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Protein family binding to β-galactoside sugars
Galectins are a class of proteins that bind specifically to β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which
Galectin
Protein-coding gene in the species Homo sapiens
Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating
Galectin-4
Protein found in humans
Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene. This gene encodes a member of the galectin family. Galectins
Galectin-8
Class of peptides that have antimicrobial activity
Al-Dhabi NA, Arockiaraj J (June 2017). "Bactericidal activity of fish galectin 4 derived membrane-binding peptide tagged with oligotryptophan". Developmental
Antimicrobial_peptides
Protein-coding gene in the species Homo sapiens
Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have
Galectin-3
Protein-coding gene in the species Homo sapiens
Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. LGALS1 contains four exons. The galectin-1 protein is 135 amino acids in length and
Galectin-1
Protein-coding gene in the species Homo sapiens
Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9
Galectin-9
Property of chemical species that can form multiple bonds
domain-I of recombinant tandem-repeat-type galectin-4 from rat gastrointestinal tract (G4-N)". Biochimie. 86 (4–5): 317–326. doi:10.1016/j.biochi.2004.03
Polyvalency_(chemistry)
Protein-coding gene in humans
Galectin-10 is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional
CLC_(gene)
Protein-coding gene in the species Homo sapiens
Placental protein 13 (PP13, also known as galectin-13) is a protein that in humans is encoded by the LGALS13 gene. It is composed of two identical subunits
LGALS13
Pharmaceutical compound
Belapectin (also known as GR-MD-02) is a galectin-3 inhibitor developed by Galectin Therapeutics for the treatment of non-alcoholic steatohepatitis. In
Belapectin
Protein-coding gene in the species Homo sapiens
Galectin-2 is a protein that in humans is encoded by the LGALS2 gene. The protein encoded by this gene is a soluble beta-galactoside binding lectin. The
Galectin-2
chemoattractant protein-1 MeSH D12.776.467.374.200.700 – platelet factor 4 MeSH D12.776.467.374.200.750 – rantes MeSH D12.776.467.374.400.442 – hematopoietic
List_of_MeSH_codes_(D12.776)
Protein-coding gene in the species Homo sapiens
Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding lectins involved in modulating
Galectin-7
American neurosurgeon and government official (born 1951)
July 1, 2013. In 2021, Carson joined Galectin Therapeutics to assist with development of the company's galectin-3 inhibitor, belapectin, as a treatment
Ben_Carson
Proteoglycan; lubricant; gene
water-soluble synovial fluid protein. In synovial fluid it interacts with Galectin-3 that improves its lubricating property. Lubricin's unglycosylated regions
Proteoglycan_4
Protein-coding gene in the species Homo sapiens
Grabski S, Wang JL, Patterson RJ (September 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic
Gem-associated_protein_4
Process of cells digesting parts of themselves
involved in response to lysosomal damage, often directed by galectins such as galectin-3 and galectin-8. Repair of damaged DNA involves the recruitment of enzymes
Autophagy
Precursor cells of neurons and glia during embryonic development
59 (4): 558–65. doi:10.4103/0028-3886.84338. PMID 21891934. Sakaguchi, M; Okano, H (2012). "Neural stem cells, adult neurogenesis, and galectin-1: From
Neural_stem_cell
American business people
spa, and gift shops. Richard Uihlein is the chairman of the board for Galectin Therapeutics, a publicly traded biotech company focusing on treatments
Richard_and_Elizabeth_Uihlein
Chemical compound
Selvigaltin (GB1211) is the first small-molecule, orally delivered galectin-3 inhibitor to be discovered. It is developed by Galecto Biotech, which is
Selvigaltin
Argentine biochemist
how such tumors can be regressed. He also looked at the properties of galectins, and how they show potential for disease. Rabinovich was born in Córdoba
Gabriel_A._Rabinovich
Protein-coding gene in the species Homo sapiens
glycan-binding sites is recognizes by carbohydrate domain of another ligands galectin-9 (Gal-9). The mucin domain is variable in a member of the TIM family,
HAVCR2
Suborder of fishes
confirmed to be within the venom are cystatins, peroxiredoxin and galectin. Galectin induces cell death in its victims and cystatins inhibit defense enzymes
Stingray
Mammalian protein found in Homo sapiens
alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)". Hadari YR, Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (2000). "Galectin-8 binding
Integrin_alpha_4
Andrea; Carpi, Federico; Mechanick, Jeffrey I.; Bartolazzi, Armando (2010). "Galectin-3 detection on large-needle aspiration biopsy improves preoperative selection
List_of_statistical_tests
Protein-coding gene in the species Homo sapiens
Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene. The galectins are a family of beta-galactoside-binding proteins
LGALS3BP
Mammalian protein found in humans
At the heart of GALTOR is galectin-8, a member of β-galactoside binding superfamily of cytosolic lectins termed galectins, which recognizes lysosomal
MTOR
Human chromosome
thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit HSPC159: Galectin-related protein ID2-AS1: encoding protein Id2 antisense rna 1 (head to
Chromosome_2
Group of immune cells in the bone marrow
evidence for inhibiting Galectin-3 as a therapeutic target to reduce MDSCs. In a Phase 1b clinical trial of GR-MD-02 developed by Galectin Therapeutics, investigators
Myeloid-derived suppressor cell
Myeloid-derived_suppressor_cell
Cytokine protein
been shown to interact with interleukin-6 receptor, glycoprotein 130, and Galectin-3. There is considerable functional overlap and interaction between Substance
Interleukin_6
Class of enzymes
MH, Kimura T, et al. (October 2016). "TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis"
AMP-activated_protein_kinase
Defense mechanism of tumors against immunity
proteins that can deliver death signals in leukocytes (Fas ligand and galectin-1). The formation of a leukocyte infiltrate at places of inflammation is
Endothelial_cell_anergy
Type of breast cancer lacking certain gene expressions
glycolysis in these tumors is probably related to their aggressive biology. Galectin-1 in TNBC is a beta-galactosidase-binding protein that shields cancer cells
Triple-negative_breast_cancer
Protein-coding gene in the species Homo sapiens
that may contribute to the cell's response to oxidative stress. Galectin-3 (AGE-R3):Galectin-3 is a lectin that binds AGEs and facilitates their removal from
RAGE_(receptor)
Species of virus
PMC 5457962. PMID 27578435. BCoV S1-NTD does not recognize galactose as galectins do. Instead, it recognizes 5-N-acetyl-9-O-acetylneuraminic acid (Neu5
Human_coronavirus_OC43
Antibody isotype
Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44". Immunity. 49 (4): 709–724.e8. doi:10.1016/j.immuni.2018.08.013. ISSN 1074-7613
Immunoglobulin_D
Glycoprotein spike on a viral capsid or viral envelope
called CEACAM1. The NTD has a galectin-like protein fold, but binds sugar molecules somewhat differently than galectins. The observed binding of N-acetylneuraminic
Coronavirus_spike_protein
Type of endocrine gland cancer
approach involves the use of immunotherapy, such as oncolytic viruses. Galectin-specific mechanisms of the tumor microenvironment are under study. Because
Pancreatic_cancer
Short peptide present at N-terminal of newly synthesized proteins
peptides can also be secreted by unconventional mechanisms. E.g. Interleukin, Galectin. The process by which such secretory proteins gain access to the cell exterior
Signal_peptide
Species of mushroom
of P. pulmonarius may slow the proliferation of cancer cells with high galectin-3 levels, while at the same time downregulate tumour cell adherence – which
Pleurotus_pulmonarius
Potassium channel
involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States
ROMK
Species of bivalve
Ni et al. 2007 and is the first bivalve PGRP to be cloned. AiGal1 is a galectin discovered by Song et al. 2010, CfToll-1 is a toll-like receptor (TLR)
Argopecten_irradians
Family of fluorescent dyes
2011). "Fungal Recognition is Mediated by the Association of Dectin-1 and Galectin-3 in Macrophages". Proc. Natl. Acad. Sci. U.S.A. 108 (34): 14270–14275
Alexa_Fluor
Stinging cell used by cnidarians
composed of polymerized NOWA (Nematocyst Outer Wall Antigen) proteins. Nemato Galectin, minicollagen Ncol-15 and chondroitin are novel proteins used to build
Cnidocyte
Biological analysis approach
Berhane; Schwartz, Stanley A. (February 2025). "Omics analysis reveals galectin-3 to be a potential key regulator of allergic inflammation in hereditary
Multiomics
Signal to activate immune cells
expressed mainly on T cells, but also on NK cells. Due to extracellular galectin 9 binding, 41-BB complexes are kept preassembled on the membrane. It interacts
Co-stimulation
Regulators of the immune system
Th1/Tc1 function by triggering cell death upon interaction with its ligand, galectin-9. VISTA: Short for V-domain Ig suppressor of T cell activation, VISTA
Immune_checkpoint
Type of programmed cell death
This phenomenon is promoted by secretion of galectin-13 during ferroptosis. Mechanistically, galectin-13 binds to CD44, inhibiting CD44-mediated membrane
Ferroptosis
Mammalian protein found in Homo sapiens
Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (July 2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". J
Integrin_alpha_3
His group discovered a new pathway of cell-autonomous defence relying on galectin-8 as the receptor for membrane damage caused by cytosol-invading bacteria
Felix_Armin_Randow
Mammalian protein found in Homo sapiens
Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (Jul 2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". Journal
Integrin_beta_1
Mammalian protein found in humans
reducing β-catenin nuclear accumulation is via the inhibition of galectin-3. The galectin-3 inhibitor GR-MD-02 is currently undergoing clinical trials in
Catenin_beta-1
inflammatory immune cells like macrophages can release a protein called galectin-3, which causes mural cells to multiply and produce procollagen 1—a precursor
Mural_cell
Protein-coding gene in humans
promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin". Molecular Biology of the Cell. 15 (8): 3580–90
CSPG4
Protein complex
lumen. Under homeostatic conditions, Galectin-8 associates with active mTOR. Following membrane damage, galectin-8 switches from mTOR to complexes containing
MTORC1
Protein-coding gene in humans
is mediated by interactions between LAMP1 and LAMP2 and E-selectin and galectins, with the LAMPs serving as ligands for the cell-adhesion molecules. Cell
LAMP1
Protein found in humans
involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States
Fibroblast_growth_factor_23
Diseases caused by abnormal protein structure
LeVine H (2000). "The cerebral proteopathies". Neurobiology of Aging. 21 (4): 559–61. doi:10.1016/S0197-4580(00)00160-3. PMID 10924770. S2CID 54314137
Proteinopathy
Mammalian protein found in Homo sapiens
ARSB leads to increase in free galectin-3, which attaches more strongly to less sulfated chondroitin 4-sulfate. Galectin-3 then acts on transcription factors
Arylsulfatase_B
When dysfunction of the kidneys or heart induces dysfunction in the other
the diagnosis of CRS. Though less frequently used in clinical practice, Galectin-3 and ST2 (suppressor of tumorigenicity 2), markers of fibrosis and myocardial
Cardiorenal_syndrome
Immune response to yeast
Chemically Induced Colitis and Augments Inflammatory Responses through Galectin-3". The Journal of Infectious Diseases. 197 (7): 972–980. doi:10.1086/528990
Anti–Saccharomyces cerevisiae antibody
Anti–Saccharomyces_cerevisiae_antibody
Insoluble protein aggregate with a fibrillar morphology
There are two characteristic scattering diffraction signals produced at 4.7 and 10 Å (0.47 nm and 1.0 nm), corresponding to the interstrand and stacking
Amyloid
DNA-like molecule in the human body
Barbashov S, Kawano T, Kharbanda S, Kufe D (September 2007). "The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop". Molecular
Mir-322 microRNA precursor family
Mir-322_microRNA_precursor_family
Medical condition
Papotti M, Rodriguez J, De Pompa R, Bartolazzi A, Rosai J (April 2005). "Galectin-3 and HBME-1 expression in well-differentiated thyroid tumors with follicular
Papillary_thyroid_cancer
heme oxygenase 1, HLA-G, CD95L, TNF-related apoptosis inducing ligands, galectin-1 and DC-SIGN and production of immunosuppressive molecules such as IL-10
Tolerogenic_dendritic_cell
American geneticist
damage: GALTOR (galectin-8–mTOR) links endomembrane damage to autophagy, galectin-3 recruits ESCRTs for lysosome repair, and galectin-9 activates AMPK
Vojo_Deretic
Protein-coding gene in the species Homo sapiens
metastatic ones. LAMP2, along with LAMP1, interact with E-selectin and galectins to mediate the adhesion of some cancer cells to the ECM. The two LAMP
LAMP2
American doctor (born 1941)
ISSN 0036-8075. S2CID 153488170. "Biography Gilbert S. Omenn, M.D., Ph.D". Galectin Therapeutics Inc. Retrieved 26 October 2021. Barnes, Steve (February 24
Gil_Omenn
Technology used to validate protein interactions
V., Inohara, H. & Raz, A. Importin-mediated nuclear translocation of galectin-3. J. Biol. Chem. 281, 39649-39659 (2006). Liu, H. et al. Mutual regulation
Bimolecular fluorescence complementation
Bimolecular_fluorescence_complementation
Protein found in humans
Hirashima M, Podack ER, Rouse BT (Oct 2012). "TNFRSF25 agonistic antibody and galectin-9 combination therapy controls herpes simplex virus-induced immunoinflammatory
Death_receptor_3
American pediatric surgeon
curing spina bifida. In 2019, Farmer and Aijun Wang identified exosomes and galectin 1 as key to protecting neurons and ultimately reducing the lower-limb paralysis
Diana_L._Farmer
Member of the interleukin 1 receptor family
biomarkers such as BNP, NT-proBNP, highly sensitive troponin, GDF-15, and galectin-3. One study indicated that discrimination is independent of age, body
ST2_cardiac_biomarker
Protein-coding gene in the species Homo sapiens
7029–34. doi:10.1016/S0021-9258(18)88883-4. PMID 3997857. Magnaldo T, Bernerd F, Darmon M (1995). "Galectin-7, a human 14-kDa S-lectin, specifically expressed
SERPINE2
Protein-coding gene in the species Homo sapiens
involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States
TRPV5
Protein-coding gene in the species Homo sapiens
2013). "Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis". Oncotarget. 4 (2): 256–268. doi:10.18632/oncotarget
Jun_dimerization_protein_2
Prevalent tubulovesicular membranes
subunits and causes a bending of the membrane. Proteins like galectin-3, galectin 8, and GSL-dependent cellular endocytosis of CD166 are all known
Clathrin-independent endocytosis
Clathrin-independent_endocytosis
Protein-coding gene in the species Homo sapiens
and member of the tetraspanin superfamily, joins the list of ligands of galectin-3". BMC Cell Biol. 2 17. doi:10.1186/1471-2121-2-17. PMC 48140. PMID 11532191
LIM2
Mammalian protein found in humans
membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". Journal of Immunology. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7
CD7
Protein-coding gene in the species Homo sapiens
SJ, Zheng XX, Strom TB, Kuchroo VK (December 2005). "The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity". Nature Immunology. 6
HAVCR1
Protein-coding gene in the species Homo sapiens
overexpression of galectin-1, sorcin, and vimentin and accumulation of the major urinary protein in renal cysts of jck mice". Mol. Cell. Proteomics. 4 (7): 1009–18
NEK8
Mammalian protein found in humans
evaluation of treatment response in classical Hodgkin lymphoma: comparison of sGalectin-1, sCD163 and sCD30 with TARC". British Journal of Haematology. 175 (5):
CCL17
French-German biochemist (born 1966)
Lamaze C, Loew D, Shevchenko A, Gaus K, Parton RG, Johannes L (2014) Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent
Ludger_Johannes
Human protein
rhodocytin (a platelet-activating snake venom also termed aggretin), hemin, galectin-9, dextran sulfate, sulfated polysaccharides, fucoidan, ketacine (i.e.
PDPN
Simultaneous measurement of spectra and pictures
Function. Molecular and Cellular Biology (2008) 4377–4385. Belanis L, et al., Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters
Chemical_imaging
Tumour-promoting cell type
molecules such as PD-L1, PD-L2, B7-H3/H4, galectins and the enzyme IDO. CAFs in pancreatic cancer upregulate PD-1, CTLA-4 or TIM-3 on both CD4+ and CD8+ T cell
Cancer-associated_fibroblast
Protein-coding gene in the species Homo sapiens
Grabski S, Wang JL, Patterson RJ (Sep 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic
Small nuclear ribonucleoprotein D1
Small_nuclear_ribonucleoprotein_D1
Protein-coding gene in humans
"Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the pancreas". Cancer Sci. 94 (5): 425–30
CDH17
Protein-coding gene in the species Homo sapiens
presence of galectin-3 binding protein, as has been shown in WiDr cells. The authors suggest that the ratio of galectin-3 binding protein to galectin 3 influences
PTPRK
neurotrophic factor (CNTF), and a soluble carbohydrate-binding protein, Galectin-1, are reported as factors that maintain such properties of NSC in stem
Endogenous_regeneration
Species of virus
N-terminal domain (NTD) of the spike protein of coronavirus is similar to galectin in animal cells. Therefore, it has been suggested that this domain was
Murine_coronavirus
Glycoproteins found in plant cell walls
proteins contain both GalT and galectin domains, while Clade 10 proteins contain a GalT-specific domain. The galectin domain is proposed to allow the
Arabinogalactan_protein
Mammalian protein found in humans
Billingsley P, Faust C, et al. (2002). "Cubilin, a binding partner for galectin-3 in the murine utero-placental complex". J. Biol. Chem. 277 (18): 15904–12
Cubilin
A kind of tumor
However, only pilocytic astrocytomas and ependymomas stain positively for Galectin-3. The subtype of ependymoma can also be narrowed down by molecular means
Pediatric_ependymoma
Protein-coding gene in the species Homo sapiens
(2002). "Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation"
Annexin_A7
negatively selected to undergo apoptosis. The molecules like gal-3 (Galectin-3) and gal-1(Galectin-1), on the other hand, produce antagonistic effects. They inhibit
Thymic_nurse_cell
Mammalian protein found in Homo sapiens
malignant follicular thyroid nodules. In conjunction with cyclin A and galectin-3, hexokinase III could be used as diagnostic biomarker to screen for malignancy
Hexokinase_III
Class of biological intermolecular interactions
Common oligomerization structures of lectins are shown below. For example, galectins are usually observed as dimers, while intelectins form trimers and pentraxins
Glycan–protein_interaction
matri-cellular proteins. The up regulation of matri-cellular proteins such as galectin-1, and tenascin-C is present in the stromal tissues of pancreatic cancer
Pancreatic_stellate_cell
Italian physician, immunologist, and academic
Rabinovich, he investigated the extracellular and intracellular functions of galectins and provided insights into mechanisms for controlling cellular processes
Roberto_Paganelli
GALECTIN 4
GALECTIN 4
Surname or Lastname
English (of Norman origin)
English (of Norman origin) : occupational name denoting a servant who carried the ewer to guests at table so that they could wash their hands, Anglo-Norman French and Middle English ewerer (related to ewere ‘jug’), with the French definite article l’.Cornish : variant of Flower 4.
Surname or Lastname
English, Scottish, Irish, French, Dutch, German, Czech, Slovak, Spanish (MartÃn), Italian (Venice), etc.
English, Scottish, Irish, French, Dutch, German, Czech, Slovak, Spanish (MartÃn), Italian (Venice), etc. : from a personal name (Latin Martinus, a derivative of Mars, genitive Martis, the Roman god of fertility and war, whose name may derive ultimately from a root mar ‘gleam’). This was borne by a famous 4th-century saint, Martin of Tours, and consequently became extremely popular throughout Europe in the Middle Ages. As a North American surname, this form has absorbed many cognates from other European forms.English : habitational name from any of several places so called, principally in Hampshire, Lincolnshire, and Worcestershire, named in Old English as ‘settlement by a lake’ (from mere or mær ‘pool’, ‘lake’ + tÅ«n ‘settlement’) or as ‘settlement by a boundary’ (from (ge)mære ‘boundary’ + tÅ«n ‘settlement’). The place name has been charged from Marton under the influence of the personal name Martin.
Surname or Lastname
English and Scottish (of Norman origin) and French
English and Scottish (of Norman origin) and French : habitational name from any of various places in northern France which get their names from the Gallo-Roman personal name Maccius + the locative suffix -acum.English (of Norman origin) : habitational name from Marcy in La Manche. This surname is preserved in the English place name Stondon Massey.English : from a pet form of Matthew.Altered spelling of French Massé (see Masse 4).
Male
French
 French form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.
Surname or Lastname
Scottish and northern English
Scottish and northern English : topographic name for a dweller at the chief farm (or home farm) on an estate, Scottish mains, or a habitational name from any of the various minor places named with this word (originally a shortened form of domain, later associated with the adjective main ‘principal’).English and Scottish : variant of Main 1–4.
Female
English
Feminine form of French Valentin, VALENTINE means "healthy, strong." Compare with masculine Valentine.
Male
Danish
, healthy.
Boy/Male
Swedish American Latin Spanish
Brave.
Male
Swedish
 Swedish form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.
Surname or Lastname
English
English : occupational name for a bookbinder, from Anglo-Norman French liur.English : possibly a topographic name (recorded in 1332 as le Lyghere) for someone who lived in a woodland clearing, from a derivative of Old English lēah ‘woodland clearing’.German : short form of a Germanic personal name formed with liut ‘people’, ‘tribe’ + hari ‘army’.German : possibly a topographic name formed with the element lir ‘swamp’, ‘bog’, or a habitational name from Lier, named with this word.Dutch : habitational name from Lier, in the Belgian province of Antwerp.Norwegian : habitational name from any of numerous farmsteads named with the indefinite plural form of li ‘mountain slope’, ‘hillside’ (see Li 4).
Surname or Lastname
English
English : metronymic from the medieval female personal name Madde, a form of Maud (see Mould 1) or Magdalen (see Maudlin).James Madison (1751–1836), 4th President of the U.S. (1809–17), was born in VA, the son of a planter. He was descended from John Madison, a ship’s carpenter from Gloucester, England, who had settled in VA in about 1653.
Surname or Lastname
English and Scottish
English and Scottish : variant of Carr.Hungarian (Kér) : one of the eight ancient Hungarian tribal names from the Magyar conquest of the Carpathian basin. The Kér tribe, led by a chief called Vata settled in what is now known as Békés county, but King Steven I resettled the tribe in royal estates, far away from their original residence. Thus the 42 villages named after the Kér tribe are scattered around in Hungary.
Surname or Lastname
English
English : unexplained. Probably of Anglo-Norman French origin; it is said to be from a place called Malbanc.Peter Malbone, born in 1633, married Sarah Godfrey in Norfolk Co., VA. The name Mallabone has been in Warwickshire, England, for over 400 years.
Surname or Lastname
English
English : of uncertain origin; possibly from a reduced form of the personal name Dominick.Chinese : from the name of Meng Mingshi, a senior minister of the state of Qin in the Spring and Autumn period (722–481 bc). His descendants adopted the first character of his given name, which means ‘bright’, as their surname.
Boy/Male
American, Australian, Basque, Chinese, Finnish, French, German, Latin, Spanish, Swedish
Healthy; Strong; Valiant; The Name of More than 50 Saints and Three Roman Emperors
Surname or Lastname
English and French
English and French : nickname for a tall person, from Old English lang, long, Old French long ‘long’, ‘tall’ (equivalent to Latin longus).Irish (Ulster (Armagh) and Munster) : reduced Anglicized form of Gaelic Ó Longáin (see Langan).Chinese : from the name of an official treasurer called Long, who lived during the reign of the model emperor Shun (2257–2205 bc). his descendants adopted this name as their surname. Additionally, a branch of the Liu clan (see Lau 1), descendants of Liu Lei, who supposedly had the ability to handle dragons, was granted the name Yu-Long (meaning roughly ‘resistor of dragons’) by the Xia emperor Kong Jia (1879–1849 bc). Some descendants later simplified Yu-Long to Long and adopted it as their surname.Chinese : there are two sources for this name. One was a place in the state of Lu in Shandong province during the Spring and Autumn period (722–481 bc). The other source is the Xiongnu nationality, a non-Han Chinese people.Chinese : variant of Lang.Cambodian : unexplained.
Surname or Lastname
English
English : patronymic from Low 3 and 4.English : topographic name rom the plural of Middle English lowe ‘mound’, ‘hill’ (see Low 1).
Male
German
 German form of Latin Valentinus, VALENTIN means "healthy, strong." Compare with other forms of Valentin.
Surname or Lastname
English
English : variant of Lyon 3.Irish : variant of Lyon 4.
Surname or Lastname
English
English : variant of Long 1.German and French (Alsace–Lorraine) : from Middle High German lunge ‘lung’, presumably applied as a nickname.Chinese : variant of Long 3.Chinese : variant of Long 4.
GALECTIN 4
GALECTIN 4
Surname or Lastname
English
English : habitational name from any of several places in Cumbria named Brownrigg, from Old English brūn ‘brown’ + hrycg ‘ridge’.
Boy/Male
Hindu
Lamp, Kindle, Radiant
Girl/Female
Hindu
Lord of gods
Boy/Male
Muslim/Islamic
Horse like animal that carried the Prophet (PBUH) during mehraj and will carry those that are selected on resurrection day
Boy/Male
Hindu
Surname or Lastname
English
English : variant spelling of Prior.Americanized form of some like-sounding Jewish surname.
Girl/Female
Assamese, Bengali, Hindu, Indian, Marathi
Handsome; Beautiful Radha
Girl/Female
Arabic, Australian, French
Powerful
Boy/Male
Arabic, Muslim
Servant of the Only One (Allah)
Girl/Female
Tamil
GALECTIN 4
GALECTIN 4
GALECTIN 4
GALECTIN 4
GALECTIN 4
n.
An old game of ball played with a trap. See 4th Trap, 4.
a.
Of or pertaining to the galaxy or Milky Way.
a.
Composed of parts united according to a law of twinning. See Twin, n., 4.
n.
A universal proposition. See Universal, a., 4.
n.
A South American animal of the family Mustelidae (Galictis vittata). It is about two feet long, exclusive of the tail. Its under parts are black. Also called South American glutton.
n.
A playful, humorous movement, commonly in 3-4 measure, which often takes the place of the old minuet and trio in a sonata or a symphony.
v. i.
To prey. See 4th Tire.
n.
The ornament of woodwork upon the gable of a house, used extensively in the 15th century. It was generally suspended from the edge of the projecting roof (see Verge, n., 4), and in position parallel to the gable wall. Called also bargeboard.
n.
Same as Wale, n., 4.
v. t.
To embellish; to change fancifully; to present under new aspects, as of form, key, measure, etc. See Variation, 4.
a.
Not tended; not dressed. See 4th Tent.
n.
A Scotch round dance in 2-4 time, similar to the polka, only slower; also, the music for such a dance; -- not to be confounded with the Ecossaise.
n.
An amorphous, gummy carbohydrate resembling gelose, found in the seeds of leguminous plants, and yielding on decomposition several sugars, including galactose.
v. t.
To provide with a trap; as, to trap a drain; to trap a sewer pipe. See 4th Trap, 5.
n.
A rare metallic element of the boron group, whose existence was predicted under the provisional name ekaboron by means of the periodic law, and subsequently discovered by spectrum analysis in certain rare Scandinavian minerals (euxenite and gadolinite). It has not yet been isolated. Symbol Sc. Atomic weight 44.
a.
Of or pertaining to milk; got from milk; as, galactic acid.
n.
See Umber, 4.
n.
A white waxy substance found in the sap of the South American cow tree (Galactodendron).
a.
Composed of parts united according to some definite law of twinning. See Twin, n., 4.
n.
An amorphous, gelatinous substance containing nitrogen, found in milk and other animal fluids. It resembles peptone, and is variously regarded as a coagulating or emulsifying agent.