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Search references for LGR5. Phrases containing LGR5
See searches and references containing LGR5!LGR5
Protein-coding gene in humans
(LGR5) also known as G-protein coupled receptor 49 (GPR49) or G-protein coupled receptor 67 (GPR67) is a protein that in humans is encoded by the LGR5
LGR5
Miniaturized and simplified version of an organ
Institute and University Medical Center Utrecht, Netherlands, showed that single LGR5-expressing intestinal stem cells self-organize to crypt-villus structures
Organoid
Dutch molecular genetics and stem cell researcher
the small and large intestines, LGR5, itself also a target of the Wnt signaling pathway. This led to his finding that LGR5 is a stem cell marker in other
Hans_Clevers
Organ found in mammalian skin
part in healing the epidermis after a wound. Stem cells express the marker LGR5+ in vivo. Other structures associated with the hair follicle include the
Hair_follicle
capacity, it was shown in vivo that transient amplifying cells can revert to Lgr5+ CBC stem cells after damage, presumably by direct contact with Paneth cells
List of intestinal stem cell marker genes
List_of_intestinal_stem_cell_marker_genes
O; Ingelfinger, D; Boutros, M; Cruciat, CM; Niehrs, C (2011). "LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling".
List of intestinal epithelial differentiation genes
List_of_intestinal_epithelial_differentiation_genes
Chemical compound
Lenz DR, McLean D, Langer R, et al. (February 2017). "Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory
CHIR99021
Stem cell biologist
scientific research. Barker N; Huch M; Kujala P; et al. (8 January 2010). "Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric
Meritxell_Huch
Protein-coding gene in the species Homo sapiens
the LGR6 gene. Along with the other G-protein coupled receptors LGR4 and LGR5, LGR6 is a Wnt signaling pathway mediator. LGR6 also acts as an epithelial
LGR6
bispecific antibody that targets cancer stem cells by binding to the EGFR and LGR5 proteins. Published in Nature Cancer, the study showed that MCLA-158 blocks
Institute for Research in Biomedicine
Institute_for_Research_in_Biomedicine
Family of proteins
(LGR4, GPR48) Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5, GPR49) Leucine-rich repeat-containing G protein-coupled receptor 6 (LGR6)
Rhodopsin-like_receptors
exists within the renal capsule. Using in vivo lineage tracing techniques, Lgr5+ cells were found to contribute to the nephron, specifically to the ascending
Renal_stem_cell
Hypothesis in biology
Vries, R; van den Born, M; van de Wetering, M; Clevers, H (16 March 2011). "Lgr5 intestinal stem cells have high telomerase activity and randomly segregate
Immortal DNA strand hypothesis
Immortal_DNA_strand_hypothesis
Belgian physician
PMID 20154679. S2CID 19815740. Sánchez-Danés, A (2018). "A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy". Nature
Cédric_Blanpain
Mammalian protein found in humans
"Identification of stem cells in small intestine and colon by marker gene Lgr5". Nature. 449 (7165): 1003–1007. Bibcode:2007Natur.449.1003B. doi:10.1038/nature06196
Catenin_beta-1
Cancer cells with features of normal cells
This strategy, for instance, was instrumental for identifying the so-called Lgr5+ compartment as a cancer stem cell compartment in liver cancer and showing
Cancer_stem_cell
Protein-coding gene in the species Homo sapiens
Lee JY, et al. (January 2012). "The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations". Proceedings of the National
KLF4
Protein-coding gene in the species Homo sapiens
"Identification of stem cells in small intestine and colon by marker gene Lgr5". Nature. 449 (7165): 1003–1007. Bibcode:2007Natur.449.1003B. doi:10.1038/nature06196
Homeobox_protein_CDX-1
Institute of Developmental Biology, Utrecht, Netherlands "Wnt signaling, Lgr5 stem cells and cancer" 8 55 May 26, 2011 Jeffery Errington Newcastle University
Mendel_Lectures
British cancer researcher
In collaboration with Hans Clevers's laboratory, Owen's group showed that Lgr5-positive cells are an efficient cell of tumourigenesis. Within the same study
Owen_Sansom
Protein-coding gene in the species Homo sapiens
NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor". The EMBO Journal. 39 (3) e102771. doi:10.15252/embj.2019102771
NEDD4
Microfluidic bioengineered 3D-model
Kujala, Pekka; Peters, Peter J.; Clevers, Hans (29 March 2009). "Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche"
Intestine-on-a-chip
HGNC:18712; Q8N135 8686 LGMN HGNC:9472; Q99538 8687 LGR4 HGNC:13299; Q9BXB1 8688 LGR5 HGNC:4504; O75473 8689 LGR6 HGNC:19719; Q9HBX8 8690 LGSN HGNC:21016; Q5TDP6
List of human protein-coding genes 4
List_of_human_protein-coding_genes_4
Cytokeratin 19, K19) Kit L-selectin (CD62L) Lamin A/C Lewis X antigen (Le(X)) LeX Lgr5 Lrp4 MCM2 MCSP Metallothionein (MT) crypt-restricted immunopositivity indices
Stem_cell_marker
LGR5
LGR5
LGR5
LGR5
Boy/Male
Indian
A helper
Boy/Male
Hindu, Indian, Sanskrit
Gold
Boy/Male
Indian, Punjabi, Sikh
Best of All
Boy/Male
Hindu, Indian
Lord Ganesh
Boy/Male
British, English
From the Yard on a Hill
Girl/Female
Gujarati, Indian
God Like
Boy/Male
Australian, Danish, Dutch, Finnish, French, German, Hebrew, Japanese, Swedish, Swiss, Teutonic
Rules his Household; Home Ruler; Form of Henry; Ruler of the Home; House Owner; Lord of the Manor; Similar to Henry; Ruler of the Enclosure
Girl/Female
Tamil
Vamanie | வாமாஂநீà®
Power of Sky, Land and water
Female
Egyptian
, the name of two Egyptian ladies.
Surname or Lastname
English
English : probably a variant of Salthouse (see Salters).
LGR5
LGR5
LGR5
LGR5
LGR5