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Search references for ESCRT. Phrases containing ESCRT
See searches and references containing ESCRT!ESCRT
Protein pathway in cells
down. The ESCRT system is made up of five separate cytosolic, peripheral membrane protein complexes, known as ESCRT-0, ESCRT-I, ESCRT-II, ESCRT-III and
ESCRT
Protein-coding gene in the species Homo sapiens
VPS37B, ESCRT-I subunit is a protein that in humans is encoded by the VPS37B gene. GRCh38: Ensembl release 89: ENSG00000139722 – Ensembl, May 2017 GRCm38:
VPS37B_subunit_of_ESCRT-I
Membrane-bound extracellular vesicles
required for transport (ESCRT) dependent pathway. ESCRT machinery mediates the ubiquitinated pathway consisting of protein complexes; ESCRT-0, -I, -II, -III
Exosome_(vesicle)
Genus of RNA viruses
pro-inflammatory response and is also known to promote the viral budding process via a ESCRT-dependent pathway. Cell receptor ephrin-B2, which is located on epithelial
Henipavirus
Domain of organisms
Cdv fulfills a similar role. This machinery is related to the eukaryotic ESCRT-III machinery which, while best known for its role in cell sorting, also
Archaea
Intracellular organelle
organelles are proposed to act as platforms for de novo vesiculogenesis via an ESCRT-independent mechanism (Endosomal Sorting Complexes Required for Transport
Hemifusome
American biochemist (born 1959)
membrane remodeling by the Endosomal Sorting Complexes Required for Transport (ESCRT) pathway. Sundquist was born in Saint Paul, Minnesota on September 11, 1959
Wesley_Sundquist
Protein-coding gene in the species Homo sapiens
"Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT function". Traffic. 7 (11): 1551–66
VPS4B
Protein-coding gene in the species Homo sapiens
tumorigenesis and/or progression. The main role of TSG101 is to participate in the ESCRT (endosomal sorting complexes required for transport) pathway. This pathway
TSG101
Biological classification system
required for transport (ESCRT) involved in eukaryotic cell division, known as ESCRT-III, are found in all Thermoproteati groups. The ESCRT-III-like proteins
Two-domain_system
Biological process
nor the FtsZ mechanism. They use a primitive version of the eukaryotic ESCRT-III system (also known as Cdv) to manipulate the membrane into separating
Fission_(biology)
Events leading to cell division
is assembled at the future division site: In archaea that use CdvA, the ESCRT-III polymers CdvA and CdvB assemble at the future division site, then CdvA
Cell_cycle
Vacuole to which materials ingested by endocytosis are delivered
addition of ubiquitin. The endosomal sorting complexes required for transport (ESCRTs) recognise this ubiquitin and sort the protein into the forming lumenal
Endosome
Protein-coding gene in the species Homo sapiens
"Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1".
VPS4A
Nuclear membrane surrounding the nucleus in eukaryotic cells
process dependent on "endosomal sorting complexes required for transport" (ESCRT) made up of cytosolic protein complexes. During nuclear membrane rupture
Nuclear_envelope
Species of virus
reticulum through the endosomal sorting complex required for transport (ESCRT) pathway. This pathway is normally utilized to bud vesicles out of the cell
Hepatitis_C_virus
Physical anomaly involving extra fingers or toes
Anderson, Kathryn V.; Lacy, Elizabeth; Selleri, Licia (October 2014). "ESCRT-II/Vps25 Constrains Digit Number by Endosome-Mediated Selective Modulation
Polydactyly
Network of filamentous proteins that forms the internal framework of cells
tubulin-like (often FtsZ-ring) proteins and sometimes (Thermoproteota) ESCRT-III, which in eukaryotes still has a role in the last step of division.
Cytoskeleton
Species of archaeon
acidocaldarius possess a mechanism of replication homologous to the eukaryotic ESCRT. Sulfolobus acidocaldarius is a facultative autotroph. When growing autotrophically
Sulfolobus_acidocaldarius
Protein-coding gene in humans
S, et al. (2005). "Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo
CHMP4B
Species of virus
Jawed; Gjyshi, Olsi; Bottero, Virginie; Chandran, Bala (April 2016). "ESCRT-0 Component Hrs Promotes Macropinocytosis of Kaposi's Sarcoma-Associated
Kaposi's sarcoma-associated herpesvirus
Kaposi's_sarcoma-associated_herpesvirus
Viral agent that causes mumps
endosomal sorting complex required for transport (ESCRT) structures at the site of budding. There, ESCRT proteins form into concentric spirals and push the
Mumps_virus
Non-profit research institution in Ithaca, New York, U.S.
Molecular Biology. Emr is perhaps best known for his identification of the ESCRT (endosomal sorting complex required for transport) protein machinery. This
Weill Institute for Cell and Molecular Biology
Weill_Institute_for_Cell_and_Molecular_Biology
Protein-coding gene in the species Homo sapiens
is a protein that in humans is encoded by the SNF8 gene. It is a part of ESCRT-II complex. GRCh38: Ensembl release 89: ENSG00000159210 – Ensembl, May 2017
SNF8
furrow ingression. In addition, centralspindlin's interaction with the ESCRT III allows for abscission to occur. Centralspindlin is a heterotetramer
Centralspindlin
Protein family binding to β-galactoside sugars
cellular response to membrane damage are expanding, e.g. Galectin-3 recruits ESCRTs to damaged lysosomes so that lysosomes can be repaired. This occurs before
Galectin
Type of virus that infects the domain of unicellular, prokaryotic organisms or Archaea
complex required for transport (ESCRT) is used by some archaeal viruses, such as STIV and SIRV2, for assembly and exit. ESCRT is used by some eukaryotic viruses
Archaeal_virus
Protein-coding gene in the species Homo sapiens
the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated protein. The two other subunits of ESCRT-I are
VPS28
Protein-coding gene in the species Homo sapiens
along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional
VPS24
Protein family
involves the sequential action of three multiprotein complexes, ESCRT I to III (ESCRT standing for 'endosomal sorting complexes required for transport')
AAA_proteins
Protein-coding gene in humans
membrane extracellular exosome endomembrane system nucleus nuclear matrix ESCRT III complex multivesicular body Biological process carbon catabolite repression
CHMP1A
Protein-coding gene in humans
one of the endosomal sorting complexes required for transport (ESCRT) - specifically ESCRT-III - which are a series of complexes involved in cell membrane
CHMP2B
Kingdom of archaea
signature proteins, including novel GTPases, membrane-remodelling proteins like ESCRT and SNF7, a ubiquitin modifier system, and N-glycosylation pathway homologs
Asgard_archaea
Protein-coding gene in the species Homo sapiens
Enzymatically, it is a lipid scramblase. ATG9A interacts with IQGAP1 and the ESCRT machinery in membrane remodeling. GRCh38: Ensembl release 89: ENSG00000198925
ATG9A
Protein-coding gene in humans
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003
CHMP2A
Protein-coding gene in humans
proteins and a part of endosomal sorting complexes required for transport-III (ESCRT-III) complex. Multivesicular body GRCh38: Ensembl release 89: ENSG00000176108
CHMP6
Protein-coding gene in humans
"The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B". Hum Mol Genet. 14 (1):
CHMP1B
Scottish neurogeneticist and academic
Daniel; Seaman, Matthew N. J.; Hazan, Jamilé; Reid, Evan (2013-08-05). "An ESCRT-spastin interaction promotes fission of recycling tubules from the endosome"
Evan_Reid
American cell biologist
study of the ESCRT (endosomal sorting complexes required for transport) complexes earned him a Shaw Prize in Life Science and Medicine. ESCRTs are required
Scott_D._Emr
Protein-coding gene in humans
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003
CHMP4C
Protein-coding gene in the species Homo sapiens
responsible for the protection against cell death. PDCD6IP protein is part of ESCRT pathway. It participates in the membrane scission of the revers topology
PDCD6IP
Protein found in humans
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–346. doi:10.1016/j.ygeno.2006.04.003
60S_ribosomal_protein_L38
Protein-coding gene in the species Homo sapiens
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–346. doi:10.1016/j.ygeno.2006.04.003
STAMBP
Protein-coding gene in the species Homo sapiens
"Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery". Science. 316 (5833): 1908–12. Bibcode:2007Sci...316.1908C. doi:10
CEP55
Species of protozoan parasite
leader RNA and uses the endosomal sorting complexes required for transport (ESCRT) system to secrete them as extracellular vesicles. When absorbed by other
Trypanosoma_brucei
Earliest stage of infection in the viral life cycle
Pisano, Gina; Veettil, Mohanan Valiya; Chandran, Bala (October 2016). "ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and
Viral_entry
Protein-coding gene in humans
"Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1".
CHMP4A
Protein-coding gene in the species Homo sapiens
It is a member of the endosomal sorting complex required for transport (ESCRT) system. A missense mutation (K382N) in VPS37A protein has been shown to
VPS37A
Protein-coding gene in the species Homo sapiens
membrane plasma membrane endosome late endosome membrane extracellular exosome ESCRT III complex cytosol intracellular anatomical structure late endosome cytoplasmic
RNF103-CHMP3_readthrough
Protein-coding gene in the species Homo sapiens
the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ESCRT (ESCRT-I, -II, -III) complexes orchestrate
VPS25
Final stage of cell division
polymerization of the endosomal sorting complex required for transport III (ESCRT-III), which serves to physically constrict and separate the plasma membrane
Cytokinesis
Regulatory protein found in most eukaryotic tissues
translation, and DNA repair. In cells, lysine 63-linked chains are bound by the ESCRT-0 complex, which prevents their binding to the proteasome. This complex
Ubiquitin
Protein-coding gene in the species Homo sapiens
membrane early endosome extracellular exosome cytoplasm lysosome cytosol ESCRT-0 complex Biological process protein localization to membrane protein targeting
HGS_(gene)
Protein-coding gene in the species Homo sapiens
(March 2011). "Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission". Proceedings of
JADE1
Human chromosome
homolog VEZT: encoding protein Vezatin VPS37B: encoding protein Vps37b, escrt-i subunit YAF2: encoding protein YY1-associated factor 2 ZCCHC8: encoding
Chromosome_12
Protein-coding gene in the species Homo sapiens
mitochondria. MALSU1 was shown to interact with CHMP protein which is part of the ESCRT-III complex (Endosomal Sorting Complex Required for Transport). DUF143 has
MALSU1
Protein-coding gene in humans
multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved
CHMP5
Cellular formation during cytokinesis
T.; Hehnly, H.; Doxsey, S. J. (2012). "Orchestrating vesicle transport, ESCRTs and kinase surveillance during abscission". Nature Reviews. Molecular Cell
Actomyosin_ring
Protein complexes which degrade ubiquitin-tagged proteins by proteolysis
also use the proteasome to control cell cycle, specifically by controlling ESCRT-III-mediated cell division. In plants, signaling by auxins, or phytohormones
Proteasome
Protein-coding gene in the species Homo sapiens
Trambaiolo D, Wakatsuki S, Stenmark H (May 2005). "Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain". J Biol
VPS36
British virologist whose main area of research is HIV/AIDS
cellular protein complex involved in membrane vesicle trafficking, the ESCRT complex. Together with his wife and colleague, Theodora Hatziioannou, they
Paul_Bieniasz
Proteins performing more than one function
metabolism Protease ERK2 H. sapiens MAP kinase Transcriptional repressor ESCRT-II complex D. melanogaster Endosomal protein sorting Bicoid mRNA localization
Protein_moonlighting
American microbiologist
signaling machinery to endosomal sorting complexes required for transport (ESCRT), thus stabilizing viral assembly at the budding site. She continued working
Carol_A._Carter
Science prizes established by Run Run Shaw
Germany 2021 Scott D. Emr United States For the landmark discovery of the ESCRT (Endosomal Sorting Complex Required for Transport) pathway, which is essential
Shaw_Prize
Class of archaea related to eukaryotes
encode numerous eukaryotic signature proteins, including homologues of ESCRT and proteins involved in the ubiquitin modifier system. Among all Asgard
Heimdallarchaeia
Academic journal
Autophagy Cell biology and disease Cilia and flagella Collective cell migration ESCRT machinery Establishing polarity Exploring the nucleus Imaging Invadopodia
Journal_of_Cell_Science
Protein-coding gene in the species Homo sapiens
protein VP40 from Ebola virus. Such infection aids viruses in taking over the ESCRT pathway which is essential for successful budding of the virions from the
NEDD4
Technique for producing oligonucleotides that specifically bind to a target
Fowler KM, Duncan JE, Rosenow M, et al. (May 2020). "ADAPT identifies an ESCRT complex composition that discriminates VCaP from LNCaP prostate cancer cell
Systematic evolution of ligands by exponential enrichment
Systematic_evolution_of_ligands_by_exponential_enrichment
Species of virus
Immature particles are released from the cell with the help of cellular "ESCRT" machinery and then they undergo maturation as the viral protease cleaves
Murine_leukemia_virus
Mexican biologist, researcher and politician (born 1945)
and genes involved in Entamoeba histolytica phagocytosis The role of the ESCRT machinery in amoeba phagocytosis and virulence In 1982 she joined the Department
Esther_Orozco
Swiss biologist
protein, sorting nexins, the adaptor protein complex AP1, components of ESCRTs and associated proteins and the atypical phospholipid LBPA/BMP (see next
Jean_Gruenberg
Catalytically deficient enzymes
Regulation of protein localisation in a cell Tsg101 is a component of the ESCRT-I trafficking complex, and plays a key role in HIV-1 Gag binding and HIV
Pseudoenzyme
binding of the pH sensor Rim21 with ESCRT machinery. Mono-ubiquitination of Rim8 by Rsp5 promotes binding of ESCRT-I subunit Vps23, preventing poly-ubiquitination
Alpha_Arrestin
Protein-coding gene in the species Homo sapiens
vesicular transport and protein sorting, suppresses the degradation of ESCRT proteins signal transducing adaptor molecule 1 and 2". The Journal of Biological
Signal transducing adaptor molecule
Signal_transducing_adaptor_molecule
Protein family
Leser GP, Lamb RA (September 2010). "Influenza virus M2 protein mediates ESCRT-independent membrane scission". Cell. 142 (6): 902–13. doi:10.1016/j.cell
M2_proton_channel
Protein family
the Gag polyprotein. It recruits cellular proteins TSG101 (a component of ESCRT-I) and ALIX to initiate virus particle budding from the plasma membrane
Group-specific_antigen
Protein-coding gene in the species Homo sapiens
rapidly expanding. It has been recently shown that galectin-3 recruits ESCRTs to damaged lysosomes so that lysosomes can be repaired. In early murine
Galectin-3
Protein-coding gene in humans
Luca A, Bucci C (2006). "RILP interacts with the VPS22 component of the ESCRT-II complex". Biochem. Biophys. Res. Commun. 347 (4): 1074–9. doi:10.1016/j
RILP_(gene)
Human protein
ubiquitin 2hth: Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain 2ibi: Covalent Ubiquitin-USP2 Complex 2j7q: CRYSTAL STRUCTURE
Ubiquitin A-52 residue ribosomal protein fusion product 1
Ubiquitin_A-52_residue_ribosomal_protein_fusion_product_1
Protein-coding gene in the species Homo sapiens
ubiquitin 2hth: Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain 2ibi: Covalent Ubiquitin-USP2 Complex 2j7q: CRYSTAL STRUCTURE
Ubiquitin_B
Hypothesis in evolutionary biology
eukaryotic signature proteins. In addition to actin, tubulin, ubiquitin and ESCRT proteins found in TACK archaea, Asgards contain functional genes for several
Eocyte_hypothesis
Protein-coding gene in the species Homo sapiens
ubiquitin 2hth: Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain 2ibi: Covalent Ubiquitin-USP2 Complex 2j7q: CRYSTAL STRUCTURE
40S_ribosomal_protein_S27a
Autophagic pathway mediated by direct engulfment of the cytoplasmic cargo
2008.12.012. PMC 2680079. PMID 19167256. Saksena, S; Emr, SD (Feb 2009). "ESCRTs and human disease". Biochemical Society Transactions. 37 (Pt 1): 167–72
Microautophagy
Protein
reticulum membrane nucleoplasm cytosol endoplasmic reticulum tubular network ESCRT III complex centrosome integral component of membrane Biological process
Spastin
Species of virus
matrix (M) protein in the plasma membrane. Next, budding occurs via the ESCRT complex, and the virion is released at this point in the replication cycle
Bat_mumps_virus
Protein-coding gene in the species Homo sapiens
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003
CTNNBL1
Protein-coding gene in the species Homo sapiens
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003
Exosome_component_9
Plant virus impacting carnation plants
depends on the use of host endosomal sorting complex required for transport (ESCRT). This complex is often used by viruses that need an envelope during infection
Carnation Italian ringspot virus
Carnation_Italian_ringspot_virus
Protein-coding gene in the species Homo sapiens
ontology Molecular function protein binding Cellular component cytoplasm ESCRT-0 complex endosome early endosome membrane intracellular membrane-bounded
STAM2
Protein-coding gene in the species Homo sapiens
atrophin-1 interacting protein 4. This reduces the extent to which the protein ESCRT-0 is ubiquitinated, which reduces its ability to sort CXCR4 into the lysosomes
DTX3L
Protein-coding gene in the species Homo sapiens
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003
Amnionless
Protein family
Field MC, Sali A, Rout MP (June 2011). "Evolution: On a bender--BARs, ESCRTs, COPs, and finally getting your coat". The Journal of Cell Biology. 193
Peridinin-chlorophyll-protein complex
Peridinin-chlorophyll-protein_complex
British-American virologist (1950–2023)
National Academy of Sciences (2008) Influenza virus M2 protein mediates ESCRT-independent membrane scission. Cell (2010) Influenza virus assembly and
Robert_A._Lamb
Protein-coding gene in the species Homo sapiens
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003
ALAS1
Protein-coding gene in the species Homo sapiens
Cellular component cytoplasm cytosol endosome plasma membrane Golgi apparatus ESCRT I complex endosome membrane host cell Biological process protein transport
UBAP1
Protein-coding gene in the species Homo sapiens
Nrg's involvement in regulating dendritic pruning in ddaC neurons in a Rab5/ESCRT-mediated endocytic pathway. Thus, careful regulation of the amount of Neuregulin
Neuregulin_1
Protein-coding gene in the species Homo sapiens
Identifiers Aliases IST1, OLC1, KIAA0174, ESCRT-III associated factor, CHMP8, IST1 factor associated with ESCRT-III External IDs OMIM: 616434; MGI: 1919205;
KIAA0174
Protein-coding gene in the species Homo sapiens
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–46. doi:10.1016/j.ygeno.2006.04.003
SUCLG1
Protein-coding gene in humans
MIT domain-containing proteins bind to multiple components of the human ESCRT III complex". Genomics. 88 (3): 333–346. doi:10.1016/j.ygeno.2006.04.003
CDK13
Genus of viruses
The ribonucleocapsid binds to the matrix protein and buds via the host ESCRT complexes occurs at the plasma membrane host receptors, which mediates endocytosis
Aquaparamyxovirus
ESCRT
ESCRT
ESCRT
ESCRT
Girl/Female
Hindu, Indian, Marathi, Tamil
A Small Song
Girl/Female
Hindu
Girl/Female
Christian, Finnish, French, German, Hungarian, Indian, Latin
Bright
Boy/Male
American, British, English, German
Divine Protector
Boy/Male
American, British, English
Rules by the Spear
Surname or Lastname
English
English : variant spelling of Jordan.North German (mostly Jörden) : probably a variant of Jordan.
Female
English
Variant spelling of English Stormy, STORMIE means "stormy."Â
Boy/Male
Gujarati, Hindu, Indian
Lord Rama
Boy/Male
Muslim
Brave
Girl/Female
Tamil
Swapneeli | ஸà¯à®µà®ªà¯à®¨à®¿à®²
Dream
ESCRT
ESCRT
ESCRT
ESCRT
ESCRT