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IKK2

  • IKK2

    • Protein-coding gene in the species Homo sapiens

    treatment of inflammatory diseases and cancer. The small-molecule inhibitor of IKK2 SAR113945, developed by Sanofi-Aventis, was evaluated in patients with knee

    IKK2

    IKK2

    IKK2

  • Hydroxyproline

    • Chemical compound

    targeting for proteasome degradation. DYRK1A, DYRK1B, protein kinase B, eEF2, IKK2, p53, FOXO3A, CEP192 are also reportedly hydroxylated by PHD1. p53 and MAPH6

    Hydroxyproline

    Hydroxyproline

    Hydroxyproline

  • NF-κB

    • Family of transcription factor protein complexes

    lymphoid organs. In contrast to the canonical signaling that relies on NEMO-IKK2 mediated degradation of IκBα, -β, -ε, non-canonical signaling depends on

    NF-κB

    NF-κB

    NF-κB

  • IkappaB kinase

    • Class of enzymes

    a separate gene: IKK-α (also known as IKK1) (CHUK) IKK-β (also known as IKK2) (IKBKB) IKK-γ (also known as NEMO) (IKBKG) The α- and β-subunits together

    IkappaB kinase

    IkappaB_kinase

  • SMG1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    SMG1

    SMG1

    SMG1

  • PKMYT1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PKMYT1

    PKMYT1

    PKMYT1

  • Titin

    • Largest known protein in human muscles

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Titin

    Titin

    Titin

  • Protein kinase B

    • Set of three serine threonine-specific protein kinases

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • MASTL

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MASTL

    MASTL

    MASTL

  • MAP3K14

    • Protein-coding gene in the species Homo sapiens

    interleukin-1 type-I receptor. MAP3K14 has been shown to interact with: CHUK, IKK2, and TRAF2. ENSG00000282637 GRCh38: Ensembl release 89: ENSG00000006062,

    MAP3K14

    MAP3K14

    MAP3K14

  • Rho-associated protein kinase

    • Protein family

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Rho-associated protein kinase

    Rho-associated protein kinase

    Rho-associated_protein_kinase

  • MAP kinase kinase kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAP kinase kinase kinase

    MAP_kinase_kinase_kinase

  • MTORC1

    • Protein complex

    alpha (TNF-alpha) can induce mTOR activity through IKK beta, also known as IKK2. IKK beta can phosphorylate TSC1 at serine residue 487 and TSC1 at serine

    MTORC1

    MTORC1

    MTORC1

  • Specialized pro-resolving mediators

    • Cellular molecules that help resolve inflammation

    reactions. PUFA-cyclopentenones may likewise react with the IKK2 component of the cytosolic IKK2-NFκB protein complex thereby inhibiting NFκB from stimulating

    Specialized pro-resolving mediators

    Specialized_pro-resolving_mediators

  • AMP-activated protein kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • Mitogen-activated protein kinase

    • P38 mitogen-activated protein kinases

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Mitogen-activated protein kinase

    Mitogen-activated_protein_kinase

  • Aurora kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Aurora kinase

    Aurora_kinase

  • IκBα

    • Protein-coding gene in the species Homo sapiens

    C22orf25, CHUK, DYNLL1, G3BP2, Heterogeneous nuclear ribonucleoprotein A1, IKK2, NFKB1, P53, RELA, RPS6KA1, SUMO4, and Valosin-containing protein. GRCh38:

    IκBα

    IκBα

    IκBα

  • RELB

    • Protein-coding gene in the species Homo sapiens

    the non-canonical pathway, viz RelB and p52, are controlled by canonical IKK2-IκB-RelA:p50 signalling. Moreover, generation of canonical and non-canonical

    RELB

    RELB

    RELB

  • Tumor necrosis factor receptor 1

    • Membrane receptor protein found in humans

    dementia. TNFRSF1A has been shown to interact with: BAG4, CASP10, FADD, IKK2, JAK1, JAK2, PIP4K2B, PSMD2, RIPK1, SUMO1, TRADD TRAF2, TRPC4AP, TNF, and

    Tumor necrosis factor receptor 1

    Tumor necrosis factor receptor 1

    Tumor_necrosis_factor_receptor_1

  • Cyclin-dependent kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • Protein kinase C

    • Family of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase C

    Protein_kinase_C

  • Akt/PKB signaling pathway

    • Series of biochemical reactions

    promote insulin resistance in response to TNF-(alpha) signaling through IKK2". J Biol Chem. 283 (51): 35375–82. doi:10.1074/jbc.M806480200. PMC 2602883

    Akt/PKB signaling pathway

    Akt/PKB_signaling_pathway

  • GSK3A

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    GSK3A

    GSK3A

    GSK3A

  • KSR2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    KSR2

    KSR2

    KSR2

  • DNA-PKcs

    • Protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    DNA-PKcs

    DNA-PKcs

    DNA-PKcs

  • TRIB2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    TRIB2

    TRIB2

    TRIB2

  • MTOR

    • Mammalian protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MTOR

    MTOR

    MTOR

  • Extracellular signal-regulated kinases

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Extracellular signal-regulated kinases

    Extracellular_signal-regulated_kinases

  • BRAF (gene)

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • BCKDK

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    BCKDK

    BCKDK

    BCKDK

  • PRKY

    • Pseudogene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PRKY

    PRKY

    PRKY

  • CAMK2B

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    CAMK2B

    CAMK2B

    CAMK2B

  • PRKG1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PRKG1

    PRKG1

    PRKG1

  • IRAK3

    • Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    IRAK3

    IRAK3

    IRAK3

  • Phosphatidylinositol 3-kinase-related kinase

    • Protein family

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Phosphatidylinositol 3-kinase-related kinase

    Phosphatidylinositol_3-kinase-related_kinase

  • MAPK3

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAPK3

    MAPK3

    MAPK3

  • Protein kinase A

    • Family of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • MYLK4

    • Enzyme in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MYLK4

    MYLK4

    MYLK4

  • PRKAG2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PRKAG2

    PRKAG2

    PRKAG2

  • IKBKG

    • Protein-coding gene in humans

    injection. IKBKG has been shown to interact with: BCL10, CDC37, CHUK and IKK2, IRAK1, NCOA3, PPM1B, TANK, TNFAIP3, TRAF3IP2, and TRAF6. GRCh38: Ensembl

    IKBKG

    IKBKG

    IKBKG

  • PHKB

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PHKB

    PHKB

    PHKB

  • Imd pathway

    • Immune signaling pathway of insects

    orthologue = FADD Key/Ikkγ: human orthologue = NEMO Ird5: human orthologue = IKK2 Relish: human orthologues = p65/p50 and IκB Iap2: human orthologue = cIAP2

    Imd pathway

    Imd pathway

    Imd_pathway

  • Tropomyosin kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Tropomyosin kinase

    Tropomyosin_kinase

  • ASK1

    • Protein found in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    ASK1

    ASK1

    ASK1

  • P70-S6 Kinase 1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • VRK2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    VRK2

    VRK2

    VRK2

  • Goodpasture-antigen-binding protein kinase

    • Phosphate-transferring enzyme

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Goodpasture-antigen-binding protein kinase

    Goodpasture-antigen-binding_protein_kinase

  • ACVR1

    • Protein-coding gene

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    ACVR1

    ACVR1

    ACVR1

  • GSK-3

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    GSK-3

    GSK-3

    GSK-3

  • BMPR1A

    • Bone morphogenetic protein receptor

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    BMPR1A

    BMPR1A

    BMPR1A

  • Aurora inhibitor

    • Putative drug class for treating cancer

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Aurora inhibitor

    Aurora inhibitor

    Aurora_inhibitor

  • P38 mitogen-activated protein kinases

    • Protein family

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    P38 mitogen-activated protein kinases

    P38_mitogen-activated_protein_kinases

  • AKT1

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    AKT1

    AKT1

    AKT1

  • VRK1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    VRK1

    VRK1

    VRK1

  • Cellular neuroscience

    • Branch of neuroscience

    microdomains Cell biology Cell signaling Chemical synapse Dendrite Hair cells IKK2 Neuroendocrinology Neuropharmacology Pyramidal cells Soliton model Synaptotropic

    Cellular neuroscience

    Cellular_neuroscience

  • CCG-4986

    • Chemical compound

    KS (May 2008). "Interleukin-1beta up-regulates RGS4 through the canonical IKK2/IkappaBalpha/NF-kappaB pathway in rabbit colonic smooth muscle". The Biochemical

    CCG-4986

    CCG-4986

    CCG-4986

  • Wee1

    • Nuclear protein

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Wee1

    Wee1

    Wee1

  • Phosphoinositide-dependent kinase-1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent_kinase-1

  • GAK (protein)

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    GAK (protein)

    GAK (protein)

    GAK_(protein)

  • NLK

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    NLK

    NLK

    NLK

  • C-Jun N-terminal kinases

    • Chemical compounds

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    C-Jun N-terminal kinases

    C-Jun N-terminal kinases

    C-Jun_N-terminal_kinases

  • CGMP-dependent protein kinase

    • Protein kinase

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    CGMP-dependent protein kinase

    CGMP-dependent protein kinase

    CGMP-dependent_protein_kinase

  • CAMK

    • Enzyme type

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    CAMK

    CAMK

  • MAP kinase kinase kinase kinase

    • Family of proteins

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAP kinase kinase kinase kinase

    MAP_kinase_kinase_kinase_kinase

  • CHUK

    • Protein-coding gene in humans

    IKK-α has been shown to interact with: HDAC9, AKT1, CTNNB1, FANCA, IKBKG IKK2, IRAK1, MAP3K14, MAP3K7, MAP3K8, NFKBIA, NCOA3, PPM1B, PRKDC, and TRAF2.

    CHUK

    CHUK

    CHUK

  • Phototropin

    • Class of photoreceptor proteins in plants

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Phototropin

    Phototropin

  • Cyclin-dependent kinase 1

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Cyclin-dependent kinase 1

    Cyclin-dependent kinase 1

    Cyclin-dependent_kinase_1

  • Catenin beta-1

    • Mammalian protein found in humans

    CDK5R1, CHUK, CTNND1, CTNNA1, EGFR, Emerin ESR1 FHL2, GSK3B, HER2/neu, HNF4A, IKK2, LEF1 including transgenically, MAGI1, MUC1, NR5A1, PCAF, PHF17, Plakoglobin

    Catenin beta-1

    Catenin beta-1

    Catenin_beta-1

  • RAF kinase

    • Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    RAF kinase

    RAF kinase

    RAF_kinase

  • Myosin light-chain kinase

    • Class of kinase enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Myosin light-chain kinase

    Myosin light-chain kinase

    Myosin_light-chain_kinase

  • Mitogen-activated protein kinase kinase

    • Kinase enzyme

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Mitogen-activated protein kinase kinase

    Mitogen-activated_protein_kinase_kinase

  • Serine/threonine-specific protein kinase

    • Class of protein kinase enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Serine/threonine-specific protein kinase

    Serine/threonine-specific protein kinase

    Serine/threonine-specific_protein_kinase

  • MTORC2

    • Protein complex

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MTORC2

    MTORC2

  • Protein kinase R

    • Human protein and coding gene

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase R

    Protein kinase R

    Protein_kinase_R

  • PIK3R4

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PIK3R4

    PIK3R4

    PIK3R4

  • Nuclear receptor coactivator 3

    • Protein found in humans

    receptor alpha, Estrogen receptor beta, Glucocorticoid receptor, IKBKG, IKK2, Retinoid X receptor alpha. Nuclear Factor Kappa B, GRCh38: Ensembl release

    Nuclear receptor coactivator 3

    Nuclear receptor coactivator 3

    Nuclear_receptor_coactivator_3

  • RELA

    • Protein-coding gene in the species Homo sapiens

    to targeted phosphorylation of RELA by different kinases. For instance, IKK2 is found to be mainly responsible for phosphorylating serine 536 in monocytes

    RELA

    RELA

    RELA

  • Aurora kinase A

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Aurora kinase A

    Aurora kinase A

    Aurora_kinase_A

  • Protein kinase C zeta type

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Protein kinase C zeta type

    Protein kinase C zeta type

    Protein_kinase_C_zeta_type

  • MTOR inhibitors

    • Class of pharmaceutical drugs

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MTOR inhibitors

    MTOR inhibitors

    MTOR_inhibitors

  • PPM1B

    • Protein-coding gene in the species Homo sapiens

    sequences. PPM1B has been shown to interact with: CDK2, CDK6, CHUK, IKBKG, IKK2, MAP3K7, and PPARγ. GRCh38: Ensembl release 89: ENSG00000138032 – Ensembl

    PPM1B

    PPM1B

    PPM1B

  • Pyruvate dehydrogenase kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Pyruvate dehydrogenase kinase

    Pyruvate dehydrogenase kinase

    Pyruvate_dehydrogenase_kinase

  • Ribosomal s6 kinase

    • Family of protein kinases

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Ribosomal s6 kinase

    Ribosomal s6 kinase

    Ribosomal_s6_kinase

  • PLK1

    • Mammalian protein found in Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    PLK1

    PLK1

    PLK1

  • CDC37

    • Protein-coding gene in humans

    target kinases. CDC37 has been shown to interact with: CDK4, HSP90AA1 IKBKG, IKK2, and STK11. CDC37 consists of three structural domains. The N-terminal domain

    CDC37

    CDC37

    CDC37

  • HDAC9

    • Protein-coding gene in the species Homo sapiens

    genes by motor innervation. HDAC9 has been shown to interact with: IKK1, IKK2, CBX5, HDAC3, BTG2, Myocyte-specific enhancer factor 2A Nuclear receptor

    HDAC9

    HDAC9

    HDAC9

  • Ca2+/calmodulin-dependent protein kinase II

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent_protein_kinase_II

  • CDKL5

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    CDKL5

    CDKL5

    CDKL5

  • Acetate kinase

    • Class of enzymes

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Acetate kinase

    Acetate kinase

    Acetate_kinase

  • G protein-coupled receptor kinase 2

    • Enzyme

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    G protein-coupled receptor kinase 2

    G protein-coupled receptor kinase 2

    G_protein-coupled_receptor_kinase_2

  • MAPK1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAPK1

    MAPK1

    MAPK1

  • Phosphorylase kinase

    • Enzyme involved in glycogenolysis

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Phosphorylase kinase

    Phosphorylase kinase

    Phosphorylase_kinase

  • MYLK2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MYLK2

    MYLK2

    MYLK2

  • Aurora kinase B

    • Protein

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    Aurora kinase B

    Aurora kinase B

    Aurora_kinase_B

  • CHEK1

    • Protein-coding gene in humans

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    CHEK1

    CHEK1

    CHEK1

  • TRAF2

    • Protein-coding gene in humans

    CASP8AP2, CD134, CD137, CD27, CD40, CFLAR, CHUK, Caveolin 1, EDARADD, HIVEP3, IKK2, Low affinity nerve growth factor receptor, MAP3K14, MAP3K1, MAP3K7IP2, MAP4K2

    TRAF2

    TRAF2

    TRAF2

  • IRAK1

    • Protein-coding gene in humans

    IRAK1 has been shown to interact with the following proteins: CHUK IKBKG IKK2, Myd88 NEMO SOCS1 STAT3 TRAF6 UBC, TOLLIP TLR4 IRAK-1 signaling is involved

    IRAK1

    IRAK1

    IRAK1

  • BMPR2

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    BMPR2

    BMPR2

    BMPR2

  • MAP2K1

    • Protein-coding gene in the species Homo sapiens

    Goodpasture-antigen-binding protein kinase (EC 2.7.11.9) - IκB kinase (EC 2.7.11.10) CHUK IKK2 TBK1 IKBKE IKBKG IKBKAP cAMP-dependent protein kinase (EC 2.7.11.11) Protein

    MAP2K1

    MAP2K1

    MAP2K1

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