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Chemical group attached to backbone
Branch Side-chain Pendant chain An oligomeric or polymeric offshoot from a macromolecular chain. Notes An oligomeric branch may be termed a short-chain branch
Side_chain
Topics referred to by the same term
Side-chain, side chain, or sidechain may refer to: Side chain, a chemical group attached to the main chain or backbone of a molecule, such as a protein
Side-chain
Audio signal processing operation
split; one copy is sent to a variable-gain amplifier and the other to a side-chain where the signal level is measured and a circuit controlled by the measured
Dynamic_range_compression
Chemical changes in proteins following their translation from mRNA
hormones. Post-translational modifications can occur on the amino acid side chains or at the protein's C- or N- termini. They can expand the chemical set
Post-translational modification
Post-translational_modification
Generally accepted theory published in 1900 to explain immune response in living cells
The side-chain theory (German, Seitenkettentheorie) is a theory proposed by Paul Ehrlich (1854–1915) to explain the immune response in living cells. Ehrlich
Side-chain_theory
Class of extremely unreactive, inert and fire-resistant polymers
classification of LCPs. Main chain liquid crystal polymers (MCLCPs) have liquid crystal cores in the main chain. By contrast, side chain liquid crystal polymers
Liquid-crystal_polymer
Drugs used to treat bone disorders
side chain was the key to a more potent drug. Later it became apparent that the nitrogen does not necessarily have to be connected to an alkyl chain but
Discovery and development of bisphosphonates
Discovery_and_development_of_bisphosphonates
Organic compounds containing amine and carboxylic groups
amino acids, etc.); other categories relate to polarity, ionization, and side-chain group type (aliphatic, acyclic, aromatic, polar, etc.). In the form of
Amino_acid
Class of molecules found in the outer membrane of Gram-negative bacteria
within an LPS is referred to as the O antigen, O polysaccharide, or O side-chain of the bacteria. The O antigen is attached to the core oligosaccharide
Lipopolysaccharide
Class of pharmaceutical drugs
and cefotetan. This is thought to be due to the methylthiotetrazole side-chain of these cephalosporins, which blocks the enzyme vitamin K epoxide reductase
Cephalosporin
Mammalian protein found in humans
Cholesterol side-chain cleavage enzyme is commonly referred to as P450scc, where "scc" is an abbreviation for side-chain cleavage, and more properly named
Cholesterol side-chain cleavage enzyme
Cholesterol_side-chain_cleavage_enzyme
Coupling for railway vehicles
single central buffer with a chain underneath. Sometimes there are two chains, one on each side of the coupler. The chain usually contains a screw-adjustable
Buffers_and_chain_coupler
Amino acid that is incorporated biosynthetically into proteins during translation
symbols, the three-letter symbols, and the chemical properties of the side chains of the standard amino acids. The masses listed are based on weighted
Proteinogenic_amino_acid
Type of biological prediction
chemistry of the side chain, which also plays an important structural role. Glycine takes on a special position, as it has the smallest side chain, only one
Protein_structure_prediction
Chemical compound
carboxamide). K⁴ – L-lysine with the amino group at position 6 modified with a side chain; specifically, (AEEA)-(γ-Glu)-(C20 diacid) (where AEEA is
Retatrutide
Amino acids not naturally encoded in the genome
from their native analogs via modifications such as amine alkylation, side chain substitution, structural bond extension cyclization, and isosteric replacements
Non-proteinogenic_amino_acids
Group of antibiotics derived from fungi
G. 6-APA contains the beta-lactam core of penicillin G, but with the side chains stripped off; 6-APA is a useful precursor for manufacturing other penicillins
Penicillin
German physician and scientist (1854–1915)
surplus of side chains, these might also be released into the blood as antibodies. In the following years Ehrlich expanded his side chain theory using
Paul_Ehrlich
Fat-soluble vitamers
of the carbon tail and the number of repeating isoprene units in the side chain (see figures in § Chemistry). Plant-sourced forms are primarily vitamin
Vitamin_K
Drugs acting on the estrogen receptor
triphenylethylene moiety and the side chain are required for tamoxifen binding to the ER, whereas for 4-hydroxytamoxifen, the side chain, and the phenyl-propene
Selective estrogen receptor modulator
Selective_estrogen_receptor_modulator
System for naming organic chemical compounds
should be used. Identification of the side-chains. Side chains are the carbon chains that are not in the parent chain, but are branched off from it. Identification
IUPAC nomenclature of organic chemistry
IUPAC_nomenclature_of_organic_chemistry
Substance composed of macromolecules with repeating structural units
chain. In the case of unbranched polyethylene, this chain is a long-chain n-alkane. There are also branched macromolecules with a main chain and side
Polymer
Medical condition
20,22-desmolase, but now identified as cytochrome P450scc (cholesterol side chain cleavage enzyme). However, few cases of lipoid CAH due to a mutation and
Lipoid congenital adrenal hyperplasia
Lipoid_congenital_adrenal_hyperplasia
Collection of data on conformations of a given protein's amino acid side chains
of the discrete conformations (known as rotamers) of the amino acid side chains in proteins as a function of the backbone dihedral angles φ and ψ of
Backbone-dependent rotamer library
Backbone-dependent_rotamer_library
Polymer with a backbone of one composite and random branches of another composite
the main chain as side-chains, these side-chains having constitutional or configurational features that differ from those in the main chain. comb macromolecule:
Graft_polymer
Chemical compound
histidyl. At neutral or physiological pH, the imidazole side chain is neutral. The imidazole side chain in histidine has a pKa of approximately 6.0. Thus,
Histidine
Group of vitamins and bacterial metabolites
products or fermented foods. The number n of isoprenyl units in their side chain differs and ranges from 4 to 13, hence vitamin K2 consists of various
Vitamin_K2
Biochemical cofactor and antioxidant
structure of CoQ10 consists of a benzoquinone moiety and an isoprenoid side chain, with the "10" referring to the number of isoprenyl chemical subunits
Coenzyme_Q10
Species of plant
differences in the side chains of the chemicals in these plants. In general, poison ivy has a C15 side chain, poison oak has a C17 side chain and poison sumac
Toxicodendron_vernix
Series of connected links which are typically made of metal
Silent chain Rope chain Twisted link chain Wheat chain Single jack chain Double jack chain Stud link chain Ladder link chain Foxtail chain Rolo chain Roller
Chain
Class of plant cell wall polysaccharides
residues in the main chains. As for the side chains, D-galactopyranose residues tend to be 6-linked to both types as the single side chains with various amount
Hemicellulose
Artifact of compression in audio
cymbals on Portishead's "Pedestal". Side-chain pumping is a more advanced technique using a compressor's side-chain feature which, "uses the amplitude
Pumping_(audio)
Production of peptides
strategies are usually necessary to prevent undesirable side reactions with the various amino acid side chains. Chemical peptide synthesis most commonly starts
Peptide_synthesis
Visual representation of allowable protein conformations
hydrogen atom for its side chain, with a much smaller van der Waals radius than the CH3, CH2, or CH group that starts the side chain of all other amino acids
Ramachandran_plot
Class of 8 chemically related vitamins
can donate a hydrogen atom to reduce free radicals, and a hydrophobic side chain that allows for penetration into biological membranes. Both natural and
Vitamin_E
Amino acid with a branched carbon chain
A branched-chain amino acid (BCAA) is an amino acid having an aliphatic side-chain with a branch (a central carbon atom bound to three or more carbon
Branched-chain_amino_acid
Saccharide polymer
of the side chain. Alternately, O-linked oligosaccharides are generally attached to threonine or serine on the alcohol group of the side chain. Not all
Oligosaccharide
Class of chemical compounds
chlorofluorocarbon (CFC) replacements introduced as a result of the Montreal Protocol. Side-chain fluorinated polymers (SCFPs), in which fluorotelomers are attached to
Perfluoroalkyl carboxylic acids
Perfluoroalkyl_carboxylic_acids
Biomolecule consisting of chains of amino acid residues
variable side chain. Only proline differs from this basic structure as its side chain is cyclical, bonding to the amino group, limiting protein chain flexibility
Protein
Steroid acid in the bile of animals
composed of a steroid structure with four rings, a five- or eight-carbon side-chain terminating in a carboxylic acid, and several hydroxyl groups, the number
Bile_acid
Audio technique that reduces the prominence of sibilance
yielding undesirable effects. With this technique, the signal feeding the side-chain of a dynamic-range compressor is equalized or filtered so that the sibilant
De-essing
Chemical compound
the oxidation of the allyl side chain and the oxidation of the methylenedioxy group. The oxidation of the allyl side chain is mediated by a cytochrome
Safrole
Amino acid
stable amino acid, distinguished by having a single hydrogen atom as its side chain. As one of the 20 proteinogenic amino acids, glycine is a fundamental
Glycine
Structural carbohydrate in the cell walls of land plants and some algae
Main chain monomer: Galacturonic acid (GalA; a sugar acid) Main chain monomer: Rhamnose (Rha) Side chain monomer: Galactose (Gal) Side chain monomer:
Pectin
Highly specific protease
that each side chain of the substrate peptide (P6 to P1') is bound in a complementary site (S6 to S1'). In particular, peptide side chain P6-Glu contacts
TEV_protease
fullerene segments are connected via covalent bonds into a polymeric chain without side or bridging groups. They are called intrinsic polymeric fullerenes
Polyfullerene
Industrial synthesis of chemical substance
ring are eight methyl groups, three propanamide, and three acetamide side chains. The periphery also contains nine stereocenters. The monobasic corrin
Vitamin_B12_total_synthesis
Linear sequence of amino acids in a peptide or protein
peptide bonds to form a long backbone, with the different amino acid side chains protruding along it. In biological systems, proteins are produced during
Protein_primary_structure
Active region of an enzyme
amino acid side chain will repel uncharged substrate. But if the transition state involves the formation of an ion centre then the side chain will now produce
Active_site
Class of enzymes capable of forming isopeptide bonds in certain regions of proteins
groups ( -(C=O)NH2 ) of glutamine residue side chains and the ε-amino groups ( -NH2 ) of lysine residue side chains with subsequent release of ammonia ( NH3 )
Transglutaminase
Angle between two planes in space
"Side Chain Conformation". Dunbrack, RL Jr.; Karplus, M (20 March 1993). "Backbone-dependent rotamer library for proteins. Application to side-chain prediction"
Dihedral_angle
Peptide used as medication
reduced flexibility making the peptide inactive. For example, side chain to side chain cyclization between asparagine (position 8) and lysine (position
Peptide_therapeutics
Attachment of side chains to the backbone chain of a polymer
definitions branched chain: A chain with at least one branch point intermediate between the boundary units. branch (side chain, pendant chain): An oligomer molecule
Branching_(polymer_chemistry)
Digestive enzyme
polypeptides. Chymotrypsin preferentially cleaves peptide amide bonds where the side chain of the amino acid N-terminal to the scissile amide bond (the P1 position)
Chymotrypsin
Cannabinoid agonist compound
component of cannabis, but with the pentyl side chain extended to heptyl. Since it has a longer side chain, its cannabinoid effects are "far higher than
Tetrahydrocannabiphorol
Organic compound involved in immune responses
imidazole ring attached to an ethylamine chain; under physiological conditions, the amino group of the side-chain is protonated. In mammals it is found within
Histamine
Anti-diabetic and anti-obesity medication
glucagon-like peptide-1 (GLP-1), modified with a side chain, and acts as a GLP-1 receptor agonist. The most common side effects include nausea, vomiting, diarrhea
Semaglutide
Concept in biology, precursor to chemotherapy
compounds could also produce such side chains to kill the same microbes. This led him to propose a new concept called "side-chain theory". (Later in 1900, he
Magic_bullet_(medicine)
Proteinogenic amino acid
proteinogenic amino acid with the formula HS−CH2−CH(NH2)−COOH. The thiol side chain in cysteine enables the formation of disulfide bonds, and often participates
Cysteine
Polycyclic organic compound having sterane as a core structure
side chain at C17), in the functional groups attached to the rings and side chain, and in the configuration of groups attached to the rings and chain
Steroid
on the side chain. Corresponding polypseudorotaxanes can also be divided based on the same principle: main chain polypseudorotaxnes or side chain polypseudorotaxanes
Polyrotaxane
Chemical compound
conditions, while the carboxyl group is in the deprotonated −COO− form. The "side chain" from the α carbon connects to the nitrogen forming a pyrrolidine loop
Proline
Amino acid
deprotonated −COO− under physiological conditions. Aspartic acid has an acidic side chain (CH2COOH) which reacts with other amino acids, enzymes and proteins in
Aspartic_acid
Dyes added to identify fuels
modern liquid petroleum dyes are longer alkyl side chain forms of traditional dyes and normally multiple chain length variations of the chromophore are found
Fuel_dye
Peptide chains which contain a circular sequence of bonds
amino end and a side chain, for example in bacitracin; the carboxyl end and a side chain, for example in colistin; or two side chains or more complicated
Cyclic_peptide
Mechanism for connecting rolling stock in a train
in passenger coaches, so the chain was improved by replacing the center link with a screw threaded left-hand on one side and right-hand on the other.
Railway_coupling
Biochemical process
produced: N-linked glycans attached to a nitrogen of asparagine or arginine side-chains. N-linked glycosylation requires participation of a special lipid called
Glycosylation
Study of chemical processes of living organisms
physiologic conditions), a simple hydrogen atom, and a side chain commonly denoted as "–R". The side chain "R" is different for each amino acid of which there
Biochemistry
Pharmaceutical drug class
backbone-NH of Met-318, the aminopyrimidine and side chain hydroxyl of Thr-315, the amide-NH and side chain carboxylate of Glu-286, the carbonyl and backbone-NH
Bcr-Abl tyrosine-kinase inhibitor
Bcr-Abl_tyrosine-kinase_inhibitor
Rational design of new protein molecules
both the side-chains and the backbone. In the simplest models, the protein backbone is kept rigid while some of the protein side-chains are allowed to
Protein_design
Medium-chain fatty acids
MCFAs, apart from the above listed straight chain (unbranched chain) fatty acids, side chain (branched chain) fatty acids also exist. A 2020 systematic
Medium-chain_triglyceride
Bactericidal antibiotics
β-lactamases. Cephalosporin C contains a side-chain which is derived from D-aminoadipic acid. Modification of side chains on the relevant positions has been
Discovery and development of cephalosporins
Discovery_and_development_of_cephalosporins
Amino acid
cheese. It is called tyrosyl when referred to as a functional group or side chain. While tyrosine is generally classified as a hydrophobic amino acid, it
Tyrosine
Α-amino acid that is used in the biosynthesis of proteins
attached to the central carbon atom which also carries a methyl group side chain. Consequently it is classified as a non-polar, aliphatic α-amino acid
Alanine
Amino acid
studies on maritime pine. The amino acid side-chain of arginine consists of a 3-carbon aliphatic straight chain, the distal end of which is capped by a
Arginine
Molecule which moves electron in photosynthesis
4-benzoquinone molecule with a side chain of nine isoprenyl units. There are other forms of plastoquinone, such as ones with shorter side chains like PQ-3 (which has
Plastoquinone
Audio effect
by another signal's presence. Ducking here works through the use of a "side chain" gate. In other words, one track is made quieter (the ducked track) whenever
Ducking
Ubiquitous antioxidant compound in living organisms
synthesized by attaching cysteine to the carboxyl group of the glutamate side chain with a gamma peptide linkage, and to glycine with a normal peptide bond
Glutathione
Method of protein structure prediction using other known proteins
are generally much less accurate than the rest of the model. Errors in side chain packing and position also increase with decreasing identity, and variations
Homology_modeling
Relatively large characteristic segment of a molecule
from the backbone of a hydrocarbon molecule is called a substituent or side chain, which typically can be removed from the molecule and substituted with
Moiety_(chemistry)
Protein structural motif
arises from tetrahedral chemical bonding at the Cα atom; for example, if a side chain points straight up, then the bonds to the C′ must point slightly downwards
Beta_sheet
Organic compound containing the functional group R–CH=O
with the structure R−CH=O. The functional group itself (without the "R" side chain) can be referred to as an aldehyde but can also be classified as a formyl
Aldehyde
Nonsteroidal anti-inflammatory drug (NSAID)
residue Ile434 in COX-1 by Val in COX-2 allows the side chain of Phe518 (a residue at the active side) to open „extra space“, which favors the binding of
Meloxicam
Dynamic range compression technique
recordings. Many citations of this article claim that Beville called it "side-chain" compression, most likely due to a misquoting of a citation of the article
Parallel_compression
Organic compounds of the form >C=N–OH
the imines, with the general formula RR’C=N−OH, where R is an organic side-chain and R' may be hydrogen, forming an aldoxime, or another organic group
Oxime
Polymers of N-substituted glycines
than to the α-carbons (as they are in amino acids). In peptoids, the side chain is connected to the nitrogen of the peptide backbone, instead of the α-carbon
Peptoid
Synthetic route in steroid chemistry
unreactive "double-tetrahydrofuran" side chain, it actually had a much more reactive "ketone spiro acetal" side chain. While the ketone spiro acetal was
Marker_degradation
Chemical compound
3-dimethoxy-5-methyl-6-poly prenyl-1,4-benzoquinol, where the polyprenylated side-chain is 9-10 units long in mammals. Coenzyme Q10 (CoQ10) exists in three redox
Ubiquinol
Covalent bond between amino acids in a protein chain
acids approach each other, with the non-side chain (C1) carboxylic acid moiety of one coming near the non-side chain (N2) amino moiety of the other. One loses
Peptide_bond
In enzymology, a corticosteroid side-chain-isomerase (EC 5.3.1.21) is an enzyme that catalyzes the chemical reaction 11-deoxycorticosterone ⇌ {\displaystyle
Corticosteroid side-chain-isomerase
Corticosteroid_side-chain-isomerase
Pharmaceutical compound
phenethylamine in which the ethylamine side chain has been lengthened by one carbon atom to instead be a propylamine chain. Phenylpropylamine was synthesized
Phenylpropylamine
Chemical compound
is in the deprotonated −COO− form under biological conditions), and a side chain carboxamide, classifying it as a polar (at physiological pH), aliphatic
Asparagine
generates the chemical shifts of both backbone (1H, 13C and 15N) and side chain (1H only) atoms as output (BMRB or Shifty format). The server is optimized
ShiftX
Chemical reaction
Deamidation is a chemical reaction in which an amide functional group in the side chain of the amino acids asparagine or glutamine is removed or converted to
Deamidation
Chemical compound
of a lysine side chain on carbon 1 with a proton on carbon 5. Desmosine is associated with alanine, bonding with it on the N terminal side. It is this
Desmosine
Type of dihedral angle
"Side Chain Conformation". Dunbrack, RL Jr.; Karplus, M (20 March 1993). "Backbone-dependent rotamer library for proteins. Application to side-chain prediction"
Torsion_angle
American independent record label
bands such as Youth of Today, Warzone, Sick of It All, Quicksand, Side By Side, Chain of Strength, Shelter, Judge, No For An Answer, Gorilla Biscuits,
Revelation_Records
Class of chemical compounds
compound that has a catechol (benzene with two hydroxyl side groups next to each other) and a side-chain amine. Catechol can be either a free molecule or a
Catecholamine
Chemical activating melatonin receptors
in position 5 (5-methoxy group) and acylaminoethyl side-chain in position 3. The two side-chains are important for binding to and activating the receptors
Melatonin_receptor_agonist
Chemical coordination complex of an iron ion chelated to a porphyrin
composed of four pyrrole rings with two vinyl and two propionic acid side chains. Heme is biosynthesized in both the bone marrow and the liver. Heme plays
Heme
SIDE CHAIN
SIDE CHAIN
Surname or Lastname
English
English : topographic name for someone who lived on a slope, from Middle English side ‘slope’ (Old English sīde), or a habitational name from Syde in Gloucestershire, named with this word. This name is also established in Ireland.
Boy/Male
Indian
Side
Girl/Female
Latin
Wife of Orion.
Boy/Male
English American French
Wide Island: south of the water; 'from St. Denis'.
Male
English
Masculine short form of English unisex Sidney, SID means "St. Denis."
Male
Native American
Native American Navajo name SIKE means "he sits at home."
Girl/Female
Gaelic Irish Scottish
Boy/Male
Hindu, Indian
Placing Side by Side
Surname or Lastname
English
English : unexplained.
Boy/Male
Muslim
Side
Boy/Male
British, English, Japanese
From the Hide
Female
English
Anglicized form of Irish Gaelic Sadhbh, SIVE means "sweet."
Female
Swedish
Danish and Swedish form of Icelandic Iða, IDE means "industrious."
Girl/Female
Gaelic Irish
Girl/Female
German
warrior.
Girl/Female
Irish
Good.
Surname or Lastname
English
English : unexplained. Perhaps a variant of Sadd.French : habitational name from a place in Hérault called Saddes.French : nickname from Latin sapidus ‘prudent’, ‘wise’.
Boy/Male
Arabic, Muslim, Pakistani
Right Side
Surname or Lastname
English
English : variant of Siddall.
Boy/Male
Hindu, Indian
Direction; Side
SIDE CHAIN
SIDE CHAIN
Boy/Male
Hindu
Beloved, Good Man
Boy/Male
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
Servant of Janaki
Girl/Female
British, English
Faithful
Boy/Male
Norse
Son of Skopta.
Boy/Male
Irish
Strong.
Girl/Female
Indian
Witness, Patriot
Boy/Male
Muslim
The pardoner
Boy/Male
Arabic, Australian
Agent
Boy/Male
Tamil
ShivShekhar | ஷிவ ஷஂகர
Lord Shiva
Girl/Female
Russian
God's gift.
SIDE CHAIN
SIDE CHAIN
SIDE CHAIN
SIDE CHAIN
SIDE CHAIN
n.
One of the halves of the body, of an animals or man, on either side of the mesial plane; or that which pertains to such a half; as, a side of beef; a side of sole leather.
n.
The descent of a mass of earth, rock, or snow down a hill or mountain side; as, a land slide, or a snow slide; also, the track of bare rock left by a land slide.
n.
That which goes wide, or to one side of the mark.
v. i.
To lean on one side.
v. t.
To go or move with one side foremost; to move sidewise; as, to sidle through a crowd or narrow opening.
adv.
So as to be or strike far from, or on one side of, an object or purpose; aside; astray.
a.
Of or pertaining to a side, or the sides; being on the side, or toward the side; lateral.
v. i.
To embrace the opinions of one party, or engage in its interest, in opposition to another party; to take sides; as, to side with the ministerial party.
a.
Growing on one side of a stem; as, one-sided flowers.
n.
Fig.: Aspect or part regarded as contrasted with some other; as, the bright side of poverty.
n.
The right or left part of the wall or trunk of the body; as, a pain in the side.
a.
Having (such or so many) sides; -- used in composition; as, one-sided; many-sided.
superl.
Having considerable distance or extent between the sides; spacious across; much extended in a direction at right angles to that of length; not narrow; broad; as, wide cloth; a wide table; a wide highway; a wide bed; a wide hall or entry.
v. t.
To furnish with a siding; as, to side a house.
a.
Hence, indirect; oblique; collateral; incidental; as, a side issue; a side view or remark.
v. t.
To be or stand at the side of; to be on the side toward.
a.
Having one side only, or one side prominent; hence, limited to one side; partial; unjust; unfair; as, a one-sided view or statement.
n.
Any outer portion of a thing considered apart from, and yet in relation to, the rest; as, the upper side of a sphere; also, any part or position viewed as opposite to or contrasted with another; as, this or that side.
n.
One who takes a side.
imp. & p. p.
of Side