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TNP2

TNP2

Protein-coding gene in the species Homo sapiens

Nuclear transition protein 2 is a protein that in humans is encoded by the TNP2 gene. GRCh38: Ensembl release 89: ENSG00000178279 – Ensembl, May 2017 GRCm38:

TNP2

Protamine

Protein family

protamines are denoted PRM1 and PRM2. In mice and humans, PRM1, PRM2, and TNP2 are co-located in a conserved gene cluster. Eutherian mammals generally have

Protamine

Chromosome abnormality

Abnormal number or structure of chromosomes

normally help organize DNA, are replaced with transition proteins (TNP1, TNP2) and then protamines (PRM1, PRM2). While this packaging protects the DNA

Chromosome abnormality

Chromosome_abnormality

Perinucleolar compartment

NCAPH NCAPH2 SMC2 SMC4 DNA repair SMC5 SMC6 Transition nuclear protein: TNP1 TNP2 Nuclear matrix (Nucleoskeleton) Nucleoplasm (Nucleosol) LITAF see also transcription

Perinucleolar compartment

Perinucleolar_compartment

List of human protein-coding genes 8

P45379 17172 TNNT3 HGNC:11950; P45378 17173 TNP1 HGNC:11951; P09430 17174 TNP2 HGNC:11952; Q05952 17175 TNPO1 HGNC:6401; Q92973 17176 TNPO2 HGNC:19998;

List of human protein-coding genes 8

List_of_human_protein-coding_genes_8

Transition nuclear protein

Proteins that are involved in the packaging of sperm nuclear DNA during spermiogenesis

subsequently themselves replaced by protamines. TNPs in humans include TNP1 and TNP2. Chromatin Histone Protamine Sperm Spermatogenesis Spermiogenesis Meistrich

Transition nuclear protein

Transition_nuclear_protein

TNP1

Protein-coding gene in the species Homo sapiens

"Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations". J. Androl. 26 (6):

TNP1