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Genetically modified mouse used in gene research
A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing
Knockout_mouse
Small long-tailed rodent
A knockout mouse is a genetically modified mouse that has had one or more of its genes made inoperable through a gene knockout. Experimental mouse model
Mouse
Genetic technique
create knockout mice. With the aid of gene targeting, numerous mouse genes have been shut down, leading to the creation of hundreds of distinct mouse models
Gene_knockout
William; Rosen, Barry; et al. (2011). "A conditional knockout resource for the genome-wide study of mouse gene function". Nature. 474 (7351): 337–342. doi:10
Conditional_gene_knockout
American pharmaceutical company
Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000
Lexicon_Pharmaceuticals
Variety of genetically modified laboratory mice
they will not sell the woolly mouse, and that they will remain private for further de-extinction research. Knockout mouse Oncomouse Davis, Nicola (March
Woolly_mouse
Species of mammal
a model organism, a great deal is known about mouse genetics, with a major tool being the knockout mouse technique. House mice usually live less than one
House_mouse
International Mouse Phenotyping Consortium (IMPC) is an international scientific endeavour to create and characterize the phenotype of 20,000 knockout mouse strains
International Mouse Phenotyping Consortium
International_Mouse_Phenotyping_Consortium
Type of genetically engineered rat
that are unavailable in the mouse. Knockout rat models can also complement existing transgenic mouse models. Comparing mouse and rat mutants can facilitate
Knockout_rat
Genetically engineered variety of rose
Eucalyptus Mustard Animals Mammals Mouse Knockout mouse Oncomouse Woolly mouse Gene-edited human Enviropig Herman the Bull Knockout rat Rabbit Ruppy Wolves Other
Blue_rose
Acquired allergy resulting from tick bites
in the context of tick bites has been confirmed using an alpha-gal knockout mouse model. Tick larvae, nymphs, and adults can cause AGS. Tick larvae are
Alpha-gal_syndrome
Mouse with altered genomes
A genetically modified mouse, genetically engineered mouse model (GEMM) or transgenic mouse is a mouse (Mus musculus) that has had its genome altered
Genetically_modified_mouse
Congenital extreme form of developmental delay and neoteny
disorder. A mutation in one gene (TMEM63B) was identified in a large knockout mouse study as likely to result in disease in humans. In two patients, a small
Neotenic_complex_syndrome
Ramberg Capecchi (born 1937), and Oliver Smithies (1925–2017), U.S. – Knockout mouse, Gene targeting Ole Evinrude (1877–1934), Norway – outboard motor Charles
List_of_inventors
British biologist
Capecchi and Oliver Smithies, for his work in the development of the knockout mouse and the related technology of gene targeting, a method of using embryonic
Martin_Evans
Mouse carrying functioning human genes, cells, etc.
Nude mouse SCID mouse NOG mouse NSG mouse Mouse model of colorectal and intestinal cancer Mouse models of breast cancer metastasis Knockout mouse Chuprin
Humanized_mouse
Chemical compound
hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse". American Journal of Physiology. Endocrinology and Metabolism. 291
CJC-1295
American biotechnology company
Eucalyptus Mustard Animals Mammals Mouse Knockout mouse Oncomouse Woolly mouse Gene-edited human Enviropig Herman the Bull Knockout rat Rabbit Ruppy Wolves Other
AquaBounty_Technologies
Biomedical research institution
modeling. The National Institutes of Health (NIH) funds phase 2 of the Knockout Mouse Production and Phenotyping Project (KOMP2). Researchers link mutations
Jackson_Laboratory
Lipid-containing residue associated with aging
this holds in vivo over longer time periods is not clear. The ABCR -/- knockout mouse has delayed dark adaptation but normal final rod threshold relative
Lipofuscin
Topics referred to by the same term
KOMP 104.9 Radio Compa, an album by Akwid Knockout Mouse Program (KOMP), part of the International Knockout Mouse Consortium Comp (disambiguation) This disambiguation
Komp
Scientific project organization
The International Knockout Mouse Consortium (IKMC) is a scientific endeavour to produce a collection of mouse embryonic stem cell lines that together
International Knockout Mouse Consortium
International_Knockout_Mouse_Consortium
Class of chemical compounds
HG; Gonzalez, FJ; Nebert, DW (2006). "Oral Benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required
Benzopyrene
Sequence of DNA that determines traits in an organism
Bradley A, Bucan M, Capecchi M, Collins FS, et al. (September 2004). "The knockout mouse project". Nature Genetics. 36 (9): 921–4. Bibcode:2004NaGen..36..921
Gene
Protein-coding gene in humans
ultimately lead to cancer due to the loss of function as a sensor. Runx3 null mouse gastric mucosa exhibits hyperplasia due to stimulated proliferation and
RUNX3
Exocrine gland in humans and other mammals
Broadus, A. E. (1998). "Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for
Mammary_gland
Medication
a major role in social reward in animals and the μ-opioid receptor knockout mouse is an animal model of autism. Studies on whether naltrexone can decrease
Naltrexone
One of five Nobel Prizes established in 1895 by Alfred Nobel
mice, employing embryonic stem cells through the development of the knockout mouse. In 2009, the Nobel Prize was awarded to Elizabeth Blackburn, Carol
Nobel Prize in Physiology or Medicine
Nobel_Prize_in_Physiology_or_Medicine
Uncontrolled gene flow into wild populations
Eucalyptus Mustard Animals Mammals Mouse Knockout mouse Oncomouse Woolly mouse Gene-edited human Enviropig Herman the Bull Knockout rat Rabbit Ruppy Wolves Other
Genetic_pollution
Iron and oxygen-binding protein
Laussmann T, Flögel U, et al. (Apr 2004). "Adaptation of the myoglobin knockout mouse to hypoxic stress". American Journal of Physiology. Regulatory, Integrative
Myoglobin
Class of animals with milk-producing glands
mice and rats, are used in experiments each year. A knockout mouse is a genetically modified mouse with an inactivated gene, replaced or disrupted with
Mammal
X-linked dominant genetic disorder
(2002). "Behavioral and neuroanatomical characterization of the Fmr1 knockout mouse". Hippocampus. 12 (1): 39–46. doi:10.1002/hipo.10005. ISSN 1050-9631
Fragile_X_syndrome
Fatty substance insulating nerve cell axons
K, Surendran S, Tyring SK (2006). "Canavan disease: studies on the knockout mouse". N-Acetylaspartate. Advances in Experimental Medicine and Biology.
Myelin
Critical protein in embryonic development
Additionally, a double (SHH-/- ) knockout mouse model exhibited poor lung development. The lungs of the SHH double knockout failed to undergo lobation and
Sonic_hedgehog_protein
Common strain of laboratory mouse
therefore it is used even more. In 1993 the first C57BL/6 gene targeted knockout mouse was published by a group at Hoffmann-La Roche in Switzerland. In 2013
C57BL/6
Popular model for studying Duchenne muscular dystrophy
the mouse model and human disease. To overcome these limitations, researchers have developed improved models such as the mdx/utrophin double knockout mouse
Mdx_mouse
Long projection on a neuron that conducts signals to other neurons
K, Surendran S, Tyring SK (2006). "Canavan Disease: Studies on the Knockout Mouse". N-Acetylaspartate. Advances in Experimental Medicine and Biology.
Axon
Biological process in primates
with a high GH secretion. An animal model of Laron syndrome, the GHR knockout mouse, shows severely impaired ductal outgrowth at 11 weeks of age. However
Breast_development
Human protein
phenotype. Foxp3 expression is not affected by loss of CD83 in a CD83 knockout mouse. In contrast, CD83 seems important for peripheral Treg cell induction
CD83
mutant genes. The EUCOMM consortium is a member of the International Knockout Mouse Consortium, (an organisation including the EUCOMM, KOMP, NorCOMM and
EUCOMM
Blood proteins made in the liver and secreted into the bloodstream
drastically exacerbated when the fetuin-A knockout was combined with the genetic background DBA/2. The mouse strain DBA/2 is known for its proneness to
Fetuin
Genome engineering tools
enable complete functional annotation of the mouse genome (coordinated by the International Knockout-Mouse Consortium, IKMC) with the ultimate goal to
Site-specific recombinase technology
Site-specific_recombinase_technology
Genetic technique that uses homologous recombination to change an endogenous gene
mice, the DNA is inserted into mouse embryonic stem cells in culture. Cells with the insertion can contribute to a mouse's tissue via embryo injection.
Gene_targeting
Rare metabolic disorder
and cerebellar fatty acid profiles in a Purkinje cell-specific Mecr knockout mouse model, but did not prevent Purkinje cell loss or neurodegeneration.
MEPAN_syndrome
Protein-coding gene in the species Homo sapiens
jellyfish, anemones) with a conserved protein domain composition. Using knockout mouse models of TNFAIP3 and its transcriptional repressor (i.e. KCHIP3), TNFAIP3
TNFAIP3
Species of virus
Fever (CCHF) infections in suckling mice and in the interferon receptor knockout mouse model This indicates that Hazara orthonairovirus could represent a valid
Hazara_virus
(born 1937), Italian-born US molecular geneticist, co-invented the knockout mouse, Nobel Prize in Medicine, 2007 Elof Axel Carlson (born 1931), US geneticist
List_of_geneticists
Glycoprotein found in humans
lacritin promotes tearing in rabbit preclinical studies. In the Aire knockout mouse model of dry eye (considered similar to human Sjogren's syndrome), topical
Lacritin
Central nervous system stimulant
alertness. Caffeine is an antagonist of adenosine A2A receptors, and knockout mouse studies have specifically implicated antagonism of the A2A receptor
Caffeine
Opioid used to treat pain and opioid use disorder
activation by beta-endorphin in pons/medulla of the mu-opioid receptor knockout mouse". Neuroscience. 115 (3): 715–721. doi:10.1016/s0306-4522(02)00486-4
Buprenorphine
American immunologist
biological, biochemical, and in vivo analyses using transgenic and knockout mouse models, and models of human inflammatory diseases including arthritis
Kodi_Ravichandran
Medical condition
G.; Carlson, M.; Lockridge, O. (2007). "The Butyrylcholinesterase Knockout Mouse as a Model for Human Butyrylcholinesterase Deficiency". Journal of Pharmacology
Butyrylcholinesterase deficiency
Butyrylcholinesterase_deficiency
Lab mouse strain lacking immunity and fur
A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune
Nude_mouse
Class of immune system proteins
fever in humans. TLR11 deficient knockout mice, on the other hand, are efficiently infected. As a result, this knockout mouse can act as a disease model of
Toll-like_receptor
Group of enzymes
through which environmental toxicants contribute to PD pathogenesis." Knockout mouse models further confirm the involvement of ALDH family in neurodegeneration
Aldehyde_dehydrogenase
Organic compound, a stimulant in humans
Borowsky B, Seeman P, et al. (October 2007). "The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia". Genes Brain Behav
Phenethylamine
Protein that initiates male sex determination in therian mammals
Yamashita S, Tamano M, Miura K, et al. (November 2013). "Production of Sry knockout mouse using TALEN via oocyte injection". Scientific Reports. 3 (1) 3136. Bibcode:2013NatSR
Sex-determining region Y protein
Sex-determining_region_Y_protein
Free-radical aging theory
(2009). "The mitochondrial theory of aging: Insight from transgenic and knockout mouse models". Experimental Gerontology. 44 (4): 256–60. doi:10.1016/j.exger
Free-radical_theory_of_aging
Class of compounds
(in TAAR1-DAT cells or wild-type mouse striatal synaptosomes) than in its absence (in DAT cells or TAAR1 knockout mouse striatal synaptosomes), and it was
Monoamine_releasing_agent
Free radical toxicity
"Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency".
Oxidative_stress
Chemical compound
tested and found to be non-carcinogenic when using the established p53 knockout mouse model. The technology is currently in routine use in certain European
Psoralen
Scientific endeavours to determine the complete genome sequence of an organism
Project 100K Pathogen Genome Project International Mouse Phenotyping Consortium IMPC Knockout Mouse Phenotyping Project KOMP2 Giant Sequoia, Sequoiadendron
Genome_project
Small-molecule oxytocin receptor agonist
LIT-001 reduces social deficits in a mouse model of autism, specifically the μ-opioid receptor knockout mouse model. It was the first small-molecule
LIT-001
Italian-American molecular geneticist (born 1937)
sister. Capecchi was awarded the Nobel prize for creating a knockout mouse. This is a mouse, created by genetic engineering and in vitro fertilization
Mario_Capecchi
American biologist
characterization of the world's longest lived laboratory mouse, the growth hormone receptor knockout mouse. Dr. Kopchick has an h-index of 80, has advised more
John_Kopchick
Sanger Institute, the project uses knockout mice most of which were generated by the International Knockout Mouse Consortium. For each mutant line, groups
Mouse_Genetics_Project
Genetically modified mouse for cancer research
of Virginia. Animal testing Biobreeding rat Biological patent Knockout mouse Woolly mouse European Patent Register entry for European patent no. 0169672
Oncomouse
Capecchi (born 1937) Italy United States "for the development of the knockout mouse and the related technology of gene targeting, a method of using embryonic
List of Clarivate Citation laureates in Physiology or Medicine
List_of_Clarivate_Citation_laureates_in_Physiology_or_Medicine
Oil spill involving two Russian oil tankers
HG; Gonzalez, FJ; Nebert, DW (2006). "Oral Benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required
2024_Black_Sea_oil_spill
American biochemist and academic
J. A., Lust, R. M., & Clemens, S. (2013). The dopamine D3 receptor knockout mouse mimics aging-related changes in autonomic function and cardiac fibrosis
Tracy_L._Johnson
Protein found in humans
adrenocortical carcinoma patients. Mouse models where the Jag1 gene is turned off in certain tissues (conditional knockout mouse models) have been used to study
JAG1
Protein-coding gene in the species Homo sapiens
is largely unknown due to unidentified direct binding partners. Many knockout mouse models with tendon phenotypes have helped in understanding which upstream
Tenomodulin
Medical condition
citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent's disease". Kidney Int. 68 (2): 642–52. doi:10.1111/j
Dent's_disease
Protein-coding gene in the species Homo sapiens
been investigated using Eid1-knockout mouse models. In one transcriptomic study, RNA sequencing of the Eid1-knockout mouse brain identified 2,531 genes
EID1
Protein-coding gene in humans
lungs, and central nervous system. In a study by Naiche et al., a knockout mouse lacking Tbx4 expression failed to develop limbs, demonstrating the gene’s
TBX4
Medical condition
"Schneckenbecken dysplasia". In 2007, Hiraoka et al. created an SLC35D1-knockout mouse model, said experiment revealed that while mice heterozygous for the
Schneckenbecken_dysplasia
Protein found in humans
Stargardt's disease and macular degeneration. An animal study using ABCA4 knockout mouse proved that reduction in serum RBP4 level could inhibit lipofuscin without
Retinol_binding_protein_4
Behavioral measure in animals
Branchek T, Gerald CP (October 2007). "The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia". Genes Brain Behav
Locomotor_activity
Rare autosomal dominant cancer syndrome
removed without taking the whole kidney, in a partial nephrectomy. Knockout mouse studies have shown that administration of rapamycin may mitigate the
Birt–Hogg–Dubé_syndrome
Glycomics research initiative
conditional knockout mouse lines deficient in glycan-binding proteins or glycosyltransferases. All Core F strains are now archived at the Mutant Mouse Regional
Consortium for Functional Glycomics
Consortium_for_Functional_Glycomics
Medical condition
Hill RA, Boon WC (2009). "Estrogens, brain, and behavior: lessons from knockout mouse models" (PDF). Semin. Reprod. Med. 27 (3): 218–28. doi:10.1055/s-0029-1216275
Estrogen insensitivity syndrome
Estrogen_insensitivity_syndrome
American scientist
"Antipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model". Molecular Autism. 6 (1): 1. doi:10.1186/2040-2392-6-1. ISSN 2040-2392
Robert_K._Naviaux
Class of proteins
heterodimers are critical for platelet production. Knockout mouse studies have shown that MafG knockout mice show mild thrombocytopenia, whereas MafG and
Small_Maf
American molecular biologist and Nobel laureate
collaboration with Ronald A. DePinho, produced the first telomerase knockout mouse, showing that although telomerase is dispensable for life, increasingly
Carol_W._Greider
Protein found in humans
involved in cell adhesion, its biological function is not known. A knockout mouse line that lacks mesothelin reproduces and develops normally. Mesothelin
Mesothelin
Organism altered by genetic engineering
predisposing them to developing cancer. Mice with genes removed (termed a knockout mouse) were created in 1989. The first transgenic livestock were produced
Genetically_modified_organism
Protein-coding gene in the species Homo sapiens
developing mouse embryo, CYP26B1 is expressed in the distal tip of the forming limb bud with an abundance in the apical ectodermal ridge. In a knockout mouse model
CYP26B1
Mouse used for scientific research
The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory
Laboratory_mouse
Egyptian-American medical researcher
and to use molecular imaging for drug screening. His group created a knockout mouse of death receptor 5 (DR5) that shows reduced apoptosis in vivo after
Wafik_El-Deiry
Mammalian protein found in Homo sapiens
stability of sperm chromatin, yet both knockout mouse models (for mGPX4 and nGPX4) were fully viable. Surprisingly, knockout of GPX4 heterozygously in mice (GPX4+/−)
Glutathione_peroxidase_4
Medication used for alcohol intoxication
occur in 59-80% of individuals with FXS. In a FXS animal model (Fmr1 knockout mouse model), metadoxine treatment improved behavioral impairments of learning
Metadoxine
presentation and enlarge the pool of cTEC unique peptide ligands. Ctsl knockout mouse revealed severe reduction in frequency and repertoire of CD4 T cells
Cortical thymic epithelial cells
Cortical_thymic_epithelial_cells
the production of a knockout mouse. This is accomplished through the administration of one or more transgenes into a fertilized mouse oocyte’s pronucleus
Genetic_ablation
Italian neuroscientist
Lawrence Wrabetz, Feltri pioneered the use of transgenic and conditional knockout mouse models to study inherited demyelinating neuropathies, including Charcot–Marie–Tooth
M._Laura_Feltri
Test to measure pain
Wilson, Sonya G.; Mogil, Jeffrey S. (2001). "Measuring pain in the (knockout) mouse: Big challenges in a small mammal". Behavioural Brain Research. 125
Nociception_assay
Animal gene
delays DNA repair in multiple cell lines. Mouse embryo fibroblasts (MEFs) derived from a Cux1-/- knockout mouse exhibit increased genomic instability23
CUX1
Life science research institute in Hyderabad, India
people among Indians Developed the first genetically engineered, gene knockout mouse in India Demonstrated the first artificial insemination in spotted deer
Centre for Cellular and Molecular Biology
Centre_for_Cellular_and_Molecular_Biology
been used to generate mice with genes knocked out. The first recorded knockout mouse was created by Mario R. Capecchi, Martin Evans and Oliver Smithies in
History of genetic engineering
History_of_genetic_engineering
used to study cellular and tissue-specific responses to disease (cf knockout mouse). This is possible since mice can be created with the same mutations
Genetically_modified_mammal
Protein-coding gene in the species Homo sapiens
(May 2011). "Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse". The Journal of Cell Biology. 193 (5): 935–51. doi:10.1083/jcb.201007162
TANGO1/MIA3
KNOCKOUT MOUSE
KNOCKOUT MOUSE
Boy/Male
Hindu, Indian
Mouse
Surname or Lastname
English
English : habitational name from Muscott, a minor place in Northamptonshire, or Muscoates in North Yorkshire, both named from Old English mūs ‘mouse’ + cot ‘hut’, ‘small dwelling’, ‘shelter’.
Male
Native American
Native American Algonquin name ABUKCHEECH means "mouse."
Boy/Male
Hindu
One who has mouse as charioteer
Boy/Male
Tamil
One who has mouse as his charioteer
Male
Greek
Variant spelling of Greek Moyses, MOUSES means "drawn out." In the bible, this is the name of the leader who brought the Israelites out of bondage and led them to the promised land.Â
Boy/Male
Australian, British, English
Of Cornish Hen Mouse and Luster; Moon
Boy/Male
Native American
Mouse.
Male
Welsh
Welsh form of Hebrew Moshe and Greek Mouses, MOESEN means "drawn out."
Girl/Female
Biblical
A house for a mouse.
Male
English
Anglicized form of Hebrew Moshe and Greek Mouses, MOSES means "drawn out." In the bible, this is the name of the leader who brought the Israelites out of bondage and led them to the promised land.Â
Male
Italian
Italian form of Hebrew Moshe (Greek Mouses), MOSÈ means "drawn out."
Boy/Male
Tamil
Musikvahana | à®®à¯à®¸à¯€à®•à¯à®µà®¾à®¹à®¾à®¨à®¾Â
One who has mouse as charioteer
Musikvahana | à®®à¯à®¸à¯€à®•à¯à®µà®¾à®¹à®¾à®¨à®¾Â
Surname or Lastname
English
English : nickname from Middle English mūs ‘mouse’ + ēage ‘eye’.Possibly an altered spelling of French Musset (see Mussett 1).
Surname or Lastname
English (Cumbria)
English (Cumbria) : habitational name from either of two villages in Cumbria, named in Old English with mÅ«s ‘mouse’ (perhaps a byname) + grÄf ‘grove’ (see Grove 1). The Norman surname de Mucegros, established in Herefordshire and elsewhere in the 12th and 13th centuries, is unrelated and has died out.
Surname or Lastname
English
English : habitational name from either of the places in Leicestershire and North Yorkshire so named, from Old English mūs ‘mouse’ + tūn ‘enclosure’, ‘settlement’. The Yorkshire Muston may alternatively have been called ‘Músi’s farmstead’, from an Old Scandinavian personal name + tūn.
Surname or Lastname
English (chiefly southern Yorkshire and Lancashire)
English (chiefly southern Yorkshire and Lancashire) : habitational name from any of several places called Mos(e)ley in central, western, and northwestern England. The obvious derivation is from Old English mos ‘peat bog’ + lēah ‘woodland clearing’, but the one in southern Birmingham (Museleie in Domesday Book) had as its first element Old English mūs ‘mouse’, while one in Staffordshire (Molesleie in Domesday Book) had the genitive case of the Old English byname Moll.
Surname or Lastname
English (Hertfordshire)
English (Hertfordshire) : nickname from titmose ‘tit(mouse)’, applied to someone thought to resemble the bird.
Girl/Female
Egyptian Latin Russian
Mouse.
Boy/Male
Hindu, Indian, Kannada, Telugu
One who has Mouse as his Charioteer
KNOCKOUT MOUSE
KNOCKOUT MOUSE
Boy/Male
Tamil
Sober
Boy/Male
Hindu, Indian, Kannada, Sindhi, Telugu
One who has Two Mothers
Girl/Female
Muslim
Candle. Wax.
Girl/Female
Tamil
Humsiha | ஹà¯à®®à®¸à¯€à®¹à®¾Â
Saraswati, Luckiest girl
Girl/Female
Tamil
Mithusha | மீதà¯à®·à®¾Â
Brilliant girl
Girl/Female
Italian American
God is gracious.
Male
English
 English form of German Walther, WALTER means "ruler of the army."
Boy/Male
Tamil
It is a vedic meter
Girl/Female
Afghan, Arabic
Pure; Clean; Chaste
Girl/Female
Tamil
Padmakali | பதà¯à®®à®¾à®•à®²à¯€
Lotus bud
KNOCKOUT MOUSE
KNOCKOUT MOUSE
KNOCKOUT MOUSE
KNOCKOUT MOUSE
KNOCKOUT MOUSE
v. t.
To furnish with a mouse; to secure by means of a mousing. See Mouse, n., 2.
n.
A little mouse.
v. t.
To tear, as a cat devours a mouse.
n.
A genus of plants. See Mouse-ear.
n.
Any flying marsupial of the genera Petaurus, Phalangista, Acrobata, and allied genera. See Flying mouse, under Flying, and Phalangister.
n.
Any one of numerous species of small rodents belonging to the genus Mus and various related genera of the family Muridae. The common house mouse (Mus musculus) is found in nearly all countries. The American white-footed, or deer, mouse (Hesperomys leucopus) sometimes lives in houses. See Dormouse, Meadow mouse, under Meadow, and Harvest mouse, under Harvest.
n.
A genus of small rodents, including the common mouse and rat.
n.
The act of coming forth; a leaving of houses, shops, etc.; esp., a quitting of employment for the purpose of forcing increase of wages; a strike; -- opposed to lockout.
n.
A small nocturnal and arboreal Australian marsupial (Tarsipes rostratus) about the size of a mouse. It has a long muzzle, a long tongue, and very few teeth, and feeds upon honey and insects. Called also noolbenger.
a.
Pertaining to a family of rodents (Muridae), of which the mouse is the type.
n.
One who pries about on the lookout for something.
n.
Diminutive for Mouse.
n.
The closing of a factory or workshop by an employer, usually in order to bring the workmen to satisfactory terms by a suspension of wages.
n.
One of a tribe of rodents, of which the mouse is the type.
n.
A genus of ranunculaceous plants (Myosurus), in which the prolonged receptacle is covered with imbricating achenes, and so resembles the tail of a mouse.
n.
A hole made by a mouse, for passage or abode, as in a wall; hence, a very small hole like that gnawed by a mouse.
imp. & p. p.
of Mouse