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Breakdown product of creatine phosphate
Creatinine (/kriˈætɪnɪn, -ˌniːn/; from Ancient Greek κρέας (kréas) 'flesh') is a breakdown product of creatine phosphate from muscle and protein metabolism
Creatinine
Medical laboratory value
urea-to-creatinine ratio (UCR), known in the United States as BUN-to-creatinine ratio, is the ratio of the blood levels of urea (BUN) (mmol/L) and creatinine
Urea-to-creatinine_ratio
Renal function test
through the kidney. The creatinine clearance rate (CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful
Glomerular_filtration_rate
Medical condition
albumin in the sample against its concentration of creatinine is helpful. This is termed the albumin/creatinine ratio (ACR) and microalbuminuria is defined as
Microalbuminuria
Ratio of protein excreted in urine
Urine protein/creatinine ratio is a widely used initial method to estimate daily protein excretion in urine. Since the diagnosis and management of proteinuric
Urine protein/creatinine ratio
Urine_protein/creatinine_ratio
Presence of an excess of serum proteins in the urine
in the urine may be compared to the creatinine level in a spot urine sample. This is termed the protein/creatinine ratio. The 2005 UK Chronic Kidney Disease
Proteinuria
Ways of assessing the function of the kidneys
Bowman's capsule per unit time. Creatinine clearance (CCr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure
Assessment_of_kidney_function
Disease where the kidneys fail to adequately filter waste products from the blood
combination of factors such as decreased urine production or increased serum creatinine. Diagnosis of chronic failure is based on a glomerular filtration rate
Kidney_failure
In enzymology, a creatinine deaminase (EC 3.5.4.21) is an enzyme that catalyzes the chemical reaction creatinine + H2O ⇌ {\displaystyle \rightleftharpoons
Creatinine_deaminase
Colorimetric method used in clinical chemistry
reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. In 1886, Max Jaffe (1841–1911) wrote about
Jaffe_reaction
Protein family
catalyses the hydrolysis of creatinine to creatine, which can then be metabolised to urea and sarcosine by creatinase. creatinine + H2O ⇌ {\displaystyle \rightleftharpoons
Creatininase
Chemical compound
κρέας (kreas). In 1928, creatine was shown to exist in equilibrium with creatinine. Studies in the 1920s showed that consumption of large amounts of creatine
Creatine
Blood test
called urea and electrolytes (U&E or "U and Es"), or urea, electrolytes, creatinine (UEC or EUC or CUE), and are often referred to as 'kidney function tests'
Basic_metabolic_panel
Sudden decrease in kidney function that develops within seven days
function that develops within seven days, as shown by an increase in serum creatinine or a decrease in urine output, or both. Causes of AKI are classified as
Acute_kidney_injury
Breed of cat
concentration of creatinine and symmetric dimethylarginine, but most Birman cats have higher concentrations of creatinine than SDMA. Creatinine is a creatine
Birman
Buildup of metabolic waste due to kidney dysfunction
protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine. Protein toxicity has many causes, including urea cycle disorders, genetic
Protein_toxicity
Excess urea in the blood due to kidney dysfunction
blood of amino acid and protein metabolism end products, such as urea and creatinine, which would normally be excreted in the urine. Uremic syndrome can be
Uremia
Excess of nitrogen-rich compounds in the blood
abnormally high levels of nitrogen-containing compounds (such as urea, creatinine, and other nitrogen-rich compounds) in the blood. It is largely related
Azotemia
Class of enzymes
is often listed in medical literature under incorrect name "creatinine kinase". Creatinine is not a substrate or a product of the enzyme. Reference ranges
Creatine_kinase
Blood test
detect kidney problems. It is not considered as reliable as creatinine or BUN-to-creatinine ratio blood studies. BUN is an indication of kidney health
Blood_urea_nitrogen
Abnormal presence of albumin in the urine
urine (often measured as urine albumin-to-creatinine ratio of >30 milligrams of albumin per 1 gram of creatinine per day). It is a type of proteinuria, and
Albuminuria
Laboratory analysis performed on a blood sample
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels
Blood_test
Abnormal kidney structure or gradual loss of kidney function
derived from the serum creatinine and is proportional to 1/creatinine, i.e., it is a reciprocal relationship; the higher the creatinine, the lower the GFR
Chronic_kidney_disease
Percentage of kidney-filtered sodium excreted in urine
plasma × ( [ creatinine ] urinary × UFR [ creatinine ] plasma ) = 100 × [ Na ] urinary × [ creatinine ] plasma [ Na ] plasma × [ creatinine ] urinary {\displaystyle
Fractional excretion of sodium
Fractional_excretion_of_sodium
Protein used as a biomarker of kidney function
complicated, costly, time-consuming and have potential side-effects. Creatinine is the most widely used biomarker of kidney function. It is inaccurate
Cystatin_C
Liquid by-product of animal metabolism
excess water and metabolic by-products including urea, uric acid, and creatinine. In mammals, urine travels from the kidneys via the ureters to the bladder
Urine
Chemical compound
day through creatine phosphate. Phosphocreatine can be broken down into creatinine, which is then excreted in the urine. A 70 kg man contains around 120
Phosphocreatine
Antibiotic
(hyperkalemia). Can compete with creatinine for secretion into the renal tubule. This can cause an artificial rise in the serum creatinine. Use in EHEC infections
Trimethoprim
Study of the physiology of the kidney
Substances mainly secreted into renal tubule are; H+, K+, NH3, urea, creatinine, histamine and drugs like penicillin. Tubular secretion occurs at Proximal
Renal_physiology
Medical therapy for kidney failure
reached when the glomerular filtration rate is less than 15% of the normal, creatinine clearance is less than 10 mL per minute, and uremia is present. Dialysis
Kidney_dialysis
Change in kidney function during illness
medication through the kidneys. In many cases, it is observed as a measured creatinine clearance above that which is expected given the patient's age, sex, and
Augmented_renal_clearance
clearance of inulin. Creatinine is sometimes used instead of inulin as the reference substance; for example, the calcium-creatinine clearance ratio is used
Renal_clearance_ratio
Natural plant polysaccharides
maintaining a reasonably constant level in the plasma. In the United States, creatinine clearance is more widely used to estimate GFR. A 2017 systematic review
Inulin
Medical study concerned with the kidneys
The serum creatinine concentration is the most important blood test as it is used to estimate the function of the kidney, called the creatinine clearance
Nephrology
Endocrine disease of horses
is currently not recommended for PPID testing. Although corticoid-to-creatinine ratios are generally higher in horses with PPID, numerous false positives
Pituitary pars intermedia dysfunction
Pituitary_pars_intermedia_dysfunction
Chemical compound
been measured in a range of 0–68 micromoles per millimole (μmol/mmol) of creatinine. In the breast milk of healthy lactating women, HMB and L-leucine have
Β-Hydroxy β-methylbutyric acid
Β-Hydroxy_β-methylbutyric_acid
Incurable progressive feline disease
stages based on the creatinine concentration in the blood plasma, which are further subdivided according to the protein-creatinine quotient in the urine
Chronic kidney disease in cats
Chronic_kidney_disease_in_cats
Method of determining chemical concentration
→ colored complex Copper + bathocuproin disulfonate → colored complex Creatinine + picrate → colored complex Iron + bathophenanthroline disulfonate → colored
Colorimetric_analysis
Pharmacokinetic measurement
one another. If applied to creatinine (i.e. creatinine clearance), it follows from the equation that if the serum creatinine doubles the clearance halves
Clearance_(pharmacology)
Smallest type of blood vessel
water, oxygen, carbon dioxide, urea, glucose, uric acid, lactic acid and creatinine. Lymph capillaries connect with larger lymph vessels to drain lymphatic
Capillary
Initial known conditions used for comparison with later data
patient with kidney failure (whose creatinine is usually 3.0 mg/dL) suddenly has a creatinine of 5.0 mg/dL, then his creatinine is out of his normal. For that
Baseline_(science)
Array of tests performed on urine
associated with glomerular hematuria. Proteinuria and elevated blood creatinine alongside hematuria suggests kidney dysfunction. In people at risk, persistent
Urinalysis
Endocrine disorder in cats
non-diabetes related hyperglycaemia. In roughly 10% of hyperthyroid cats serum creatinine levels are increased to the point of azotaemia. In 10-20% of cats increased
Feline_hyperthyroidism
Medication
subunit alpha agonist. The most common adverse reactions include increased creatinine, dysuria, hematuria, urinary frequency, micturition urgency, urinary tract
Nogapendekin_alfa_inbakicept
Protein-coding gene in the species Homo sapiens
mortality. Kidney health is most frequently measured by serum creatinine. Serum creatinine is a marker of kidney function, whereas NGAL is a marker of kidney
Lipocalin-2
Chemical compound
people with creatinine clearance rates equal to or less than 30 mL/minute. A half-life of 22–50 hours has been reported for people with creatinine clearances
Sulfamethoxazole
ACE inhibitor medication
unilateral significant renal artery stenosis (RAS). An early rise in serum creatinine above baseline is expected after initiation of therapy with Ramipril,
Ramipril
Blood test assessing vital organ health
interfere with this test. Serum glucose Calcium Blood urea nitrogen (BUN) Creatinine Electrolyte levels and the balance among them are tightly regulated by
Comprehensive_metabolic_panel
Medical condition
third CCD. Initially diagnosis is typically established by creatine, creatinine, and guanidinoacetate measurement in the plasma, urine, and/or cerebrospinal
Cerebral_creatine_deficiency
Amino acid
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Lysine
Medical condition
degree of pericarditis does not correlate with the degree of serum BUN or creatinine elevation. The pathogenesis is poorly understood. Uremic pericarditis
Uremic_pericarditis
Inflammation of the kidneys
their kidney function through measurements of BUN, creatinine, urinalysis, urine protein/creatinine ratio, and by trending their estimated glomerular filtration
Lupus_nephritis
High blood pressure medication
2016 review. ACE inhibitor can result in an initial increase of serum creatinine, but mostly returns to baseline in a few weeks in majority of patients
Perindopril
Type of kidney disorder
compared to that of small molecules (less than 5 kDa) such as water and creatinine. The syndrome is associated with premature death. SPS has been identified
Shrunken_pore_syndrome
Endogenous GABA precursor
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
N-Acetyl-γ-aminobutyric_acid
Medical test of urine
and microscopic examination Urine creatinine, creatinine clearance — used to assess kidney function Albumin/creatinine ratio — used to diagnose microalbuminuria
Urine_test
Medical condition resulting from overconsumption of bromine (Br)
serum chloride level, electrolytes, glucose, blood urea nitrogen and creatinine, as well as symptoms such as psychosis. Bromine is also radiopaque, so
Bromism
Interruption of cardiac blood supply
Killip class of two or greater), ST-segment deviation, diabetes, serum creatinine, peripheral vascular disease, and elevation of cardiac markers. Myocardial
Myocardial_infarction
Simplest of the alpha-keto acids
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Pyruvic_acid
Antihypertensive medication
other antihypertensive drugs. Severe depression, severe kidney failure (creatinine clearance <15 ml/min), as a precaution in the absence of currently available
Rilmenidine
German biochemist
various compounds and substances, such as cholesterol (Salkowski's test), creatinine, glucose, carbon monoxide, and indole. In 1892 (with Jastrowitz) he was
Ernst_Leopold_Salkowski
Loop diuretic medication
recommended that serum electrolytes (especially potassium), serum CO2, creatinine, BUN levels, and liver and kidney functioning be monitored in patients
Furosemide
Viral pulmonary disease of humans
include thrombocytopenia, leukocytosis, hemoconcentration, elevated serum creatinine levels, hematuria, and proteinuria. Hantavirus-specific IgM and IgG antibodies
Hantavirus_pulmonary_syndrome
Medical condition
high sensitivity amino-terminal B-type natriuretic peptide, creatinine kinase, and creatinine kinase myocardial band, which indicate myocardial damage,
Viral_cardiomyopathy
Chemical compound
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Cysteine_sulfinic_acid
Canine dietary toxicity
ingestion. A blood test may reveal increases in blood urea nitrogen (BUN), creatinine, phosphorus, and calcium. Emesis (induction of vomiting) is the generally
Grape_toxicity_in_dogs
Accumulation of collagen in the skin and internal organs
elevated serum creatinine level is not a contraindication for ACE inhibitors in this population, and slight elevations in creatinine are common during
Systemic_scleroderma
Group of clinically similar illnesses caused by species of hantaviruses
include thrombocytopenia, leukocytosis, hemoconcentration, elevated serum creatinine levels, hematuria, and proteinuria. Hantavirus-specific IgM and IgG antibodies
Hantavirus hemorrhagic fever with renal syndrome
Hantavirus_hemorrhagic_fever_with_renal_syndrome
Medical condition
failure. Patients may present with hyponatremia, hypokalemia, and elevated creatinine. The treatment is supportive until the villous adenoma can be resected
McKittrick–Wheelock_syndrome
Proteinogenic amino acid
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Cysteine
called a basic metabolic panel (blood urea nitrogen, carbon dioxide, creatinine, glucose, serum chloride, serum potassium, serum sodium) CHEM-20 a group
List of medical abbreviations: C
List_of_medical_abbreviations:_C
Chemical compound
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Glutamate-5-semialdehyde
Chemical compound
concentration in urine, creatinine-corrected. Urine concentration is a proxy variable - the measurement is of unmetabolised MOCA - and creatinine-correction affects
4,4'-Methylenebis(2-chloroaniline)
4,4'-Methylenebis(2-chloroaniline)
Endogenous GABA precursor
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
N-Acetylputrescine
Microscopic structural and functional unit of the kidney
phosphate, uric acid, and bicarbonate. Substances secreted include urea, creatinine, potassium, hydrogen, and uric acid. Some of the hormones which signal
Nephron
Species of snake
revealed coagulopathy, thrombocytopenia, and a slight increase in serum creatinine. The patient was treated with Bothropic antivenom and fluid replacement
Bothrops_jararaca
Life-threatening response to infection
coagulation Kidney dysfunction serum creatinine ≥ 2 times the upper limit of normal for age or 2-fold increase in baseline creatinine in people with chronic kidney
Sepsis
Symptoms due to excess consumption of calcium and alkali
test results, such as elevated blood urea nitrogen (BUN) and elevated creatinine, are illustrative of azotemia and kidney impairment. Histologically, the
Milk-alkali_syndrome
Medication used to treat cancer
carboplatin based on renal function. Calvert's formula considers the creatinine clearance and the desired area under curve. After 24 hours, close to 70%
Carboplatin
Angiotensin II receptor antagonist
bilateral renal artery stenosis have been reported to have increases in serum creatinine or blood urea nitrogen. There has been no long-term use of olmesartan
Olmesartan
Warm-blooded animals with wings and feathers
nitrogenous wastes as ammonia. They also excrete creatine, rather than creatinine like mammals. This material, as well as the output of the intestines,
Bird
Chemical compound
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
L-Arginine_L-pyroglutamate
Cancer of plasma cells
>2.75 mmol/L (>11 mg/dL) Renal insufficiency: creatinine clearance <40 mL per minute or serum creatinine >1.77 mol/L (>2 mg/dL) Anemia: hemoglobin value
Multiple_myeloma
Chemotherapy and immunosuppressant medication
complete blood count, liver function tests, and creatinine are recommended. Measurements of creatinine are recommended at least every two months. Folic
Methotrexate
Qualitative chemical test, primarily used for detecting cholesterol
different kinds of molecules (besides cholesterol and other sterols also for creatinine, carbon monoxide, glucose and indoles). A solution that has tested positive
Salkowski's_test
Chemical compound
warns against a mean rise in serum creatinine of 0.11 mg/dL due to inhibition of tubular secretion of creatinine and does not affect GFR. In 2019 there
Dolutegravir
Medical condition
exposure indices for blood and urine cadmium levels are 5 μg/L and 5 μg/g creatinine, respectively, in random specimens. Persons who have sustained kidney
Cadmium_poisoning
Medical diagnostic method
Alternatively, the urine sodium can be standardized to the excretion of creatinine using a formula such as the fractional excretion of sodium (FENa). Because
Urine_sodium
Diuretics that act along the loop of Henle in the kidneys
can only replace thiazide-type diuretics if there is renal impairment (Creatinine of more than 1.5 mg/dL or estimated glomerular filtration rate (eGFR)
Loop_diuretic
Percentages of fat, bone, water and muscle in human bodies
circumference (MAMC), and creatinine height ratio (CHI). Creatinine height ratio is calculated as 24-hour urine creatinine multiplied by 100 over the
Body_composition
Medical condition
including histochemical staining of renal biopsy specimens, the measure of creatinine level, GFR level, and urine output, urine microscopy, CT scanning, and
Phosphate_nephropathy
Medical condition
pulse oximetry, testing serum electrolyte, blood urea nitrogen (BUN), and creatinine levels, measuring arterial blood gases, chest radiography, electrocardiogram
Chlorine_gas_poisoning
Failure of the heart to provide sufficient blood flow
strongest risk factor for heart failure. Diabetic women with depressed creatinine clearance or elevated BMI were at the highest risk of heart failure. While
Heart_failure
Chemical compound
effects include decreased hemoglobin, anemia, hypoxia, fatigue, increased creatinine, headache, dizziness, increased glucose, and nausea. Belzutifan was approved
Belzutifan
Chemical compound
of relaxin are also seen in the kidneys, by significantly increasing creatinine clearance, which is a measure of kidney function, as well as increased
Serelaxin
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Cysteine_metabolism
Pharmaceutical drug
levels), surgical wound complication, weight increase, increased serum creatinine (a marker of kidney problems), hypophosphataemia (low blood phosphate
Basiliximab
Chemical compound
decreased neutrophils, increased alanine aminotransferase (ALT), increased creatinine, increased alkaline phosphatase, fatigue, constipation, musculoskeletal
Pralsetinib
Medical condition
ovary, ascites, hematocrit > 45%, WBC > 15,000, oliguria, creatinine 1.0–1.5 mg/dl, creatinine clearance > 50 ml/min, liver dysfunction, and anasarca. Critical
Ovarian hyperstimulation syndrome
Ovarian_hyperstimulation_syndrome
Organic compound
3-Phosphoglyceric acid glycine→creatine: Glycocyamine Phosphocreatine Creatinine G→glutamate→ α-ketoglutarate histidine→ Urocanic acid Imidazole propionate
Fumaric_acid
CREATININE
CREATININE
CREATININE
CREATININE
Male
Hungarian
Hungarian form of German Karl, KÃROLY means "man."
Boy/Male
African, Danish, German, Swedish
Oak Tree
Girl/Female
Australian
Youthful Like a Flower
Girl/Female
Hindu
Girl/Female
Hindu, Indian, Tamil
A River
Boy/Male
Indian
Amazing
Girl/Female
Hindu
Girl/Female
Irish Italian Greek Swedish
Kind.
Girl/Female
Arabic, Muslim
Sky; Heaven
Boy/Male
Muslim
A narrator of Hadith had this name
CREATININE
CREATININE
CREATININE
CREATININE
CREATININE