Search references for GENE CLUSTER. Phrases containing GENE CLUSTER
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Group of related genes in genomic DNA
A gene cluster is a group of two or more genes found within an organism's DNA that encode similar polypeptides or proteins which collectively share a generalized
Gene_cluster
Group of genes
subsequent divergence, and that a prototypic Hox gene cluster containing at least seven different Hox genes was present in the common ancestor of all bilaterian
Hox_gene
Metabolic gene clusters or biosynthetic gene clusters are tightly linked sets of mostly non-homologous genes participating in a common, discrete metabolic
Metabolic_gene_cluster
is a cluster of genes located on chromosome 11. It is responsible for creating the β-chains found in hemoglobin. This cluster consists of 5 genes: ϵ, Gγ
Human_β-globin_locus
Type B lantibiotic produced by Streptomyces cinnamoneus
cinnamycin is encoded by the cin biosynthetic gene cluster and the synthesis is initiated when the structural gene lanA encodes the precursor peptide which
Cinnamycin
Topics referred to by the same term
Winter cluster, in beekeeping, a well-defined cluster of honey bees in cold temperatures Disease cluster, a grouping of cases of disease Gene cluster, a group
Cluster
Chemical compound
production of Cyclosporin, has the biosynthetic genes arranged into a 12-gene cluster. Of these 12 genes, SimA (Q09164) is the cyclosporin synthetase, SimB
Ciclosporin
Software for understanding biological data
this algorithm has been used both to cluster biosynthetic gene clusters in gene cluster families(GCF) and to cluster said GCFs. Typically, a workflow for
Machine learning in bioinformatics
Machine_learning_in_bioinformatics
Chemical compound
the 9-hydroxy-nonanoic acid portion of mupirocin. The 74 kb mupirocin gene cluster contains six multi-domain enzymes and twenty-six other peptides (Table
Mupirocin
Group of proteins in vertebrates
from their genes because their gene cluster is present between those of class I and class II. The gene cluster was discovered when genes (specifically
MHC_class_III
DNA-containing virus-like particles produced by bacteria and archaea
deleted, and expression of the cluster of structural genes is under the control of cellular regulatory systems. Additional genes that contribute to GTA production
Gene_transfer_agent
Pharmaceutical drug
gene clusters. The function of each of these genes is described by Li and co-workers. A summary of the gene layout and purpose is shown below. Gene layout
Teicoplanin
Drugs to treat parasitic worms and insect pests
prognosis. The gene cluster for biosynthesis of avermectin from S. avermitilis has been sequenced. The avermectin biosynthesis gene cluster encodes enzymes
Avermectin
Red-colored seep of saltwater flowing from Taylor Glacier in Antarctica
analysis indicated the presence of at least four gene clusters involved in secondary metabolism. Two gene clusters are related to the production of aryl polyenes
Blood_Falls
Gene cluster
The ParaHox gene cluster is an array of homeobox genes (involved in morphogenesis, the regulation of patterns of anatomical development) from the Gsx,
ParaHox
Cytokine
human genome, a cluster of thirteen functional IFN genes is located at the 9p21.3 cytoband over approximately 400 kb including coding genes for IFNα (IFNA1
Interferon_type_I
Genetic disorder involving an imprinted genomic region
D, Horsthemke B, Buiting K (2005). "Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader–Willi syndrome". Hum Genet. 116 (3):
Prader–Willi_syndrome
Filamentous fungus
oryzae. While the two fungi share the same cluster of genes that encode for aflatoxin synthesis, this gene cluster is non-functional in A. oryzae. Eiji Ichishima
Aspergillus_oryzae
Molecule used to overcome antibiotic resistance in bacteria
protein and is the first gene found in the clavulanic acid biosynthesis gene cluster, encoded by orf2 of the clavulanic acid gene cluster. The specific mechanism
Clavulanic_acid
Species of bacterium
porphyranase-encoding gene Bp1689 is believed to have been derived from the microbe Zobellia galactanivorans via horizontal gene transfer, as part of a gene cluster containing
Phocaeicola_plebeius
Biological process
Brigitte; Guilhot, Christophe (1999-10-01). "Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis"
Transposon_mutagenesis
Antibiotic
acyltransferase (encoded as OxyA, OxyB, OxyC and OxyP in the oxytetracycline gene cluster) to catalyze the extension of the malonamyl-CoA starting unit with eight
Oxytetracycline
Class of chemical compounds
traditionally designated the "E" gene, whereas precursor peptides are designated gene "A" in most RiPP gene clusters. "A" is a serine protease involved
Ribosomally synthesized and post-translationally modified peptides
Ribosomally_synthesized_and_post-translationally_modified_peptides
Chemical compound
gene cluster via heterologous reconstitution of Blasticidin S production in Streptomyces lividans, indicated that a 20 Kbp gene cluster with 19 genes
Blasticidin_S
similarity networks of biosynthetic gene clusters (BGC). In successive layers of clusterization of biosynthetic gene clusters are used in the automated tool
Computational_genomics
Acetylcholine receptors named for their selective binding of nicotine
demonstrating that their clustering may reflect control of gene expression. CHRNB3 and CHRNA6 are also grouped in a gene cluster, located on 8p11. Multiple
Nicotinic acetylcholine receptor
Nicotinic_acetylcholine_receptor
Antibiotic
NRPS genes from three different sites in the chromosome, using ermEp* for expression of two genes from ectopic loci; other lipopeptide gene clusters, both
Daptomycin
Species of fungus
production of penicillin contain multiple tandem copies of the penicillin gene cluster. Similar to other filamentous fungi, CRISPR/Cas9-mediated genome editing
Penicillium_chrysogenum
Species of bacterium
gene cluster encodes factors for 2,4-DAPG biosynthesis, regulation, export, and degradation. Eight genes, phlHGFACBDE, are annotated in this cluster and
Pseudomonas_fluorescens
Research process
BIG-FAM is a biosynthetic gene cluster family database. DoBISCUIT is a database of secondary metabolite biosynthetic gene clusters. MIBiG (Minimum Information
Genome_mining
Small DNA molecule within a cell
a pre-built database—tools to do this include mge-cluster. As plasmid frequently change their gene content and order, modelling genetic distances between
Plasmid
Protein-coding gene in the species Homo sapiens
instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. GRCh38: Ensembl release 89: ENSG00000274750
HIST1H3E
Chemical compound
H2O2 2 H2O H2O2 2 H2O fosfomycin The complete fosfomycin biosynthetic gene cluster from Streptomyces fradiae has been cloned and sequenced and the heterologous
Fosfomycin
Proteins that bind lipids to transport them in body fluids
members of a multi-gene family that probably evolved from a common ancestral gene. Apo-AI and ApoA4 are part of the APOA1/C3/A4/A5 gene cluster on chromosome
Apolipoprotein
Chemical compound
iminosugar are produced in Bacillus subtilis, a process initiated by a TYB gene cluster composed of gabT1 (aminotransferase), yktc1 (phosphatase), and gutB1
1-Deoxynojirimycin
Pharmaceutical drug
biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase". Gene. 169 (1):
Sirolimus
Shared ancestry between DNA, RNA or protein sequences
methods to construct clusters and determine trees, for example: EnsemblCompara GeneTrees HomoloGene Ortholuge Paralogous genes are genes that are related
Sequence_homology
Class of biochemical compounds
The Bi gene confers bitterness to the entire plant and is genetically associated with an operon-like gene cluster, similar to the gene cluster involved
Cucurbitacin
Antibiotic
ISP5230 (ATCC 17102). Currently the chloramphenicol biosynthetic gene cluster has 17 genes with assigned roles. The synthesis of chloramphenicol can be achieved
Chloramphenicol
Most common genetic condition leading to color blindness
distinct genes, respectively OPN1SW, OPN1MW or OPN1LW. OPN1MW and OPN1LW are located in a gene cluster (along with a locus control region gene) at position
Congenital red–green color blindness
Congenital_red–green_color_blindness
Glycoprotein
Willebrand Factor (PTHR11339). Four of these occur in a well-conserved gene cluster (at 11p15.5 in humans). The EGF-like domain containing mucins. These
Mucin
American bioengineer
identify and correct disease states. Redesign of the nitrogen fixation gene cluster to facilitate its transfer between organisms and control with synthetic
Christopher_Voigt
Polysaccharide gum used as a food additive and thickener
polysaccharide synthesis mechanism of Enterobacteriaceae. Products of the gum gene cluster drive synthesis, polymerization, and export of the repeat unit. "Sicherheitsdatenblatt
Xanthan_gum
Genus of bacteria
of carbohydrate-active enzymes and secondary metabolite biosynthetic gene clusters (siderophores, e-Polylysin and type III lanthipeptides) that are related
Streptomyces
Biomedical text analysis to extract relevant information and knowledge
phylogeny.[citation needed] Methods for determining the association of gene clusters obtained by microarray experiments with the biological context provided
Biomedical_text_mining
East Slavic ethnic group
according to Y chromosome R1a, are included in the general "East European" gene cluster with the rest East and West Slavs (Poles, Czechs and Slovaks), as well
Russians
Gene cluster created by tandem duplications
Tandemly arrayed genes (TAGs) are a gene cluster created by tandem duplications, a process in which one gene is duplicated and the copy is found adjacent
Tandemly_arrayed_genes
Chemical compound
"self-sacrifice" resistance mechanism encoded by the gene calC from the calicheamicin biosynthetic gene cluster. In this study, the scientists revealed calicheamicin
Calicheamicin
Group of open reading frames under the same regulation
is a functioning unit of DNA containing a cluster of genes under the control of a single promoter. The genes are transcribed together into an mRNA strand
Operon
Genes coding for ribosomal RNA
rDNA cluster in the Saccharomycetes such as Saccharomyces cerevisiae. Most eukaryotes however, carry the gene for the 5S rRNA in separate gene repeats
Ribosomal_DNA
Human chromosome
DNA in cells. Chromosome 17 contains the Homeobox B gene cluster. The following are some of the gene count estimates of human chromosome 17. Because researchers
Chromosome_17
Species of fungus
ORFs. Three genes, namely pcbAB, pcbC, and penDE constitute the core sites for penicillin biosynthesis. They are distributed in clusters among other (ORFs)
Penicillium_rubens
Chemical compound
A. fischeri although A.fischeri contains a gene cluster that is homologous to the gliotoxin gene cluster found in the pathogenic A. fumigatus. Gliotoxin
Gliotoxin
Hox gene
Hox cluster containing three genes arose in the early metazoan era. It is suggested that Antennapedia arose from Evx, a non-Hox family of genes. This
Antennapedia
cases, each cluster is made up of sequences produced by a single gene, including alternatively spliced transcripts. However, some genes may be represented
UniGene
Protein-coding gene in the species Homo sapiens
palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. ENSG00000285435
HIST3H3
Species of fungus endemic to New Zealand
toxicity of this species is unknown. It is being investigated to see if its gene cluster that is responsible for blue colouring might be used to manufacture a
Entoloma_hochstetteri
Species of ray-finned fish
fragmented ParaHox cluster, probably because of a whole genome duplication event in their lineage. The presence of an intact ParaHox gene cluster suggests that
Bowfin
Chemical compound
containing a polyketide synthase genomic island (pks) or clb biosynthetic gene cluster. About 20% of humans in high-income countries are colonized with E. coli
Colibactin
DNA pattern affecting anatomy development
arrangement in the genome. Hox genes are typically found in an organized cluster. The linear order of Hox genes within a cluster is directly correlated to
Homeobox
Syndrome caused by chromosomal deletion
Horsthemke, B; Buiting, K (February 2005). "Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome". Human Genetics.
Microdeletion_syndrome
Protein-coding gene in the species Homo sapiens
they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. GRCh38: Ensembl release 89:
Histone_H3.1
Protein family
genes have been defined: the non-clustered Pcdhs which are scattered throughout the genome; and the clustered Pcdhs organized in three gene clusters designated
Protocadherin
Paralytic shellfish toxin
the time of the first proposal. The more recent model describes a STX gene cluster (Sxt) used to obtain a more favorable reaction. The most recent reaction
Saxitoxin
Set of several similar genes
biochemical functions. One such family are the genes for human hemoglobin subunits; the ten genes are in two clusters on different chromosomes, called the α-globin
Gene_family
Naturally occurring glutamate receptor agonist neurotoxin
conversion steps carried out by enzymes encoded within a linked biosynthetic gene cluster. Ibotenic acid is commonly used in research to create site-specific hippocampal
Ibotenic_acid
Segment of DNA that is believed to be a gene
order to define and characterize a biosynthetic gene cluster, all the putative genes within said cluster must first be identified and their functions must
Putative_gene
Moth mainly used in the production of silk
Sekimizu, K. (2017). "In silico identification of lysocin biosynthetic gene cluster from Lysobacter sp. RH2180-5". J. Antibiot. 70 (2): 204–207. doi:10.1038/ja
Bombyx_mori
Species of bacterium
Piepersberg W (1987). "Gene cluster for streptomycin biosynthesis inStreptomyces griseus: Nucleotide sequence of three genes and analysis of transcriptional
Streptomyces_isolates
Process used by obligate anaerobes
of Myxococcota, as they have been found to possess a photosynthesis gene cluster encoding a type-II reaction center with all enzymes and proteins required
Anoxygenic_photosynthesis
Proteins found in maize (corn)
forming a dense gene cluster. The expressed genes in the cluster are interspersed with nonexpressed genes. Some of the expressed genes differ in their
Zein
Protein-coding gene in the species Homo sapiens
dehydrogenase genes. Three genes encoding the closely related alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. The
ADH1B
Blood protein in primates
It is produced from the gene HPR that is located on the long arm of chromosome 16 within the HP (for haptoglobin) gene cluster. Haptoglobin was discovered
Haptoglobin-related_protein
Group of chemical compounds
gene cluster is the largest antibiotic supercluster known so far, with a size of ~210 kb, wherein the PI and PII biosynthetic genes are not clustered
Pristinamycin
Chemical compound
thiopeptide antibiotic which is encoded for and produced by biosynthetic genes clusters in the bacteria Lactobacillus gasseri. Lactocillin was discovered and
Lactocillin
Interbreeding between isolated populations
disease and trait differences have been mapped. Chloroplast capture Gene cluster Gene flow Haplogroup Human genetic variation Hybrid Hybrid vigor Interbreeding
Genetic_admixture
Chemical compound
nosperin (nsp) gene clusters. The swinholide biosynthesis gene cluster is also similar to the tto and lum gene clusters. The swi and mis clusters both include
Swinholide
Protein used in lipid metabolism
susceptibility haplotypes, P2-S2-X1 and P1-S2-X1, discovered in ApoAI-CIII-AIV gene cluster on chromosome 11q23, which confer approximately threefold higher risk
Apolipoprotein_AI
Clade of all animals except sponges and comb jellies
Daniel S.; Degnan, Bernard M. (1996). "The NK Homeobox Gene Cluster Predates the Origin of Hox Genes". Current Biology. 17 (8): 706–710. doi:10.1016/j.cub
ParaHoxozoa
Neuroscientist
27. doi: 10.1007/s00401-019-02066-0. Deming Y, et al. (2019) The MS4A gene cluster is a key regulator of soluble TREM2 and Alzheimer disease risk. Sci Transl
Carlos_Cruchaga
lectin-like receptor subfamily A (KLRA, alternative nomenclature Ly49) is a gene cluster coding proteins from family Ly49, which are membrane receptors expressed
KLRA1
Strain of bacteria
markers: Shiga toxin stx2 positive tellurite resistance gene cluster positive intimin adherence gene negative β-lactamases ampC, ampD, ampE, ampG, ampH are
Escherichia_coli_O104:H4
Protein-coding gene in the species Homo sapiens
instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. GRCh38: Ensembl release 89:
HIST1H2BO
Enzyme found in humans
motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication
FADS2
Chemical compound
using the same gene cluster. The gene cluster encodes completely separate pathways for vidarabine and pentostatin synthesis with no genes shared between
Pentostatin
Paleopolyploidy in early vertebrates
Hox genes in lancelet revealed presence of a single Hox gene cluster, in contrast to the four clusters in humans and mice. Data from additional gene families
2R_hypothesis
Gene cluster
CRT is the gene cluster responsible for the biosynthesis of carotenoids. Those genes are found in eubacteria, in algae and are cryptic in Streptomyces
CRT_(genetics)
Species of endospore forming bacterium
phylogenetic trees do not match because of the ability of the toxin gene cluster to be horizontally transferred. Botulinum neurotoxin (BoNT) production
Clostridium_botulinum
Antibiotic
the identification of and sequence analysis of the tiacumicin B tia-gene cluster. The biosynthesis begins with the formation of the core aglycone, tiacumicinone
Fidaxomicin
Genome browsing and annotation platform
for bacterial secondary metabolism analysis and targeted biosynthetic gene cluster discovery. The IMG-VR system (with the recent updated version IMG/VR
Integrated Microbial Genomes System
Integrated_Microbial_Genomes_System
Genes in the DLX family
two-gene clusters (bigene clusters) with each other. There are DLX1-DLX2, DLX3-DLX4, DLX5-DLX6 clusters in vertebrates, linked to Hox gene clusters HOXD
DLX_gene_family
Ancestor of all current life on Earth
Wächtershäuser, Günter (1998). "Towards a Reconstruction of Ancestral Genomes by Gene Cluster Alignment". Systematic and Applied Microbiology. 21 (4): 473–474, IN1
Last universal common ancestor
Last_universal_common_ancestor
Chemical compound
actinomycin D gene cluster in Streptomyces chrysomallus showed that the four NRPS genes were surrounded on both sides by the two clusters of the genes involved
Dactinomycin
Gene found in various cyanobacteria
KaiB is a gene located in the highly-conserved kaiABC gene cluster of various cyanobacterial species. Along with KaiA and KaiC, KaiB plays a central role
KaiB
Protein
several HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated
HOXD13
Genus of beetles
females Piel, Jörn (2002). "A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles". Proceedings
Paederus
Chemical compound
pathway is largely governed by a single biosynthetic 10-gene cluster. Genes comprising the cluster encode enzymes responsible for nine of the eleven remaining
Noscapine
Protein family around which DNA winds to form nucleosomes
expressed during the whole cell cycle. In mammals, genes encoding canonical histones are typically clustered along chromosomes in 4 different highly-conserved
Histone
Protein-coding gene in the species Homo sapiens
Klasen EC (January 1988). "Apolipoprotein gene cluster on chromosome 19. Definite localization of the APOC2 gene and the polymorphic Hpa I site associated
Apolipoprotein_C-I
Medical condition
alpha-globin gene cluster, causing alpha-thalassemia." ATRX interacts with the transcription co-factor DAXX and the alpha-globin gene cluster. Together they
ATR-X_syndrome
GENE CLUSTER
GENE CLUSTER
Female
English
Pet form of English Eugenia, GENA means "well born."
Girl/Female
French American Greek
Reborn.
Surname or Lastname
Americanized form of German Gehr.English
Americanized form of German Gehr.English : perhaps a variant of Geary 3.Hungarian : from a reduced form of the personal name Gergely, Latin Gregorius (see Gregory).
Female
Yiddish
Variant spelling of Yiddish Heneh, HENE means "favor; grace."
Female
Greek
(ΞÎνη) Feminine form of Greek Xenon, XENE means "foreigner; stranger."
Female
English
Pet form of English Eugenia, GENIE means "well born." This is also a pet form of English Genevieve, probably meaning "race of women."
Surname or Lastname
English and French
English and French : nickname, possibly sometimes applied ironically, from Middle English gente, Old French gent(il) ‘well born’, ‘noble’, ‘courteous’. Compare Gentle.German and English : habitational name for someone from Ghent in Flanders, French name Gand.
Girl/Female
American, Australian, Greek, Hebrew, Scottish
Well Born; The Lord is Gracious; Noble; Similar to Jane
Female
English
English short form of Latin Penelope, PENE means "weaver of cunning."
Girl/Female
Norse
Distinguished.
Male
English
Variant spelling of English Dean, DENE means "dean, ecclesiastical supervisor."
Female
French
French form of Latin Regina, RÉGINE means "queen."
Girl/Female
Biblical
Who reckons or is counted.
Surname or Lastname
English
English : variant spelling of Gain.
Female
German
 Short form of German Helene, possibly LENE means "torch." Compare with another form of Lene.
Girl/Female
English
Combination of Deana (divine) and Dina (from the valley; avenged).
Boy/Male
American, Australian, British, Christian, English, French, German, Greek
Well-born; Noble; Form of Eugene; Born Lucky
Male
English
Short form of English Eugene, GENE means "well born."
Surname or Lastname
English (Cornish)
English (Cornish) : from a short form of the female personal name Jennifer, from Welsh Gwenhwyfar (see Gaynor). Until the 19th century Jennifer was a characteristically Cornish name.German : of uncertain origin; possibly from a Celtic root or from a short form of Heinrich (see Henry) or Johannes (see John).
Boy/Male
Greek American English
Well born.
GENE CLUSTER
GENE CLUSTER
Girl/Female
Tamil
Maulashree | மௌலஷà¯à®°à¯€
Boy/Male
Hebrew
God's justice.
Girl/Female
Greek
Beauty.
Female
Hebrew
(מְ×ִירִית) Variant form of Hebrew Meiri, MEIRIT means "giving light."Â
Male
Italian
Short form of Italian Serafino, FINO means "burning one" or "serpent." Also used as a short form of other names ending with -fino. The feminine form is Fina.
Boy/Male
Australian, Italian
Pure; Conception; Reference to the Immaculate Conception
Boy/Male
Tamil
Pribhakta | பà¯à®°à®¿à®ªà®•à¯à®¤à®¾
Favorite of the devotees, A name of Lord Shiva
Girl/Female
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Oriya, Tamil, Telugu
Unsteady; Lakshmi
Female
Egyptian
, Merte.
Boy/Male
Hindu, Indian
A Part who is Always Winning
GENE CLUSTER
GENE CLUSTER
GENE CLUSTER
GENE CLUSTER
GENE CLUSTER
imp. & p. p.
of Gee
p. p.
Gone.
v. t. & i.
See Gee.
pl.
of Gens
p. p.
Gone.
p. p.
Stepped; gone; advanced.
a.
Past; gone by.
a.
Already past or gone; bygone.
a. & adv.
Past; gone by; since; as, ten years ago; gone long ago.
pl.
of Genu
a.
Already spent; gone by; past.
p. pr. & vb. n.
of Gee
a.
Past; gone by.
n.
Any one of the lene consonants, as p, k, or t (or Gr. /, /, /).
a.
Smooth; as, the lene breathing.
n.
See Genet, a horse.
n.
An African genet (Genetta pardina). See Genet.
a.
Passed away; dead; gone.