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AKT2

  • AKT2
  • Protein found in humans

    AKT2, also known as RAC-beta serine/threonine-protein kinase, is an enzyme that in humans is encoded by the AKT2 gene. It influences metabolite storage

    AKT2

    AKT2

    AKT2

  • Protein kinase B
  • Set of three serine threonine-specific protein kinases

    isoforms of protein kinase B. These three genes are referred to as AKT1, AKT2, and AKT3 and encode the RAC alpha, beta, and gamma serine/threonine protein

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • Arctic fox
  • Species of fox

    murine thymoma viral oncogene homolog 2 (AKT2). GLTPD1 is involved in the fatty acid metabolism, while AKT2 pertains to the glucose metabolism and insulin

    Arctic fox

    Arctic fox

    Arctic_fox

  • PHLPP
  • Class of enzymes

    PHLPP2, that are important regulators of Akt serine-threonine kinases (Akt1, Akt2, Akt3) and conventional/novel protein kinase C (PKC) isoforms. PHLPP may

    PHLPP

    PHLPP

  • Familial partial lipodystrophy
  • Medical condition

    associated with FPL have been reported in LMNA (lamin A/C), PPARG (PPARγ), AKT2 (AKT serine/threonine kinase 2), PLIN1 (perilipin-1), and CIDEC (cell-death-inducing

    Familial partial lipodystrophy

    Familial_partial_lipodystrophy

  • MTOR
  • Mammalian protein found in humans

    spontaneous apoptosis (AKT1), severe diabetes (AKT2), small brains (AKT3), and growth deficiency (AKT1/AKT2). Mice heterozygous for AKT1 have increased lifespan

    MTOR

    MTOR

    MTOR

  • MK-2206
  • Chemical compound

    selective inhibitor of pan-Akt, namely, of all three Akt isoforms Akt1, Akt2, and Akt3. It is intended to be used with other cancer therapies that advanced

    MK-2206

    MK-2206

    MK-2206

  • AKT1
  • Protein-coding gene in humans

    serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid

    AKT1

    AKT1

    AKT1

  • AKT (disambiguation)
  • Topics referred to by the same term

    Finnish music organization Karat (airline) (ICAO: AKT), in Russia AKT1, AKT2, or AKT3, enzymes Erich Akt (1898–?), German politician Akolet language (ISO

    AKT (disambiguation)

    AKT_(disambiguation)

  • Titin
  • Largest known protein in human muscles

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Titin

    Titin

    Titin

  • Ovarian cancer
  • Cancer originating in or on the ovary

    subtypes Gene mutated Mutation type Subtype Prevalence AKT1 amplification 3% AKT2 amplification/mutation 6%, 20% ARID1A point mutation endometrioid and clear-cell

    Ovarian cancer

    Ovarian cancer

    Ovarian_cancer

  • Akt/PKB signaling pathway
  • Series of biochemical reactions

    doi:10.1038/ncb839. PMID 12172553. S2CID 11880801. Chin YR, Toker A (2010). "Akt2 regulates expression of the actin-bundling protein palladin". FEBS Lett.

    Akt/PKB signaling pathway

    Akt/PKB_signaling_pathway

  • NLK
  • Mammalian protein found in Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    NLK

    NLK

    NLK

  • TCL1 MTCP1 protein domain
  • Protein domain

    membrane potential. This protein exists as a homodimer. It interacts with AKT1, AKT2 and AKT3 via the PH protein domain. It interacts with PNPT1; the interaction

    TCL1 MTCP1 protein domain

    TCL1 MTCP1 protein domain

    TCL1_MTCP1_protein_domain

  • AMP-activated protein kinase
  • Class of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • PI3K/AKT/mTOR pathway
  • Cell cycle regulation pathway

    integral signaling node of the PAM pathway. There are three Akt isozymes, Akt1, Akt2 and Akt3. Small-molecule inhibitors of Akt1 could be especially useful to

    PI3K/AKT/mTOR pathway

    PI3K/AKT/mTOR pathway

    PI3K/AKT/mTOR_pathway

  • TBC1D4
  • Protein-coding gene in the species Homo sapiens

    discovered in a screen for novel substrates of the serine-threonine kinase Akt2, which phosphorylates AS160 at Thr-642 and Ser-588 after insulin stimulation

    TBC1D4

    TBC1D4

    TBC1D4

  • CUX1
  • Animal gene

    PI3K–AKT signaling pathway by insulin-like growth factor 1 (IGF1) or by AKT2 overexpression led to the upregulation of CUX1 and was associated with resistance

    CUX1

    CUX1

  • PANTHER
  • workflow using an example of a small gene list containing three genes AKT1, AKT2, AKT3. We first type these gene names within the box and separate them by

    PANTHER

    PANTHER

  • P38 mitogen-activated protein kinases
  • Protein family

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    P38 mitogen-activated protein kinases

    P38_mitogen-activated_protein_kinases

  • Mitogen-activated protein kinase
  • P38 mitogen-activated protein kinases

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Mitogen-activated protein kinase

    Mitogen-activated_protein_kinase

  • Gene duplication
  • Duplication of a gene sequence within a genome

    cancer CCND1 13% Neuroblastoma MYCN 20–25% Ovarian cancer MYC 20–30% ERBB2 15–30% AKT2 12% Sarcoma MDM2 10–30% CDK4 10% Small cell lung cancer MYC 15–20%

    Gene duplication

    Gene_duplication

  • Protein kinase domain
  • Protein domain

    ABL1 ; ABL2 ; ACVR1 ; ACVR1B ; ACVR1C ; ACVR2A ; ACVR2B ; ACVRL1 ; AKT1 ; AKT2 ; AKT3 ; ALK ; AMHR2 ; ANKK1 ; ARAF ; AURKA ; AURKB ; AURKC ; AXL ; BLK ;

    Protein kinase domain

    Protein kinase domain

    Protein_kinase_domain

  • Cell division cycle 7-related protein kinase
  • Protein found in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Cell division cycle 7-related protein kinase

    Cell division cycle 7-related protein kinase

    Cell_division_cycle_7-related_protein_kinase

  • Protein kinase N1
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Protein kinase N1

    Protein kinase N1

    Protein_kinase_N1

  • IDH3A
  • Protein-coding gene in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    IDH3A

    IDH3A

    IDH3A

  • GSK484
  • Pharmaceutical compound

    marrow neutrophils up-regulates macrophage osteoclastogenesis via cGAS-STING/AKT2 pathway to promote osteoporosis". Experimental Cell Research. 446 (2) 114477

    GSK484

    GSK484

    GSK484

  • Fusion gene
  • Gene formed by the combination of two independent genes

    are found from hematological cancers, sarcomas, and prostate cancer. BCAM-AKT2 is a fusion gene that is specific and unique to high-grade serous ovarian

    Fusion gene

    Fusion gene

    Fusion_gene

  • Anti-Müllerian hormone type-2 receptor
  • Protein receptor for anti-Müllerian hormone

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Anti-Müllerian hormone type-2 receptor

    Anti-Müllerian hormone type-2 receptor

    Anti-Müllerian_hormone_type-2_receptor

  • P70-S6 Kinase 1
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • TTK (gene)
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    TTK (gene)

    TTK (gene)

    TTK_(gene)

  • IRAK4
  • Protein-coding gene in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    IRAK4

    IRAK4

    IRAK4

  • CHUK
  • Protein-coding gene in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    CHUK

    CHUK

    CHUK

  • PLK4
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    PLK4

    PLK4

    PLK4

  • MAP2K3
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MAP2K3

    MAP2K3

    MAP2K3

  • MAP3K3
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MAP3K3

    MAP3K3

    MAP3K3

  • PKMYT1
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    PKMYT1

    PKMYT1

    PKMYT1

  • SMG1
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    SMG1

    SMG1

    SMG1

  • SIK1
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    SIK1

    SIK1

    SIK1

  • Fox Chase Cancer Center
  • Cancer treatment and research institution in the US

    Philip Tsichlis, Alfonso Bellacosa, and Joseph Testa clone the AKT1 and AKT2 genes - the first viral oncogenes described that inhibit programmed cell

    Fox Chase Cancer Center

    Fox_Chase_Cancer_Center

  • KSR1
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    KSR1

    KSR1

    KSR1

  • Pleckstrin homology domain
  • Clinical Significance

    ABR, ADAP2, ADRBK1, ADRBK2, AFAP, AFAP1, AFAP1L1, AFAP1L2, AKAP13, AKT1, AKT2, AKT3, ANLN, APBB1IP, APPL1, APPL2, ARHGAP10, ARHGAP12, ARHGAP15, ARHGAP21

    Pleckstrin homology domain

    Pleckstrin homology domain

    Pleckstrin_homology_domain

  • GRK4
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    GRK4

    GRK4

    GRK4

  • Protein kinase A
  • Family of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • MTORC1
  • Protein complex

    mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes". Molecular Endocrinology

    MTORC1

    MTORC1

    MTORC1

  • Low-density-lipoprotein receptor kinase
  • Kinase enzyme involved in cholesterol homeostasis

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Low-density-lipoprotein receptor kinase

    Low-density-lipoprotein_receptor_kinase

  • Rho-associated protein kinase
  • Protein family

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Rho-associated protein kinase

    Rho-associated protein kinase

    Rho-associated_protein_kinase

  • BMPR1B
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    BMPR1B

    BMPR1B

    BMPR1B

  • Protein kinase C
  • Family of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Protein kinase C

    Protein_kinase_C

  • Serine/threonine-specific protein kinase
  • Class of protein kinase enzymes

    human akt genes exist. All three Akt kinases regulate cell proliferation and Akt2 is particularly important for insulin actions in cells. A major target of

    Serine/threonine-specific protein kinase

    Serine/threonine-specific protein kinase

    Serine/threonine-specific_protein_kinase

  • Phosphatidylinositol 3-kinase-related kinase
  • Protein family

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Phosphatidylinositol 3-kinase-related kinase

    Phosphatidylinositol_3-kinase-related_kinase

  • Wee1
  • Nuclear protein

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Wee1

    Wee1

    Wee1

  • MTOR inhibitors
  • Class of pharmaceutical drugs

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MTOR inhibitors

    MTOR inhibitors

    MTOR_inhibitors

  • RPS6KB2
  • Enzyme

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    RPS6KB2

    RPS6KB2

    RPS6KB2

  • MAP kinase kinase kinase kinase
  • Family of proteins

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MAP kinase kinase kinase kinase

    MAP_kinase_kinase_kinase_kinase

  • MAP3K11
  • Protein-coding gene in humans

    PMID 10490659. Figueroa C, Tarras S, Taylor J, Vojtek AB (November 2003). "Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex". J.

    MAP3K11

    MAP3K11

    MAP3K11

  • BRAF (gene)
  • Protein-coding gene in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • C-Jun N-terminal kinases
  • Chemical compounds

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    C-Jun N-terminal kinases

    C-Jun N-terminal kinases

    C-Jun_N-terminal_kinases

  • MAP kinase kinase kinase
  • Class of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MAP kinase kinase kinase

    MAP_kinase_kinase_kinase

  • Glucokinase
  • Enzyme participating to the regulation of carbohydrate metabolism

    6-bisphosphate (F2,6P 2) also stimulates GK transcription, it seems by way of Akt2 rather than SREBP1c. It is not known whether this effect is one of the downstream

    Glucokinase

    Glucokinase

    Glucokinase

  • Primary testicular diffuse large B-cell lymphoma
  • Medical condition

    stimulation of cellular proliferation and survival. 3) the genes for AKT1, AKT2, and PIK3CB, any one of which can lead to overactivation of the PI3K/AKT/mTOR

    Primary testicular diffuse large B-cell lymphoma

    Primary_testicular_diffuse_large_B-cell_lymphoma

  • ACVR1
  • Protein-coding gene

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    ACVR1

    ACVR1

    ACVR1

  • Aurora inhibitor
  • Putative drug class for treating cancer

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Aurora inhibitor

    Aurora inhibitor

    Aurora_inhibitor

  • MAP3K13
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MAP3K13

    MAP3K13

    MAP3K13

  • MASTL
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MASTL

    MASTL

    MASTL

  • DNA-PKcs
  • Protein found in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    DNA-PKcs

    DNA-PKcs

    DNA-PKcs

  • MTORC2
  • Protein complex

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MTORC2

    MTORC2

  • Fabiola Terzi
  • Italian-French scientist and physician

    fr. Retrieved 2021-05-15. Canaud, Guillaume; et al. (October 2013). "AKT2 is essential to maintain podocyte viability and function during chronic kidney

    Fabiola Terzi

    Fabiola_Terzi

  • APPL1
  • Protein-coding gene in the species Homo sapiens

    endosomes. APPL1 has been shown to interact with Deleted in Colorectal Cancer, AKT2, but also Rab5, Rab21, OCRL and almost 30 other proteins. GRCh38: Ensembl

    APPL1

    APPL1

    APPL1

  • Myosin light-chain kinase
  • Class of kinase enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Myosin light-chain kinase

    Myosin light-chain kinase

    Myosin_light-chain_kinase

  • Cyclin-dependent kinase
  • Class of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • GAK (protein)
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    GAK (protein)

    GAK (protein)

    GAK_(protein)

  • PIK3R4
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    PIK3R4

    PIK3R4

    PIK3R4

  • LIN28B
  • Protein-coding gene in the species Homo sapiens

    "RNA-binding protein LIN28B inhibits apoptosis through regulation of the AKT2/FOXO3A/BIM axis in ovarian cancer cells". Signal Transduction and Targeted

    LIN28B

    LIN28B

    LIN28B

  • Protein kinase C zeta type
  • Mammalian protein found in Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Protein kinase C zeta type

    Protein kinase C zeta type

    Protein_kinase_C_zeta_type

  • MAP3K12
  • Enzyme

    M006528200. PMID 10922377. Figueroa C, Tarras S, Taylor J, Vojtek AB (2004). "Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex". J.

    MAP3K12

    MAP3K12

    MAP3K12

  • VRK1
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    VRK1

    VRK1

    VRK1

  • Mitogen-activated protein kinase kinase
  • Kinase enzyme

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Mitogen-activated protein kinase kinase

    Mitogen-activated_protein_kinase_kinase

  • Ca2+/calmodulin-dependent protein kinase II
  • Class of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent_protein_kinase_II

  • IKBKG
  • Protein-coding gene in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    IKBKG

    IKBKG

    IKBKG

  • MAP3K9
  • Protein-coding gene in the species Homo sapiens

    PMC 139241. PMID 12477932. Figueroa C, Tarras S, Taylor J, Vojtek AB (2004). "Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex". J.

    MAP3K9

    MAP3K9

    MAP3K9

  • Extracellular signal-regulated kinases
  • Class of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Extracellular signal-regulated kinases

    Extracellular_signal-regulated_kinases

  • SH3RF1
  • Protein-coding gene in the species Homo sapiens

    of a functional signaling module. SH3RF1 has been shown to interact with AKT2 and MAP3K11. GRCh38: Ensembl release 89: ENSG00000154447 – Ensembl, May 2017

    SH3RF1

    SH3RF1

    SH3RF1

  • Acetate kinase
  • Class of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Acetate kinase

    Acetate kinase

    Acetate_kinase

  • ASK1
  • Protein found in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    ASK1

    ASK1

    ASK1

  • ATM serine/threonine kinase
  • Mammalian protein found in Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    ATM serine/threonine kinase

    ATM serine/threonine kinase

    ATM_serine/threonine_kinase

  • Phosphoinositide-dependent kinase-1
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent_kinase-1

  • Protein kinase R
  • Human protein and coding gene

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Protein kinase R

    Protein kinase R

    Protein_kinase_R

  • IRAK3
  • LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    IRAK3

    IRAK3

    IRAK3

  • CHEK2
  • Protein-coding gene in humans

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    CHEK2

    CHEK2

    CHEK2

  • Ataxia telangiectasia and Rad3 related
  • Protein kinase that detects DNA damage and halts cell division

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Ataxia telangiectasia and Rad3 related

    Ataxia telangiectasia and Rad3 related

    Ataxia_telangiectasia_and_Rad3_related

  • IKK2
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    IKK2

    IKK2

    IKK2

  • TGF beta receptor
  • Protein family

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    TGF beta receptor

    TGF_beta_receptor

  • Myotonin-protein kinase
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Myotonin-protein kinase

    Myotonin-protein kinase

    Myotonin-protein_kinase

  • Cyclin-dependent kinase 4
  • Human protein

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Cyclin-dependent kinase 4

    Cyclin-dependent kinase 4

    Cyclin-dependent_kinase_4

  • VRK2
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    VRK2

    VRK2

    VRK2

  • MAPK3
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    MAPK3

    MAPK3

    MAPK3

  • Pyruvate dehydrogenase kinase
  • Class of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Pyruvate dehydrogenase kinase

    Pyruvate dehydrogenase kinase

    Pyruvate_dehydrogenase_kinase

  • IkappaB kinase
  • Class of enzymes

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    IkappaB kinase

    IkappaB_kinase

  • Cyclin-dependent kinase 7
  • Protein-coding gene in the species Homo sapiens

    LATS2 MAST1 MAST2 STK38 STK38L CIT ROCK1 SGK SGK2 SGK3 Protein kinase B AKT1 AKT2 AKT3 Ataxia telangiectasia mutated mTOR EIF-2 kinases PKR HRI EIF2AK3 EIF2AK4

    Cyclin-dependent kinase 7

    Cyclin-dependent kinase 7

    Cyclin-dependent_kinase_7

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