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Chemical compound
Taxadiene (taxa-4,11-diene) is a diterpene. Taxadiene is the first committed intermediate in the synthesis of taxol. Six hydroxylation reactions, and
Taxadiene
Organic compound
important compounds such as retinol, phytol or taxadiene. Taxanes are class of diterpenoids featuring a taxadiene core. They are produced by plants of the genus
Diterpene
The enzyme taxadiene synthase (EC 4.2.3.17) catalyzes the chemical reaction geranylgeranyl diphosphate ⇌ {\displaystyle \rightleftharpoons } taxa-4,11-diene
Taxadiene_synthase
Medication used for cancer
intermediate known as taxadiene. Taxadiene then undergoes a series of 10 oxidations via NADPH, forming the intermediate taxadiene-5α-acetoxy-10β-ol (multiple
Paclitaxel
Chemical compound
originally identified from plants of the genus Taxus (yews), and feature a taxadiene core. Paclitaxel (Taxol) and docetaxel (Taxotere) are widely used as chemotherapy
Taxane
Class of oily organic compounds found in plants
is a monoterpenoid, a tropolone derivative. Humulene, a sesquiterpene. Taxadiene, a diterpene, precursor to the diterpenoid taxol, an anticancer agent
Terpene
Chemical compound
reported in 2012 together with its conversion to the next Taxol precursor taxadiene. A multigram synthetic method was reported in 2015. GEN News Highlights
Taxadienone
Chemical compound
show whether taxine B could also be used as a pharmaceutical. Taxane Taxadiene Omacetaxine Graf, Engelbert; Kirfel, Armin; Wolff, Gerd-Joachim; Breitmaier
Taxine_alkaloids
In enzymology, a taxadiene 5alpha-hydroxylase (EC 1.14.99.37) is an enzyme that catalyzes the chemical reaction taxa-4,11-diene + AH2 + O2 ⇌ {\displaystyle
Taxadiene_5alpha-hydroxylase
Chemical compound
same accomplishment with Escherichia coli in 2000. 10-Deacetylbaccatin Taxadiene Han F, Kang LZ, Zeng XL, Ye ZW, Guo LQ, Lin JF (2014). "Bioproduction
Baccatin_III
Hydrocarbon compound containing one or more C=C bonds
compounds in nature Limonene, a monoterpene. Humulene, a sesquiterpene. Taxadiene, a diterpene, precursor to the diterpenoid taxol, an anticancer agent
Alkene
American biochemist
Yinghua; Coates, Robert M.; Croteau, Rodney; Christianson, David W. (2011). "Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis"
David_W._Christianson
Ongoing research into paclitaxel synthesis
C1–C2 bond. Ongoing research efforts are directed at the synthesis of taxadiene and taxadienone intermediates. The synthesis of related taxanes decinnamoyltaxinine
Paclitaxel_total_synthesis
Chemical compound
isolate derived from Taxus wallichiana. Taxusin can be used to synthesize taxadiene -diol and -triol derivatives via deoxygenation. Taxusin is found in the
Taxusin
Chemical compound
FPP precursor. Examples include: Myrcene synthase, pinene synthase, and taxadiene synthase Manville, J. F.; Kriz, C. D. (1977). "Juvabione and its analogues
Juvabione
Index of chemical compounds with the same molecular formula
diterpene Sclarene, a diterpene Stemarene, a diterpene Stemodene, a diterpene Taxadiene, a taxane diterpene This set index page lists chemical structure articles
C20H32
Protein domain
includes copalyl diphosphate synthase (kaurene synthase A). Tpsd includes taxadiene synthase, pinene synthase, and myrcene synthase. Tpse includes ent-kaurene
Terpene synthase C terminal domain
Terpene_synthase_C_terminal_domain
geranylhydroquinone 3′′-hydroxylase EC 1.14.14.175: ferruginol synthase EC 1.14.14.176: taxadiene 5α-hydroxylase EC 1.14.14.177: ultra-long-chain fatty acid ω-hydroxylase
List_of_EC_numbers_(EC_1)
Protein domain
includes copalyl diphosphate synthase (kaurene synthase A). Tpsd includes taxadiene synthase, pinene synthase, and myrcene synthase. Tpse includes ent-kaurene
Terpene synthase N terminal domain
Terpene_synthase_N_terminal_domain
15: myrcene synthase EC 4.2.3.16: (4S)-limonene synthase EC 4.2.3.17: taxadiene synthase EC 4.2.3.18: abietadiene synthase EC 4.2.3.19: ent-kaurene synthase
List_of_EC_numbers_(EC_4)
- taq polymerase - TATA box - taurochenodeoxycholate 6α-hydroxylase - taxadiene 5alpha-hydroxylase - taxane 10beta-hydroxylase - TAZ zinc finger - Tbf5
Index of molecular biology articles
Index_of_molecular_biology_articles
TAXADIENE
TAXADIENE
TAXADIENE
TAXADIENE
Boy/Male
Indian
Leopard
Boy/Male
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi
A Famous King
Male
German
Pet form of German Dieter, DIDI means "warrior of the people." Compare with feminine Didi.
Boy/Male
Hindu
Controller of the senses, Lord Hanuman
Boy/Male
Tamil
Narottam | நரோதà¯à®¤à®®
Best among men, Lord Vishnu
Boy/Male
Bengali, Gujarati, Hindu, Indian, Tamil
Enjoying Person
Boy/Male
Norse Swedish American English Teutonic German
Wolf.
Girl/Female
Indian, Punjabi, Sikh
Lamp of Happiness
Girl/Female
Biblical
Valley of grace.
Boy/Male
Gujarati, Hindu, Indian, Kannada, Marathi, Sanskrit
Karna
TAXADIENE
TAXADIENE
TAXADIENE
TAXADIENE
TAXADIENE