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Protein-coding gene in the species Homo sapiens
Plexin-B1 is a protein of the plexin family that in humans is encoded by the PLXNB1 gene. Within neural tissues, the plexin family serves as transmembrane
Plexin-B1
Protein found in Homo sapiens
induces growth cone collapse in the central nervous system. By binding plexin B1 receptor it functions as an R-Ras GTPase-activating protein (GAP) and
SEMA4D
Protein-coding gene in the species Homo sapiens
Plexin-A1 is a protein that in humans is encoded by the PLXNA1 gene. Plexin A1 has been shown to interact with AKT1. GRCh38: Ensembl release 89: ENSG00000114554
Plexin_A1
Protein-coding gene in the species Homo sapiens
2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"
Rnd1
Protein-coding gene in the species Homo sapiens
2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"
ARHGEF11
Protein-coding gene in the species Homo sapiens
(2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"
PLXNB2
Gutkind, JS; Ahn, N; Guan, KL (2002-09-17). "The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide
Tropic cues involved in growth cone guidance
Tropic_cues_involved_in_growth_cone_guidance
Renewal or physiological repair of damaged nerve tissue
and inhibits remyelination. Sema 4D(Semaphorin 4D) functions through the PlexinB1 receptor and inhibits remyelination. Sema 3A (Semaphorin 3A) is present
Neuroregeneration
Protein-coding gene in the species Homo sapiens
Nirasawa H, Furuyama T, Kogo M, et al. (September 2002). "Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factors". Biochemical
ARHGEF12
Cell type
regulates gonadotropin hormone-releasing hormone-1 neuronal migration through PlexinB1-Met complex". Journal of Cell Biology. 183 (3): 555–66. doi:10.1083/jcb
GnRH_neuron
Protein-coding gene in the species Homo sapiens
PMID 12183458. Swiercz JM, Kuner R, Behrens J, Offermanns S (Jul 2002). "Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone
PLXNB3
Protein-coding gene in the species Homo sapiens
1016/S1534-5807(01)00110-1. PMID 11782313. Vikis HG, Li W, Guan KL (April 2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding"
RACGAP1
Protein-coding gene in the species Homo sapiens
Aurandt J, Vikis HG, Gutkind JS, et al. (2002). "The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide
RAPGEF2
Protein-coding gene in the species Homo sapiens
PMID 11214970. Swiercz JM, Kuner R, Behrens J, Offermanns S (2002). "Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone
SEMA4B
Protein-coding gene in humans
2001. PMC 99857. PMID 11564864. Vikis HG, Li W, Guan KL (2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding"
ARHGEF6
membrane-bound form by MT1-MMP (MMP-14) in tumor cells; it then interacts with plexin B1 on endothelial cells, promoting pro-angiogenic chemotaxis. Shedding of
Proteases_in_angiogenesis
Part of the brain where the optic nerves cross
(Sema6D) expressed at the midline, which form a complex that signals to Nr-CAM/Plexin-A1 receptors on crossing RGC axons. Since all vertebrates, even the earliest
Optic_chiasm
Endocytic pathway found in eukaryotic cells
Acetylcholine receptor 4 EGFR HGFR VEGFR PDGFR NGFR IGFR Tetrameric IL2R PlexinA1 ROBO1 Cholera toxins Shiga toxins Membrane scission is the process by
Fast endophilin-mediated endocytosis
Fast_endophilin-mediated_endocytosis
Protein-coding gene in the species Homo sapiens
Fournier A, Nakamura F, Wang LH, Murakami Y, Kalb RG, et al. (October 1999). "Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors". Cell. 99
Neuropilin_1
Protein receptor active in neurons
documented to regulate neurogenesis and angiogenesis by complexing with Plexin receptors/class-3 semaphorin ligands and Vascular Endothelial Growth Factor
Neuropilin
Type of cell within the eye
RGCs and the midline glia and acts along with Sema6D, mediated via the plexin-A1 receptor. VEGF-A is released from the midline directs RGCs to take a
Retinal_ganglion_cell
Protein-coding gene in humans
Hartwig C, Veske A, Krejcova S, Rosenberger G, Finckh U (August 2005). "Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with
RIT2
Endogenous tag expressed in different cells along neurogenesis and differentiated cells
Ephrin B1; Ephrin B2; GAP-43; HuC; HuD; Internexin alpha; Laminin-1; LINGO-1; MAP1B/MAP5; Mical-3; NAP-22; NGFR; Nestin; Netrin-1; Neuropilin; Plexin-A1;
Neuronal_lineage_marker
Protein family
Blondelle J, Singh MK, Flaherty KM, Means PC, et al. (August 2011). "Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1"
VEGF_receptor
Protein-coding gene in the species Homo sapiens
"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8
MICAL1
Class of compounds
Sema domain (Semaphorin-like), PSI (Plexins, Semaphorins, Integrins), IPT domain (Immunoglobulin-like, Plexins, Transcription factors) and PTK (Protein
C-Met_inhibitor
Protein found in humans
chemoattraction of axon commissural neuron axon guidance regulation of semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse
Glial cell line-derived neurotrophic factor
Glial_cell_line-derived_neurotrophic_factor
Protein-coding gene in humans
regulation of cell migration wound healing, spreading of cells semaphorin-plexin signaling pathway formation of radial glial scaffolds cerebral cortex development
FLNA
Protein-coding gene in the species Homo sapiens
odontogenesis of dentin-containing tooth positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis multicellular
HAND2
Mammalian protein found in Homo sapiens
regulation of autophagy branching morphogenesis of an epithelial tube semaphorin-plexin signaling pathway signal transduction positive regulation of transcription
Hepatocyte growth factor receptor
Hepatocyte_growth_factor_receptor
Protein-coding gene in the species Homo sapiens
Tamagnone L (Oct 2005). "p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling" (PDF). Journal of Cell Science
GRLF1
PLEXIN B1
PLEXIN B1
Girl/Female
Greek
Defender of man.
Girl/Female
Latin American Greek French English Russian
Defender of man.
Female
English
English short form of Latin Alexia, LEXIA means "defender."
Girl/Female
Greek
Defender of man.
Female
English
Unisex contracted form of Latin Alexius, ALEXIS means "defender."
Female
English
Variant spelling of English Lexy, LEXI means "defender of mankind."
Female
English
Elaborated form of English Lexy, LEXINE means "defender of mankind."
Girl/Female
Greek American English
Defender of men, helper. Alexander the Great was a 4th century Macedonian king for whom the...
Girl/Female
American, Finnish, German, Greek, Jamaican
Helper; Defender of Mankind; Noble; Defender
Girl/Female
Australian, Christian, Greek, Hawaiian, Hebrew
Defender of Mankind; Feminine of Alexander
Boy/Male
Greek
Defender of man.
Girl/Female
Latin Greek English
Defender of man.
Male
English
English surname transferred to forename use, derived from the Anglo-Saxon personal name Leofwine, LEWIN means "dear friend."
Female
English
Pet form of Latin Alexia, ALEXINA means "defender."
Boy/Male
Gaelic
Mountain.
Female
English
Variant spelling of English Lexy, LEXIE means "defender of mankind."
Female
English
Feminine form of Latin Alexius, ALEXIA means "defender."
Girl/Female
American, British, Chinese, Christian, English, Finnish, German, Greek, Swedish
Helper; Man's Defender; Helper of Mankind; Defender of Man; Noble Kind
Male
Greek
(ΑλÎξιο) Short form of Greek Alexios, ALEXIO means "defender."
Girl/Female
Latin English Greek
Defender of man.
PLEXIN B1
PLEXIN B1
Boy/Male
Indian
Happiness
Girl/Female
Gujarati, Hindu, Indian, Kannada, Malayalam, Punjabi, Sikh, Tamil
Beautiful Eyes; Home
Boy/Male
Hindu, Indian
One who Rules
Girl/Female
Hindu, Indian
Perfection
Surname or Lastname
English
English : variant of Bowler.German : variant of Boller.Norwegian (Bøler) : habitational name from various farms in southeastern Norway named Bøler, from Old Norse bøli ‘farm’. Compare Bohle.
Girl/Female
Indian
Queen of the apes.
Girl/Female
Indian
Desire
Boy/Male
Hindu
Boy/Male
Biblical
Murmuring.
Boy/Male
Hindu, Indian, Traditional
First Born
PLEXIN B1
PLEXIN B1
PLEXIN B1
PLEXIN B1
PLEXIN B1
v. t.
To lament; to mourn over; as, to plain a loss.
n.
The act of flexing or bending; a turning.
n.
A warrant or assurance.
v.
To make plain or manifest; to explain.
a.
Full See Plein.
n.
The act of flexing or bending; a turning or curving; flexion; hence, obsequious bowing or bending.
a.
Speaking with plain, unreserved sincerity; also, spoken sincerely; as, plain-spoken words.
superl.
Not variegated, dyed, or figured; as, plain muslin.
adv.
In a plain manner; plainly.
superl.
Not luxurious; not highly seasoned; simple; as, plain food.
a.
Consisting of strands twisted together in the ordinary way; as, a plain-laid rope. See Illust. of Cordage.
v. i. & t.
To complain. See Plain.
a.
Level land; usually, an open field or a broad stretch of land with an even surface, or a surface little varied by inequalities; as, the plain of Jordan; the American plains, or prairies.
v.
To plane or level; to make plain or even on the surface.
pl.
of Plexus
a.
Practicing plain dealing; artless. See Plain dealing, under Dealing.
superl.
Without beauty; not handsome; homely; as, a plain woman.
a.
Plan.
superl.
Not much varied by modulations; as, a plain tune.
a.
Full; complete.