(herb)
Typical antipsychotic medication
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Chlorpromazine
Chemical compound found in some species of mushrooms
doi:10.1016/j.aca.2004.08.071. Lindenblatt H, Krämer E, Holzmann-Erens P, Gouzoulis-Mayfrank E, Kovar KA (May 1998). "Quantitation of psilocin in human
Psilocybin
Antipsychotic medication
autism spectrum disorder. It is taken either by mouth or by injection (i.e., subcutaneous or intramuscular). The injectable versions are long-acting
Risperidone
Phytocannabinoid discovered in 1940
"Cannabidiol interactions with voltage-gated sodium channels". eLife. 9 e58593. doi:10.7554/eLife.58593. PMC 7641581. PMID 33089780. Nadulski T, Pragst F
Cannabidiol
Tricyclic antidepressant
it is frequently used to treat painful paresthesias in the arms and legs (e.g., burning sensations, pins and needles, stabbing pains) caused by damage
Amitriptyline
Type of medication
Liebowitz MR, Quitkin FM, Stewart JW, McGrath PJ, Harrison W, Rabkin J, Tricamo E, Markowitz JS, Klein DF (July 1984). "Phenelzine v imipramine in atypical
Monoamine_oxidase_inhibitor
Chemical compound
ISBN 978-3-642-73225-6. PMID 3293039. Barrett RJ, Blackshear MA, Sanders-Bush E (1982). "Discriminative stimulus properties of L-5-hydroxytryptophan: behavioral
5-Hydroxytryptophan
Common name for more than 1,000 species of flowering plants in the family Convolvulaceae
cold. Some species are strictly annual (e.g. Ipomoea nil), producing many seeds, and some perennial species (e.g. I. indica) are propagated by cuttings
Morning_glory
Drug combination prescribed for weight loss; later withdrawn from market
Children". The New York Times. p. 21. Retrieved September 23, 2023. Hayward E (6 May 1997). "Diet to Death". Boston Herald. p. 1. Archived from the original
Fenfluramine/phentermine
DMT-infused smoking blend
methysergide) Hypidone Serotonin (5-HT) Tryptamines (e.g., 2-Me-5-HT, 5-BT, 5-CT, 5-MT, Bufotenin, E-6801, E-6837, EMD-386088, EMDT, LY-586713, N-Me-5-HT, ST-1936
Changa_(drug)
Class of pharmaceutical drugs
(5‐HT1A/B/E/F and 5‐HT7), GTPγS (5‐HT1A/B/D/E/F), and IP (5‐HT2) assays of individual antimigraine drugs at 5‐HT receptors [...] Bigal, M. E.; Bordini
Triptan
Psychedelic drug
Meshi E, Nagaeva E, Öhman T, Róg T, Kankuri E, Vilar M, Varjosalo M, Korpi ER, Permi P, Mineev KS, Saarma M, Vattulainen I, Casarotto PC, Castrén E (June
Psilocin
Naturally occurring psychedelic compound
self-rated most important phenethylamine compounds together with Mescaline, 2C-E, 2C-T-7, and 2C-T-2. Bryan Wynter produced Mars Ascends after trying the substance
Mescaline
Serotonin receptor agonist
methysergide) Hypidone Serotonin (5-HT) Tryptamines (e.g., 2-Me-5-HT, 5-BT, 5-CT, 5-MT, Bufotenin, E-6801, E-6837, EMD-386088, EMDT, LY-586713, N-Me-5-HT, ST-1936
4-Hydroxytryptamine
Chemical compound
Biochemical Pharmacology. 45 (11): 2337–41. doi:10.1016/0006-2952(93)90208-E. PMID 8517875. Kaumann AJ (June 1983). "Yohimbine and rauwolscine inhibit
Yohimbine
Chemical compound
modified bacteria such as B. amyloliquefaciens, B. subtilis, C. glutamicum or E. coli. These strains carry mutations that prevent the reuptake of aromatic
Tryptophan
Psychedelic drug
other closely related members of the 2C series, including 2C-C, 2C-D, 2C-E, 2C-I, and 2C-T-2, all showed no activity as monoamine releasing agents of
2C-B
Chemical compound
Last Updated on eMC Dec 23, 2013 Sayyah-Melli M, Tehrani-Gadim S, Dastranj-Tabrizi A, Gatrehsamani F, Morteza G, Ouladesahebmadarek E, et al. (August
Cabergoline
Atypical antipsychotic
methysergide) Hypidone Serotonin (5-HT) Tryptamines (e.g., 2-Me-5-HT, 5-BT, 5-CT, 5-MT, Bufotenin, E-6801, E-6837, EMD-386088, EMDT, LY-586713, N-Me-5-HT, ST-1936
Lumateperone
Analgesic medication
Health. Retrieved 14 August 2017. Gregori-Puigjané E, Setola V, Hert J, Crews BA, Irwin JJ, Lounkine E, et al. (July 2012). "Identifying mechanism-of-action
Nefopam
Chemical compound
PMID 31909513. Zamberlan F, Sanz C, Martínez Vivot R, Pallavicini C, Erowid F, Erowid E, et al. (2018). "The Varieties of the Psychedelic Experience: A Preliminary
4-HO-MET
Antihistamine medication
inhibits mast cells from lung and tonsillar tissues when stimulated via an IgE-dependent histamine release mechanism. However, neither ketotifen nor disodium
Ketotifen
Psychoactive drug, often called ecstasy
spiritual practices. MDMA has become widely known as ecstasy (shortened "E", "X", or "XTC"), usually referring to its tablet form, although this term
MDMA
Medication
ISBN 978-0-9757919-2-9. "Metoclopramide Hydrochloride 5mg/5ml Oral Solution - - (eMC)". xpil.medicines.org.uk. Archived from the original on 3 March 2016. Retrieved
Metoclopramide
Chemical compound
substituent is present in many important alkaloids, known as indole alkaloids (e.g., tryptophan and auxins), and it remains an active area of research today
Indole
Typical antipsychotic medication
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Haloperidol
Weight loss medication
No. 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists
Phentermine
Entactogen, stimulant, and psychedelic drug of the amphetamine family
robust self-report VAS changes in both MDMA-like (e.g., "closeness to others") and hallucinogen-like (e.g., "familiar things seem unfamiliar", time distortions
3,4-Methylenedioxyamphetamine
Sedating antihistamine
1016/j.ejmech.2016.03.045. PMID 27043269. Bolshan Y, Getlik M, Kuznetsova E, Wasney GA, Hajian T, Poda G, et al. (March 2013). "Synthesis, Optimization
Promethazine
Antihistamine medication
National Library of Medicine. De Bruyne P, Christiaens T, Boussery K, Mehuys E, Van Winckel M (January 2017). "Are antihistamines effective in children?
Cyproheptadine
Serotonin dopamine partial agonist atypical antipsychotic
Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists
Brexpiprazole
Chemical compound
1177/0333102410370873. PMID 20855361. Rubio-Beltrán E, Labastida-Ramírez A, Haanes KA, van den Bogaerdt A, Bogers AJ, Zanelli E, Meeus L, Danser AH, Gralinski MR, Senese
Naratriptan
Blood pressure medication
bleeds. Carvedilol is used in the treatment of acute cardiovascular toxicity (e.g. overdose) with sympathomimetics, for instance caused by amphetamine, methamphetamine
Carvedilol
Substituted cathinone stimulant drug
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N-Ethylpentylone
Atypical antipsychotic medication
plasma concentrations may be increased when combined with CYP3A4 inhibitors (e.g. ketoconazole, clarithromycin, ritonavir, and voriconazole) possibly leading
Lurasidone
Medication used for the treatment of migraine headaches
1177/0333102410370873. PMID 20855361. Rubio-Beltrán E, Labastida-Ramírez A, Haanes KA, van den Bogaerdt A, Bogers AJ, Zanelli E, et al. (December 2019). "Characterization
Rizatriptan
Class of compounds based upon the amphetamine structure
α-alkyltryptamines PiHKAL The Shulgin Index Hagel JM, Krizevski R, Marsolais F, Lewinsohn E, Facchini PJ (2012). "Biosynthesis of amphetamine analogs in plants". Trends
Substituted_amphetamine
Medication used for migraines & cluster headaches
weeks. Concurrent use with other triptans or ergot-containing medications (e.g., ergotamine, dihydroergotamine) within 24 hours can result in additive
Sumatriptan
Class of pharmaceutical drugs
conditions. Some atypical antipsychotics have received regulatory approval (e.g. by the FDA of the US, the TGA of Australia, the MHRA of the UK) for schizophrenia
Atypical_antipsychotic
C2HCl3, widely used industrial solvent
Einfach-Chlorkohlenstoff, Fischer, E. (1864) in Zeitschrift für Chemie. page 268 Waters, E. M.; Gerstner, H. B.; Huff, J. E. (January 1977). "Trichloroethylene
Trichloroethylene
Chemical compound
ISSN 0021-9673. Ramstad E (1968). "Chemistry of alkaloid formation in ergot". Lloydia. 31: 327–341. Kleinerová E, Kybal J (September 1973). "Ergot
Ergine
Dopamine agonist medication
PMID 10903391. Clemens, J. A., Kornfeld, E. C., Phebus, L. A., Shaar, C. J., Smalstig, E. B., Cassady, J. M., ... & Kelly, E. (1982). Dopaminergic Agents Related
Ropinirole
Atypical antipsychotic medication
Pharmaceuticals, 19-CV-04629 (E.D.N.Y. February 16, 2021). Gioia v. Patterson, Belknap, Webb & Tyler, 2:23-cv-08163 (E.D.N.Y. April 19, 2024). Allimadi
Paliperidone
Pharmaceutical compound
methysergide) Hypidone Serotonin (5-HT) Tryptamines (e.g., 2-Me-5-HT, 5-BT, 5-CT, 5-MT, Bufotenin, E-6801, E-6837, EMD-386088, EMDT, LY-586713, N-Me-5-HT, ST-1936
3,4,5-Trimethoxyamphetamine
Neurotransmission-modulating substance
been approved for medical use. Selective 5-HT6 receptor agonists like E-6801, E-6837, EMDT, WAY-181,187, and WAY-208,466 show antidepressant, anxiolytic
Serotonin_receptor_agonist
Chemical compound
2016.11.004. PMID 27890676. S2CID 30943496. Shimshoni JA, Winkler I, Golan E, Nutt D (January 2017). "Neurochemical binding profiles of novel indole and
5-MAPB
Atypical antipsychotic medicine
S240860. PMC 8126799. PMID 34012253. Tarchi L, Bugini S, Dani C, Cassioli E, Rossi E, Lucarelli S, et al. (December 2024). "Efficacy of Cariprazine in the
Cariprazine
Atypical antipsychotic and antiemetic medication
Pheochromocytoma Concomitant prolactin-dependent tumours e.g. prolactinoma, breast cancer Movement disorders (e.g. Parkinson's disease and dementia with Lewy bodies)
Amisulpride
Metabolite of the amino acid tryptophan
doi:10.21203/rs.3.rs-2667175/v1. Retrieved 18 March 2025. Egan C, Grinde E, Dupre A, Roth BL, Hake M, Teitler M, et al. (February 2000). "Agonist high
Tryptamine
Chemical compound in the ergot family of alkaloids
antibiotics (e.g., erythromycin), certain HIV protease inhibitors (e.g., ritonavir, nelfinavir, indinavir), certain azole antifungals (e.g., ketoconazole
Ergotamine
Group of chemical compounds
Saro G, Johne S, Latino DA, Moine F, van der Toorn M, Mathis C, Veljkovic E (March 2025). "Monoamine Oxidase Inhibitors Present in Tobacco Modulate Dopamine
Β-Carboline
Psychedelic drug
relatively novel synthetic derivatives of phenethylamines (i.e., mescaline analogs) and tryptamines (i.e., DMT analogs). A frequently cited example is that of
DiPT
Antidepressant medication
Biochem. Pharmacol. 45 (11): 2352–4. doi:10.1016/0006-2952(93)90211-e. PMID 8100134. Weber E, Sonders M, Quarum M, McLean S, Pou S, Keana JF (1986). "1
Nortriptyline
Pharmaceutical compound
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2,5-Dimethoxy-4-methylamphetamine
2,5-Dimethoxy-4-methylamphetamine
Medication
1038/sj.bjp.0705341. PMC 1573953. PMID 12890707. Borsini F, Giraldo E, Monferini E, Antonini G, Parenti M, Bietti G, et al. (September 1995). "BIMT 17
Flibanserin
Chemical compound
described in the scientific literature by 2021. It was developed by David E. Olson and colleagues at the University of California, Davis and Delix Therapeutics
Zalsupindole
Pharmaceutical compound
methysergide) Hypidone Serotonin (5-HT) Tryptamines (e.g., 2-Me-5-HT, 5-BT, 5-CT, 5-MT, Bufotenin, E-6801, E-6837, EMD-386088, EMDT, LY-586713, N-Me-5-HT, ST-1936
4-Fluorotryptamine
Medication used to treat Alzheimer's disease
or have a contraindication to AChE (acetylcholinesterase) inhibitors. One guideline recommends memantine or an AChE inhibitor be considered in people
Memantine
Chemical compound
February 2018. Clayton BD, Willihnganz M (2016). Basic Pharmacology for Nurses – E-Book. Elsevier Health Sciences. pp. 210–211. ISBN 978-0-323-37697-6. Dressler
Apomorphine
Antidepressant medication
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Vilazodone
Pharmaceutical compound
2C-E, also known as 4-ethyl-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally. The drug acts
2C-E
Chemical compound
1177/02698811251378512. hdl:1887/4298848. PMID 41099491. Hughes Z, Christian E, Dvorak D, Umbricht D, Winters J, Raines S, et al. (December 2023). "ACNP
Bretisilocin
Pharmacodynamics and pharmacokinetics of ethanol
drunkenness developed into a major problem for public health. In 1874, Francis E. Anstie's experiments showed that the amounts of alcohol eliminated unchanged
Pharmacology_of_ethanol
Medication for nausea, psychosis, and anxiety
Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists
Prochlorperazine
Chemical class of organic compounds
a.k.a. DOM), entactogen (e.g. MDA), appetite suppressants (e.g. phentermine), nasal decongestants and bronchodilators (e.g., levomethamphetamine and
Substituted_phenethylamine
Group of four possible stereoisomers found in various plants: a.o., absinthe and mint
1016/j.phytochem.2004.08.019. PMID 15381410. Foster, Adam J.; Hall, Dawn E. (Apr 2013). "Identification of Genes in Thuja plicata Foliar Terpenoid Defenses"
Thujone
General anaesthetic
Nº 784 — Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 — Lists
Halothane
Psychoactive drug taken by mouth
by 1978. It was described in a paper authored by Alexander Shulgin, David E. Nichols, and other colleagues. As an enantiomer of MDMA, (R)-MDMA is a Schedule
(R)-MDMA
E 6801
E 6801
Boy/Male
American, British, English
Birch
Female
French
Feminine form of French Honoré, HONORÉE means "honor, valor."
Female
French
Feminine form of French unisex Esmé, ESMÉE means "esteemed, loved."
Female
French
French form of Latin Medea, MÉDÉE means "cunning."
Boy/Male
American, British, English
Bird
Female
French
Feminine form of French André, ANDRÉE means "man; warrior."
Boy/Male
English, Modern
A Miracle; Inimitably; Do Something which Others cannot do
Female
French
Pet form of French Estelle, ESTÉE means "star."
Female
French
Feminine form of French Désiré, DÉSIRÉE means "desired."Â
Girl/Female
French, German, Latin
Virgin
Male
French
French form of Latin Timotheus, TIMOTHÉE means "to honor God."
Female
French
French form of Latin Dorothea, DOROTHÉE means "gift of God."
Girl/Female
French, German, Latin, Spanish
Modest
Male
French
French form of Latin Isaias, ISAÃE means "God is salvation."
Female
French
Feminine form of French Dieudonné, DIEUDONNÉE means "God-given."
Male
Slovene
Pet form of Slovene Jožef, JOŽE means "(God) shall add (another son)."Â
Female
French
Feminine form of French René, RENÉE means "reborn."
Female
French
French name, derived from the French word aimée, AIMÉE means "much loved."
Female
French
French feminine form of Latin Josephus, JOSÉE means "(God) shall add (another son)."Â
Female
French
Feminine form of French Iréné, IRÉNÉE means "peaceful."
E 6801
E 6801
Boy/Male
Arabic, Muslim
Lamp of the State
Female
Egyptian
, Bast.
Boy/Male
Hindu, Indian
Shy
Boy/Male
Shakespearean
The Tragedy of Othello, Moor of Venice' Lieutenant to Othello.
Girl/Female
Latin
Rebirth.
Boy/Male
Bengali, Gujarati, Hindu, Indian, Jain, Kannada, Mythological, Sanskrit, Sindhi, Tamil, Traditional
Lord Buddha
Girl/Female
Norse
Protection.
Boy/Male
Arabic
Ruler of Nation; Leader; Firmly; Strong
Boy/Male
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi
Come
Boy/Male
English
Farm land.
E 6801
E 6801
E 6801
E 6801
E 6801
a.
Old; as, Auld Reekie (old smoky), i. e., Edinburgh.
n.
An evergreen shrub of the genus Erica (E. passerina).
n.
See Elevator, n. (e).
n.
A female pope; i. e., the fictitious pope Joan.
a.
Covered with a mant/e; cloaked; disguised.
a.
Lower by a semitone; flat; as, E molle, that is, E flat.
a.
Bold; brave; stout; daring; resolu?e; intrepid.
v. t.
To liken; to compa/e.
n.
See Set, n., 2 (e) and 3.
e. i.
To cut with a grating sound; to cut; to penetrate or pierce harshly; as, the griding sword.
superl.
Possessing a characteristic quality in a supreme or superior degree; as, high (i. e., intense) heat; high (i. e., full or quite) noon; high (i. e., rich or spicy) seasoning; high (i. e., complete) pleasure; high (i. e., deep or vivid) color; high (i. e., extensive, thorough) scholarship, etc.
e
(imp.) of Wit
n.
Originally, the highest note in the scale of Guido; hence, proverbially, any extravagant saying.
superl.
Not decidedly marked; not forcible; inconsiderable; unimportant; insignificant; not severe; weak; gentle; -- applied in a great variety of circumstances; as, a slight (i. e., feeble) effort; a slight (i. e., perishable) structure; a slight (i. e., not deep) impression; a slight (i. e., not convincing) argument; a slight (i. e., not thorough) examination; slight (i. e., not severe) pain, and the like.
pl.
of Notopodium
e. t.
To make cool.