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SLAMF7

  • SLAMF7
  • Protein-coding gene in humans

    member 7 is a protein that in humans is encoded by the SLAMF7 gene. The surface antigen CD319 (SLAMF7) is a robust marker of normal plasma cells and malignant

    SLAMF7

    SLAMF7

    SLAMF7

  • Elotuzumab
  • Pharmaceutical drug

    targets the Signaling Lymphocytic Activation Molecule Family member 7 (SLAMF7) through two mechanisms. In May 2014, it was granted breakthrough therapy

    Elotuzumab

    Elotuzumab

  • Multiple myeloma
  • Cancer of plasma cells

    disappears rapidly ex vivo. Recently, however, the surface antigen CD319 (SLAMF7) was discovered to be considerably more stable and allows robust isolation

    Multiple myeloma

    Multiple myeloma

    Multiple_myeloma

  • Signaling lymphocytic activation molecule
  • Protein family

    FimH) SLAMF3 (CD229, LY9) SLAMF4 (CD244, 2B4) SLAMF5 (CD84) SLAMF6 (CD352) SLAMF7 (CD319, CRACC) SLAMF8 (CD353) SLAMF9 SLAMFs are CD2-related surface receptors

    Signaling lymphocytic activation molecule

    Signaling_lymphocytic_activation_molecule

  • Plasma cell
  • White blood cell that secretes large volumes of antibodies

    is expressed at high levels. Another important surface antigen is CD319 (SLAMF7). This antigen is expressed at high levels on normal human plasma cells

    Plasma cell

    Plasma cell

    Plasma_cell

  • Cancer immunotherapy
  • Artificial stimulation of the immune system to treat cancer

    targets the Signaling Lymphocytic Activation Molecule Family member 7 (SLAMF7) through two mechanisms. In May 2014, it was granted breakthrough therapy

    Cancer immunotherapy

    Cancer immunotherapy

    Cancer_immunotherapy

  • List of therapeutic monoclonal antibodies
  • Elgemtumab mab human ERBB3 (HER3) cancer Elotuzumab Empliciti mab humanized SLAMF7 Y multiple myeloma Elsilimomab mab mouse IL-6 Emactuzumab mab humanized

    List of therapeutic monoclonal antibodies

    List of therapeutic monoclonal antibodies

    List_of_therapeutic_monoclonal_antibodies

  • Monoclonal antibody therapy
  • Form of immunotherapy

    elotuzumab Empliciti Bristol-Myers Squibb 11/30/2015 intravenous humanized SLAMF7 Multiple myeloma 761035 Link[dead link] emicizumab-kxwh Hemlibra Genentech

    Monoclonal antibody therapy

    Monoclonal antibody therapy

    Monoclonal_antibody_therapy

  • List of human clusters of differentiation
  • CDCP1 phosphorylation in tumors is currently under investigation. CD319 SLAMF7, a marker of normal plasma cells and malignant plasma cells in multiple

    List of human clusters of differentiation

    List_of_human_clusters_of_differentiation

  • V-set domain
  • Protein domain

    SIGLEC7; SIGLEC8; SIGLEC9; SIRPA; SIRPB1; SIRPD; SIRPG; SISP1; SLAMF6; SLAMF7; TAPBPL; TCRA; TCRB; TIMD4; TRA@; TRAV20; TRBC1; TRBV19; TRBV3-1; TRBV5-4;

    V-set domain

    V-set domain

    V-set_domain

  • List of human protein-coding genes 7
  • Q9P270 14854 SLAMF1 HGNC:10903; Q13291 14855 SLAMF6 HGNC:21392; Q96DU3 14856 SLAMF7 HGNC:21394; Q9NQ25 14857 SLAMF8 HGNC:21391; Q9P0V8 14858 SLAMF9 HGNC:18430;

    List of human protein-coding genes 7

    List_of_human_protein-coding_genes_7

  • Outline of immunology
  • Overview of and topical guide to immunology

    (CD48) SLAMF3 (CD229, LY9) SLAMF4 (CD244) SLAMF5 (CD84) SLAMF6 (CD352) SLAMF7 (CD319) SLAMF8 (CD353) SLAMF9 Cadherins Selectins E-selectin L-selectin

    Outline of immunology

    Outline_of_immunology

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Online names & meanings

  • Kritika | கரதிகா 
  • Girl/Female

    Tamil

    Kritika | கரதிகா 

    Name of a star, Well starred, From the Nakshatra Kritika

  • Vishwdeep | விஷ்வதீப 
  • Boy/Male

    Tamil

    Vishwdeep | விஷ்வதீப 

    Big lighting

  • Suham | ஸுஹாம 
  • Boy/Male

    Tamil

    Suham | ஸுஹாம 

    Tirandaj

  • TA-BU-BU
  • Female

    Egyptian

    TA-BU-BU

    , a priestess of the goddess Bast.

  • Xaven
  • Girl/Female

    Arabic

    Xaven

    Short

  • Lanning
  • Surname or Lastname

    English (Dorset and Somerset)

    Lanning

    English (Dorset and Somerset) : unexplained.Dutch : patronymic from a short form of the personal name Julianus (see Julian).

  • Averil
  • Boy/Male

    American, Anglo, British, English

    Averil

    Wild Boar; Born in April; Boar-warrior

  • Ramos
  • Boy/Male

    Sanskrit

    Ramos

    Pleasing. Rama was mythological seventh incarnation of Vishnu and his story is told in the Hindi...

  • Suprasanna
  • Boy/Male

    Hindu, Indian, Kannada, Malayalam, Marathi, Telugu

    Suprasanna

    Ever Cheerful and Beaming; Goddess Lakshmi

  • Talia
  • Girl/Female

    Hebrew American Greek

    Talia

    Dew of heaven.

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SLAMF7

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