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SMARCA2

  • SMARCA2
  • Protein-coding gene in the species Homo sapiens

    transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene. The protein encoded by this gene is a member of the SWI/SNF family

    SMARCA2

    SMARCA2

    SMARCA2

  • Nicolaides–Baraitser syndrome
  • Medical condition

    is a rare genetic condition caused by de novo missense mutations in the SMARCA2 gene and has only been reported in fewer than 330 cases worldwide. NCBRS

    Nicolaides–Baraitser syndrome

    Nicolaides–Baraitser syndrome

    Nicolaides–Baraitser_syndrome

  • Mammalian SWI/SNF (BAF) complex
  • Chromatin remodeling complex

    ATP hydrolysis mediated by its catalytic subunits BRG1 (SMARCA4) or BRM (SMARCA2). The BAF complex exists in three subtypes, canonical BAF (cBAF), polybromo-associated

    Mammalian SWI/SNF (BAF) complex

    Mammalian_SWI/SNF_(BAF)_complex

  • Coffin–Siris syndrome
  • Medical condition

    mutations associated to this syndrome, including SOX11, ARID2, DPF2, PHF6, SMARCA2, SMARCA4, SMARCB1, SMARCC2, SMARCE1, SOX4. The diagnosis is generally based

    Coffin–Siris syndrome

    Coffin–Siris syndrome

    Coffin–Siris_syndrome

  • SWI/SNF
  • Subfamily of ATP-dependent chromatin remodeling complexes

    (2018-11-21). "Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant

    SWI/SNF

    SWI/SNF

    SWI/SNF

  • Camibirstat
  • Pharmaceutical compound

    of cancer. It is a small molecule that acts as a selective inhibitor of SMARCA2 and SMARCA4, which are key components of the SWI/SNF chromatin remodeling

    Camibirstat

    Camibirstat

    Camibirstat

  • SMARCB1
  • Protein-coding gene in the species Homo sapiens

    Cyclin-dependent kinase 8, Myc, P53, POLR2A, PPP1CA, PPP1CB, PPP1CC, PPP1R15A, SMARCA2, SMARCA4, SMARCC1, SMARCE1, SS18, and XPO1. ENSG00000275837 GRCh38: Ensembl

    SMARCB1

    SMARCB1

    SMARCB1

  • CEBPB
  • Protein-coding gene in humans

    HMGA1, HSF1, Nucleolar phosphoprotein p130, RELA, Serum response factor, SMARCA2, Sp1 transcription factor, TRIM28, and Zif268. Ccaat-enhancer-binding proteins

    CEBPB

    CEBPB

    CEBPB

  • POLR2A
  • Protein-coding gene in the species Homo sapiens

    GTF2F1, GTF2H4, MED21, MED26, PCAF, POLR2C, POLR2E, POLR2H, POLR2L, PQBP1, SMARCA2, SMARCA4 SMARCB1, SMYD3, SND1, SUPT5H, TAF11, TBP, TCEA1, TCERG1, and ZNF74

    POLR2A

    POLR2A

    POLR2A

  • ARID1B
  • Protein-coding gene in humans

    tumor suppressor gene. ARID1B has been shown to interact with SMARCA4 and SMARCA2. GRCh38: Ensembl release 89: ENSG00000049618 – Ensembl, May 2017 GRCm38:

    ARID1B

    ARID1B

    ARID1B

  • Prohibitin
  • Mammalian protein found in Homo sapiens

    shown to interact with: ANXA2 C-Raf, E2F1, HDAC1, P53, RB1, RBL1, RBL2, SMARCA2, and SMARCA4. Aurilide Fluorizoline Rocaglamide A Prohibitinn in insect

    Prohibitin

    Prohibitin

    Prohibitin

  • SMARCC1
  • Protein-coding gene in the species Homo sapiens

    factors. SMARCC1 has been shown to interact with: BAZ1B, ING1, SIN3A, SMARCA2, SMARCA4, and SMARCB1. GRCh38: Ensembl release 89: ENSG00000173473 – Ensembl

    SMARCC1

    SMARCC1

    SMARCC1

  • Oncogenomics
  • Sub-field of genomics

    essential-genes in process other than metabolism, namely the SMARCA4 and SMARCA2 subunits in the chromatin-remodeling SWI/SNF complex. Some oncogenes are

    Oncogenomics

    Oncogenomics

    Oncogenomics

  • ZNF821
  • Zinc Finger 821

    domain-containing protein 85B Two Hybrid Pooling Transcriptional Repressor SMARCA2 Probable global transcription activator SNF2L2 Two Hybrid Pooling Transcriptional

    ZNF821

    ZNF821

    ZNF821

  • SS18
  • Protein-coding gene in the species Homo sapiens

    synovial sarcoma. SS18 has been shown to interact with: EP300, MLLT10, SMARCA2, and SMARCB1. GRCh38: Ensembl release 89: ENSG00000141380 – Ensembl, May

    SS18

    SS18

    SS18

  • ACTL6A
  • Protein-coding gene in the species Homo sapiens

    carcinomas, it promotes metastasis. ACTL6A has been shown to interact with SMARCA2, Myc, Transformation/transcription domain-associated protein, RuvB-like

    ACTL6A

    ACTL6A

    ACTL6A

  • List of human protein-coding genes 7
  • 15299 SMAP2 HGNC:25082; Q8WU79 15300 SMARCA1 HGNC:11097; P28370 15301 SMARCA2 HGNC:11098; P51531 15302 SMARCA4 HGNC:11100; P51532 15303 SMARCA5 HGNC:11101;

    List of human protein-coding genes 7

    List_of_human_protein-coding_genes_7

  • Diana Hargreaves
  • American biologist

    Ho J, Sharp A, Shokhirev MN, Hargreaves DC. Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4. Mol

    Diana Hargreaves

    Diana Hargreaves

    Diana_Hargreaves

  • Transcription coregulator
  • Proteins that help regulate transcription

    SWI/SNF family chromatin structure remodeling complex ISWI protein SMARCA1, SMARCA2 Coactivator (genetics) Corepressor (genetics) Nuclear receptor coregulators

    Transcription coregulator

    Transcription_coregulator

  • SIN3A
  • Protein-coding gene in the species Homo sapiens

    OGT, PHF12, Promyelocytic leukemia protein, RBBP4, RBBP7, SAP130, SAP30, SMARCA2, SMARCA4, SMARCC1, SUDS3, TAL1, and Zinc finger and BTB domain-containing

    SIN3A

    SIN3A

    SIN3A

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Online names & meanings

  • Chann
  • Boy/Male

    American, British, English, Hindu, Indian, Irish, Punjabi, Sikh

    Chann

    Wise; Young Wolf; Beauteous; Beloved

  • Sriramya
  • Girl/Female

    Indian, Telugu

    Sriramya

    Lovable

  • TÓFA
  • Female

    Norse

    TÓFA

    Feminine form of Old Norse Tófi, a short form of names starting with Torf- or Torv-, TÓFA means "Þórr" or "thunder."

  • Zoheir
  • Boy/Male

    Arabic, Muslim

    Zoheir

    Glare

  • Shukrallah
  • Boy/Male

    Arabic, Muslim

    Shukrallah

    The Thanks of Allah

  • Grater
  • Surname or Lastname

    English

    Grater

    English : from Old French grateor, gratour, gratier ‘one who grates’, hence possibly an occupational name for a furbisher.German (Gräter) : see Graeter.

  • Sevitha | ஸேவீதா
  • Girl/Female

    Tamil

    Sevitha | ஸேவீதா

    Cherished

  • Curt
  • Male

    English

    Curt

    Short or Little

  • Floss
  • Girl/Female

    Latin

    Floss

    The mythological Roman goddess of flowers. Diminutive of Florence: From 'florentius' or...

  • Zola
  • Boy/Male

    Arabic, Hindu, Indian, Italian, Muslim

    Zola

    Moon; Lump of Earth

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SMARCA2

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SMARCA2