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Protein-coding gene in the species Homo sapiens
EPH receptor A3 (ephrin type-A receptor 3) is a protein that in humans is encoded by the EPHA3 gene. This gene belongs to the ephrin receptor subfamily
EPH_receptor_A3
Protein-coding gene in humans
EPH receptor A2 (ephrin type-A receptor 2) is a protein that in humans is encoded by the EPHA2 gene. This gene belongs to the ephrin receptor subfamily
EPH_receptor_A2
Protein-coding gene in the species Homo sapiens
EPH receptor A1 (ephrin type-A receptor 1) is a protein that in humans is encoded by the EPHA1 gene. This gene belongs to the ephrin receptor subfamily
EPH_receptor_A1
Protein-coding gene in the species Homo sapiens
EPH receptor A4 (ephrin type-A receptor 4) is a protein that in humans is encoded by the EPHA4 gene. This gene belongs to the ephrin receptor subfamily
EPH_receptor_A4
Protein-coding gene in the species Homo sapiens
the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular
EPH_receptor_B4
Protein family
Eph receptors (Ephs, after erythropoietin-producing human hepatocellular receptors) are a group of receptors that are activated in response to binding
Ephrin_receptor
Protein-coding gene in the species Homo sapiens
protein encoded by this gene is a receptor for ephrin-B family members. EPH receptor B1 has been shown to interact with: ACP1 GRB7 and NCK1 Ephrin-B2 GRCh38:
EPH_receptor_B1
Protein-coding gene in the species Homo sapiens
Alzheimer's disease. A recessive EphB2 gene is responsible for the crested-feather mutation in pigeons. EPH receptor B2 has been shown to interact with:
EPH_receptor_B2
Protein-coding gene in the species Homo sapiens
EPH receptor A5 (ephrin type-A receptor 5) is a protein that in humans is encoded by the EPHA5 gene. This gene belongs to the ephrin receptor subfamily
EPH_receptor_A5
Topics referred to by the same term
Eesti Töörahva Kommuun) Edakkad railway station, in Kerala, India EPH receptor A3, a protein Erythrocyte transketolase, i.e. transketolase found in red
ETK
Modifying synaptic strength via cell adhesion molecules
astrocytes via bi-directional ephrin/EphA signaling. Astrocytes and their processes express ephrin A3, whereas the EphA4 receptor is enriched in hippocampal neurons
Synaptic_stabilization
Protein-coding gene in humans
family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily
EPHA7
Protein-coding gene in the species Homo sapiens
Ephrin A3 is a protein that in humans is encoded by the EFNA3 gene. This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related
Ephrin_A3
Protein-coding gene in the species Homo sapiens
EPH receptor A10 is a protein in humans that is encoded by the EPHA10 gene. Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs)
EPHA10
Protein-coding gene in the species Homo sapiens
a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine
Ephrin_A2
Family of proteins
ligands or Eph family receptor interacting proteins) are a family of proteins that serve as the ligands of the Eph receptor. Eph receptors in turn compose
Ephrin
Protein-coding gene in the species Homo sapiens
family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily
EPHA8
Protein-coding gene in the species Homo sapiens
Ephrin type-A receptor 6 is a protein that in humans is encoded by the EPHA6 gene. EphA6 may serve an important role in breast carcinogenesis and may pose
EPHA6
Class of enzymes
RTK class VI (CCK receptor family) RTK class VII (NGF receptor family) RTK class VIII (HGF receptor family) RTK class IX (Eph receptor family) RTK class
Receptor_tyrosine_kinase
Protein-coding gene in the species Homo sapiens
encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and
Ephrin_A4
Protein-coding gene in the species Homo sapiens
of Medicine. "Entrez Gene: EPHB6 EPH receptor B6". Flanagan JG, Vanderhaeghen P (1998). "The ephrins and Eph receptors in neural development". Annu. Rev
EPHB6
Protein-coding gene in the species Homo sapiens
the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular
EPHB3
Protein found in humans
The encoded protein is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function
Ephrin_B1
Protein family
VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending
VEGF_receptor
Mammalian protein and protein-coding gene
Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation
KIT_gene
short cytoplasmic domain; they interact with their respective receptors Eph-A and Eph-B which are members of the tyrosine kinase family. One unusual
Tropic cues involved in growth cone guidance
Tropic_cues_involved_in_growth_cone_guidance
Protein-coding gene in the species Homo sapiens
its maintenance. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases. EPH receptors typically have a single
Ephrin_B3
Enzyme
factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), stem cell factor receptor, and colony-stimulating factor-1 receptor (Burstein
Tyrosine_kinase
Protein-coding gene in the species Homo sapiens
ephrin ligands that binds to the EphA subclass of Eph receptors. Ephrin A5 has also been shown to bind to the EphB2 receptor. "Reverse" signaling is one unique
Ephrin_A5
Protein-coding gene in the species Homo sapiens
encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and
Ephrin_B2
Family of proteins that bind to fibroblast growth factors
The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of
Fibroblast growth factor receptor
Fibroblast_growth_factor_receptor
Transmembrane protein
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth
Epidermal growth factor receptor
Epidermal_growth_factor_receptor
Protein-coding gene in the species Homo sapiens
encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and
Ephrin_A1
Mammalian protein found in humans
Receptor tyrosine-protein kinase erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated
HER2
Type of membrane receptor that acts through a second messenger
A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic
Metabotropic_receptor
Cell surface receptors
Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF)
Platelet-derived growth factor receptor
Platelet-derived_growth_factor_receptor
Human protein-coding gene
Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded
Platelet-derived growth factor receptor A
Platelet-derived_growth_factor_receptor_A
Family of biomolecules
factors that signal through eph receptors, a class of receptor tyrosine kinases; the family of ephrins include ephrin A1, A2, A3, A4, A5, B1, B2, and B3.[citation
Neurotrophic_factors
Protein domain
BSP-A3; cation-independent mannose-6-phosphate receptor; mannose receptor of macrophages; 180 Kd secretory phospholipase A2 receptor; DEC-205 receptor; 72
Fibronectin_type_II_domain
Protein-coding gene in the species Homo sapiens
domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. KDR
Kinase_insert_domain_receptor
Cell receptor protein found in humans
insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by a hormone
Insulin-like growth factor 1 receptor
Insulin-like_growth_factor_1_receptor
Protein and coding gene in humans
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type
Tropomyosin_receptor_kinase_B
Process of synapse elimination
and the ephrin receptors, Eph, have been found to regulate and direct retinal axon branches. Forward signaling between ephrin-A and EphA, along the anterior-posterior
Synaptic_pruning
Protein found in humans
Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming
Tropomyosin_receptor_kinase_A
Mammalian protein found in Homo sapiens
Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity
Hepatocyte growth factor receptor
Hepatocyte_growth_factor_receptor
Cell-surface receptors which bind angiopoietin
The angiopoietin receptors are receptors that bind angiopoietin. TIE-1 and TIE-2 comprise the cell-surface receptors that bind and are activated by the
Angiopoietin_receptor
Gene involved in the most common form of dwarfism
Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster
Fibroblast growth factor receptor 3
Fibroblast_growth_factor_receptor_3
Protein-coding gene in the species Homo sapiens
Tyrosine-protein kinase receptor UFO is a protein that in human is encoded by the AXL gene. The gene was initially designated as UFO, in allusion to the
AXL_receptor_tyrosine_kinase
shedding for activation. The ephrins EPH receptor A2 and A3 are shed by ADAM10, creating cleaved soluble Eph receptors, which inhibit tumor angiogenesis
Proteases_in_angiogenesis
Chemical compound
epidermal growth factor receptor 2 (HER2; ERBB2), vascular endothelial growth factor receptor (VEGFR), and ephrin B4 (EphB4). The drug activity was
Tesevatinib
American neuroscientist, immunologist, and author
development, his combined gain- and loss-of-function studies of the EphA3, 4, 5, and 6 receptors explored sensory nervous system mapping. These experiments showed
Greg_Lemke
Protein found in humans
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome
Fibroblast growth factor receptor 1
Fibroblast_growth_factor_receptor_1
Protein-coding gene in the species Homo sapiens
Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene
Fibroblast growth factor receptor 2
Fibroblast_growth_factor_receptor_2
Mammalian protein
The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular
RET_proto-oncogene
Protein-coding gene in the species Homo sapiens
types. ODIN is known to regulate the epidermal growth factor receptor (EGFR) and EphA receptor signaling pathways. As a Src family kinase target, ODIN has
ANKS1A
InterPro Family
Trk receptors are a family of tyrosine kinases that regulates synaptic strength and plasticity in the mammalian nervous system. Trk receptors affect neuronal
Trk_receptor
Protein family
RTK class III is a class of receptor tyrosine kinases. It includes PDGFRα, PDGFRβ, C-KIT, CSF1R, and FLT3. Abu-Duhier FM, Goodeve AC, Care RS, et al. (February
RTK_class_III
Protein-coding gene in humans
Platelet-derived growth factor receptor beta is a protein that in humans is encoded by the PDGFRB gene. Mutations in PDGFRB are mainly associated with
PDGFRB
Family of proteins
family of proteins contains four receptor tyrosine kinases, structurally related to the epidermal growth factor receptor (EGFR), its first discovered member
ErbB
Protein found in humans
Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase
Tropomyosin_receptor_kinase_C
Protein found in humans
Receptor tyrosine-protein kinase erbB-3, also known as HER3 (human epidermal growth factor receptor 3), is a membrane bound protein that in humans is
ERBB3
060.500 – receptors, eph family MeSH D12.776.543.750.060.500.050 – receptor, epha1 MeSH D12.776.543.750.060.500.100 – receptor, epha2 MeSH D12.776.543
List of MeSH codes (D12.776.543)
List_of_MeSH_codes_(D12.776.543)
Enzyme and coding gene in humans
Non-receptor tyrosine-protein kinase TYK2 is an enzyme that in humans is encoded by the TYK2 gene. TYK2 was the first member of the JAK family that was
Tyrosine_kinase_2
Protein-coding gene in the species Homo sapiens
Fibroblast growth factor receptor 4 (FGFR-4) is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334 (cluster
Fibroblast growth factor receptor 4
Fibroblast_growth_factor_receptor_4
Protein-coding gene in humans
Macrophage-stimulating protein receptor is a protein that in humans is encoded by the MST1R gene. MST1R is also known as RON (Recepteur d'Origine Nantais)
MST1R
Protein-coding gene in the species Homo sapiens
characterized. Receptor tyrosine-protein kinase erbB-4 is a receptor tyrosine kinase that is a member of the epidermal growth factor receptor family. ERBB4
ERBB4
Protein-coding gene in the species Homo sapiens
family-specific guanine nucleotide exchange factor, is tyrosine phosphorylated via the EphB2/cSrc signaling pathway". Cellular Signalling. 26 (4): 691–696. doi:10.1016/j
PLEKHG2
Protein-coding gene in the species Homo sapiens
positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB". Cell. 111 (2): 251–63. doi:10.1016/S0092-8674(02)01015-2. hdl:20
TCF7
Generating of neurons from neural stem cells in adults
reverse the cognitive deficits in a mouse model of Alzheimer's disease. Eph receptors and ephrin signaling have been shown to regulate adult neurogenesis
Adult_neurogenesis
Protein found in humans
and activation of p53. Once Cdk5 is phosphorylated by a protein called EPH receptor A4, it phosphorylates Guanine nucleotide exchange factors (NGEF) regulating
Cyclin-dependent_kinase_5
850 – receptors, eph family MeSH D08.811.913.696.620.682.725.400.850.050 – receptor, epha1 MeSH D08.811.913.696.620.682.725.400.850.100 – receptor, epha2
List_of_MeSH_codes_(D08)
Transcription factor protein
R, Tensen CP (Aug 2004). "Aberrant expression of the tyrosine kinase receptor EphA4 and the transcription factor twist in Sézary syndrome identified by
Twist-related_protein_1
EPH RECEPTOR-A3
EPH RECEPTOR-A3
EPH RECEPTOR-A3
EPH RECEPTOR-A3
EPH RECEPTOR-A3
EPH RECEPTOR-A3
EPH RECEPTOR-A3
EPH RECEPTOR-A3
EPH RECEPTOR-A3