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PHLPP

  • PHLPP
  • Class of enzymes

    The PHLPP isoforms (PH domain and Leucine rich repeat Protein Phosphatases) are a pair of protein phosphatases, PHLPP1 and PHLPP2, that are important

    PHLPP

    PHLPP

  • PHLPP (gene)
  • Protein-coding gene in the species Homo sapiens

    repeat protein phosphatase, also known as PHLPP, is an enzyme which in humans is encoded by the PHLPP gene. PHLPP GRCh38: Ensembl release 89: ENSG00000081913

    PHLPP (gene)

    PHLPP (gene)

    PHLPP_(gene)

  • FKBP5
  • Protein-coding gene in humans

    helping AKT interact with PHLPP, which dephosphorylates AKT at Ser473. FKBP5 binds to AKT through its FK1 domain and to PHLPP through its TPR domain, supporting

    FKBP5

    FKBP5

    FKBP5

  • Protein kinase B
  • Set of three serine threonine-specific protein kinases

    phosphatases dephosphorylate PIP3 to form PIP2. The phosphatases in the PHLPP family, PHLPP1 and PHLPP2 have been shown to directly de-phosphorylate,

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • PHLPPL
  • Protein-coding gene in the species Homo sapiens

    as PHLPPL, is an enzyme which in humans is encoded by the PHLPPL gene. PHLPP GRCh38: Ensembl release 89: ENSG00000040199 – Ensembl, May 2017 GRCm38:

    PHLPPL

    PHLPPL

    PHLPPL

  • Alexandra Newton
  • US-based Protein Kinase C expert

    important discoveries in the protein phosphatase field, discovering and naming PHLPP (PH domain and Leucine rich repeat Protein Phosphatases), which regulate

    Alexandra Newton

    Alexandra Newton

    Alexandra_Newton

  • Pleckstrin homology domain
  • Clinical Significance

    OSBPL5, OSBPL6, OSBPL7, OSBPL8, OSBPL9, PHLDA2, PHLDA3, PHLDB1, PHLDB2, PHLPP, PIP3-E, PLCD1, PLCD4, PLCG1, PLCG2, PLCH1, PLCH2, PLCL1, PLCL2, PLD1, PLD2

    Pleckstrin homology domain

    Pleckstrin homology domain

    Pleckstrin_homology_domain

  • Akt/PKB signaling pathway
  • Series of biochemical reactions

    phosphatase 2A (PP2A), which dephosphorylates Akt at Thr308 and phosphatase PHLPP dephosphorylates Akt at Ser473. Another protein important in Akt attenuation

    Akt/PKB signaling pathway

    Akt/PKB_signaling_pathway

  • Mir-190 microRNA precursor family
  • Short RNA molecule

    Castranova V, Shi X, Chen F (October 2011). "miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis". Toxicological

    Mir-190 microRNA precursor family

    Mir-190_microRNA_precursor_family

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PHLPP

Online names & meanings

  • Bhagyashree
  • Girl/Female

    Indian

    Bhagyashree

    Goddess Lakshmi, Lucky

  • Razil
  • Boy/Male

    Arabic

    Razil

    Beauty

  • Bahar
  • Girl/Female

    Afghan, Arabic, German, Hindu, Indian, Iranian, Muslim, Parsi, Sindhi, Turkish

    Bahar

    Spring Season; Prime of Life; Bloom of Youth

  • Mansoorah
  • Boy/Male

    Arabic, Muslim

    Mansoorah

    Protected; Victorious; Triumphant; Defended; Conquering; Aided; Succoured

  • Apps
  • Surname or Lastname

    English (Kent)

    Apps

    English (Kent) : from Middle English apse ‘aspen tree’ (Old English æpse). See also Asp. Generally, this was a topographic name for someone who lived by an aspen or a habitational name from a place named with this word, as for example Apps in Surrey, Apse on the Isle of Wight, or Asps in Warwickshire. Occasionally it may have been applied as a nickname for a timorous person, with reference to the trembling leaves.Dutch : variant of Epps.

  • Sushama | ஸுஷமா
  • Girl/Female

    Tamil

    Sushama | ஸுஷமா

    Beautiful woman

  • Trinity
  • Girl/Female

    Hindu

    Trinity

    Three, Triple

  • Jeruel
  • Biblical

    Jeruel

    fear, or vision of God

  • Caelan
  • Boy/Male

    Gaelic Irish

    Caelan

    Contemporary'Child.

  • NGO-KWANG
  • Female

    Chinese

    NGO-KWANG

    beauty-august.

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PHLPP

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PHLPP