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Mammalian protein found in Homo sapiens
The thyrotropin receptor (or TSH receptor) is a receptor (and associated protein) that responds to thyroid-stimulating hormone (also known as "thyrotropin")
Thyrotropin_receptor
Autoimmune endocrine disease
genes Genes believed to be involved include those for thyroglobulin, thyrotropin receptor, protein tyrosine phosphatase nonreceptor type 22 (PTPN22), and cytotoxic
Graves'_disease
Protein-coding gene in the species Homo sapiens
Thyrotropin-releasing hormone receptor (TRHR) is a G protein-coupled receptor which binds thyrotropin-releasing hormone. The TRHR is found on the cell
Thyrotropin-releasing hormone receptor
Thyrotropin-releasing_hormone_receptor
Family of glycoprotein hormones in vertebrata
Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland
Thyroid-stimulating_hormone
Hormone
Thyrotropin-releasing hormone (TRH) is a hypophysiotropic hormone produced by neurons in the hypothalamus that stimulates the release of thyroid-stimulating
Thyrotropin-releasing_hormone
Excessive production of thyroid hormone
thyroid scan, and measurement of antithyroid autoantibodies (thyroidal thyrotropin receptor antibodies are positive in Graves' disease) may help determine the
Hyperthyroidism
Cell surface receptors
peptide receptor is a type of receptor which binds one or more signaling peptides or signaling proteins. An example is the tropomyosin receptor kinase
Signaling_peptide_receptor
Antibodies targeted against the thyroid
anti-thyroid peroxidase antibodies (anti-TPO antibodies, TPOAb), thyrotropin receptor antibodies (TRAb) and thyroglobulin antibodies (TgAb). TRAb's are
Antithyroid_autoantibodies
Autoimmune disease
pathogenesis of autoimmune thyroid diseases and production of anti-thyrotropin receptor antibody". Clinical and Experimental Immunology. 156 (2): 199–204
Hashimoto's_thyroiditis
Pharmaceutical compound
the neonatal fragment crystallizable receptor, which leads to a reduction in antibodies of the thyrotropin receptor. It is being developed to treat myasthenia
Batoclimab
Medical condition
tests for antibodies (anti-thyroglobulin, anti-microsomal and anti-thyrotropin receptor) and abnormalities in thyroid hormones level (T3, T4, and TSH) help
Graves'_ophthalmopathy
Class of cell surface receptors coupled to G-protein-associated intracellular signaling
protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G
G_protein-coupled_receptor
Part of the neuroendocrine system
pituitary thyroid hormone receptors. Standard procedures cover the determination of serum levels of the following hormones: TSH (thyrotropin, thyroid stimulating
Hypothalamic–pituitary–thyroid axis
Hypothalamic–pituitary–thyroid_axis
Transmembrane receptor found in humans
to Lys-211) and 9 amino acids (Gly-222 to Leu-230) in the human thyrotropin receptor are involved in ligand binding". The Journal of Biological Chemistry
Luteinizing hormone/choriogonadotropin receptor
Luteinizing_hormone/choriogonadotropin_receptor
Family of proteins
U receptor 2 (NMUR2) Neurotensin receptor InterPro: IPR003984 Neurotensin receptor 1 (NTSR1, NTR1) Neurotensin receptor 2 (NTSR2, NTR2) Thyrotropin-releasing
Rhodopsin-like_receptors
They regulate diverse physiological processes by binding to specific receptors. Human hormones are commonly grouped into four major structural classes:
List_of_human_hormones
Group of proteins
Luteinizing hormone Progesterone receptors Retinoid receptors Somatostatin receptors Thyroid hormone receptors Thyrotropin receptors Aranda, A.; Pascual, A. (2001-07-01)
Hormone_receptor
Class of G protein-coupled receptors
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)
Adrenergic_receptor
Antibody directed against an autogenic protein
particular disease is different for different diseases. Anti-glutamate receptor antibodies Reference ranges for blood tests#Autoantibodies Paraneoplastic
Autoantibody
Class of opioid receptors found in humans
The μ-opioid receptors (using the Greek letter mu, abbreviated MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin
Mu-opioid_receptor
Posatirelin Protirelin Rovatirelin Taltirelin TRH (TRF) Agonists: Thyrotropin alfa TSH (thyrotropin) See here instead. Agonists: Peptide: Bay 55-9837 LBT-3393
List of signaling peptide/protein receptor modulators
List_of_signaling_peptide/protein_receptor_modulators
Mammalian protein found in humans
Cannabinoid receptor 1 (CB1), is a G protein-coupled cannabinoid receptor that in humans is encoded by the CNR1 gene. It was discovered by determination
Cannabinoid_receptor_1
Mammalian protein found in Homo sapiens
hormone receptors PTH1R and PTH2R Prostaglandin receptor types D2 and I2 Secretin receptor Thyrotropin receptor Trace amine-associated receptor 1 Vasopressin
Gs_alpha_subunit
thyroid stimulating hormone TSH thyroid stimulating hormone TSHR-Ab thyrotropin-receptor antibody TSI thyroid Stimulating Immunoglobulin T.S.T.H. too sick
List of medical abbreviations: T
List_of_medical_abbreviations:_T
Neuroendocrine cells in the thyroid
R, Martín-Lacave I (August 2009). "Functional expression of the thyrotropin receptor in C cells: new insights into their involvement in the
Parafollicular_cell
Valente, William (July 19, 1982). "Monoclonal antibodies to the thyrotropin receptor: Stimulating and blocking antibodies derived from the lymphocytes
Blocking_antibody
Receptors that respond to gamma-aminobutyric acid
of GABA receptors: GABAA and GABAB. GABAA receptors are ligand-gated ion channels (also known as ionotropic receptors); whereas GABAB receptors are G protein-coupled
GABA_receptor
Class of G protein-coupled receptors
Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate
Dopamine_receptor
Protein family and hormone
inhibitory hormone) to act on the D2 receptors of lactotrophs, causing inhibition of prolactin secretion. Thyrotropin-releasing hormone has a stimulatory
Prolactin
Main receptor for most antipsychotic drugs
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul Greengard's lab had suggested
Dopamine_receptor_D2
Acetylcholine receptors named for their selective binding of muscarine
Muscarinic acetylcholine receptors (mAChRs) are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain
Muscarinic acetylcholine receptor
Muscarinic_acetylcholine_receptor
Mammalian protein found in humans
The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline)
Beta-2_adrenergic_receptor
Group of receptors to cannabinoid compounds
Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system of vertebrates– a class of cell membrane receptors in the G protein-coupled
Cannabinoid_receptor
Medical condition
hyperplasia in patients with Graves' disease. Identification of thyrotropin receptors in human thymus". Journal of Clinical Investigation. 98 (10): 2228–34
Thymus_hyperplasia
Subtype of serotonin receptor
5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and functions as a G protein-coupled receptor (GPCR)
5-HT2A_receptor
Protein-coding gene in the species Homo sapiens
Van Sande J, Spicher K, Schultz G, Dumont JE (1994). "The human thyrotropin receptor activates G-proteins Gs and Gq/11". J. Biol. Chem. 269 (19): 13733–5
GNAQ
G protein-coupled receptor
The alpha-1 (α1) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G protein. It consists
Alpha-1_adrenergic_receptor
Protein family
The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists
Alpha-2_adrenergic_receptor
Hormone-producing cell in the thyroid gland
follicular lumen. The basolateral membrane of follicular cells contains thyrotropin receptors which bind to thyroid-stimulating hormone (TSH) found circulating
Thyroid_follicular_cell
Type of cellular receptor that facilitates taste
A taste receptor is a type of cellular receptor that facilitates the sensation of taste. When food or other substances enter the mouth, molecules interact
Taste_receptor
Protein-coding gene in the species Homo sapiens
peripheral nervous system. These hormones include dopamine, norepinephrine, thyrotropin-releasing hormone, and corticotropin-releasing hormone. Many of these
Somatostatin_receptor_2
Class of four receptor proteins to the molecule adenosine
The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as the endogenous ligand. There are four
Adenosine_receptor
Protein-coding gene in the species Homo sapiens, named for ketazocine
The κ-opioid receptor or kappa opioid receptor, abbreviated KOR or KOP for its ligand ketazocine, is a G protein-coupled receptor that is encoded by the
Κ-opioid_receptor
Receptor activated by peptide hormone GLP-1
The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It
Glucagon-like peptide-1 receptor
Glucagon-like_peptide-1_receptor
Cell surface protein binding somatostatin and triggering intracellular changes
Somatostatin receptors are receptors for somatostatin, a small neuropeptide associated with inhibitory signaling in wide range of tissues, including the
Somatostatin_receptor
Neuron membrane protein
Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base
Glutamate_receptor
Protein-coding gene in the species Homo sapiens
receptor (β1 adrenoceptor), also known as ADRB1, can refer to either the protein-encoding gene (gene ADRB1) or one of the four adrenergic receptors.
Beta-1_adrenergic_receptor
Protein-coding gene in humans
"Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled
LGR5
Protein controlling mammalian coloration
melanocortin 1 receptor (MC1R), also known as melanocyte-stimulating hormone receptor (MSHR), melanin-activating peptide receptor, or melanotropin receptor, is a
Melanocortin_1_receptor
Protein-coding gene in the species Homo sapiens
The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by
Muscarinic acetylcholine receptor M1
Muscarinic_acetylcholine_receptor_M1
Protein-coding gene in the species Homo sapiens
Thyroid hormone receptor beta (TR-beta) also known as nuclear receptor subfamily 1, group A, member 2 (NR1A2), is a nuclear receptor protein that in humans
Thyroid_hormone_receptor_beta
Integral membrane protein
An acetylcholine receptor (abbreviated AChR) or a cholinergic receptor is an integral membrane protein that responds to the binding of acetylcholine,
Acetylcholine_receptor
Protein-coding gene in the species Homo sapiens
S2CID 39457788. Lahuna O, Quellari M, Achard C, et al. (2005). "Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway". EMBO
SCRIB
Type of protein
A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter. Chemicals on the outside
Neurotransmitter_receptor
Protein-coding gene in the species Homo sapiens
Van Sande J, Dumont JE, et al. (Jan 1996). "The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein
GNA13
TRH analog with use for CNS disorders
Montirelin binds to TRH receptors in the brain, stimulating the release of thyrotropin (TSH) and prolactin. It exhibits sustained receptor occupancy and a counter-clockwise
Montirelin
Substance promoting lactation
due to their ability to block the D2 receptor Certain hormones such as oxytocin, growth hormone (GH), and thyrotropin-releasing hormone (TRH). Progestogens
Galactagogue
Group of biological receptors
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins
Opioid_receptor
Protein-coding gene in the species Homo sapiens
1996). "Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor". Journal of Biological Chemistry. 271
GRK5
Medical condition
hypothalamic destruction Defective thyrotropin-releasing hormone molecules Defective thyrotropin-releasing hormone-thyrotropin receptors Lymphocytic thyroiditis
Hypothyroidism_in_dogs
Human protein and coding gene
(September 1996). "GRK2 and beta-arrestin 1 as negative regulators of thyrotropin receptor-stimulated response". Molecular Endocrinology. 10 (9): 1138–1146
Arrestin_beta_1
Chemoreceptors expressed in cell membranes of olfactory receptor neurons
Olfactory receptors (ORs), also known as odorant receptors, are chemoreceptors expressed in the cell membranes of olfactory receptor neurons and are responsible
Olfactory_receptor
Class of G protein-coupled receptors
The angiotensin II receptors, (ATR1) and (ATR2), are a class of G protein-coupled receptors with angiotensin II as their ligands. They are important in
Angiotensin_II_receptor
Protein-coding gene in the species Homo sapiens
The dopamine receptor D4 is a dopamine D2-like G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5. The structure of DRD4 has
Dopamine_receptor_D4
Histamine receptor
The H1 receptor is a histamine receptor belonging to the family of rhodopsin-like G-protein-coupled receptors. This receptor is activated by the biogenic
Histamine_H1_receptor
Mammalian protein found in Homo sapiens
The cannabinoid receptor 2 (CB2), is a G protein-coupled receptor from the cannabinoid receptor family that in humans is encoded by the CNR2 gene. It
Cannabinoid_receptor_2
Drug class
prolactin releasers besides D2 receptor antagonists include estrogens (e.g., estradiol), progestogens (e.g., progesterone), thyrotropin-releasing hormone and analogues
Prolactin_modulator
thrombin receptor - thrombomodulin - thromboxane receptor - thylakoid - thyroid hormone receptor - thyrotropin - thyrotropin receptor - thyrotropin-releasing
Index of biochemistry articles
Index_of_biochemistry_articles
Protein and coding gene in humans
acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the
Muscarinic acetylcholine receptor M3
Muscarinic_acetylcholine_receptor_M3
Protein-coding gene in humans
Sande J, Dumont JE, Schultz G (Jan 1996). "The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein
GNAI1
Protein-coding gene in the species Homo sapiens
Orexin receptor type 2 (Ox2R or OX2), also known as hypocretin receptor type 2 (HcrtR2), is a protein that in humans is encoded by the HCRTR2 gene. It
Orexin_receptor_type_2
The sphingosine-1-phosphate receptors are a class of G protein-coupled receptors that are targets of the lipid signalling molecule Sphingosine-1-phosphate
Sphingosine-1-phosphate receptor
Sphingosine-1-phosphate_receptor
Protein-coding gene in the species Homo sapiens
protein-coupled receptor 4". Hsu SY, Liang SG, Hsueh AJ (1999). "Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular
LGR4
Protein-coding gene in the species Homo sapiens
receptor (α2A adrenoceptor), also known as ADRA2A, is an α2-adrenergic receptor, and also denotes the human gene encoding it. α2-adrenergic receptors
Alpha-2A_adrenergic_receptor
Serotonin receptor protein distributed in the cerebrum and raphe nucleus
The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter
5-HT1A_receptor
Protein-coding gene in the species Homo sapiens
Allgeier A, Offermanns S, et al. (1996). "The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein
GNAO1
G-protein coupled receptor
GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA). GABAB receptors are found in the central nervous system and
GABAB_receptor
Subtype of Dopamine Receptor
Dopamine receptor D3 (DRD3) is a protein belonging to the dopamine receptor family of G protein-coupled receptors. In humans, it is encoded by the DRD3
Dopamine_receptor_D3
Opioid receptor
The δ-opioid receptor, also known as delta opioid receptor or simply delta receptor, abbreviated DOR or DOP, is an inhibitory 7-transmembrane G-protein
Δ-opioid_receptor
Hormone pathway
("prolactin-inhibiting factor", or "PIF"), estradiol, progesterone, thyrotropin-releasing hormone (TRH), and vasoactive intestinal peptide (VIP). The
Hypothalamic–pituitary–prolactin axis
Hypothalamic–pituitary–prolactin_axis
Mammalian protein found in humans
Metabotropic glutamate receptor 5 is an excitatory Gq-coupled G protein-coupled receptor predominantly expressed on the postsynaptic sites of neurons
Metabotropic glutamate receptor 5
Metabotropic_glutamate_receptor_5
Mammalian protein found in humans
The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor involved in regulating energy homeostasis, appetite, and sexual function. It plays
Melanocortin_4_receptor
Protein-coding gene in the species Homo sapiens
receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor (GLP1 receptor). Glucagon-like peptide-2 (GLP2)
Glucagon-like peptide-2 receptor
Glucagon-like_peptide-2_receptor
Class of transmembrane proteins
5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in
5-HT_receptor
Protein-coding gene in the species Homo sapiens
Vasopressin receptor 2 (V2R), or arginine vasopressin receptor 2 (officially called AVPR2), is a protein that acts as receptor for vasopressin. AVPR2 belongs
Vasopressin_receptor_2
Class of ligand activated receptors localized in surface of plama cell membrane
Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of cells. They act in cell
Cell_surface_receptor
Protein-coding gene in the species Homo sapiens
Vasopressin receptor 1A (V1AR), or arginine vasopressin receptor 1A (officially called AVPR1A) is one of the three major receptor types for vasopressin
Vasopressin_receptor_1A
Protein found in humans
Trace amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene. TAAR1 is a
TAAR1
Protein-coding gene in the species Homo sapiens
The alpha-2B adrenergic receptor (α2B adrenoceptor), is a G-protein coupled receptor. It is a subtype of the adrenergic receptor family. The human gene
Alpha-2B_adrenergic_receptor
Chemical compound
Taltirelin (marketed under the tradename Ceredist) is a thyrotropin-releasing hormone (TRH) analog, which mimics the physiological actions of TRH, but
Taltirelin
Mammalian protein found in Homo sapiens
E, Lefort A, Vassart G, Mattei MG (1991). "Localization of human thyrotropin receptor gene to chromosome region 14q3 by in situ hybridization". Cytogenetics
Sodium/iodide_cotransporter
Mammalian protein found in Homo sapiens
The beta-3 adrenergic receptor (β3-adrenoceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it. Actions
Beta-3_adrenergic_receptor
Protein-coding gene in the species Homo sapiens
peptide receptor 2 (FPR2) is a G-protein coupled receptor (GPCR) located on the surface of many cell types of various animal species. The human receptor protein
Formyl_peptide_receptor_2
When a receptor decreases its response to an agonist at high concentration
primarily mediates receptor localization within the membrane, can also affect endocytosis. It is required for the endocytosis of thyrotropin-releasing hormone
Homologous_desensitization
GHB receptor coding gene in the species Homo sapiens
The γ-hydroxybutyrate (GHB) receptor (GHBR), originally identified as GPR172A, is an excitatory G protein-coupled receptor (GPCR) that binds the neurotransmitter
GHB_receptor
Protein-coding gene in the species Homo sapiens
that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this
Tachykinin_receptor_3
Chemical substance that enables neurotransmission
Voltage- gated Ca++ channel Synaptic vesicle Neurotransmitter transporter Receptor Neurotransmitter Axon terminal Synaptic cleft Dendrite A neurotransmitter
Neurotransmitter
Cytokine receptor
Chemokine receptors are cytokine receptors found on the surface of certain cells that interact with a type of cytokine called a chemokine. There have been
Chemokine_receptor
Receptor protein that binds with somatcrinin
The growth-hormone-releasing hormone receptor (GHRHR) is a G-protein-coupled receptor that binds growth hormone-releasing hormone. The GHRHR activates
Growth-hormone-releasing hormone receptor
Growth-hormone-releasing_hormone_receptor
Mammalian protein found in Homo sapiens
5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene. 5-HT2B is a member
5-HT2B_receptor
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