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ACVR1

  • ACVR1

    • Protein-coding gene

    type I (ACVR1) is a protein which in humans is encoded by the ACVR1 gene; it is also known as ALK-2 (activin receptor-like kinase-2). ACVR1 has been

    ACVR1

    ACVR1

    ACVR1

  • Fibrodysplasia ossificans progressiva

    • Disease in which fibrous connective tissue turns into bone

    the nickname "stone man disease". FOP is caused by a mutation of the gene ACVR1, affecting the body's repair mechanism. Fibrous tissue including muscle

    Fibrodysplasia ossificans progressiva

    Fibrodysplasia ossificans progressiva

    Fibrodysplasia_ossificans_progressiva

  • Activin and inhibin

    • Regulators of feedback on FSH-production

    kinase activities in their cytoplasmic domains: Activin type 1 receptors: ACVR1, ACVR1B, ACVR1C Activin type 2 receptors: ACVR2A, ACVR2B Activin binds to

    Activin and inhibin

    Activin and inhibin

    Activin_and_inhibin

  • Harry Raymond Eastlack

    • American medical patient (1933–1973)

    able to distinguish the particular gene responsible for the disease, the ACVR1 gene. It is said that Eastlack's skeleton was a useful reference for this

    Harry Raymond Eastlack

    Harry Raymond Eastlack

    Harry_Raymond_Eastlack

  • Bone morphogenetic protein receptor

    • Group of three receptors to bone morphogenetic proteins

    morphogenetic protein receptors: Bone morphogenetic protein receptor, type 1: ACVR1 BMPR1A BMPR1B Bone morphogenetic protein receptor, type 2 Both type 1 and

    Bone morphogenetic protein receptor

    Bone_morphogenetic_protein_receptor

  • Perelman School of Medicine

    • Medical school in Philadelphia, Pennsylvania, US

    Shore, EM (May 2006). "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva". Nature

    Perelman School of Medicine

    Perelman School of Medicine

    Perelman_School_of_Medicine

  • All-points bulletin

    • Police broadcast

    his team were in fact able to identify the gene responsible, known as the ACVR1 mutation. This would go on to allow deeper research about the disease, and

    All-points bulletin

    All-points bulletin

    All-points_bulletin

  • Paramesonephric duct

    • Paired ducts in the mammalian embryo in the primitive urogenital structures

    activation of AMHR2 causes the expression of "type 1" receptors, which include ACVR1 (ALK2), BMPR1A (ALK3), or BMPR1B (ALK6). Both types I and II are required

    Paramesonephric duct

    Paramesonephric duct

    Paramesonephric_duct

  • Frederick Kaplan

    • American medical researcher

    publishing their findings as "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva". The

    Frederick Kaplan

    Frederick Kaplan

    Frederick_Kaplan

  • Palovarotene

    • Chemical compound

    fibrodysplasia ossificans progressiva containing a continuously active ACVR1/ALK2 receptor in a dose-dependent manner. A 2016 study demonstrated that

    Palovarotene

    Palovarotene

    Palovarotene

  • Eileen Shore

    • American medical researcher

    FOP as a paper entitled "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva". The

    Eileen Shore

    Eileen Shore

    Eileen_Shore

  • Mitogen-activated protein kinase

    • P38 mitogen-activated protein kinases

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Mitogen-activated protein kinase

    Mitogen-activated_protein_kinase

  • Chromosome 4

    • Human chromosome

    the infobox on the right. AASDH: aminoadipate-semialdehyde dehydrogenase ACVR1: activin-like kinase 2 (ALK-2) ACOX3: encoding enzyme Peroxisomal acyl-coenzyme

    Chromosome 4

    Chromosome 4

    Chromosome_4

  • List of genes mutated in cutaneous conditions

    • glycoprotein ABCC6 Pseudoxanthoma elasticum ABCC7 CFTR protein Cystic fibrosis ACVR1 Fibrodysplasia ossificans progressiva ACVRL1 (ALK1) Activin A Hereditary

    List of genes mutated in cutaneous conditions

    List_of_genes_mutated_in_cutaneous_conditions

  • List of investigational hair loss drugs

    • Investigational hair loss drugs

    of action Gecaxitinib (gecacitinib, jaktinib) – oral – alopecia areata – ACVR1 protein inhibitor, Janus kinase 1 inhibitor, Janus kinase 2 inhibitor, Janus

    List of investigational hair loss drugs

    List_of_investigational_hair_loss_drugs

  • Titin

    • Largest known protein in human muscles

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Titin

    Titin

    Titin

  • FOP Friends

    • the FOP gene on the human chromosomes. The gene, a BMP receptor termed ACVR1, was mapped to chromosome 2 and more precisely to a small region between

    FOP Friends

    FOP Friends

    FOP_Friends

  • Wee1

    • Nuclear protein

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Wee1

    Wee1

    Wee1

  • Michael Zasloff

    • American physician–scientist and immunologist

    Frederick S. (2006). "A recurrent mutation in the BMP type I receptor ACVR1 causes fibrodysplasia ossificans progressiva". Nature Genetics. 38 (5):

    Michael Zasloff

    Michael Zasloff

    Michael_Zasloff

  • Spontaneous coronary artery dissection

    • Uncommon cause of heart attacks mostly affecting younger, healthy women

    metabolism. Variants in genes including ALDH18A1, COL3A1, COL4A1, FBN1 and ACVR1 were implicated in a study of 91 unrelated SCAD cases. Given the demographics

    Spontaneous coronary artery dissection

    Spontaneous coronary artery dissection

    Spontaneous_coronary_artery_dissection

  • Heterotopic ossification

    • Formation of bone tissue outside of the skeleton

    Fibrodysplasia ossificans progressiva (FOP), which is caused by a mutation in the ACVR1 gene, or Progressive osseous heteroplasia (POH), which is caused by a mutational

    Heterotopic ossification

    Heterotopic ossification

    Heterotopic_ossification

  • AMP-activated protein kinase

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • Bone morphogenetic protein receptor, type 1

    • Group of type I transmembrane proteins

    bone morphogenetic proteins. The three types of type I BMP receptors are ACVR1, BMPR1A and BMPR1B. Bone+Morphogenetic+Protein+Receptors,+Type+I at the

    Bone morphogenetic protein receptor, type 1

    Bone_morphogenetic_protein_receptor,_type_1

  • Dephospho-(reductase kinase) kinase

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Dephospho-(reductase kinase) kinase

    Dephospho-(reductase_kinase)_kinase

  • Myotonin-protein kinase

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Myotonin-protein kinase

    Myotonin-protein kinase

    Myotonin-protein_kinase

  • BRSK2

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    BRSK2

    BRSK2

    BRSK2

  • BCKDHA

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    BCKDHA

    BCKDHA

    BCKDHA

  • MAP2K7

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MAP2K7

    MAP2K7

    MAP2K7

  • Cyclin-dependent kinase

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • MAP2K2

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MAP2K2

    MAP2K2

    MAP2K2

  • Phosphatidylinositol 3-kinase-related kinase

    • Protein family

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Phosphatidylinositol 3-kinase-related kinase

    Phosphatidylinositol_3-kinase-related_kinase

  • Activin receptor

    • Protein domain

    domain. Types include: Activin type 1 receptors Activin type 2 receptors ACVR1; ACVR1B; ACVR1C; ACVR2A; ACVR2B; ACVRL1; BMPR1A; BMPR1B; BMPR2; TGFBR1;

    Activin receptor

    Activin_receptor

  • Housekeeping gene

    • Gene which maintains basic cellular functions

    SLC39A7 NM_006979 SLC41A3 NM_017836 SLC46A3 NM_181785 SLC48A1 NM_017842 ACVR1 NM_001105 similar to ACVRL1 TGF Beta receptor family Rendu-Osler-Weber syndrome

    Housekeeping gene

    Housekeeping_gene

  • Extracellular signal-regulated kinases

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Extracellular signal-regulated kinases

    Extracellular_signal-regulated_kinases

  • Protein kinase B

    • Set of three serine threonine-specific protein kinases

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • MAP3K12

    • Enzyme

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MAP3K12

    MAP3K12

    MAP3K12

  • PRKD3

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    PRKD3

    PRKD3

    PRKD3

  • P70-S6 Kinase 1

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • Serine/threonine-specific protein kinase

    • Class of protein kinase enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Serine/threonine-specific protein kinase

    Serine/threonine-specific protein kinase

    Serine/threonine-specific_protein_kinase

  • PRKAB2

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    PRKAB2

    PRKAB2

    PRKAB2

  • DAPK3

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    DAPK3

    DAPK3

    DAPK3

  • TRIO (gene)

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    TRIO (gene)

    TRIO (gene)

    TRIO_(gene)

  • Phosphorylase kinase

    • Enzyme involved in glycogenolysis

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Phosphorylase kinase

    Phosphorylase kinase

    Phosphorylase_kinase

  • PRKAG3

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    PRKAG3

    PRKAG3

    PRKAG3

  • Cyclin-dependent kinase 2

    • Protein found in humans

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Cyclin-dependent kinase 2

    Cyclin-dependent kinase 2

    Cyclin-dependent_kinase_2

  • Aurora inhibitor

    • Putative drug class for treating cancer

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Aurora inhibitor

    Aurora inhibitor

    Aurora_inhibitor

  • EIF2AK4

    • Protein-coding gene in humans

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    EIF2AK4

    EIF2AK4

    EIF2AK4

  • BMPR1A

    • Bone morphogenetic protein receptor

    BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF beta superfamily

    BMPR1A

    BMPR1A

    BMPR1A

  • GAK (protein)

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    GAK (protein)

    GAK (protein)

    GAK_(protein)

  • STK11

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    STK11

    STK11

    STK11

  • Protein kinase C

    • Family of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Protein kinase C

    Protein_kinase_C

  • PIK3R4

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    PIK3R4

    PIK3R4

    PIK3R4

  • Ca2+/calmodulin-dependent protein kinase II

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent_protein_kinase_II

  • Hereditary hemorrhagic telangiectasia

    • Genetic disorder affecting blood vessel development

    surface of the cell). HHT2 600376 ACVRL1 12q11-q14 ACVRL1 codes for Alk-1 (ACVR1, activin receptor-like kinase 1), a TGF-β1 receptor; genetic linkage was

    Hereditary hemorrhagic telangiectasia

    Hereditary hemorrhagic telangiectasia

    Hereditary_hemorrhagic_telangiectasia

  • C-Jun N-terminal kinases

    • Chemical compounds

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    C-Jun N-terminal kinases

    C-Jun N-terminal kinases

    C-Jun_N-terminal_kinases

  • Tau-protein kinase

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Tau-protein kinase

    Tau-protein kinase

    Tau-protein_kinase

  • P38 mitogen-activated protein kinases

    • Protein family

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    P38 mitogen-activated protein kinases

    P38_mitogen-activated_protein_kinases

  • GDF2

    • Protein-coding gene in the species Homo sapiens

    with a lower affinity ALK2, also known has Activin A receptor, type I (ACVR1), and the other type II receptors BMPRII and ActRIIA. GDF2 and BMP10 are

    GDF2

    GDF2

    GDF2

  • ATM serine/threonine kinase

    • Mammalian protein found in Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    ATM serine/threonine kinase

    ATM serine/threonine kinase

    ATM_serine/threonine_kinase

  • MTOR

    • Mammalian protein found in humans

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MTOR

    MTOR

    MTOR

  • MAP kinase kinase kinase kinase

    • Family of proteins

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MAP kinase kinase kinase kinase

    MAP_kinase_kinase_kinase_kinase

  • H3F3A

    • Gene for histone H3.3 protein

    pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations". Nature Genetics. 46 (5): 451–6. doi:10.1038/ng.2936. PMC 3997489

    H3F3A

    H3F3A

    H3F3A

  • PKMYT1

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    PKMYT1

    PKMYT1

    PKMYT1

  • Mitogen-activated protein kinase kinase

    • Kinase enzyme

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Mitogen-activated protein kinase kinase

    Mitogen-activated_protein_kinase_kinase

  • Phototropin

    • Class of photoreceptor proteins in plants

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Phototropin

    Phototropin

  • SMG1

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    SMG1

    SMG1

    SMG1

  • WNK4

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    WNK4

    WNK4

    WNK4

  • IkappaB kinase

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    IkappaB kinase

    IkappaB_kinase

  • Rho-associated protein kinase

    • Protein family

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Rho-associated protein kinase

    Rho-associated protein kinase

    Rho-associated_protein_kinase

  • G protein-coupled receptor kinase

    • Family of protein kinases

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    G protein-coupled receptor kinase

    G protein-coupled receptor kinase

    G_protein-coupled_receptor_kinase

  • CAMK

    • Enzyme type

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    CAMK

    CAMK

  • Protein kinase A

    • Family of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • MYLK2

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MYLK2

    MYLK2

    MYLK2

  • Protein kinase R

    • Human protein and coding gene

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Protein kinase R

    Protein kinase R

    Protein_kinase_R

  • TGF beta receptor

    • Protein family

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    TGF beta receptor

    TGF_beta_receptor

  • Activin type 1 receptors

    • Human biological material

    apoptosis and many other functions. There are three type I Activin receptors: ACVR1, ACVR1B, and ACVR1C. Each bind to a specific type II receptor-ligand complex

    Activin type 1 receptors

    Activin_type_1_receptors

  • NLK

    • Mammalian protein found in Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    NLK

    NLK

    NLK

  • MAP kinase kinase kinase

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MAP kinase kinase kinase

    MAP_kinase_kinase_kinase

  • Aurora kinase A

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Aurora kinase A

    Aurora kinase A

    Aurora_kinase_A

  • MTOR inhibitors

    • Class of pharmaceutical drugs

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MTOR inhibitors

    MTOR inhibitors

    MTOR_inhibitors

  • Protein kinase C zeta type

    • Mammalian protein found in Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Protein kinase C zeta type

    Protein kinase C zeta type

    Protein_kinase_C_zeta_type

  • Protein kinase domain

    • Protein domain

    proteins containing the protein kinase domain: AAK1 ; AATK ; ABL1 ; ABL2 ; ACVR1 ; ACVR1B ; ACVR1C ; ACVR2A ; ACVR2B ; ACVRL1 ; AKT1 ; AKT2 ; AKT3 ; ALK ;

    Protein kinase domain

    Protein kinase domain

    Protein_kinase_domain

  • International FOP Association

    • American organization

    Frederick S. (2006). "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva". Nature

    International FOP Association

    International_FOP_Association

  • IKBKG

    • Protein-coding gene in humans

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    IKBKG

    IKBKG

    IKBKG

  • 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase

    • Class of enzymes

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase

    3-methyl-2-oxobutanoate_dehydrogenase_(acetyl-transferring)_kinase

  • Protein kinase D1

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Protein kinase D1

    Protein kinase D1

    Protein_kinase_D1

  • PRKACA

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    PRKACA

    PRKACA

    PRKACA

  • VRK2

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    VRK2

    VRK2

    VRK2

  • G protein-coupled receptor kinase 3

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    G protein-coupled receptor kinase 3

    G protein-coupled receptor kinase 3

    G_protein-coupled_receptor_kinase_3

  • MTORC1

    • Protein complex

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MTORC1

    MTORC1

    MTORC1

  • MAPK1

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MAPK1

    MAPK1

    MAPK1

  • WNK3

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    WNK3

    WNK3

    WNK3

  • Phosphoinositide-dependent kinase-1

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent kinase-1

    Phosphoinositide-dependent_kinase-1

  • Casein kinase 1, alpha 1

    • Enzyme found in humans

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    Casein kinase 1, alpha 1

    Casein kinase 1, alpha 1

    Casein_kinase_1,_alpha_1

  • BMPR2

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    BMPR2

    BMPR2

    BMPR2

  • MASTL

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MASTL

    MASTL

    MASTL

  • RAF kinase

    • 7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    RAF kinase

    RAF kinase

    RAF_kinase

  • MKNK2

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MKNK2

    MKNK2

    MKNK2

  • PKC alpha

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    PKC alpha

    PKC alpha

    PKC_alpha

  • MAP2K6

    • Protein-coding gene in the species Homo sapiens

    7.11.30) Bone morphogenetic protein receptors BMPR1 BMPR1A BMPR1B BMPR2 ACVR1 ACVR1B ACVR1C ACVR2A ACVR2B ACVRL1 Anti-Müllerian hormone receptor Dual-specificity

    MAP2K6

    MAP2K6

    MAP2K6

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Online names & meanings

  • Meg

    • Girl/Female

    Greek American Persian

    Meg

    Pearl.

  • Tedric

    • Boy/Male

    English

    Tedric

    Abbreviation of Theodore.

  • Bhupal

    • Boy/Male

    Assamese, Gujarati, Hindu, Indian, Jain, Kannada, Malayalam, Marathi, Sanskrit, Telugu

    Bhupal

    King

  • Verdaan

    • Boy/Male

    Hindu

    Verdaan

    Ver

  • Ixion

    • Boy/Male

    Greek

    Ixion

    Father of the centaurs.

  • Urna | அர்நா

    • Girl/Female

    Tamil

    Urna | அர்நா

    Cover

  • Aubrey

    • Boy/Male

    English American French Teutonic

    Aubrey

    Rules with elf-wisdom. Introduced into Britain from France by Aubrey de Vere, a friend of William...

  • Avin

    • Boy/Male

    Hindu

    Avin

    Beauty, Son of Ashim

  • NIKÊ

    • Female

    Greek

    NIKÊ

    (Νίκη) Greek name NIKÊ means "victory." In mythology, this is the name of a goddess of victory.

  • Mahfooza

    • Girl/Female

    Arabic, Muslim

    Mahfooza

    Safeguarded; Well-protected; Feminine of Mahfooz

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