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URM1

  • URM1

    • Protein family

    Ubiquitin-related modifier-1 (URM1) is a ubiquitin-like protein that modifies proteins in the yeast ubiquitin-like urmylation pathway. Structural comparisons

    URM1

    URM1

    URM1

  • Signal peptide

    • Short peptide present at N-terminal of newly synthesized proteins

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Signal peptide

    Signal_peptide

  • Protein folding

    • Change of a linear protein chain to a 3D structure

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Protein folding

    Protein folding

    Protein_folding

  • Post-translational modification

    • Chemical changes in proteins following their translation from mRNA

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Post-translational modification

    Post-translational modification

    Post-translational_modification

  • Chaperone (protein)

    • Proteins assisting in protein folding

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Chaperone (protein)

    Chaperone (protein)

    Chaperone_(protein)

  • Heat shock protein

    • Family of proteins

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Heat shock protein

    Heat_shock_protein

  • Ubiquitin

    • Regulatory protein found in most eukaryotic tissues

    known as interferon-stimulated gene-15 ISG15), ubiquitin-related modifier-1 (URM1), neuronal-precursor-cell-expressed developmentally downregulated protein-8

    Ubiquitin

    Ubiquitin

    Ubiquitin

  • SUMO protein

    • Family of proteins which attach to other proteins to modify them

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    SUMO protein

    SUMO protein

    SUMO_protein

  • Survival of motor neuron

    • Protein in animal cells

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Survival of motor neuron

    Survival of motor neuron

    Survival_of_motor_neuron

  • Hsp90

    • Heat shock proteins with a molecular mass around 90kDa

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Hsp90

    Hsp90

    Hsp90

  • Ubiquitin-like protein

    • Family of small proteins

    are known to covalently modify other proteins: SUMO, NEDD8, ATG8, ATG12, URM1, UFM1, FAT10, and ISG15. One additional protein, known as FUBI, is encoded

    Ubiquitin-like protein

    Ubiquitin-like protein

    Ubiquitin-like_protein

  • Succinylation

    • Addition of a succinyl group to a lysine group of a protein

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Succinylation

    Succinylation

  • Two-domain system

    • Biological classification system

    from multiple genomes of Aigarchaeota. Ubiquitin-related protein called Urm1 is also present in Crenarchaeota. DNA replication system (GINS proteins)

    Two-domain system

    Two-domain system

    Two-domain_system

  • Ubiquitin ligase

    • Protein

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Ubiquitin ligase

    Ubiquitin ligase

    Ubiquitin_ligase

  • Protein targeting

    • Biological mechanism for routing proteins

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Protein targeting

    Protein_targeting

  • GroES

    • Protein

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    GroES

    GroES

    GroES

  • Cullin

    • Hydrophobic scaffold protein

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Cullin

    Cullin

    Cullin

  • Hsp70

    • Family of heat shock proteins

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Hsp70

    Hsp70

    Hsp70

  • Target peptide

    • Type of peptide chain

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Target peptide

    Target_peptide

  • HSPA1A

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA1A

    HSPA1A

    HSPA1A

  • DNAJB9

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJB9

    DNAJB9

    DNAJB9

  • Ubiquitin-activating enzyme

    • Class of enzymes

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Ubiquitin-activating enzyme

    Ubiquitin-activating enzyme

    Ubiquitin-activating_enzyme

  • UBE2C

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2C

    UBE2C

    UBE2C

  • ISG15

    • Protein found in humans

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    ISG15

    ISG15

    ISG15

  • DNAJC10

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJC10

    DNAJC10

    DNAJC10

  • Ubiquitin-conjugating enzyme

    • Protein family

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Ubiquitin-conjugating enzyme

    Ubiquitin-conjugating_enzyme

  • SMN1

    • Protein-coding gene in humans

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    SMN1

    SMN1

    SMN1

  • Chaperonin

    • Family of heat shock proteins

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Chaperonin

    Chaperonin

    Chaperonin

  • Lysine malonylation

    • Post-translational modification

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Lysine malonylation

    Lysine malonylation

    Lysine_malonylation

  • UBA1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBA1

    UBA1

    UBA1

  • Neddylation

    • Post-translational modifications involving the protein NEDD8

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Neddylation

    Neddylation

    Neddylation

  • Deubiquitinating enzyme

    • Protein family

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Deubiquitinating enzyme

    Deubiquitinating enzyme

    Deubiquitinating_enzyme

  • DNAJC19

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJC19

    DNAJC19

    DNAJC19

  • CBL (gene)

    • Mammalian gene

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    CBL (gene)

    CBL (gene)

    CBL_(gene)

  • Ubiquitin-protein ligase E3B

    • Protein-coding gene in Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Ubiquitin-protein ligase E3B

    Ubiquitin-protein ligase E3B

    Ubiquitin-protein_ligase_E3B

  • Von Hippel–Lindau tumor suppressor

    • Mammalian protein found in humans

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Von Hippel–Lindau tumor suppressor

    Von Hippel–Lindau tumor suppressor

    Von_Hippel–Lindau_tumor_suppressor

  • HSPA8

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA8

    HSPA8

    HSPA8

  • ATG8

    • Protein in budding yeast

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    ATG8

    ATG8

    ATG8

  • Mdm2

    • Protein-coding gene in humans

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Mdm2

    Mdm2

    Mdm2

  • CTU2

    • Protein-coding gene in the species Homo sapiens

    "A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway". Proc. Natl. Acad. Sci. U.S.A. 105 (47):

    CTU2

    CTU2

    CTU2

  • Clusterin

    • Protein found in humans

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Clusterin

    Clusterin

    Clusterin

  • UBE2O

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2O

    UBE2O

    UBE2O

  • Molybdopterin synthase

    • Specifically, the small subunit MoaD in prokaryotes is a sequence homolog of Urm1, indicating that MPT synthase probably shares a common ancestor with ubiquitin

    Molybdopterin synthase

    Molybdopterin_synthase

  • Prokaryotic ubiquitin-like protein

    • Protein family

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Prokaryotic ubiquitin-like protein

    Prokaryotic ubiquitin-like protein

    Prokaryotic_ubiquitin-like_protein

  • SMN2

    • Protein-coding gene in humans

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    SMN2

    SMN2

    SMN2

  • TRAP1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    TRAP1

    TRAP1

    TRAP1

  • UBR1

    • Mammalian protein found in Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBR1

    UBR1

    UBR1

  • Hsp27

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Hsp27

    Hsp27

    Hsp27

  • UBE2I

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2I

    UBE2I

    UBE2I

  • HSPA4

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA4

    HSPA4

    HSPA4

  • Heat shock protein 47

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Heat shock protein 47

    Heat shock protein 47

    Heat_shock_protein_47

  • USP6

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    USP6

    USP6

    USP6

  • ATG12

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    ATG12

    ATG12

    ATG12

  • List of human protein-coding genes 8

    • Q14146 17942 URGCP HGNC:30890; Q8TCY9 17943 URI1 HGNC:13236; O94763 17944 URM1 HGNC:28378; Q9BTM9 17945 UROC1 HGNC:26444; Q96N76 17946 UROD HGNC:12591;

    List of human protein-coding genes 8

    List_of_human_protein-coding_genes_8

  • UBE2G2

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2G2

    UBE2G2

    UBE2G2

  • HSPA12A

    • Human gene

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA12A

    HSPA12A

  • UBE2L6

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2L6

    UBE2L6

    UBE2L6

  • HSP90B1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSP90B1

    HSP90B1

    HSP90B1

  • HSPA6

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA6

    HSPA6

    HSPA6

  • UBE2D3

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2D3

    UBE2D3

    UBE2D3

  • Ataxin 3

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Ataxin 3

    Ataxin 3

    Ataxin_3

  • UBE2D2

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2D2

    UBE2D2

    UBE2D2

  • Auxilin

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Auxilin

    Auxilin

    Auxilin

  • CYLD (gene)

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    CYLD (gene)

    CYLD (gene)

    CYLD_(gene)

  • UBE2M

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2M

    UBE2M

    UBE2M

  • DNAJB1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJB1

    DNAJB1

    DNAJB1

  • DNAJC5

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJC5

    DNAJC5

    DNAJC5

  • GroEL

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    GroEL

    GroEL

    GroEL

  • HSPA4L

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA4L

    HSPA4L

    HSPA4L

  • UBE2A

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2A

    UBE2A

    UBE2A

  • DNAJB6

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJB6

    DNAJB6

    DNAJB6

  • DNAJC3

    • Human protein and coding gene

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJC3

    DNAJC3

    DNAJC3

  • UBE2B

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2B

    UBE2B

    UBE2B

  • Binding immunoglobulin protein

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Binding immunoglobulin protein

    Binding immunoglobulin protein

    Binding_immunoglobulin_protein

  • DNAJA2

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJA2

    DNAJA2

    DNAJA2

  • HSP90AB1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSP90AB1

    HSP90AB1

    HSP90AB1

  • DNAJB4

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJB4

    DNAJB4

    DNAJB4

  • UFM1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UFM1

    UFM1

    UFM1

  • MOCS3

    • Protein-coding gene in the species Homo sapiens

    activity molybdopterin-synthase sulfurtransferase activity metal ion binding URM1 activating enzyme activity protein binding catalytic activity ubiquitin-like

    MOCS3

    MOCS3

    MOCS3

  • HSPA9

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA9

    HSPA9

    HSPA9

  • UBE2L3

    • Protein-coding gene in humans

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2L3

    UBE2L3

    UBE2L3

  • HSPA2

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA2

    HSPA2

    HSPA2

  • HSPA1B

    • Human gene

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA1B

    HSPA1B

    HSPA1B

  • FANCL

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    FANCL

    FANCL

    FANCL

  • UBE2V2

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2V2

    UBE2V2

    UBE2V2

  • DNAJA3

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJA3

    DNAJA3

    DNAJA3

  • Heat shock protein 90kDa alpha (cytosolic), member A1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Heat shock protein 90kDa alpha (cytosolic), member A1

    Heat shock protein 90kDa alpha (cytosolic), member A1

    Heat_shock_protein_90kDa_alpha_(cytosolic),_member_A1

  • UBE2G1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2G1

    UBE2G1

    UBE2G1

  • UBE2N

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2N

    UBE2N

    UBE2N

  • HSPA1L

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    HSPA1L

    HSPA1L

    HSPA1L

  • DNAJB11

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJB11

    DNAJB11

    DNAJB11

  • Hsp33

    • InterPro Family

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    Hsp33

    Hsp33

  • UBE2D1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2D1

    UBE2D1

    UBE2D1

  • DNAJC1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJC1

    DNAJC1

    DNAJC1

  • BIRC6

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    BIRC6

    BIRC6

    BIRC6

  • DNAJA1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJA1

    DNAJA1

    DNAJA1

  • UBE2V1

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2V1

    UBE2V1

    UBE2V1

  • CDC34

    • Protein-coding gene in humans

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    CDC34

    CDC34

    CDC34

  • UBE2H

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    UBE2H

    UBE2H

    UBE2H

  • DNAJC14

    • Protein-coding gene in the species Homo sapiens

    SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12 FUB1 MUB UBL5 Prokaryotic ubiquitin-like

    DNAJC14

    DNAJC14

    DNAJC14

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