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TRPM3

  • TRPM3
  • Protein-coding gene in the species Homo sapiens

    channel subfamily M member 3 is a protein that in humans is encoded by the TRPM3 gene. The product of this gene belongs to the family of transient receptor

    TRPM3

    TRPM3

    TRPM3

  • TRPM3-related neurodevelopmental disorder
  • Rare disease

    TRPM3-related neurodevelopmental disorder is a monogenetic developmental and epileptic encephalopathy that affects the central nervous system. The broad

    TRPM3-related neurodevelopmental disorder

    TRPM3-related_neurodevelopmental_disorder

  • TRPM
  • Family of transport proteins

    widely among TRPM channels. TRPM4 and TRPM5 are impermeable to calcium. TRPM3, TRPM6 and TRPM7 are highly permeable to both calcium and magnesium. The

    TRPM

    TRPM

  • CIM-0216
  • Chemical compound

    selective activator of the TRPM3 calcium channel. It produces nociception and inflammation and is used to study the function of the TRPM3 receptor in these processes

    CIM-0216

    CIM-0216

    CIM-0216

  • Primidone
  • Barbiturate medication used to treat seizures and tremors

    inhibit the TRPM3 ion channel; whether this effect contributes to its anticonvulsant effect is not known, but gain-of-function mutations in TRPM3 were shown

    Primidone

    Primidone

    Primidone

  • Special interest (autism)
  • Highly focused interests most common in autistic people

    SYNGAP1-related intellectual disability Tatton-Brown–Rahman syndrome Timothy syndrome TRPM3-related neurodevelopmental disorder Tuberous sclerosis Williams syndrome

    Special interest (autism)

    Special interest (autism)

    Special_interest_(autism)

  • Hesperetin
  • Chemical compound

    to develop drugs against cardiac arrhythmias. Hesperetin also inhibits TRPM3 channels in vitro. "Flavonoids". Micronutrient Information Center, Linus

    Hesperetin

    Hesperetin

    Hesperetin

  • Ononetin
  • Chemical compound

    potential ion channel TRPM3 and has analgesic effects in animal studies, as well as being used for research into the role of TRPM3 in the immune system

    Ononetin

    Ononetin

    Ononetin

  • Thermoreceptor
  • Receptive portion of a sensory neuron

    Channels shown: TRPA1, TRPM8, TRPV4, TRPV3, TRPV1, TRPM3, ANO1, TRPV2

    Thermoreceptor

    Thermoreceptor

    Thermoreceptor

  • Pregnenolone
  • Chemical compound

    sulfate has been shown to activate the transient receptor potential M3 (TRPM3) ion channel in hepatocytes and pancreatic islets causing calcium entry

    Pregnenolone

    Pregnenolone

    Pregnenolone

  • Transient receptor potential channel
  • Class of transport proteins

    into two major clades, αTRPM and βTRPM. αTRPMs include vertebrate TRPM1, TRPM3, and the "chanzymes" TRPM6 and TRPM7, as well as the only insect TRPM channel

    Transient receptor potential channel

    Transient_receptor_potential_channel

  • Infodumping
  • Excessive information sharing

    SYNGAP1-related intellectual disability Tatton-Brown–Rahman syndrome Timothy syndrome TRPM3-related neurodevelopmental disorder Tuberous sclerosis Williams syndrome

    Infodumping

    Infodumping

  • Isosakuranetin
  • Chemical compound

    orange, blood orange and mandarin. Isosakuranetin is a potent inhibitor of TRPM3 channels. In soybean, isosakuranetin is biosynthesised from naringenin in

    Isosakuranetin

    Isosakuranetin

    Isosakuranetin

  • Pregnenolone sulfate
  • Chemical compound

    agonist of the sigma receptor, as well as an activator of the TRPM1 and TRPM3 channels. It may also interact with potassium channels and voltage-gated

    Pregnenolone sulfate

    Pregnenolone sulfate

    Pregnenolone_sulfate

  • Lipopolysaccharide
  • Class of molecules found in the outer membrane of Gram-negative bacteria

    other members of the sensory TRP channel family as well, such as TRPV1, TRPM3 and to some extent TRPM8. LPS is recognized by TRPV4 on epithelial cells

    Lipopolysaccharide

    Lipopolysaccharide

    Lipopolysaccharide

  • Thermoception
  • Sensation and perception of temperature

    Channels shown: TRPA1, TRPM8, TRPV4, TRPV3, TRPV1, TRPM3, ANO1, TRPV2

    Thermoception

    Thermoception

  • Neurodevelopmental disorder
  • Set of disorders affecting development of nervous system

    Epigenetics Microcephaly SCN2A-Related Disorders (epilepsy and autism) Teratology TRPM3-related neurodevelopmental disorder Channelopathies "What Are Neurodevelopmental

    Neurodevelopmental disorder

    Neurodevelopmental_disorder

  • Epipregnanolone
  • Chemical compound

    allosteric modulator of the NMDA and GABAA receptors and also acts as a TRPM3 channel activator. Isopregnanolone 3β-Dihydroprogesterone Pregnanolone

    Epipregnanolone

    Epipregnanolone

    Epipregnanolone

  • List of neurosteroids
  • NMDA receptor positive allosteric modulator, sigma-1 receptor agonist, TRPM3 agonist, other actions The following are proneurosteroids: Pregnenolone

    List of neurosteroids

    List of neurosteroids

    List_of_neurosteroids

  • Late talker
  • Toddler with delayed language development

    SYNGAP1-related intellectual disability Tatton-Brown–Rahman syndrome Timothy syndrome TRPM3-related neurodevelopmental disorder Tuberous sclerosis Williams syndrome

    Late talker

    Late_talker

  • S100A1
  • Protein-coding gene in the species Homo sapiens

    treating advanced heart failure. S100 interacts with PGM1 S100B S100A4 TRPM3 Titin RYR2 SERCA2A PLB RYR1 GRCh38: Ensembl release 89: ENSG00000160678

    S100A1

    S100A1

    S100A1

  • Cation channel superfamily
  • Family of ion channel proteins

    gated ion channels. TRPC1; TRPC3; TRPC4; TRPC5; TRPC6; TRPC7 TRPM1; TRPM2; TRPM3; TRPM4; TRPM5; TRPM6; TRPM7; TRPM8 TRPV1; TRPV2; TRPV3; TRPV4; TRPV5; TRPV6

    Cation channel superfamily

    Cation channel superfamily

    Cation_channel_superfamily

  • List of human protein-coding genes 8
  • Q9HCX4 17479 TRPM1 HGNC:7146; Q7Z4N2 17480 TRPM2 HGNC:12339; O94759 17481 TRPM3 HGNC:17992; Q9HCF6 17482 TRPM4 HGNC:17993; Q8TD43 17483 TRPM5 HGNC:14323;

    List of human protein-coding genes 8

    List_of_human_protein-coding_genes_8

  • List of investigational headache and migraine drugs
  • Investigational antimigraine drugs

    BHV-2100 – transient receptor potential cation channel subfamily M member 3 (TRPM3) antagonist – migraine [8] Botulinum toxin A longer acting (IPN-10200; mrBoNT)

    List of investigational headache and migraine drugs

    List_of_investigational_headache_and_migraine_drugs

  • Index of biophysics articles
  • Index of articles on biophysics

    (channel) TRPC TRPC1 TRPC2 TRPC3 TRPC4AP TRPC5 TRPC6 TRPC7 TRPM TRPM1 TRPM2 TRPM3 TRPM4 TRPM5 TRPM6 TRPM7 TRPM8 TRPML TRPN TRPP TRPP3 TRPV TRPV1 TRPV2 TRPV3

    Index of biophysics articles

    Index_of_biophysics_articles

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