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See searches and references containing GALECTIN 8!GALECTIN 8
Protein family binding to β-galactoside sugars
peptide domain. Tandem galectins include galectin-4, -6, -8, -9 and -12. The final galectin is galectin-3 which is the only galectin found in the chimera
Galectin
Protein found in humans
Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene. This gene encodes a member of the galectin family. Galectins
Galectin-8
Process of cells digesting parts of themselves
involved in response to lysosomal damage, often directed by galectins such as galectin-3 and galectin-8. Repair of damaged DNA involves the recruitment of enzymes
Autophagy
Mammalian protein found in humans
At the heart of GALTOR is galectin-8, a member of β-galactoside binding superfamily of cytosolic lectins termed galectins, which recognizes lysosomal
MTOR
Protein-coding gene in the species Homo sapiens
Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9
Galectin-9
(January 2012). "Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion". Nature. 482 (7385): 414–8. Bibcode:2012Natur
Felix_Armin_Randow
Protein complex
lumen. Under homeostatic conditions, Galectin-8 associates with active mTOR. Following membrane damage, galectin-8 switches from mTOR to complexes containing
MTORC1
Protein-coding gene in the species Homo sapiens
Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have
Galectin-3
Prevalent tubulovesicular membranes
subunits and causes a bending of the membrane. Proteins like galectin-3, galectin 8, and GSL-dependent cellular endocytosis of CD166 are all known to
Clathrin-independent endocytosis
Clathrin-independent_endocytosis
Mammalian protein found in Homo sapiens
Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". J
Integrin_alpha_4
Mammalian protein found in Homo sapiens
Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (July 2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". J
Integrin_alpha_3
Mammalian protein found in Homo sapiens
Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (Jul 2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". Journal
Integrin_beta_1
Protein-coding gene in the species Homo sapiens
Placental protein 13 (PP13, also known as galectin-13) is a protein that in humans is encoded by the LGALS13 gene. It is composed of two identical subunits
LGALS13
Protein-coding gene in humans
Galectin-10 is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional
CLC_(gene)
Precursor cells of neurons and glia during embryonic development
oligodendrocytes or neuronal cells that secreted neuroprotective factors. Galectin-1 is expressed in adult NSCs and has been shown to have a physiological
Neural_stem_cell
Protein-coding gene in the species Homo sapiens
Galectin-2 is a protein that in humans is encoded by the LGALS2 gene. The protein encoded by this gene is a soluble beta-galactoside binding lectin. The
Galectin-2
American business people
spa, and gift shops. Richard Uihlein is the chairman of the board for Galectin Therapeutics, a publicly traded biotech company focusing on treatments
Richard_and_Elizabeth_Uihlein
Chemical compound
Selvigaltin (GB1211) is the first small-molecule, orally delivered galectin-3 inhibitor to be discovered. It is developed by Galecto Biotech, which is
Selvigaltin
Suborder of fishes
confirmed to be within the venom are cystatins, peroxiredoxin and galectin. Galectin induces cell death in its victims and cystatins inhibit defense enzymes
Stingray
American geneticist
damage: GALTOR (galectin-8–mTOR) links endomembrane damage to autophagy, galectin-3 recruits ESCRTs for lysosome repair, and galectin-9 activates AMPK
Vojo_Deretic
American neurosurgeon and government official (born 1951)
July 1, 2013. In 2021, Carson joined Galectin Therapeutics to assist with development of the company's galectin-3 inhibitor, belapectin, as a treatment
Ben_Carson
Argentine biochemist
how such tumors can be regressed. He also looked at the properties of galectins, and how they show potential for disease. Rabinovich was born in Córdoba
Gabriel_A._Rabinovich
Protein-coding gene in the species Homo sapiens
Galectin-related protein, also known as HSPC159, is a human gene. GRCh38: Ensembl release 89: ENSG00000119862 – Ensembl, May 2017 GRCm38: Ensembl release
HSPC159
Russian scientist (born 1946)
Atlanta, GA. The company was renamed as Galectin Therapeutics in May 2011. The company was renamed as Galectin Therapeutics in May 2011. He then became
Anatole_Klyosov
Protein-coding gene in the species Homo sapiens
glycan-binding sites is recognizes by carbohydrate domain of another ligands galectin-9 (Gal-9). The mucin domain is variable in a member of the TIM family,
HAVCR2
Protein-coding gene in the species Homo sapiens
Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating
Galectin-4
Andrea; Carpi, Federico; Mechanick, Jeffrey I.; Bartolazzi, Armando (2010). "Galectin-3 detection on large-needle aspiration biopsy improves preoperative selection
List_of_statistical_tests
Antibody isotype
IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44". Immunity. 49 (4): 709–724.e8. doi:10.1016/j.immuni.2018.08
Immunoglobulin_D
Human chromosome
thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit HSPC159: Galectin-related protein ID2-AS1: encoding protein Id2 antisense rna 1 (head to
Chromosome_2
Cytokine protein
been shown to interact with interleukin-6 receptor, glycoprotein 130, and Galectin-3. There is considerable functional overlap and interaction between Substance
Interleukin_6
Type of endocrine gland cancer
approach involves the use of immunotherapy, such as oncolytic viruses. Galectin-specific mechanisms of the tumor microenvironment are under study. Because
Pancreatic_cancer
Group of immune cells in the bone marrow
evidence for inhibiting Galectin-3 as a therapeutic target to reduce MDSCs. In a Phase 1b clinical trial of GR-MD-02 developed by Galectin Therapeutics, investigators
Myeloid-derived suppressor cell
Myeloid-derived_suppressor_cell
Species of virus
PMC 5457962. PMID 27578435. BCoV S1-NTD does not recognize galactose as galectins do. Instead, it recognizes 5-N-acetyl-9-O-acetylneuraminic acid (Neu5
Human_coronavirus_OC43
Stinging cell used by cnidarians
composed of polymerized NOWA (Nematocyst Outer Wall Antigen) proteins. Nemato Galectin, minicollagen Ncol-15 and chondroitin are novel proteins used to build
Cnidocyte
Defense mechanism of tumors against immunity
proteins that can deliver death signals in leukocytes (Fas ligand and galectin-1). The formation of a leukocyte infiltrate at places of inflammation is
Endothelial_cell_anergy
Class of peptides that have antimicrobial activity
Al-Dhabi NA, Arockiaraj J (June 2017). "Bactericidal activity of fish galectin 4 derived membrane-binding peptide tagged with oligotryptophan". Developmental
Antimicrobial_peptides
Class of enzymes
MH, Kimura T, et al. (October 2016). "TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis"
AMP-activated_protein_kinase
Type of breast cancer lacking certain gene expressions
"Binding of galectin-1 to integrin β1 potentiates drug resistance by promoting survivin expression in breast cancer cells". Oncotarget. 8 (22): 35804–35823
Triple-negative_breast_cancer
Protein-coding gene in the species Homo sapiens
that may contribute to the cell's response to oxidative stress. Galectin-3 (AGE-R3):Galectin-3 is a lectin that binds AGEs and facilitates their removal from
RAGE_(receptor)
Type of programmed cell death
This phenomenon is promoted by secretion of galectin-13 during ferroptosis. Mechanistically, galectin-13 binds to CD44, inhibiting CD44-mediated membrane
Ferroptosis
Glycoprotein spike on a viral capsid or viral envelope
called CEACAM1. The NTD has a galectin-like protein fold, but binds sugar molecules somewhat differently than galectins. The observed binding of N-acetylneuraminic
Coronavirus_spike_protein
Potassium channel
involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States
ROMK
Species of mushroom
of P. pulmonarius may slow the proliferation of cancer cells with high galectin-3 levels, while at the same time downregulate tumour cell adherence – which
Pleurotus_pulmonarius
Species of bivalve
Ni et al. 2007 and is the first bivalve PGRP to be cloned. AiGal1 is a galectin discovered by Song et al. 2010, CfToll-1 is a toll-like receptor (TLR)
Argopecten_irradians
Protein-coding gene in the species Homo sapiens
Grabski S, Wang JL, Patterson RJ (September 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic
Gem-associated_protein_4
Family of fluorescent dyes
2011). "Fungal Recognition is Mediated by the Association of Dectin-1 and Galectin-3 in Macrophages". Proc. Natl. Acad. Sci. U.S.A. 108 (34): 14270–14275
Alexa_Fluor
Short peptide present at N-terminal of newly synthesized proteins
peptides can also be secreted by unconventional mechanisms. E.g. Interleukin, Galectin. The process by which such secretory proteins gain access to the cell exterior
Signal_peptide
Biological analysis approach
Berhane; Schwartz, Stanley A. (February 2025). "Omics analysis reveals galectin-3 to be a potential key regulator of allergic inflammation in hereditary
Multiomics
Regulators of the immune system
Th1/Tc1 function by triggering cell death upon interaction with its ligand, galectin-9. VISTA: Short for V-domain Ig suppressor of T cell activation, VISTA
Immune_checkpoint
Signal to activate immune cells
expressed mainly on T cells, but also on NK cells. Due to extracellular galectin 9 binding, 41-BB complexes are kept preassembled on the membrane. It interacts
Co-stimulation
inflammatory immune cells like macrophages can release a protein called galectin-3, which causes mural cells to multiply and produce procollagen 1—a precursor
Mural_cell
Diseases caused by abnormal protein structure
Lomas DA (July 1997). "Conformational disease". Lancet. 350 (9071): 134–8. doi:10.1016/S0140-6736(97)02073-4. PMID 9228977. S2CID 39124185. Westermark
Proteinopathy
Protein-coding gene in humans
motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin". Molecular Biology of the Cell. 15 (8): 3580–90. doi:10.1091/mbc.E04-03-0236
CSPG4
Immune response to yeast
Chemically Induced Colitis and Augments Inflammatory Responses through Galectin-3". The Journal of Infectious Diseases. 197 (7): 972–980. doi:10.1086/528990
Anti–Saccharomyces cerevisiae antibody
Anti–Saccharomyces_cerevisiae_antibody
Protein-coding gene in the species Homo sapiens
Grabski S, Wang JL, Patterson RJ (September 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic
Gem-associated_protein_2
Medical condition
Papotti M, Rodriguez J, De Pompa R, Bartolazzi A, Rosai J (April 2005). "Galectin-3 and HBME-1 expression in well-differentiated thyroid tumors with follicular
Papillary_thyroid_cancer
Mammalian protein found in humans
reducing β-catenin nuclear accumulation is via the inhibition of galectin-3. The galectin-3 inhibitor GR-MD-02 is currently undergoing clinical trials in
Catenin_beta-1
American doctor (born 1941)
ISSN 0036-8075. S2CID 153488170. "Biography Gilbert S. Omenn, M.D., Ph.D". Galectin Therapeutics Inc. Retrieved 26 October 2021. Barnes, Steve (February 24
Gil_Omenn
Protein-coding gene in humans
is mediated by interactions between LAMP1 and LAMP2 and E-selectin and galectins, with the LAMPs serving as ligands for the cell-adhesion molecules. Cell
LAMP1
Protein found in humans
involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States
Fibroblast_growth_factor_23
heme oxygenase 1, HLA-G, CD95L, TNF-related apoptosis inducing ligands, galectin-1 and DC-SIGN and production of immunosuppressive molecules such as IL-10
Tolerogenic_dendritic_cell
When dysfunction of the kidneys or heart induces dysfunction in the other
the diagnosis of CRS. Though less frequently used in clinical practice, Galectin-3 and ST2 (suppressor of tumorigenicity 2), markers of fibrosis and myocardial
Cardiorenal_syndrome
Protein-coding gene in the species Homo sapiens
Cox AD, Kloog Y (February 2013). "Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis". Oncotarget. 4 (2): 256–268
Jun_dimerization_protein_2
Protein-coding gene in humans
"Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas". Cancer Sci. 94 (5): 425–30
CDH17
Protein-coding gene in the species Homo sapiens
Yunis R, Mak SK, et al. (2005). "Nek8 mutation causes overexpression of galectin-1, sorcin, and vimentin and accumulation of the major urinary protein in
NEK8
Insoluble protein aggregate with a fibrillar morphology
hallmark of amyloid structure. Amyloid fibrils are generally composed of 1–8 protofilaments (one protofilament also corresponding to a fibril is shown
Amyloid
Protein found in humans
Hirashima M, Podack ER, Rouse BT (Oct 2012). "TNFRSF25 agonistic antibody and galectin-9 combination therapy controls herpes simplex virus-induced immunoinflammatory
Death_receptor_3
Protein-coding gene in the species Homo sapiens
metastatic ones. LAMP2, along with LAMP1, interact with E-selectin and galectins to mediate the adhesion of some cancer cells to the ECM. The two LAMP
LAMP2
Technology used to validate protein interactions
V., Inohara, H. & Raz, A. Importin-mediated nuclear translocation of galectin-3. J. Biol. Chem. 281, 39649-39659 (2006). Liu, H. et al. Mutual regulation
Bimolecular fluorescence complementation
Bimolecular_fluorescence_complementation
Office site in Edinburgh, Scotland
Edinburgh Bioquarter. 9 June 2020. Retrieved 26 July 2022. "Galecto develops galectin modulators | Case Study". Edinburgh Bioquarter. 3 December 2020. Retrieved
Edinburgh_BioQuarter
Protein-coding gene in the species Homo sapiens
1016/S0021-9258(18)88883-4. PMID 3997857. Magnaldo T, Bernerd F, Darmon M (1995). "Galectin-7, a human 14-kDa S-lectin, specifically expressed in keratinocytes and
SERPINE2
Protein-coding gene in the species Homo sapiens
involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States
TRPV5
Mammalian protein found in Homo sapiens
ARSB leads to increase in free galectin-3, which attaches more strongly to less sulfated chondroitin 4-sulfate. Galectin-3 then acts on transcription factors
Arylsulfatase_B
Member of the interleukin 1 receptor family
biomarkers such as BNP, NT-proBNP, highly sensitive troponin, GDF-15, and galectin-3. One study indicated that discrimination is independent of age, body
ST2_cardiac_biomarker
French-German biochemist (born 1966)
Lamaze C, Loew D, Shevchenko A, Gaus K, Parton RG, Johannes L (2014) Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent
Ludger_Johannes
Australian asthma researcher
Chua JC, Douglass JA, et al. (2012) Galectin-10, a Potential Biomarker of Eosinophilic Airway Inflam. PLoS ONE 7(8): e42549. Thompson BR, Douglass JA,
Jo_Douglass
Proteoglycan; lubricant; gene
water-soluble synovial fluid protein. In synovial fluid it interacts with Galectin-3 that improves its lubricating property. Lubricin's unglycosylated regions
Proteoglycan_4
neurotrophic factor (CNTF), and a soluble carbohydrate-binding protein, Galectin-1, are reported as factors that maintain such properties of NSC in stem
Endogenous_regeneration
Indian molecular biologist and biophysicist
(September 2000). "Elucidation of the mechanism of interaction of sheep spleen galectin-1 with splenocytes and its role in cell–matrix adhesion". Journal of Molecular
Sunil_Kumar_Podder
Glycomics research initiative
major classes of mammalian glycan-binding proteins (GBPs): C-type lectin, galectin, and SIGLEC immune receptors that bind carbohydrates: CD1, T cell receptor
Consortium for Functional Glycomics
Consortium_for_Functional_Glycomics
Mammalian protein found in humans
membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". Journal of Immunology. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7
CD7
Glycoproteins found in plant cell walls
proteins contain both GalT and galectin domains, while Clade 10 proteins contain a GalT-specific domain. The galectin domain is proposed to allow the
Arabinogalactan_protein
(February 2021). "Ultrasound‑targeted microbubble destruction‑mediated Galectin‑7‑siRNA promotes the homing of bone marrow mesenchymal stem cells to alleviate
Clinical uses of mesenchymal stem cells
Clinical_uses_of_mesenchymal_stem_cells
Protein-coding gene in the species Homo sapiens
and member of the tetraspanin superfamily, joins the list of ligands of galectin-3". BMC Cell Biol. 2 17. doi:10.1186/1471-2121-2-17. PMC 48140. PMID 11532191
LIM2
Human protein
rhodocytin (a platelet-activating snake venom also termed aggretin), hemin, galectin-9, dextran sulfate, sulfated polysaccharides, fucoidan, ketacine (i.e.
PDPN
Class of biological intermolecular interactions
Common oligomerization structures of lectins are shown below. For example, galectins are usually observed as dimers, while intelectins form trimers and pentraxins
Glycan–protein_interaction
Mammalian protein found in humans
evaluation of treatment response in classical Hodgkin lymphoma: comparison of sGalectin-1, sCD163 and sCD30 with TARC". British Journal of Haematology. 175 (5):
CCL17
Canadian cell biologist
including Lipid raft, caveolae, non-caveolar caveolin-1 scaffolds, and the galectin lattice, elucidating their regulation of cancer cell signaling and migration
Ivan_R._Nabi
Protein-coding gene in the species Homo sapiens
high-confidence interacting proteins (HCIPs) by CompPASS-Plus. Also known as galectin-3 (Gal3), LGALS3 participates in various cellular functions including apoptosis
SLC46A3
Protein-coding gene in the species Homo sapiens
SJ, Zheng XX, Strom TB, Kuchroo VK (December 2005). "The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity". Nature Immunology. 6
HAVCR1
Species of virus
N-terminal domain (NTD) of the spike protein of coronavirus is similar to galectin in animal cells. Therefore, it has been suggested that this domain was
Murine_coronavirus
Tumour-promoting cell type
high expression of checkpoint molecules such as PD-L1, PD-L2, B7-H3/H4, galectins and the enzyme IDO. CAFs in pancreatic cancer upregulate PD-1, CTLA-4
Cancer-associated_fibroblast
Protein-coding gene in the species Homo sapiens
(2002). "Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation"
Annexin_A7
Simultaneous measurement of spectra and pictures
Function. Molecular and Cellular Biology (2008) 4377–4385. Belanis L, et al., Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters
Chemical_imaging
Indian chemist
and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists: Vishal Kumar Rajput, Hakon Leffler, Ulf J. Nilsson and Balaram
Balaram_Mukhopadhyay
Protein-coding gene in the species Homo sapiens
Grabski S, Wang JL, Patterson RJ (Sep 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic
Small nuclear ribonucleoprotein D1
Small_nuclear_ribonucleoprotein_D1
A kind of tumor
However, only pilocytic astrocytomas and ependymomas stain positively for Galectin-3. The subtype of ependymoma can also be narrowed down by molecular means
Pediatric_ependymoma
negatively selected to undergo apoptosis. The molecules like gal-3 (Galectin-3) and gal-1(Galectin-1), on the other hand, produce antagonistic effects. They inhibit
Thymic_nurse_cell
Mammalian protein found in humans
membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". J. Immunol. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7.3801. PMID 10490978
CD43
Mammalian protein found in Homo sapiens
malignant follicular thyroid nodules. In conjunction with cyclin A and galectin-3, hexokinase III could be used as diagnostic biomarker to screen for malignancy
Hexokinase_III
GALECTIN 8
GALECTIN 8
Surname or Lastname
English (also found in Wales)
English (also found in Wales) : patronymic from the Middle English personal name Jenk, a back-formation from Jenkin with the removal of the supposed Anglo-Norman French diminutive suffix -in.Joseph Jenks (1602–83), the descendant of an old Welsh family, was born in England and traveled to Saugus, near Lynn, MA, in 1642 to assist in the development of America’s first iron works. His son, Joseph Jenckes (sic), followed in 1650, founded Pawtucket, RI, and raised four sons who held places of respect and distinction in RI, including one who served as governor for five years.
Male
Swedish
 Swedish form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.
Surname or Lastname
English
English : habitational name from any of various places, for example in Devon, Dorset, Essex, Kent, and Warwickshire, so named from Old English lang, long ‘long’ + dūn ‘hill’.Samuel Langdon, Harvard College president in 1774–80, was born in Boston, MA, in 1723 but lived out his years in Hampton Falls, NH. Three of his children left descendants. His grandfather Philip (b. 1646) had came from Braunton in Devon, England, and was married in Andover, Essex Co., MA, in 1684, according to family historians.
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : via Old French from the Germanic personal name Milo, of unknown etymology. The name was introduced to England by the Normans in the form Miles (oblique case Milon). In English documents of the Middle Ages the name sometimes appears in the Latinized form Milo (genitive Milonis), although the normal Middle English form was Mile, so the final -s must usually represent the possessive ending, i.e. ‘son or servant of Mile’.English : patronymic from the medieval personal name Mihel, an Old French contracted form of Michael.English : occupational name for a servant or retainer, from Latin miles ‘soldier’, sometimes used as a technical term in this sense in medieval documents.Irish (County Mayo) : when not the same as 1 or 3, an Anglicized form of Gaelic Ó Maolmhuire, Myles being used as the English equivalent of the Gaelic personal name Maol Muire (see Mullery).Jewish (eastern Ashkenazic) : unexplained.Dutch : variant of Miels, a variant of Miele 3.John Miles or Myles (c.1621–83), born probably in Herefordshire, England, was a pioneer American Baptist minister who emigrated to New England in 1662 and had a pastorate in Swansea, MA. Many of his descendants spell their name Myles.
Surname or Lastname
English
English : from the personal name Horace, Latin Horatius, a Roman family name of unknown origin, associated chiefly with the name of the poet Quintus Horatius Flaccus (65–8 bc).
Boy/Male
American, Australian, Basque, Chinese, Finnish, French, German, Latin, Spanish, Swedish
Healthy; Strong; Valiant; The Name of More than 50 Saints and Three Roman Emperors
Surname or Lastname
English
English : habitational name from any of several places so called, named with the genitive plural huntena of Old English hunta ‘hunter’ + tūn ‘enclosure’, ‘settlement’ or dūn ‘hill’ (the forms in -ton and -don having become inextricably confused). A number of bearers of this name may well derive it from Huntingdon, now in Cambridgeshire (formerly the county seat of the old county of Huntingdonshire), which is named from the genitive case of Old English hunta ‘huntsman’, perhaps used as a personal name, + dūn ‘hill’.A prominent American family of this name were founded by Simon Huntington, who himself never saw the New World, for he died in 1633 on the voyage to Boston, where his widow settled with her children. Their descendants include Jabez Huntington (1719–86), a wealthy West Indies trader, and Samuel Huntington (1731–96), who was one of the signers of the Declaration of Independence. Collis Potter Huntington (1821–1900) was an American railway magnate. Beginning with little education or money, he made a huge fortune, some of which he left to his nephew, Henry Huntington (1850–1927), who used the money to establish the Huntington library and art gallery in CA.
Male
German
 German form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.
Female
English
Feminine form of French Valentin, VALENTINE means "healthy, strong." Compare with masculine Valentine.
Surname or Lastname
Scottish (common in the Northern Isles)
Scottish (common in the Northern Isles) : patronymic from the personal name Magnus.English : patronymic from the Middle English nickname or byname Mann.Jewish (Ashkenazic) : patronymic from Man 8.
Surname or Lastname
English and Scottish
English and Scottish : occupational name for a stonemason, Middle English, Old French mas(s)on. Compare Machen. Stonemasonry was a hugely important craft in the Middle Ages.Italian (Veneto) : from a short form of Masone.French : from a regional variant of maison ‘house’.George Mason (1725–92), the American colonial statesman who framed the VA Bill of Rights and Constitution, which was used as a model by Thomas Jefferson when drafting the Declaration of Independence, was a VA planter, fourth in descent from George Mason (?1629–?86), a royalist soldier of the English Civil War who had received land grants in VA. As well as being prominent in the affairs of VA, the family also produced the first governor of MI.
Surname or Lastname
English
English : variant of Leet.An early American bearer of this name was one of the founders of Guilford, CT. William Leete (c. 1613–83), a colonial governor of New Haven colony and CT, was born at Dodington, Huntingtonshire, England. He converted to Puritanism and sailed for America to escape persecution in May 1639.
Surname or Lastname
English
English : from the Middle English vernacular form, Maudeleyn, of the New Testament Greek personal name Magdalēnē. This is a byname, meaning ‘woman from Magdala’ (a village on the Sea of Galilee, deriving its name from Hebrew migdal ‘tower’), denoting the woman cured of evil spirits by Jesus (Luke 8:2), who later became a faithful follower. In Christian folk belief she was generally identified with the repentant sinner who washed Christ’s feet with her tears in Luke 7; hence the name came to be used as a byname for a prostitute, also a tearful woman. The popularity of the personal name increased with the supposed discovery of her relics in the 13th century.
Surname or Lastname
English
English : variant spelling of Hain 1–3.Isaac Hayne (1745–81) was an American revolutionary militia officer, executed by the British for breaking parole. He owned an ironworks and was manufacturing ammunition for the American forces when he was caught. His grandfather had emigrated from England to SC in about 1700.
Boy/Male
Swedish American Latin Spanish
Brave.
Male
French
 French form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.
Male
Danish
, healthy.
Surname or Lastname
English
English : from a Norman personal name, Leodegar, Old French Legier, of Germanic origin, composed of the elements liut ‘people’, ‘tribe’ + gÄr, gÄ“r ‘spear’. The name was borne by a 7th-century bishop of Autun, whose fame contributed to the popularity of the name in France. (In Germany the name was connected with a different saint, an 8th-century bishop of Münster.)English : variant of Letcher, in part a deliberate alteration to avoid the association with Middle English lecheor ‘lecher’.
Surname or Lastname
English
English : nickname for a tall (Middle English long ‘long’) person who was a good companion (felagh, felaw ‘partner’, ‘comrade’).The name made famous in America by poet Henry Wadsworth Longfellow (1807–82) of Portland, ME, was introduced to North America by William Longfellow of Yorkshire, England, who settled in Newbury, MA, about 1676.
Surname or Lastname
English
English : variant of Liddiard.Revolutionary soldier William Ledyard was born at Groton, CT, in 1738, a descendant of John Ledyard who sailed from Bristol, England, and settled in CT. The celebrated traveler John Ledyard (1751–89) was William’s nephew and was also born in Groton.
GALECTIN 8
GALECTIN 8
Boy/Male
Indian, Sanskrit
Victorious
Boy/Male
Assamese, Hindu, Indian, Marathi, Sanskrit, Telugu
Ornament
Male
English
Variant spelling of English Matthias, MATHIAS means "gift of God."
Male
English
English occupational surname transferred to forename use, which could have derived from any of the following: 1) Middle English foster, FOSTER means "foster-parent," 2) forster, meaning "forester," 3) forster, meaning "shearer," or 4) fuyster, meaning "saddle-tree maker."
Girl/Female
Hindu
Chant
Girl/Female
American, Anglo, Arabic, Australian, British, Danish, English, Hebrew, Italian, Latin
Fruitful Desert Flower; Of Noble Birth; Royal; Noble Woman; Sabrina; Princess; A Legendary Goddess
Girl/Female
Muslim/Islamic
Resembling the full moon
Biblical
his kingdom; his counselor
Girl/Female
Latin
Earth.
Girl/Female
Indian, Punjabi, Sikh
Golden Love
GALECTIN 8
GALECTIN 8
GALECTIN 8
GALECTIN 8
GALECTIN 8
a.
In the duodecimal system of mensuration, the twelfth part of an inch or prime; a line. See Inch, and Prime, n., 8.
a.
Of or pertaining to milk; got from milk; as, galactic acid.
a.
Of or pertaining to the galaxy or Milky Way.
n.
See Web, n., 8.
n.
An amorphous, gelatinous substance containing nitrogen, found in milk and other animal fluids. It resembles peptone, and is variously regarded as a coagulating or emulsifying agent.
n.
A popular Italian dance in quick 3-4 or 6-8 time, running mostly in triplets, but with a hop step at the beginning of each measure. See Tarantella.
n.
Hence, any post or stone marking a boundary; a term. See Term, 8.
a.
Somewhat resembling the Roman; -- applied sometimes to the debased style of the later Roman empire, but esp. to the more developed architecture prevailing from the 8th century to the 12th.
n.
A rare metallic element of the boron-aluminium group, found in gadolinite and other rare minerals, and extracted as a dark gray powder. Symbol Y. Atomic weight, 89.
prep.
As sign of the infinitive, to had originally the use of last defined, governing the infinitive as a verbal noun, and connecting it as indirect object with a preceding verb or adjective; thus, ready to go, i.e., ready unto going; good to eat, i.e., good for eating; I do my utmost to lead my life pleasantly. But it has come to be the almost constant prefix to the infinitive, even in situations where it has no prepositional meaning, as where the infinitive is direct object or subject; thus, I love to learn, i.e., I love learning; to die for one's country is noble, i.e., the dying for one's country. Where the infinitive denotes the design or purpose, good usage formerly allowed the prefixing of for to the to; as, what went ye out for see? (Matt. xi. 8).
n.
The jack. See 2d Jack, 8. (c).
a.
Woven in such a way as to produce an effect of variegation, of changeable tints, or of being figured; as, shot silks. See Shoot, v. t., 8.
n.
An office or feast celebrated with less solemnity than the double ones. See Double, n., 8.
n.
One of the primary planets. It is about 1,800,000,000 miles from the sun, about 36,000 miles in diameter, and its period of revolution round the sun is nearly 84 of our years.
n.
A South American animal of the family Mustelidae (Galictis vittata). It is about two feet long, exclusive of the tail. Its under parts are black. Also called South American glutton.
n.
A kind of package in which pepper and other dry commodities are sometimes exported from the East Indies. The robbin of rice in Malabar weighs about 84 pounds.
n.
A white waxy substance found in the sap of the South American cow tree (Galactodendron).
n.
A rare metallic element. It occurs quite widely, but in small quantities, and always combined. It is isolated as a soft yellowish white metal, analogous to potassium in most of its properties. Symbol Rb. Atomic weight, 85.2.
n.
An alloy of copper and zinc, resembling brass, and containing about 84 per cent of copper; -- called also German, / Dutch, brass. It is very malleable and ductile, and when beaten into thin leaves is sometimes called Dutch metal. The addition of arsenic makes white tombac.
n.
An amorphous, gummy carbohydrate resembling gelose, found in the seeds of leguminous plants, and yielding on decomposition several sugars, including galactose.