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TRONTINEMAB

• Trontinemab

Monoclonal antibody

Trontinemab (RG6102) is a monoclonal antibody (mAb) developed by Roche/Genentech for the treatment of Alzheimer's disease. It is based on gantenerumab

Trontinemab

Trontinemab

• Brainshuttle

Technology assisting antibody uptake

It has been tested with anti-amyloid monoclonal antibodies such as trontinemab. The formulation reported in a 2013 paper by Niewoehner et al. used a

Brainshuttle

Brainshuttle

• Gantenerumab

Monoclonal antibody protein

Gantenerumab has been further developed into trontinemab, which started a Phase III trial in 2025. Trontinemab consists of gantenerumab fused to Roche's

Gantenerumab



Gantenerumab

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TRONTINEMAB