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SDHB

  • SDHB
  • Protein-coding gene in the species Homo sapiens

    subunit, mitochondrial (SDHB) also known as iron-sulfur subunit of complex II (Ip) is a protein that in humans is encoded by the SDHB gene. The succinate

    SDHB

    SDHB

    SDHB

  • Succinate dehydrogenase
  • Enzyme

    The first two subunits, a flavoprotein (SDHA) and an iron-sulfur protein (SDHB), form a hydrophilic head where enzymatic activity of the complex takes place

    Succinate dehydrogenase

    Succinate dehydrogenase

    Succinate_dehydrogenase

  • Agriculture in California
  • Agriculture is a significant sector in California's economy, producing nearly US$59.4 billion in revenue in 2023[update]. There are more than 400 commodity

    Agriculture in California

    Agriculture in California

    Agriculture_in_California

  • Pheochromocytoma
  • Tumor of the adrenal medulla which secretes adrenal hormones

    diagnostic workup. Loss of SDHB staining is indicative of SDHx-related pathogenesis and is particularly noted in tumors with SDHB pathogenic variants. Inhibin

    Pheochromocytoma

    Pheochromocytoma

    Pheochromocytoma

  • LYRM protein
  • Protein superfamily

    LYR tripeptide—a motif frequently found in mitochondrial proteins such as SDHB, NDUFAF3, or mitochondrial ribosomal proteins—but that lack the additional

    LYRM protein

    LYRM protein

    LYRM_protein

  • SDHD
  • Protein-coding gene in the species Homo sapiens

    other transmembrane subunit is SDHC. The SDHC/SDHD dimer is connected to the SDHB electron transport subunit which, in turn, is connected to the SDHA subunit

    SDHD

    SDHD

    SDHD

  • Paraganglioma
  • Rare neuroendocrine tumour

    SDHC (previously PGL3) and SDHB have been identified as causing familial head and neck paragangliomas. Mutations of SDHB play an important role in familial

    Paraganglioma

    Paraganglioma

    Paraganglioma

  • Succinate dehydrogenase complex subunit C
  • Protein found in humans

    other transmembrane subunit is SDHD. The SDHC/SDHD dimer is connected to the SDHB electron transport subunit which, in turn, is connected to the SDHA subunit

    Succinate dehydrogenase complex subunit C

    Succinate dehydrogenase complex subunit C

    Succinate_dehydrogenase_complex_subunit_C

  • Oncometabolism
  • Study of cell metabolism in the development of cancer

    patients for SDH mutation testing in early stages of cancer. The absence of SDHB in IHC staining would be linked to the presence of SDH oncogene mutations

    Oncometabolism

    Oncometabolism

    Oncometabolism

  • Mitochondrial complex II deficiency
  • Medical condition

    SDH plays a key role in metabolism; the catalytic end, made up of SDHA and SDHB oxidizes succinate to fumarate in the tricarboxylic acid (TCA) cycle. The

    Mitochondrial complex II deficiency

    Mitochondrial complex II deficiency

    Mitochondrial_complex_II_deficiency

  • Carney triad
  • Multiple neoplasia syndrome

    gene pathway involving the succinate dehydrogenase subunits SDHD, SDHC and SDHB. OMIM - Online Mendelian Inheritance in Man. Carney Triad (OMIM 604287) Carney

    Carney triad

    Carney triad

    Carney_triad

  • SDHAF1
  • Protein-coding gene in the species Homo sapiens

    and promotes the maturation of the SDHB subunit of the SDH catalytic dimer. The iron-sulfur (Fe-S) protein subunit SDHB is required for functional succinate

    SDHAF1

    SDHAF1

    SDHAF1

  • WSP New Zealand
  • Engineering services consulting firm

    Redevelopment. In 2019 the SDHB released the official design plans for the redevelopment of Dunedin Hospital. On 17 May 2019, the SDHB announced that WSP Opus

    WSP New Zealand

    WSP_New_Zealand

  • Mitochondrial myopathy
  • Muscle disorders caused by mitochondrial dysfunction

    reductase deficiency; succinate dehydrogenase deficiency) SDHA, SDHAF1, SDHD, SDHB AR PS252011 cytochrome b of complex III (MTCYB); Exercise intolerance; multisystem

    Mitochondrial myopathy

    Mitochondrial myopathy

    Mitochondrial_myopathy

  • Electron transport chain
  • Energy-producing metabolic pathway

    succinate dehydrogenase [ubiquinone] iron–sulfur subunit mitochondrial (SDHB); succinate dehydrogenase complex subunit C (SDHC); and succinate dehydrogenase

    Electron transport chain

    Electron_transport_chain

  • Springbok
  • Antelope of southwest and south Africa

    in genes related to the mitochondrial electron transport chain (NDUFA10, SDHB, UQCRC2 and ATP5F1B). Two mutations unique to the Antilopinae (SUOX and NLN)

    Springbok

    Springbok

    Springbok

  • Ganglioneuroma
  • Benign tumor of the autonomic nervous system

    somatic mosaic origin, such as RET proto-oncogene, CDKN1B, Neurofibromin, SDHB, SDHC, SDHD, VHL, and EPAS1, in association with Pacak-Zhuang syndrome. Pathologically

    Ganglioneuroma

    Ganglioneuroma

    Ganglioneuroma

  • Arthur S. Tischler
  • American scientist and medical doctor

    to study neuroendocrine tumors. In 2020, he co-developed RS0, the first SDHB-mutant, SDH-deficient pheochromocytoma model. Tischler served as President

    Arthur S. Tischler

    Arthur_S._Tischler

  • Hereditary cancer syndrome
  • Inherited genetic condition that predisposes a person to cancer

    (succinate:ubiquinone oxidoreductase) subunit genes (SDHD, SDHAF2, SDHC, SDHB). PGL-1 is associated with SDHD mutation, and most PGL-1 individuals with

    Hereditary cancer syndrome

    Hereditary cancer syndrome

    Hereditary_cancer_syndrome

  • Moana Theodore
  • New Zealand epidemiologist

    Society Te Apārangi. Retrieved 17 June 2023. Houlahan, Mike (9 June 2022). "SDHB meets for last time before restructure". Otago Daily Times. Retrieved 24

    Moana Theodore

    Moana Theodore

    Moana_Theodore

  • Chromosome 1
  • Human chromosome

    encoding protein Sterile alpha motif domain containing 11 SDC3: Syndecan-3 SDHB (1p36) SFPQ (1p34): encoding protein Splicing factor proline and glutamine

    Chromosome 1

    Chromosome 1

    Chromosome_1

  • SDHA
  • Protein-coding gene in humans

    ubiquinol). Electrons removed from succinate transfer to SDHA, transfer across SDHB through iron sulphur clusters to the SDHC/SDHD subunits on the hydrophobic

    SDHA

    SDHA

    SDHA

  • Housekeeping gene
  • Gene which maintains basic cellular functions

    metabolism SDHA NM_004168 Succinate Dehydrogenase subunit A SDHAF2 NM_017841 SDHB NM_002973 Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH)

    Housekeeping gene

    Housekeeping_gene

  • Dave Cull
  • New Zealand politician (1950–2021)

    shock entrant in SDHB race". Otago Daily Times. Retrieved 27 August 2019. Houlahan, Mike (13 October 2019). "Cull and Chambers top SDHB poll". Otago Daily

    Dave Cull

    Dave Cull

    Dave_Cull

  • Fluxapyroxad
  • Chemical compound

    Anastasios N.; Karaoglanidis, George S. (2013). "Differential Effect of SdhB Gene Mutations on the Sensitivity to SDHI Fungicides in Botrytis cinerea"

    Fluxapyroxad

    Fluxapyroxad

    Fluxapyroxad

  • Hypoxia-inducible factor
  • Protein that responds to low oxygen

    transfer in the succinate dehydrogenase complex due to mutations in the SDHB or SDHD genes can cause a build-up of succinate that inhibits HIF prolyl-hydroxylase

    Hypoxia-inducible factor

    Hypoxia-inducible_factor

  • Anthony Gill (professor)
  • Australian pathologist & professor (born 1972)

    Clinicopathologic Series of 36 Tumors From 27 Patients". "Immunohistochemistry for SDHB Divides Gastrointestinal Stromal Tumors (GISTs) into 2 Distinct Types". Cancer

    Anthony Gill (professor)

    Anthony Gill (professor)

    Anthony_Gill_(professor)

  • Ferredoxin
  • Iron–sulfur proteins that mediate electron transfer in metabolic reactions

    via four Cys residues.[citation needed] 2Fe–2S: AOX1; FDX1; FDX2; NDUFS1; SDHB; XDH; 4Fe–4S: ABCE1; DPYD; NDUFS8; Mortenson LE, Valentine RC, Carnahan JE

    Ferredoxin

    Ferredoxin

  • COVID-19 vaccination in New Zealand
  • Ongoing COVID-19 vaccine programme in New Zealand

    District Health Board (SDHB) confirmed that mass COVID-19 vaccination clinics would be opened in Dunedin and Invercargill. The SDHB also confirmed that it

    COVID-19 vaccination in New Zealand

    COVID-19 vaccination in New Zealand

    COVID-19_vaccination_in_New_Zealand

  • Agriculture in Maryland
  • widespread resistance to SDHIs here. They find several etiologies, with various sdhB alleles producing the resistance. H272R resistance to boscalid, H272R or

    Agriculture in Maryland

    Agriculture in Maryland

    Agriculture_in_Maryland

  • Gastrointestinal stromal tumor
  • Human disease (cancer)

    pathway involving the succinate dehydrogenase (SDH) subunits SDHD, SDHC and SDHB. Approximately 85% GISTs are associated with an abnormal c-KIT pathway. c-KIT

    Gastrointestinal stromal tumor

    Gastrointestinal stromal tumor

    Gastrointestinal_stromal_tumor

  • Iron response element
  • RNA family

    one without. Genes known to contain IREs include FTH1, FTL, TFRC, ALAS2, Sdhb, ACO2, Hao1, SLC11A2 (encoding DMT1), NDUFS1, SLC40A1 (encoding the ferroportin)

    Iron response element

    Iron response element

    Iron_response_element

  • ISCU
  • Mitochondrial protein involved in iron–sulfur cluster biosynthesis

    including 79 co-complex interactions. ISCU appears to interact with ISCS, NUP62, SDHB, HPRT1, CCDC172, GOLGA2, IKZF1, KRT40, AGTRAP, NECAB2, FAM9B, BANP, LNX1

    ISCU

    ISCU

    ISCU

  • Cephaloleia trilineata
  • Species of beetle

    Taxon identifiers Cephaloleia trilineata Wikidata: Q2085259 BioLib: 796703 CoL: SDHB EoL: 27518505 GBIF: 6272992 ITIS: 843101 Open Tree of Life: 3371969

    Cephaloleia trilineata

    Cephaloleia trilineata

    Cephaloleia_trilineata

  • List of human protein-coding genes 7
  • Q9NX18 14442 SDHAF3 HGNC:21752; Q9NRP4 14443 SDHAF4 HGNC:20957; Q5VUM1 14444 SDHB HGNC:10681; P21912 14445 SDHC HGNC:10682; Q99643 14446 SDHD HGNC:10683; O14521

    List of human protein-coding genes 7

    List_of_human_protein-coding_genes_7

  • 2015 Otago flood
  • 2015 flood in Otago, New Zealand

    Health Board (SDHB) also established an emergency operations centre to ensure that staff were able to travel safely to and from work. The SDHB also assisted

    2015 Otago flood

    2015_Otago_flood

  • NKAPD1
  • Human NKAPD1 Protein

    "Simple and rapid characterization of novel large germline deletions in SDHB, SDHC and SDHD-related paraganglioma". Clinical Genetics. 91 (4): 536–544

    NKAPD1

    NKAPD1

    NKAPD1

  • Jonathan Coleman (politician)
  • New Zealand politician (born 1966)

    minutes, with Coleman telling Mr Garbutt the Southern District Health Board (SDHB) was his ''number 1'' priority in respect of its budget woes. Coleman announced

    Jonathan Coleman (politician)

    Jonathan Coleman (politician)

    Jonathan_Coleman_(politician)

  • Southern District Health Board
  • Former health board in New Zealand

    2020. Retrieved 3 May 2020. "Grant hopes new structure will 'future-proof' SDHB". Stuff. 3 December 2019. Retrieved 14 November 2020. "Statistical area 1

    Southern District Health Board

    Southern District Health Board

    Southern_District_Health_Board

  • List of OMIM disorder codes
  • 260660; TBX15 Cowden syndrome; 158350; PTEN Cowden-like syndrome; 612359; SDHB Cowden-like syndrome; 612359; SDHD CPT deficiency, hepatic, type IA; 255120;

    List of OMIM disorder codes

    List_of_OMIM_disorder_codes

  • Hereditary diffuse gastric cancer
  • Medical condition

    cause HDGC, but possible associated genes include CTNNA1, BRCA2, STK11, SDHB, PRSS1, ATM, MSR1, and PALB2. Surgical removal of the stomach (gastrectomy)

    Hereditary diffuse gastric cancer

    Hereditary diffuse gastric cancer

    Hereditary_diffuse_gastric_cancer

  • List of chairpersons of district health boards
  • November 2013. Retrieved 18 April 2020. Goodwin, Eileen (19 March 2015). "New SDHB chairman, Butterfield to go". Otago Daily Times. Retrieved 18 April 2020

    List of chairpersons of district health boards

    List_of_chairpersons_of_district_health_boards

  • SUCNR1
  • Protein-coding gene in the species Homo sapiens

    the succinate dehydrogenase heterotetrmer, i.e., the SDHD, SDHA, SDHC, and SDHB genes (inactivation of any one of these genes causes paraganglioma cells

    SUCNR1

    SUCNR1

    SUCNR1

AI & ChatGPT searchs for online references containing SDHB

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Online names & meanings

  • Gunakar
  • Boy/Male

    Bengali, Hindu, Indian, Kannada, Telugu

    Gunakar

    An Ancient King

  • Mrinmoy
  • Boy/Male

    Bengali, Hindu, Indian

    Mrinmoy

    Anything that is Made out of Mud; A Pot Made by Soil; Made out of Earth

  • Jade
  • Girl/Female

    African, American, Australian, British, Chinese, Christian, Danish, English, French, Indian, Jamaican, Spanish

    Jade

    Precious Green Stone; The Most Beautiful Stone; Green Gemstone

  • Naik
  • Boy/Male

    Hindu, Indian

    Naik

    A Chief; Leader; Head of Group

  • Gere
  • Surname or Lastname

    Americanized form of German Gehr.English

    Gere

    Americanized form of German Gehr.English : perhaps a variant of Geary 3.Hungarian : from a reduced form of the personal name Gergely, Latin Gregorius (see Gregory).

  • Mahuli
  • Girl/Female

    Hindu

    Mahuli

    Melodious, A musical Raag

  • Flavia
  • Girl/Female

    Italian Latin

    Flavia

    Blond.

  • Falan
  • Boy/Male

    Hindu, Indian

    Falan

    Beautiful

  • Ahava
  • Biblical

    Ahava

    essence; being; generation

  • Sayfullah
  • Boy/Male

    Arabic, Muslim

    Sayfullah

    Sword of Allah

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SDHB

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