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Protein-coding gene in the species Homo sapiens
protein 3 (SH2B3), also known as lymphocyte adapter protein (LNK), is a protein that in humans is encoded by the SH2B3 gene on chromosome 12. SH2B3 is ubiquitously
SH2B3
Autoimmune disease of the liver
26, implicating many genes involved in cytokine regulation such as TYK2, SH2B3 and TNFSF11. A study of over 2,000 patients identified a gene, POGLUT1,
Primary_biliary_cholangitis
Protein domain
PIK3R2; PIK3R3; PLCG1; PLCG2; PTK6; PTPN11; PTPN6; RASA1 SH2B1; SH2B2; SH2B3; SH2D1A; SH2D1B; SH2D2A; SH2D3A; SH2D3C; SH2D4A; SH2D4B; SH2D5; SH2D6; SH3BP2;
SH2_domain
Clinical Significance
RGNEF, ROCK1, ROCK2, RTKN, SBF1, SBF2, SCAP2, SGEF, SH2B, SH2B1, SH2B2, SH2B3, SH3BP2, SKAP1, SKAP2, SNTA1, SNTB1, SNTB2, SOS1, SOS2, SPATA13, SPNB4,
Pleckstrin_homology_domain
Type of protein
protein 1 SH2B1 – SH2B adaptor protein 1 SH2B2 – SH2B adaptor protein 2 SH2B3 – SH2B adaptor protein 3 SH2D3A -SH2 domain containing 3A SH2D3C – SH2 domain
Signal transducing adaptor protein
Signal_transducing_adaptor_protein
Protein-coding gene in humans
to interact with: BRCA2, CD29 CASR, FBLIM1, FILIP1, FLNB, NPHP1, RALA, SH2B3, TRIO, and VHL. GRCh38: Ensembl release 89: ENSG00000196924 – Ensembl, May
FLNA
Protein-coding gene in humans
include C3, SH2B3, and C1R—all of which are associated with immune functions. C3 and C1R are involved in the complement system while SH2B3 is a protein
FAM155B
Protein-coding gene in humans
RAD21, SMC3, SMC1A, NIPBL, SUZ12, PRC2, JAK1, JAK2, JAK3, MPL, KRAS, NRAS, SH2B3, and MIR125B2 which is the gene for microRNA MiR125B2. Diamond–Blackfan
GATA1
Blood marrow cancer originating in megakaryoblast cells
SMC3, SMC1A, NIPBL, SUZ12, PRC2, JAK1, JAK2, JAK3, MPL, KRAS, NRAS, and SH2B3. At least one but probably several of these mutations, whether occurring
Acute megakaryoblastic leukemia
Acute_megakaryoblastic_leukemia
Q96EQ0 14694 SH2B1 HGNC:30417; Q9NRF2 14695 SH2B2 HGNC:17381; O14492 14696 SH2B3 HGNC:29605; Q9UQQ2 14697 SH2D1A HGNC:10820; O60880 14698 SH2D1B HGNC:30416;
List of human protein-coding genes 7
List_of_human_protein-coding_genes_7
Medical condition
SMC3, SMC1A, NIPBL, SUZ12, PRC2, JAK1, JAK2, JAK3, MPL, KRAS, NRAS, and SH2B3. The development and progression of TMD result from collaborations between
Transient myeloproliferative disease
Transient_myeloproliferative_disease
SH2B3
SH2B3
SH2B3
SH2B3
Girl/Female
Tamil
Dharsini | தாரஸீநீ
Someone who see
Boy/Male
Tamil
Darshish | தரà¯à®·à¯€à®·Â
Contemplation, Examination
Surname or Lastname
English
English : variant spelling of Leggett.
Surname or Lastname
English (Kent)
English (Kent) : origin unidentified; probably a habitational name from a lost or unidentified place, perhaps an altered form of Rayford.
Girl/Female
Muslim/Islamic
Old Ancient
Boy/Male
Tamil
Dam=cord, Udara=stomach, Lord when he was tied with a rope around his waist
Boy/Male
Latin
Constant.
Boy/Male
Muslim
A prophets name
Girl/Female
Arabic, Muslim
Blooming; Happy
Girl/Female
Latin
Honor.
SH2B3
SH2B3
SH2B3
SH2B3
SH2B3