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SPHINGOSINE

  • Sphingosine
  • Chemical compound

    important phospholipid. Sphingosine can be phosphorylated in vivo via two kinases, sphingosine kinase type 1 and sphingosine kinase type 2. This leads

    Sphingosine

    Sphingosine

  • Sphingosine-1-phosphate
  • Signaling sphingolipid

    Sphingosine-1-phosphate (S1P) is a signaling sphingolipid, also known as lysosphingolipid. It is also referred to as a bioactive lipid mediator. Sphingolipids

    Sphingosine-1-phosphate

    Sphingosine-1-phosphate

  • Sphingosine kinase
  • Class of enzymes

    from the precursor sphingolipid sphingosine. Sphingolipid metabolites, such as ceramide, sphingosine and sphingosine-1-phosphate, are lipid second messengers

    Sphingosine kinase

    Sphingosine kinase

    Sphingosine_kinase

  • Sphingosine kinase 1
  • Protein-coding gene in the species Homo sapiens

    Sphingosine kinase 1 is an enzyme that in humans is encoded by the SPHK1 gene. Sphingosine kinase 1 phosphorylates sphingosine to sphingosine-1-phosphate

    Sphingosine kinase 1

    Sphingosine kinase 1

    Sphingosine_kinase_1

  • SPHK2
  • Protein-coding gene in the species Homo sapiens

    kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including

    SPHK2

    SPHK2

    SPHK2

  • Sphingosine-1-phosphate receptor
  • The sphingosine-1-phosphate receptors are a class of G protein-coupled receptors that are targets of the lipid signalling molecule Sphingosine-1-phosphate

    Sphingosine-1-phosphate receptor

    Sphingosine-1-phosphate receptor

    Sphingosine-1-phosphate_receptor

  • S1PR1
  • Protein and coding gene in humans

    Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1PR1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded

    S1PR1

    S1PR1

    S1PR1

  • S1PR2
  • Protein and coding gene in humans

    Sphingosine-1-phosphate receptor 2, also known as S1PR2 or S1P2, is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling

    S1PR2

    S1PR2

    S1PR2

  • Sphingolipid
  • Family of chemical compounds

    sphingoid bases, which are a set of aliphatic amino alcohols that includes sphingosine. They were discovered in brain extracts in the 1870s and were named after

    Sphingolipid

    Sphingolipid

    Sphingolipid

  • Fingolimod
  • Chemical compound

    medication, used for the treatment of multiple sclerosis. Fingolimod is a sphingosine-1-phosphate receptor modulator, which sequesters lymphocytes in lymph

    Fingolimod

    Fingolimod

    Fingolimod

  • Ceramide
  • Family of waxy lipid molecules

    Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid joined by an amide bond. Ceramides are found in high

    Ceramide

    Ceramide

    Ceramide

  • Sphingosine beta-galactosyltransferase
  • Class of enzymes

    Sphingosine beta-galactosyltransferase (EC 2.4.1.23) is an enzyme that catalyzes the chemical reaction UDP-galactose +   sphingosine     UDP       psychosine

    Sphingosine beta-galactosyltransferase

    Sphingosine_beta-galactosyltransferase

  • Dosergoside
  • Pharmaceutical compound

    International Nonproprietary Name), also known as lyrgosin or N-(dihydrolysergyl)sphingosine, is a dopamine agonist of the ergoline and lysergamide families which

    Dosergoside

    Dosergoside

    Dosergoside

  • Sphingosine cholinephosphotransferase
  • enzymology, a sphingosine cholinephosphotransferase (EC 2.7.8.10) is an enzyme that catalyzes the chemical reaction CDP-choline + sphingosine ⇌ {\displaystyle

    Sphingosine cholinephosphotransferase

    Sphingosine_cholinephosphotransferase

  • Sphingosine-1-phosphate receptor modulator
  • Drug class

    Sphingosine-1-phosphate receptor modulators are a class of drugs that interact with S1P receptors, a family of G protein-coupled receptors involved in

    Sphingosine-1-phosphate receptor modulator

    Sphingosine-1-phosphate receptor modulator

    Sphingosine-1-phosphate_receptor_modulator

  • 2-Hydroxyacylsphingosine 1-beta-galactosyltransferase
  • Class of enzymes

    UDP-galactose + 2-(2-hydroxyacyl)sphingosine ⇌ {\displaystyle \rightleftharpoons } UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine Thus, the two substrates

    2-Hydroxyacylsphingosine 1-beta-galactosyltransferase

    2-Hydroxyacylsphingosine_1-beta-galactosyltransferase

  • Kinase
  • Enzyme catalyzing transfer of phosphate groups onto specific substrates

    coordinated for this purpose. Sphingosine kinase (SK) is a lipid kinase that catalyzes the conversion of sphingosine to sphingosine-1-phosphate (S1P). Sphingolipids

    Kinase

    Kinase

    Kinase

  • SGPP1
  • Protein-coding gene in the species Homo sapiens

    Sphingosine-1-phosphate phosphatase 1 is an enzyme that in humans is encoded by the SGPP1 gene. ENSG00000285281 GRCh38: Ensembl release 89: ENSG00000126821

    SGPP1

    SGPP1

    SGPP1

  • SGPL1
  • Enzyme

    Sphingosine-1-phosphate lyase 1 is an enzyme that, in humans, is encoded by the SGPL1 gene. A mutation in the gene can lead to sphingosine phosphate lyase

    SGPL1

    SGPL1

    SGPL1

  • S1PR3
  • Protein and coding gene in humans

    Sphingosine-1-phosphate receptor 3 also known as S1PR3 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule

    S1PR3

    S1PR3

    S1PR3

  • Etrasimod
  • Medication

    that is used for the treatment of ulcerative colitis. It is a selective sphingosine-1-phosphate (S1P) receptor modulator that modifies the activity of the

    Etrasimod

    Etrasimod

    Etrasimod

  • Sphingosine phosphate lyase insufficiency syndrome
  • Medical condition

    sphingosine phosphate lyase insufficiency syndrome (SPLIS) is a rare autosomal recessive disorder caused by mutations in the SGPL1 gene located on human

    Sphingosine phosphate lyase insufficiency syndrome

    Sphingosine phosphate lyase insufficiency syndrome

    Sphingosine_phosphate_lyase_insufficiency_syndrome

  • Sphinganine
  • Chemical compound

    sphingolipid class with molecular formula C18H39NO2. Via the action of sphingosine kinase enzymes, it is converted to dihydrosphingosine 1-phosphate (sphinganine

    Sphinganine

    Sphinganine

  • Sphingosine N-acyltransferase
  • In enzymology, sphingosine N-acyltransferases (ceramide synthases (CerS), EC 2.3.1.24) are enzymes that catalyze the chemical reaction of synthesis of

    Sphingosine N-acyltransferase

    Sphingosine N-acyltransferase

    Sphingosine_N-acyltransferase

  • Lipid signaling
  • Biological signaling using lipid molecules

    that hydrolyze the phosphocholine group from the sphingosine backbone. Alternatively, this sphingosine-derived lipid (sphingolipid) can be synthesized

    Lipid signaling

    Lipid signaling

    Lipid_signaling

  • Siponimod
  • Chemical compound

    Siponimod, sold under the brand name Mayzent, is a selective sphingosine-1-phosphate receptor modulator for oral use that is used for multiple sclerosis

    Siponimod

    Siponimod

    Siponimod

  • Ceramidase
  • Type of enzyme

    acids from ceramide, producing sphingosine (SPH) which in turn is phosphorylated by a sphingosine kinase to form sphingosine-1-phosphate (S1P). Ceramide

    Ceramidase

    Ceramidase

  • S1PR5
  • Protein-coding gene in the species Homo sapiens

    Sphingosine-1-phosphate receptor 5 also known as S1PR5 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule

    S1PR5

    S1PR5

    S1PR5

  • Biosynthesis
  • Process where substrates are converted into more complex products in living organisms

    group of a sphingosine backbone. These ceramides are synthesized from the acylation of sphingosine. The biosynthetic pathway for sphingosine is found below:

    Biosynthesis

    Biosynthesis

  • Smooth muscle
  • Involuntary non-striated muscle

    muscle contraction. When transmural pressure increases, sphingosine kinase 1 phosphorylates sphingosine to S1P, which binds to the S1P2 receptor in plasma

    Smooth muscle

    Smooth muscle

    Smooth_muscle

  • Ponesimod
  • Medication for the treatment of multiple sclerosis

    Ponvory, is a medication for the treatment of multiple sclerosis. It is a sphingosine-1-phosphate receptor modulator. The most common side effects include

    Ponesimod

    Ponesimod

    Ponesimod

  • Cenerimod
  • Chemical compound

    evaluated for the treatment of systemic lupus erythematosus. It is a sphingosine-1-phosphate receptor modulator. "Cenerimod - Idorsia Pharmaceuticals"

    Cenerimod

    Cenerimod

    Cenerimod

  • Staphylococcus epidermidis
  • Species of bacterium

    epidermidis production of ceramides - a lipid that includes sphingosine and sphingosine-1-phosphate. This lipid, both obtains nutrients essential for

    Staphylococcus epidermidis

    Staphylococcus epidermidis

    Staphylococcus_epidermidis

  • HEK 293 cells
  • Cell line derived from human embryonic kidney cells

    (March 2001). "Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors". European Journal

    HEK 293 cells

    HEK 293 cells

    HEK_293_cells

  • Sphingomyelin
  • Class of chemical compounds

    head group, a sphingosine, and a fatty acid. It is one of the few membrane phospholipids not synthesized from glycerol. The sphingosine and fatty acid

    Sphingomyelin

    Sphingomyelin

    Sphingomyelin

  • 4-Deoxypyridoxine
  • Chemical compound

    4-Deoxypyridoxine has also been described as an inhibitor of sphingosine-1-phosphate lyase. The inhibition of sphingosine-1-phosphate lyase by 4-deoxypyridoxine has been

    4-Deoxypyridoxine

    4-Deoxypyridoxine

    4-Deoxypyridoxine

  • Sarah Spiegel (biologist)
  • American biologist

    Virginia Commonwealth University (VCU). In the mid-1990s she discovered the sphingosine-1-phosphate (S1P) molecule, a lipid which has been identified as a signaler

    Sarah Spiegel (biologist)

    Sarah_Spiegel_(biologist)

  • Ozanimod
  • Medication

    of relapsing multiple sclerosis and ulcerative colitis. It acts as a sphingosine-1-phosphate receptor (S1PR) agonist, sequestering lymphocytes to peripheral

    Ozanimod

    Ozanimod

    Ozanimod

  • Lysophospholipid receptor
  • Type of G protein-coupled receptor

    lysophospholipid extracellular signaling molecules, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). The term lysophospholipid (LPL) refers to any phospholipid

    Lysophospholipid receptor

    Lysophospholipid_receptor

  • Myriocin
  • Chemical compound

    very potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Due to this property, it is used in biochemical research

    Myriocin

    Myriocin

    Myriocin

  • Find-me signals
  • recruitment of phagocytes to apoptotic cells is not yet known. Sphingosine kinase 1 and sphingosine kinase 2 have been linked to S1P generation during apoptosis

    Find-me signals

    Find-me_signals

  • FIASMA
  • it cleaves sphingomyelin to ceramide and sphingosine, the latter of which is then phosphorylated to sphingosine-1-phosphate. These metabolites, and subsequent

    FIASMA

    FIASMA

  • Cisplatin
  • Chemical compound and pharmaceutical drug

    (half-inhibition = 30 μg/mL) and reversible. Cisplatin can increase levels of sphingosine-1-phosphate in the central nervous system, contributing to the development

    Cisplatin

    Cisplatin

    Cisplatin

  • Opaganib
  • Chemical compound

    Opaganib (ABC294640) is a drug which acts as an inhibitor of the enzyme sphingosine kinase 2, dihydroceramide desaturase (DES1), and glucosylceramide synthase

    Opaganib

    Opaganib

    Opaganib

  • Membrane lipid
  • Lipid molecules on cell membrane

    Sphingosine is an amino alcohol that contains a long, unsaturated hydrocarbon chain. In sphingomyelin and glycolipids, the amino group of sphingosine

    Membrane lipid

    Membrane lipid

    Membrane_lipid

  • Lipid
  • Substance of biological origin that is soluble in nonpolar solvents

    compounds. The major sphingoid base of mammals is commonly referred to as sphingosine. Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid

    Lipid

    Lipid

    Lipid

  • Vitamin B6
  • Class of chemically related vitamins

    dependent on vitamin B6 because sphingosine-1-phosphate lyase, the enzyme responsible for breaking down sphingosine-1-phosphate, is also PLP-dependent

    Vitamin B6

    Vitamin B6

    Vitamin_B6

  • Fumonisin B1
  • Chemical compound

    via sphingosine produced by the breakdown of ceramide by ceramidase. The inhibition results in increased concentrations of sphinganine, sphingosine and

    Fumonisin B1

    Fumonisin B1

    Fumonisin_B1

  • Glycosphingolipid
  • Lipid with a carbohydrate attached to a ceramide

    Glycosphingolipids are a subtype of glycolipids containing the amino alcohol sphingosine. They may be considered as sphingolipids with an attached carbohydrate

    Glycosphingolipid

    Glycosphingolipid

  • ASAH2
  • Protein-coding gene in the species Homo sapiens

    PMID 15946935. Tani M, Sano T, Ito M, Igarashi Y (2006). "Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets". J. Lipid Res. 46

    ASAH2

    ASAH2

    ASAH2

  • Phosphatidic acid
  • Class of lipid compounds

    lipid, recruiting cytosolic proteins to appropriate membranes (e.g., sphingosine kinase 1). PA plays very important role in phototransduction in Drosophila

    Phosphatidic acid

    Phosphatidic_acid

  • List of immune cells
  • Pawlak EA, Gomez S, Jaspers I, Allbritton NL (April 2015). "Analysis of sphingosine kinase activity in single natural killer cells from peripheral blood"

    List of immune cells

    List_of_immune_cells

  • CYM50308
  • Pharmaceutical compound

    CYM50308 (ML248) is a drug which acts as a selective agonist at the sphingosine-1-phosphate receptor S1PR4. It is used for research into the structure

    CYM50308

    CYM50308

    CYM50308

  • Alpha-2 adrenergic receptor
  • Protein family

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Alpha-2 adrenergic receptor

    Alpha-2 adrenergic receptor

    Alpha-2_adrenergic_receptor

  • N,N-Dimethylsphingosine
  • Chemical compound

    N,N-Dimethylsphingosine (also known as DMS) is an inhibitor of sphingosine kinase. In rats with neuropathic pain, the natural metabolite DMS is unregulated

    N,N-Dimethylsphingosine

    N,N-Dimethylsphingosine

  • Palmitoyl-CoA
  • Chemical compound

    Alternatively, palmitoyl-CoA is used as a substrate in the biosynthesis of sphingosine (this biosynthetic pathway does not require transfer into mitochondria)

    Palmitoyl-CoA

    Palmitoyl-CoA

  • Safingol
  • Chemical compound

    Safingol is also a putative inhibitor of sphingosine kinase 1 (SphK), which catalyzes the production of sphingosine 1-phosphate (S1P), an important mediator

    Safingol

    Safingol

  • Farber disease
  • Medical condition

    enzyme. Acid ceramidase is responsible for breaking down ceramide into sphingosine and fatty acid. When the enzyme is deficient, this leads to an accumulation

    Farber disease

    Farber_disease

  • Muscarinic acetylcholine receptor
  • Acetylcholine receptors named for their selective binding of muscarine

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Muscarinic acetylcholine receptor

    Muscarinic acetylcholine receptor

    Muscarinic_acetylcholine_receptor

  • Lysophosphatidic acid
  • Chemical compound

    the synthesis of phosphatidic acids. Autotaxin GPR35 Phosphatidic acid Sphingosine-1-phosphate Gintonin van Corven, Emile J.; Groenink, Alida; Jalink, Kees;

    Lysophosphatidic acid

    Lysophosphatidic acid

    Lysophosphatidic_acid

  • Cerebroside
  • Lipid classification

    glycosidically to the terminal OH group of ceramide are defined as cerebrosides. Sphingosine is the main long-chain base present in ceramide. Galactosylceramide is

    Cerebroside

    Cerebroside

    Cerebroside

  • Ezrin
  • Protein-coding gene in the species Homo sapiens

    process leukocyte cell-cell adhesion regulation of organelle assembly sphingosine-1-phosphate receptor signaling pathway negative regulation of p38MAPK

    Ezrin

    Ezrin

    Ezrin

  • Lysophosphatidylcholine
  • Class of compounds

    Antagonists: H2L-5186303 H2L-5765834 Ki-16425 TC-LPA5 4 VPC-32183 S1PRTooltip Sphingosine-1-phosphate receptor Agonists: Amiselimod Cenerimod Ceralifimod CS-2100

    Lysophosphatidylcholine

    Lysophosphatidylcholine

    Lysophosphatidylcholine

  • Ulcerative colitis
  • Inflammatory bowel disease that causes ulcers in the colon

    to MAdCAM-1. While the medications ozanimod and etrasimod inhibit the sphingosine-1-phosphate receptor to prevent T-cell migration into the efferent lymphatic

    Ulcerative colitis

    Ulcerative colitis

    Ulcerative_colitis

  • Marginal-zone B cell
  • Type of immune cell

    CXCR5/CXCL13 signaling is required for MZ B cells to enter the follicle, Sphingosine-1-phosphate signaling is required for them to exit from the follicle

    Marginal-zone B cell

    Marginal-zone B cell

    Marginal-zone_B_cell

  • H. E. Carter
  • American biochemist (1910–2007)

    structure and synthesis of sphingosine. Carter, H. E., and C. B. Hirschberg. 1968. Phytosphingosines and branched sphingosines in kidney. Biochemistry.

    H. E. Carter

    H._E._Carter

  • Serine
  • Amino acid

    Antagonists: H2L-5186303 H2L-5765834 Ki-16425 TC-LPA5 4 VPC-32183 S1PRTooltip Sphingosine-1-phosphate receptor Agonists: Amiselimod Cenerimod Ceralifimod CS-2100

    Serine

    Serine

    Serine

  • S1PR4
  • Protein-coding gene in the species Homo sapiens

    Sphingosine-1-phosphate receptor 4 also known as S1PR4 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule

    S1PR4

    S1PR4

    S1PR4

  • EMR1
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    EMR1

    EMR1

    EMR1

  • Dopamine receptor D3
  • Subtype of Dopamine Receptor

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Dopamine receptor D3

    Dopamine receptor D3

    Dopamine_receptor_D3

  • G protein-coupled receptor
  • Class of cell surface receptors coupled to G-protein-associated intracellular signaling

    PMC 7088898. PMID 32259074. Sharma N, Akhade AS, Qadri A (April 2013). "Sphingosine-1-phosphate suppresses TLR-induced CXCL8 secretion from human T cells"

    G protein-coupled receptor

    G protein-coupled receptor

    G_protein-coupled_receptor

  • Starfish
  • Class of echinoderms, marine animal

    including steroidal derivatives of cholesterol, and fatty acid amides of sphingosine. The steroids are mostly saponins, known as asterosaponins, and their

    Starfish

    Starfish

    Starfish

  • Chemotherapy
  • Treatment of cancer using drugs that inhibit cell division or kill cells

    protective effect in vivo in humans, but some studies show no such effect. Sphingosine-1-phosphate (S1P) has shown similar effect, but its mechanism of inhibiting

    Chemotherapy

    Chemotherapy

    Chemotherapy

  • Cyclic GMP-AMP synthase
  • Cytosolic DNA sensor

    Deoxycytidine PFP Diacylglycerol Phosphoinositide 3 Class I PI 3 Class II PI 3 Sphingosine Glucose-1,6-bisphosphate synthase 2.7.2: COOH acceptor Phosphoglycerate

    Cyclic GMP-AMP synthase

    Cyclic GMP-AMP synthase

    Cyclic_GMP-AMP_synthase

  • Vasopressin receptor
  • G protein-coupled receptor

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Vasopressin receptor

    Vasopressin_receptor

  • ASAH1
  • Protein-coding gene in the species Homo sapiens

    encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal

    ASAH1

    ASAH1

    ASAH1

  • MAS1
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    MAS1

    MAS1

    MAS1

  • ATC code L04
  • Pharmaceutical drug classification

    ATC code L04 Immunosuppressants is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes

    ATC code L04

    ATC_code_L04

  • Frizzled-5
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Frizzled-5

    Frizzled-5

    Frizzled-5

  • Alpha-1B adrenergic receptor
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Alpha-1B adrenergic receptor

    Alpha-1B adrenergic receptor

    Alpha-1B_adrenergic_receptor

  • GPR63
  • Protein-coding gene in the species Homo sapiens

    PMID 12477932. Niedernberg A, Tunaru S, Blaukat A, et al. (2004). "Sphingosine 1-phosphate and dioleoylphosphatidic acid are low affinity agonists for

    GPR63

    GPR63

    GPR63

  • Beta-1 adrenergic receptor
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Beta-1 adrenergic receptor

    Beta-1 adrenergic receptor

    Beta-1_adrenergic_receptor

  • SK-1
  • Topics referred to by the same term

    spacesuit sK1 (program), a fork of the Skencil vector graphics editor Sphingosine kinase 1, a protein SK1 (film), a 2014 French film VR Class Sk1, a locomotive

    SK-1

    SK-1

  • LGR4
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    LGR4

    LGR4

    LGR4

  • Tachykinin receptor 1
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Tachykinin receptor 1

    Tachykinin receptor 1

    Tachykinin_receptor_1

  • G protein-coupled bile acid receptor
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    G protein-coupled bile acid receptor

    G protein-coupled bile acid receptor

    G_protein-coupled_bile_acid_receptor

  • Lysophosphatidic acid receptor
  • Index of articles associated with the same name

    6 (LPAR6; formerly known as GPR87, P2RY5) Lysophospholipid receptor Sphingosine-1-phosphate receptor P2Y receptor This set index article includes a list

    Lysophosphatidic acid receptor

    Lysophosphatidic_acid_receptor

  • The West Wing season 3
  • Season of television series

    have dinner with a group of her scientist friends who speculate that sphingosine kinase could lead to a cure for cancer. As a result, the President demands

    The West Wing season 3

    The_West_Wing_season_3

  • Serine C-palmitoyltransferase
  • Class of enzymes

    3-dehydro-D-sphinganine, and CO2. This reaction is a key step in the biosynthesis of sphingosine which is a precursor of many other sphingolipids. This enzyme participates

    Serine C-palmitoyltransferase

    Serine C-palmitoyltransferase

    Serine_C-palmitoyltransferase

  • GSL
  • Topics referred to by the same term

    Glycosphingolipids, a subtype of glycolipids containing the amino alcohol sphingosine GNU Scientific Library, a software library for applied mathematics and

    GSL

    GSL

  • Membrane androgen receptor
  • Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Membrane androgen receptor

    Membrane_androgen_receptor

  • Neuromedin B receptor
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Neuromedin B receptor

    Neuromedin B receptor

    Neuromedin_B_receptor

  • Somatostatin receptor 1
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Somatostatin receptor 1

    Somatostatin receptor 1

    Somatostatin_receptor_1

  • Melatonin receptor
  • Type of cell surface receptor

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Melatonin receptor

    Melatonin_receptor

  • Jason Cyster
  • interaction dynamics in immunity, and the role of lipid mediators such as sphingosine-1-phosphate (S1P) in immune cell trafficking. He is currently a professor

    Jason Cyster

    Jason_Cyster

  • Melanocortin 5 receptor
  • Protein found in humans

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Melanocortin 5 receptor

    Melanocortin 5 receptor

    Melanocortin_5_receptor

  • Neurotensin receptor 1
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    Neurotensin receptor 1

    Neurotensin receptor 1

    Neurotensin_receptor_1

  • GPR56
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    GPR56

    GPR56

    GPR56

  • Phosphatidate phosphatase
  • Class of enzymes

    CDP-diacylglycerol with inositol), and cardiolipin. It is down-regulated by sphingosine and dihydrosphingosine. This makes sense in the context of the discussion

    Phosphatidate phosphatase

    Phosphatidate phosphatase

    Phosphatidate_phosphatase

  • GABBR1
  • Protein-coding gene in the species Homo sapiens

    Lysophosphatidic acid 1 2 3 4 5 6 Lysophospholipid 1 2 3 4 5 6 7 8 Oxoglutarate PAF Sphingosine-1-phosphate 1 2 3 4 5 Succinate Peptide Neuropeptide B/W 1 2 FF 1 2 S

    GABBR1

    GABBR1

    GABBR1

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Online names & meanings

  • Gamaliel
  • Boy/Male

    Biblical Hebrew

    Gamaliel

    Recompense of God, camel of God.

  • LÍADÁIN
  • Female

    Irish

    LÍADÁIN

    Variant spelling of Irish Gaelic Líadan, LÍADÁIN means "grey lady."

  • MAGAHET
  • Male

    Chamoru

    MAGAHET

    , certainly, truly.

  • Dahi |
  • Boy/Male

    Muslim

    Dahi |

    Lion, Rapid

  • Tabish
  • Girl/Female

    Indian

    Tabish

    Brilliance, Warmth

  • Celestine
  • Girl/Female

    American, Australian, British, Christian, English, French, German, Latin, Swedish

    Celestine

    Heavenly; Divine; Of Sky

  • Ghawani
  • Boy/Male

    Arabic

    Ghawani

    Modest; Singer; Chaste

  • Kathiresan
  • Boy/Male

    Hindu, Indian, Tamil

    Kathiresan

    Sun Shine

  • UNNUR
  • Female

    Icelandic

    UNNUR

    Icelandic form of Old Norse Unnr, UNNUR means "wave."

  • Dalip
  • Boy/Male

    Hindu, Indian, Punjabi, Sikh

    Dalip

    King; King of Kings

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