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Chemical compound of RNA
guanine (G). In RNA, uracil binds to adenine via two hydrogen bonds. In DNA, the uracil nucleobase is replaced by thymine (T). Uracil is a demethylated form
Uracil
Chemical compound in nucleic acids
nucleotide bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring
Cytosine
Enzyme that repairs DNA damage
Uracil-DNA glycosylase (also known as UNG or UDG) is an enzyme. Its most important function is to prevent mutagenesis by eliminating uracil from DNA molecules
Uracil-DNA_glycosylase
Chemical compound of DNA
thymine may be derived by methylation of uracil at the 5th carbon. In RNA, thymine is replaced with uracil in most cases. In DNA, thymine (T) binds to
Thymine
Aromatic compound (C4H4N2)
nucleobases are pyrimidine derivatives: cytosine (C), thymine (T), and uracil (U). The pyrimidine ring system has wide occurrence in nature as substituted
Pyrimidine
Nitrogen-containing biological compounds that form nucleosides
Five nucleobases—adenine (A), cytosine (C), guanine (G), thymine (T), and uracil (U)—are called primary or canonical. They function as the fundamental units
Nucleotide_base
Chemical compound
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism
Uridine_diphosphate_glucose
Chemotherapy drug used in the treatment of cancer
Tegafur/uracil (abbreviation: UFT) is a chemotherapy drug combination used in the treatment of cancer, primarily bowel cancer. UFT is an oral formulation
Tegafur/uracil
Chemotherapy medication
Abraham Cantarow and Karl Paschkis found liver tumors absorbed radioactive uracil more readily than did normal liver cells. Charles Heidelberger, who had
Fluorouracil
Class of enzymes
Uracil dehydrogenase (EC 1.1.99.19, uracil oxidase) is an enzyme with systematic name uracil:(acceptor) oxidoreductase. This enzyme catalyses the following
Uracil_dehydrogenase
Chemical compound of DNA and RNA
nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside
Guanine
Cellular mechanism in B cells
cytosine to uracil in DNA by the enzyme activation-induced cytidine deaminase, or AID. A cytosine:guanine pair is thus directly mutated to a uracil:guanine
Somatic_hypermutation
Class of enzymes
Uracil/thymine dehydrogenase (EC 1.17.99.4, uracil oxidase, uracil-thymine oxidase, uracil dehydrogenase) is an enzyme with systematic name uracil:acceptor
Uracil/thymine_dehydrogenase
Class of enzymes
Uracil phosphoribosyltransferase is an enzyme which interconverts uridine monophosphate with uracil and phosphoribosyl pyrophosphate. In the forward direction
Uracil phosphoribosyltransferase
Uracil_phosphoribosyltransferase
Removal of an amino group from a molecule
urine. Spontaneous deamination is the hydrolysis reaction of cytosine into uracil, releasing ammonia in the process. This can occur in vitro through the use
Deamination
pseudouridine synthase 3) is an enzyme with systematic name tRNA-uridine38/39 uracil mutase. This enzyme catalyses the following chemical reaction tRNA uridine38/39
TRNA pseudouridine38/39 synthase
TRNA_pseudouridine38/39_synthase
Class of enzymes
catalyzes the chemical reaction O3-acetyl-L-serine + uracil ⇌ {\displaystyle \rightleftharpoons } 3-(uracil-1-yl)-L-alanine + acetate Thus, the two substrates
Uracilylalanine_synthase
RNA that is read by the ribosome to produce a protein
contains thymine (T), RNA contains uracil (U). During the process of transcription, the enzyme RNA polymerase incorporates uracil opposite adenine bases located
Messenger_RNA
DNA repair process
difficult to recognize, but can be repaired by mismatch-specific glycosylases) Uracil inappropriately incorporated in DNA or formed by deamination of cytosine
Base_excision_repair
Chemical compound
biomolecules. Recent work has also used EDC to assess the structure state of uracil nucleobases in RNA. EDC is commercially available. It may be prepared by
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
Family of large biological molecules
to convey genetic information (using the nitrogenous bases of guanine, uracil, adenine, and cytosine, denoted by the letters G, U, A, and C) that directs
RNA
Class of enzymes
uracil reductase (EC 1.1.1.193) is an enzyme that catalyzes the chemical reaction 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP+
5-amino-6-(5-phosphoribosylamino)uracil reductase
5-amino-6-(5-phosphoribosylamino)uracil_reductase
Species of lactic acid bacteria
tested to determine a starting point for the media. Tween 80, uracil and combinations of uracil, adenine, and xanthine are not required for growth. Subsp
Leuconostoc_mesenteroides
In enzymology, a tRNA (uracil-5-)-methyltransferase (EC 2.1.1.35) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + tRNA containing
TRNA (uracil-5-)-methyltransferase
TRNA_(uracil-5-)-methyltransferase
Enzyme
polymerases from archaea is sensitive to Uracil residues in DNA and is strongly inhibited by dUTP or uracil residues in DNA. The inhibition of this class
Pfu_DNA_polymerase
Class of HIV/AIDS drugs
interact at the C-terminal domain of the HIV-1 capsid, similar to Ebselen. Uracil based scaffolds such as bispyrimidine dione and tetrapyrimidine dione derivatives
HIV_capsid_inhibition
Class of large biomolecules essential to all known life
are: adenine, cytosine, guanine, thymine, and uracil. Thymine occurs only in DNA[dubious – discuss] and uracil only in RNA. Using amino acids and protein
Nucleic_acid
Biochemical process
is deaminated and becomes a uracil base. This causes a U:G mispair which is detected by Uracil DNA glycosylase. The uracil base is flipped out into the
DNA_base_flipping
Chemical compound
Uramustine (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as
Uramustine
Lab procedure detecting 5-methylcytosines in DNA
activity. Treatment of DNA with bisulfite converts cytosine residues to uracil, but leaves 5-methylcytosine residues unaffected. Therefore, DNA that has
Bisulfite_sequencing
Method for analyzing DNA methylation using enzymes
converted into uracil (U) through enzymatic conversion before sequencing and read as thymine (T). This enzymatic conversion of cytosine to uracil is achieved
Enzymatic_methyl-seq
synthases 2) is an enzyme with systematic name mitochondrial tRNA-uridine27/28 uracil mutase. This enzyme catalyses the following chemical reaction mitochondrial
Mitochondrial tRNA pseudouridine27/28 synthase
Mitochondrial_tRNA_pseudouridine27/28_synthase
Biological molecules constituting nucleic acids
DNA are guanine, adenine, cytosine, and thymine (G, A, C, and T); in RNA, uracil (U) is used in place of thymine. Nucleotides also play a central role in
Nucleotide
Class of enzymes
enzyme uracil-5-carboxylate decarboxylase (EC 4.1.1.66) catalyzes the chemical reaction uracil 5-carboxylate ⇌ {\displaystyle \rightleftharpoons } uracil +
Uracil-5-carboxylate decarboxylase
Uracil-5-carboxylate_decarboxylase
Class of enzymes
the chemical reaction uracil + NADPH H+ H+ dihydrouracil + NADP+ In the catabolism of uracil, the enzyme converts uracil to dihydrouracil using
Dihydropyrimidine dehydrogenase (NADP+)
Dihydropyrimidine_dehydrogenase_(NADP+)
Two nucleobases bound by hydrogen bonds
"Watson–Crick–Franklin") base pairs (guanine–cytosine and adenine–thymine/uracil) allow the DNA helix to maintain a regular helical structure that is subtly
Base_pair
Chemical compound
Uracil glycol is a major oxidation product of cytosine in DNA. It can be readily bypassed by E. coli DNA polymerase I (unlike thymine glycol) and be a
Uracil_glycol
Mechanism of termination of RNA transcription
is followed immediately downstream by multiple uracil nucleotides. The hydrogen bonds between uracil (rU) and adenine (dA) are very weak. A protein bound
Intrinsic_termination
Chemical compound in DNA and RNA
shape of adenine is complementary and pairs to either thymine in DNA or uracil in RNA. In cells, adenine is rare as an independent molecule. It is almost
Adenine
Enzymes involved in base excision repair
family, Uracil-DNA glycosylase (UDG) is an enzyme that reverts mutations in DNA. The most common mutation is the deamination of cytosine to uracil. UDG repairs
DNA_glycosylase
Class of enzymes
Double-stranded uracil-DNA glycosylase (EC 3.2.2.28, Mug, double-strand uracil-DNA glycosylase, Dug, dsUDG, double-stranded DNA specific UDG, dsDNA specific
Double-stranded uracil-DNA glycosylase
Double-stranded_uracil-DNA_glycosylase
Chemical compound
compound having a pyrimidine skeleton. It is a derivative of the nucleobase uracil with a sulfur instead of oxygen in position 4. It is found naturally in
4-Thiouracil
Succession of nucleotides in a nucleic acid
for RNA, except with U (uracil) replacing T (thymine). Apart from adenine (A), cytosine (C), guanine (G), thymine (T) and uracil (U), DNA and RNA also contain
Nucleic_acid_sequence
Study of chemical processes of living organisms
thymine and uracil, thymine binds only with adenine, and cytosine and guanine can bind only with one another. Adenine, thymine, and uracil contain two
Biochemistry
Topics referred to by the same term
delta baryon with composition (uuu) -- triple up quarks UUU, or uracil uracil uracil, the RNA codon for phenylalanine Uranium One (TSX: UUU, JSE: UUU)
UUU
DNA or mRNA sequence representing the end of transcription or translation
that has high amounts of guanine and cytosine, as well as a region high in uracil nucleobases. Factor-dependent terminators require proteins for proper termination
Termination_signal
hydrolytic deamination to create uracil sulfonate. Under alkaline conditions, uracil sulfonate desulfonates to generate uracil. This enables methylation detection
Whole genome bisulfite sequencing
Whole_genome_bisulfite_sequencing
Biological process
exclusively in DNA and uracil exclusively in RNA may have evolved as an error-control mechanism, to facilitate the removal of uracils generated by the spontaneous
DNA_methylation
Molecule that carries genetic information
corresponding bases except in the case of thymine (T), for which RNA substitutes uracil (U). Under the genetic code, these RNA strands specify the sequence of amino
DNA
RNA base pair that does not follow Watson–Crick base pair rules
base pair rules. The four main wobble base pairs are guanine–uracil (G–U), hypoxanthine–uracil (I–U), hypoxanthine–adenine (I–A), and hypoxanthine–cytosine
Wobble_base_pair
Chemical compound synthesized in the body via a mitochondrial enzyme
Thomas B (1986). "The structures of tetraaqua(uracil-6-carboxylate)zinc(II) monohydrate (A) and tetraaqua(uracil-6-carboxylato)nickel(II) monohydrate (B)"
Orotic_acid
base, is observed within the uracil DNA glycosylase superfamily. Currently, there are 6 families within the DNA Uracil Glycosylase superfamily, each
DNA-deoxyinosine_glycosylase
Class of enzymes
RluC) is an enzyme with the systematic name 23S rRNA-uridine955/2504/2580 uracil mutase. This enzyme catalyses the following chemical reaction 23S rRNA
23S rRNA pseudouridine955/2504/2580 synthase
23S_rRNA_pseudouridine955/2504/2580_synthase
pseudouridylate synthase (EC 4.2.1.70) catalyzes the chemical reaction uracil + D-ribose 5-phosphate ⇌ {\displaystyle \rightleftharpoons } pseudouridine
Pseudouridylate_synthase
Apollo asteroid
December 2020. The samples showed the presence of organic compounds, such as uracil (one of the four components in RNA) and vitamin B3. Ryugu was discovered
162173_Ryugu
In enzymology, a tRNA-pseudouridine synthase I (EC 5.4.99.12) is an enzyme that catalyzes the chemical reaction tRNA uridine ⇌ {\displaystyle \rightleftharpoons
TRNA-pseudouridine_synthase_I
Enzyme
pseudouridine synthase RluA) is an enzyme with systematic name 23S rRNA-uridine746 uracil mutase. This enzyme catalyses the following chemical reaction 23S rRNA uridine746
23S rRNA pseudouridine746 synthase
23S_rRNA_pseudouridine746_synthase
Protein-coding gene in the species Homo sapiens
monofunctional uracil DNA glycosylase is an enzyme that in humans is encoded by the SMUG1 gene. SMUG1 is a glycosylase that removes uracil from single-
SMUG1
Chemical compound
2-Thiouracil is a chemical derivative of uracil in which the oxygen atom in the 2-position of the ring is substituted by sulfur. It is classified as a
2-Thiouracil
Laboratory technique for DNA methylation profiling
two-step enzymatic conversion of methylated cytosines, 5mC and 5hmC, to uracil which is read as a thymine after sequencing. Due to direct conversion of
TET-assisted pyridine borane sequencing
TET-assisted_pyridine_borane_sequencing
In enzymology, a methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (EC 2.1.1.74) is an enzyme that catalyzes the chemical reaction 5
Methylenetetrahydrofolate—tRNA-(uracil-5-)-methyltransferase
Methylenetetrahydrofolate—tRNA-(uracil-5-)-methyltransferase
Chemicals that inhibit the use of a metabolite
which are found in both DNA and RNA, thymine (T) which is DNA specific, and uracil (U) which is RNA specific. The five nucleotides are separated into two groups
Pyrimidine_analogue
Cellular mechanism
base-excision repair enzyme uracil-DNA glycosylase excising a hydrolytically-produced uracil residue from DNA. The uracil residue is shown in yellow.
DNA_repair
Chemical compound
incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to cardiotoxicity
Idoxuridine
Chemical compound
treatment of cancers. It is a component of the combination drug tegafur/uracil. When metabolised, it becomes 5-FU. It was patented in 1967 and approved
Tegafur
Inability to synthesize an organic compound required for growth
resultant strain is a uracil auxotroph). Such a strain is unable to synthesize uracil and will only be able to grow if uracil can be taken up from the
Auxotrophy
Chemical compound
Greek letter psi- Ψ) is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic
Pseudouridine
Assembly of proteins inside biological cells
four bases: guanine, cytosine, adenine and uracil. In RNA molecules, the DNA base thymine is replaced by uracil which is able to base pair with adenine.
Protein_biosynthesis
ensuring that the organism's DNA contains the nucleobase thymine instead of uracil. DUT, the human version of this gene dnaA dnaB dnaC dnaE dnaG dnaH dnaI
DnaS
Technique in molecular biology
resulting in a high level of dUTP in the cell. The uracil deglycosidase deficiency prevents the removal of uracil from newly synthesized DNA. As the double-mutant
Site-directed_mutagenesis
Topics referred to by the same term
UDGB may refer to: Double-stranded uracil-DNA glycosylase, an enzyme Uracil-DNA glycosylase, an enzyme This disambiguation page lists articles associated
UDGB
Property of nucleic acid strands with respect to their translatability into protein
(provided that any thymine bases in the DNA sequence are replaced with uracil bases in the RNA sequence). The other strand of the double-stranded DNA
Sense_(molecular_biology)
Chemical compound
metabolic intermediate in a strain of Escherichia coli that can grow on uracil as its sole nitrogen source. 3-Oxopropanoic acid also occurs in atmospheric
3-Oxopropanoic_acid
(poly-(U)-specific) (EC 3.1.26.9, ribonuclease (uracil-specific), uracil-specific endoribonuclease, uracil-specific RNase) is an enzyme. This enzyme catalyses
Ribonuclease (poly-(U)-specific)
Ribonuclease_(poly-(U)-specific)
Scientific hypotheses on the origin and evolution of DNA
all five primary nucleobases for DNA and RNA (including the pyrimidines uracil, cytosine, and thymine) are present in carbonaceous meteorites. Complex
Origin_of_DNA
name uracil,FMNH2:oxygen oxidoreductase (uracil hydroxylating, ring-opening). This enzyme catalyses the following chemical reaction (1) uracil + FMNH2
Pyrimidine_oxygenase
Virus that causes COVID-19
like other coronaviruses. The genome has the highest composition of U (uracil) (32.2%), followed by A (adenine) (29.9%), and a similar composition of
SARS-CoV-2
Class of enzymes
21, RluF, YjbC) is an enzyme with systematic name 23S rRNA-uridine2604 uracil mutase. This enzyme catalyses the following chemical reaction 23S rRNA uridine2604
23S rRNA pseudouridine2604 synthase
23S_rRNA_pseudouridine2604_synthase
Class of enzymes
synthase (EC 4.3.1.32, FO synthase) and 5-amino-6-(D-ribitylamino)uracil—L-tyrosine 4-hydroxyphenyl transferase (EC 2.5.1.147) are two enzymes always
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase
7,8-didemethyl-8-hydroxy-5-deazariboflavin_synthase
Norwegian molecular biologist and barophysiologist
barophysiology Institutions Norwegian University of Science and Technology Thesis Heterogeneity in the incorporation and excision of uracil in DNA (1993)
Ingrid_Eftedal
Species of alga
selection marker for transformation in C. merolae involves a uracil auxotroph (requiring exogenous uracil). The mutant was developed by growing C. merolae in the
Cyanidioschyzon
Percentage of guanine and cytosine in DNA or RNA molecules
total bases, also including adenine and thymine in DNA and adenine and uracil in RNA. GC-content may be given for a certain fragment of DNA or RNA or
GC-content
common in ribosomal RNA: GNRA, UNCG and CUUG, in which the N could be either uracil, adenine, cytosine, or guanine, and the R is either guanine or adenine.
Tetraloop
Protein-coding gene in the species Homo sapiens
dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting
DUT_(gene)
Highly conserved RNA element
riboswitch, thereby providing a continuous stacking alignment. Further, the uracil-like edge of the ring system forms specific Watson–Crick-like hydrogen bonds
FMN_riboswitch
Hypothetical stage in the early evolutionary history of life on Earth
DNA—adenine, guanine, cytosine and uracil, instead of adenine, guanine, cytosine and thymine. Chemically, uracil is similar to thymine, differing only
RNA_world
Experimental process
exposed uracil, and to a smaller extent guanine nucleobases, upon nucleophilic attack by a deprotonated nitrogen. They react primarily with N3 of uracil and
Nucleic acid structure determination
Nucleic_acid_structure_determination
5.4.99.26, TruC, YqcB) is an enzyme with systematic name tRNA-uridine65 uracil mutase. This enzyme catalyses the following chemical reaction tRNA uridine65
TRNA_pseudouridine65_synthase
Topics referred to by the same term
(Vanuatu) Fungwa language, Nigeria Ura (dance), of the Cook Islands Ura, or uracil, a nucleobase of RNA Ura (Russian: Ура!), a Russian battle cry Ura (surname)
Ura
Chemical compound or ion
cytosines in DNA. In this technique, sodium bisulfite deaminates cytosine into uracil, but does not affect 5-methylcytosine, a methylated form of cytosine with
Bisulfite
Protein-coding gene in the species Homo sapiens
Uracil nucleotide/cysteinyl leukotriene receptor is a G protein-coupled receptor that in humans is encoded by the GPR17 gene located on chromosome 2 at
GPR17
Chemical compound
Ainuovirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) being developed by Kainos Medicine for the treatment of HIV infections. Ainuovirine
Ainuovirine
Lock-and-key pairing between two structures
nucleobases: adenine, thymine (uracil in RNA), guanine and cytosine. Adenine and guanine are purines, while thymine, cytosine and uracil are pyrimidines. Purines
Complementarity (molecular biology)
Complementarity_(molecular_biology)
Central nervous system stimulant
Kowal MG, Narayan S (2003). "A Novel Method of Caffeine Synthesis from Uracil". Synthetic Communications. 33 (19): 3291–3297. doi:10.1081/SCC-120023986
Caffeine
Index of chemical compounds with the same molecular formula
uncommon amino acid Dihydrouracil, an intermediate in the catabolism of uracil 2,5-Diketopiperazine Ethyl diazoacetate, a reagent used in organic chemistry
C4H6N2O2
post-mortem is the hydrolytic deamination of cytosines, converting them in uracils, which are then read as thymines. Due to this reaction, ancient DNA contains
Ancient_pathogen_genomics
File format for DNA or protein sequences
Code Meaning Mnemonic A A Adenine C C Cytosine G G Guanine T T Thymine U U Uracil (i) i inosine (non-standard) R A or G (I) puRine Y C, T or U pYrimidines
FASTA_format
Chemical compound
nitrogenous base uracil found in RNA. It is one member of a family of willardiine compounds, which share uracil or a substituted uracil as an amino acid
5-Fluorowillardiine
DNA or RNA sequence that matches its complement when read backwards
nucleotides always pair in the same way (adenine (A) with thymine (T) in DNA or uracil (U) in RNA; cytosine (C) with guanine (G)), a (single-stranded) nucleotide
Palindromic_sequence
Anti-diabetic drug
Alogliptin, sold under the brand names Nesina and Vipidia, is an oral anti-diabetic drug in the DPP-4 inhibitor (gliptin) class. Like other members of
Alogliptin
URACIL
URACIL
URACIL
URACIL
Female
Polish
Feminine form of Polish Justyn, JUSTYNA means "fair, just."
Male
English
Variant spelling of English Adalia, ADALIAH means "I shall be drawn up of God."Â
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Sindhi, Telugu
Loving; Sweet
Surname or Lastname
English
English : probably a respelling of Irish Taaffe. In England this name now occurs mainly in South Yorkshire.
Male
German
Germanic name derived from the word hraban, HRABAN means "raven."
Girl/Female
Indian
Happy, Lucky
Boy/Male
English German
Famous ruler.
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Sanskrit, Tamil
Pure; Flower; Daughter of God; Holy
Girl/Female
Hindu
Girl/Female
Indian
Affection, Happy
URACIL
URACIL
URACIL
URACIL
URACIL