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PLK4

  • PLK4

    • Protein-coding gene in the species Homo sapiens

    Serine/threonine-protein kinase PLK4 also known as polo-like kinase 4 is an enzyme that in humans is encoded by the PLK4 gene. The Drosophila homolog is

    PLK4

    PLK4

    PLK4

  • David Glover (geneticist)

    • British geneticist

    (Plk4) is its master regulator; Plk4 expression can drive the de novo formation of centrioles in unfertilised Drosophila eggs. In searching for Plk4's

    David Glover (geneticist)

    David_Glover_(geneticist)

  • STIL

    • Protein-coding gene in the species Homo sapiens

    premature neural differentiation, whereas PLK4 overexpression in environment induces skin cancer. As a PLK4 downstream effector, STIL may possibly indirectly

    STIL

    STIL

    STIL

  • Chromosome 4

    • Human chromosome

    dominant) PLAC8: encoding protein Placenta specific 8 PLK4: Serine/threonine-protein kinase PLK4 PPEF2: encoding protein Protein phosphatase with ef-hand

    Chromosome 4

    Chromosome 4

    Chromosome_4

  • AMP-activated protein kinase

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    AMP-activated protein kinase

    AMP-activated protein kinase

    AMP-activated_protein_kinase

  • P38 mitogen-activated protein kinases

    • Protein family

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    P38 mitogen-activated protein kinases

    P38_mitogen-activated_protein_kinases

  • MAP kinase kinase kinase kinase

    • Family of proteins

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MAP kinase kinase kinase kinase

    MAP_kinase_kinase_kinase_kinase

  • Polo-like kinase

    • Plk1 (Xenopus Plx1), Plk2/Snk (Xenopus Plx2), Plk3/Prk/FnK (Xenopus Plx3), Plk4/Sak and Plk5. Of the vertebrate Plk family members, the mammalian Plk1 has

    Polo-like kinase

    Polo-like_kinase

  • NLK

    • Mammalian protein found in Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    NLK

    NLK

    NLK

  • Protein kinase B

    • Set of three serine threonine-specific protein kinases

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Protein kinase B

    Protein kinase B

    Protein_kinase_B

  • MTORC1

    • Protein complex

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MTORC1

    MTORC1

    MTORC1

  • Mitogen-activated protein kinase

    • P38 mitogen-activated protein kinases

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Mitogen-activated protein kinase

    Mitogen-activated_protein_kinase

  • Titin

    • Largest known protein in human muscles

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Titin

    Titin

    Titin

  • Cyclin-dependent kinase

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Cyclin-dependent kinase

    Cyclin-dependent kinase

    Cyclin-dependent_kinase

  • Low-density-lipoprotein receptor kinase

    • Kinase enzyme involved in cholesterol homeostasis

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Low-density-lipoprotein receptor kinase

    Low-density-lipoprotein_receptor_kinase

  • C-Jun N-terminal kinases

    • Chemical compounds

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    C-Jun N-terminal kinases

    C-Jun N-terminal kinases

    C-Jun_N-terminal_kinases

  • Phosphorylase kinase

    • Enzyme involved in glycogenolysis

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Phosphorylase kinase

    Phosphorylase kinase

    Phosphorylase_kinase

  • IkappaB kinase

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    IkappaB kinase

    IkappaB_kinase

  • Protein kinase domain

    • Protein domain

    PIM3 ; PINK1 ; PKDCC ; PKMYT1 ; PKN1 ; PKN2 ; PKN3 ; PLK1 ; PLK2 ; PLK3 ; PLK4 ; PLK5 ; PNCK ; POMK ; PRKAA1 ; PRKAA2 ; PRKACA ; PRKACB ; PRKACG ; PRKCA ;

    Protein kinase domain

    Protein kinase domain

    Protein_kinase_domain

  • Extracellular signal-regulated kinases

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Extracellular signal-regulated kinases

    Extracellular_signal-regulated_kinases

  • VRK2

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    VRK2

    VRK2

    VRK2

  • GSK-3

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    GSK-3

    GSK-3

    GSK-3

  • Protein kinase A

    • Family of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Protein kinase A

    Protein kinase A

    Protein_kinase_A

  • MTORC2

    • Protein complex

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MTORC2

    MTORC2

  • RAF kinase

    • PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    RAF kinase

    RAF kinase

    RAF_kinase

  • Cell division cycle 7-related protein kinase

    • Protein found in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Cell division cycle 7-related protein kinase

    Cell division cycle 7-related protein kinase

    Cell_division_cycle_7-related_protein_kinase

  • Mitogen-activated protein kinase kinase

    • Kinase enzyme

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Mitogen-activated protein kinase kinase

    Mitogen-activated_protein_kinase_kinase

  • IDH3A

    • Protein-coding gene in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    IDH3A

    IDH3A

    IDH3A

  • Aurora inhibitor

    • Putative drug class for treating cancer

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Aurora inhibitor

    Aurora inhibitor

    Aurora_inhibitor

  • IRAK4

    • Protein-coding gene in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    IRAK4

    IRAK4

    IRAK4

  • RPS6KB2

    • Enzyme

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    RPS6KB2

    RPS6KB2

    RPS6KB2

  • Centrosome cycle

    • Centrioles are nine triplets microtubules

    (November 2015). "Asterless Reduction during Spermiogenesis Is Regulated by Plk4 and Is Essential for Zygote Development in Drosophila". Current Biology.

    Centrosome cycle

    Centrosome cycle

    Centrosome_cycle

  • Ca2+/calmodulin-dependent protein kinase II

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent protein kinase II

    Ca2+/calmodulin-dependent_protein_kinase_II

  • Protein kinase N1

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Protein kinase N1

    Protein kinase N1

    Protein_kinase_N1

  • CHUK

    • Protein-coding gene in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    CHUK

    CHUK

    CHUK

  • MAP2K3

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MAP2K3

    MAP2K3

    MAP2K3

  • Pyruvate dehydrogenase kinase

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Pyruvate dehydrogenase kinase

    Pyruvate dehydrogenase kinase

    Pyruvate_dehydrogenase_kinase

  • SIK1

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    SIK1

    SIK1

    SIK1

  • Tyrosine kinase

    • Enzyme

    MET; MLTK; MST1R; MUSK; NPR1; NTRK1; NTRK2; NTRK3; PDGFRA; PDGFRB; PKDCC; PLK4; PTK2; PTK2B; PTK6; PTK7; RET; ROR1; ROR2; ROS1; RYK; SRC; SRMS; STYK1; SYK;

    Tyrosine kinase

    Tyrosine kinase

    Tyrosine_kinase

  • MAP kinase kinase kinase

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MAP kinase kinase kinase

    MAP_kinase_kinase_kinase

  • Acetate kinase

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Acetate kinase

    Acetate kinase

    Acetate_kinase

  • P70-S6 Kinase 1

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    P70-S6 Kinase 1

    P70-S6 Kinase 1

    P70-S6_Kinase_1

  • Stratifin

    • Protein-coding gene in the species Homo sapiens

    in stratified epithelial cells. Stratifin has been shown to interact with PLK4, ERRFI1, MARK3, JUB and YWHAG. GRCh38: Ensembl release 89: ENSG00000175793

    Stratifin

    Stratifin

    Stratifin

  • Protein kinase C

    • Family of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Protein kinase C

    Protein_kinase_C

  • Anti-Müllerian hormone type-2 receptor

    • Protein receptor for anti-Müllerian hormone

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Anti-Müllerian hormone type-2 receptor

    Anti-Müllerian hormone type-2 receptor

    Anti-Müllerian_hormone_type-2_receptor

  • BMPR1B

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    BMPR1B

    BMPR1B

    BMPR1B

  • KSR1

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    KSR1

    KSR1

    KSR1

  • CAMK

    • Enzyme type

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    CAMK

    CAMK

  • Serine/threonine-specific protein kinase

    • Class of protein kinase enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Serine/threonine-specific protein kinase

    Serine/threonine-specific protein kinase

    Serine/threonine-specific_protein_kinase

  • AKT2

    • Protein found in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    AKT2

    AKT2

    AKT2

  • GRK4

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    GRK4

    GRK4

    GRK4

  • TTK (gene)

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    TTK (gene)

    TTK (gene)

    TTK_(gene)

  • Phototropin

    • Class of photoreceptor proteins in plants

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Phototropin

    Phototropin

  • Phosphatidylinositol 3-kinase-related kinase

    • Protein family

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Phosphatidylinositol 3-kinase-related kinase

    Phosphatidylinositol_3-kinase-related_kinase

  • Myosin light-chain kinase

    • Class of kinase enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Myosin light-chain kinase

    Myosin light-chain kinase

    Myosin_light-chain_kinase

  • Mónica Bettencourt-Dias

    • Portuguese biochemist and cellular biologist

    critical to metabolism and cell signalling. She discovered that the kinase PLK4 regulates the number of centrosomes an organism develops. Her simultaneous

    Mónica Bettencourt-Dias

    Mónica_Bettencourt-Dias

  • Ataxia telangiectasia and Rad3 related

    • Protein kinase that detects DNA damage and halts cell division

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Ataxia telangiectasia and Rad3 related

    Ataxia telangiectasia and Rad3 related

    Ataxia_telangiectasia_and_Rad3_related

  • MTOR

    • Mammalian protein found in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MTOR

    MTOR

    MTOR

  • MAP3K3

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MAP3K3

    MAP3K3

    MAP3K3

  • Aurora kinase A

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Aurora kinase A

    Aurora kinase A

    Aurora_kinase_A

  • Protein kinase R

    • Human protein and coding gene

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Protein kinase R

    Protein kinase R

    Protein_kinase_R

  • Rho-associated protein kinase

    • Protein family

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Rho-associated protein kinase

    Rho-associated protein kinase

    Rho-associated_protein_kinase

  • MAP3K13

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MAP3K13

    MAP3K13

    MAP3K13

  • SMG1

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    SMG1

    SMG1

    SMG1

  • PKMYT1

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    PKMYT1

    PKMYT1

    PKMYT1

  • BRAF (gene)

    • Protein-coding gene in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    BRAF (gene)

    BRAF (gene)

    BRAF_(gene)

  • Renata Basto

    • Researcher

    Simon, Anthony; Blanc, Damien; Racine, Victor; Kimata, Yuu (2019-07-01). "Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells"

    Renata Basto

    Renata_Basto

  • G protein-coupled receptor kinase

    • Family of protein kinases

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    G protein-coupled receptor kinase

    G protein-coupled receptor kinase

    G_protein-coupled_receptor_kinase

  • SGK

    • Protein family

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    SGK

    SGK

  • LRDD

    • Protein-coding gene in the species Homo sapiens

    of cytokinesis failure. In contrast, overexpressing polo-like kinase 4 (PLK4), which promotes the formation of additional centrosomes, is sufficient to

    LRDD

    LRDD

    LRDD

  • Wee1

    • Nuclear protein

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Wee1

    Wee1

    Wee1

  • GRK5

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    GRK5

    GRK5

    GRK5

  • CGMP-dependent protein kinase

    • Protein kinase

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    CGMP-dependent protein kinase

    CGMP-dependent protein kinase

    CGMP-dependent_protein_kinase

  • KIAA0753

    • identified that centrosome duplication is regulated by the following proteins: PLK4, CEP192, CEP152, CEP63, and CPAP. Among these, they found that CEP63 interacts

    KIAA0753

    KIAA0753

  • C5orf34

    • Protein-coding gene in the species Homo sapiens

    is also predicted to have a polo-box domain (PBD) of polo-like kinase 4 (plk4), which has predicted conservation in distant orthologs from the clade Aves

    C5orf34

    C5orf34

  • Ribosomal s6 kinase

    • Family of protein kinases

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Ribosomal s6 kinase

    Ribosomal s6 kinase

    Ribosomal_s6_kinase

  • PLK1

    • Mammalian protein found in Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    PLK1

    PLK1

    PLK1

  • Myotonin-protein kinase

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Myotonin-protein kinase

    Myotonin-protein kinase

    Myotonin-protein_kinase

  • VRK1

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    VRK1

    VRK1

    VRK1

  • Cyclin-dependent kinase 8

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Cyclin-dependent kinase 8

    Cyclin-dependent kinase 8

    Cyclin-dependent_kinase_8

  • GAK (protein)

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    GAK (protein)

    GAK (protein)

    GAK_(protein)

  • Casein kinase 1

    • Family of protein kinases

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Casein kinase 1

    Casein_kinase_1

  • STK11

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    STK11

    STK11

    STK11

  • CHEK1

    • Protein-coding gene in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    CHEK1

    CHEK1

    CHEK1

  • NUAK1

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    NUAK1

    NUAK1

    NUAK1

  • MTOR inhibitors

    • Class of pharmaceutical drugs

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MTOR inhibitors

    MTOR inhibitors

    MTOR_inhibitors

  • SASS6

    • Protein-coding gene in the species Homo sapiens

    PMID 15572125. Kleylein-Sohn J, Westendorf J, Le Clech M, et al. (2007). "Plk4-induced centriole biogenesis in human cells". Dev. Cell. 13 (2): 190–202

    SASS6

    SASS6

    SASS6

  • DNA-PKcs

    • Protein found in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    DNA-PKcs

    DNA-PKcs

    DNA-PKcs

  • 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase

    3-methyl-2-oxobutanoate_dehydrogenase_(acetyl-transferring)_kinase

  • MAP3K14

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MAP3K14

    MAP3K14

    MAP3K14

  • BCKDK

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    BCKDK

    BCKDK

    BCKDK

  • MASTL

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MASTL

    MASTL

    MASTL

  • MAPKAPK2

    • Protein-coding gene in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MAPKAPK2

    MAPKAPK2

    MAPKAPK2

  • MAP2K4

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    MAP2K4

    MAP2K4

    MAP2K4

  • G protein-coupled receptor kinase 3

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    G protein-coupled receptor kinase 3

    G protein-coupled receptor kinase 3

    G_protein-coupled_receptor_kinase_3

  • Receptor protein serine/threonine kinase

    • Class of enzymes

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Receptor protein serine/threonine kinase

    Receptor_protein_serine/threonine_kinase

  • RPS6KC1

    • Enzyme found in humans

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    RPS6KC1

    RPS6KC1

    RPS6KC1

  • Cyclin-dependent kinase 4

    • Human protein

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    Cyclin-dependent kinase 4

    Cyclin-dependent kinase 4

    Cyclin-dependent_kinase_4

  • ACVR1

    • Protein-coding gene

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    ACVR1

    ACVR1

    ACVR1

  • PRKAG2

    • Protein-coding gene in the species Homo sapiens

    PLK1 PLK2 PLK3 PLK4 Serine/threonine-specific protein kinases (EC 2.7.11.21-EC 2.7.11.30) Polo kinase (EC 2.7.11.21) PLK1 PLK2 PLK3 PLK4 Cyclin-dependent

    PRKAG2

    PRKAG2

    PRKAG2

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Online names & meanings

  • Anisa | انیسا

    • Girl/Female

    Muslim

    Anisa | انیسا

    Friendly, Of good company

  • Noorie

    • Girl/Female

    Indian

    Noorie

    Light

  • Haridas | ஹரிதாஸ 

    • Boy/Male

    Tamil

    Haridas | ஹரிதாஸ 

    Servant of Krishna

  • Paranjay | பராந்ஜய

    • Boy/Male

    Tamil

    Paranjay | பராந்ஜய

    Varun, Lord of the sea

  • Naum

    • Boy/Male

    Australian, Biblical, German, Hebrew

    Naum

    Comforter; Penitent

  • BRÍDIN

    • Female

    Irish

    BRÍDIN

    Diminutive form of Irish Gaelic Bríd, BRÍDIN means "little exalted one."

  • Shafa

    • Girl/Female

    Arabic

    Shafa

    Cure

  • Hemantika

    • Girl/Female

    Indian

    Hemantika

    Princess; Patience; Doll

  • Gaynor

    • Girl/Female

    Arthurian Legend

    Gaynor

    Fair one. Guinevere was King Arthur's mythological queen.

  • Adrianna

    • Girl/Female

    French American

    Adrianna

    From Adria, the Adriatic sea region. Also means dark.

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