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DNA region replicating from a single origin
A replicon is a region of an organism's genome that is independently replicated from a single origin of replication[citation needed]. A bacterial chromosome
Replicon_(genetics)
Topics referred to by the same term
Replicon may refer to: Replicon (genetics), a region of DNA or RNA that replicates from a single origin of replication Replicon (company), a software
Replicon
Sequence in a genome
single origin or initiation event is defined as the replicon. A fundamental feature of the replicon hypothesis is that it relies on positive regulation
Origin_of_replication
Canadian software company
Replicon is a Calgary-based software-as-a-service (SaaS) company that makes software for time tracking, advanced project management, task collaboration
Replicon_(company)
Next-generation mRNA vaccine/therapeutic
influences the performance of various positive-stranded RNA virus-based replicons". Scientific Reports. 14 (1): 17634. Bibcode:2024NatSR..1417634M. doi:10
Self-amplifying_RNA
Small DNA molecule within a cell
may make additional edits from the submission. Plasmids are considered replicons, units of DNA capable of replicating autonomously within a suitable host
Plasmid
Are a class of bacterial replicons (replicating DNA molecules)
secondary chromosomes, are a class of bacterial replicons (replicating DNA molecules). These replicons are called "chromids" because they have characteristic
Secondary_chromosome
Biological process
U. (2006-06-30). "Live-Cell Imaging Reveals Replication of Individual Replicons in Eukaryotic Replication Factories". Cell. 125 (7): 1297–1308. doi:10
DNA_replication
Biological process
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Cell_division
Process of virus reproduction
nucleic acid into the host bacterium's genome or formation of a circular replicon in the bacterial cytoplasm. In this condition the bacterium continues to
Lysogenic_cycle
Type of repeated DNA sequence
Iterons are directly repeated DNA sequences which play an important role in regulation of plasmid copy number in bacterial cells. It is one among the three
Iteron
assembly process. Some of these viral nonstructural protein functions are replicon formation, immunomodulation, and transactivation of viral structural protein
Viral_protein
Numerous key discoveries in biology have emerged from studies of RNA (ribonucleic acid), including seminal work in the fields of biochemistry, genetics
History_of_RNA_biology
DNA replication in eukaryotic organisms
form one replicon. After the formation of pre-initiation complex, when one replicon starts elongation, initiation starts in second replicon. Now, if the
Eukaryotic_DNA_replication
Agrobacterium). Systems in which T-DNA and vir genes are located on separate replicons are called T-DNA binary systems. T-DNA is located on the binary vector
Transfer_DNA_binary_system
Species of bacterium
pXO2 Size (bp) 5,227,293 181,677 94,829 Number of genes 5,508 217 113 Replicon coding (%) 84.3 77.1 76.2 Average gene length (nt) 800 645 639 G+C content
Bacillus_anthracis
Species of bacterium
for flagellin. These include fliC1C2–fliC3C4. The genome contains three replicons: a chromosome (~3.7 megabases), a chromid (pSymB; ~1.7 megabases), and
Ensifer_meliloti
carcinoma Repeat sequences Repetitive DNA Replica plating Replication fork Replicon Replisome Reporter gene Repression Repressor Reproductive cells Reproductive
Index_of_genetics_articles
Type of behavior of a dynamical system
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Self-replication
Virus responsible for hemorrhagic fever
effects in humans. A variety of other vaccines have been considered. Virus replicon particles (VRPs) were shown to be effective in guinea pigs, but lost efficacy
Marburg_virus
Theory that viruses predate cellular life
theorized to be direct descendants of the very first replicons to arise. These primordial soup dwelling replicons could have evolved into archaic virus-like structures
Virus_world_hypothesis
DNA sequence whose position in the genome is variable
around within a genome, or that can be transferred from one species or replicon to another. MGEs are found in all organisms. In humans, approximately 50%
Mobile_genetic_elements
Process of copying a segment of DNA into RNA
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Transcription_(biology)
Inflammation of the udder in cows
Eliane (2026). "Antimicrobial Resistance, Virulence Factors and Plasmid Replicon Patterns of Klebsiella pneumoniae and Klebsiella grimontii Isolates from
Mastitis_in_dairy_cattle
Small, circular replicating units of DNA
Minicircles are small (~4kb) circular replicons. They occur naturally in some eukaryotic organelle genomes. In the mitochondria-derived kinetoplast of
Minicircle
Vaccine against Marburg virus disease
vaccines are DNA vaccines or based on Venezuelan equine encephalitis virus replicons, vesicular stomatitis Indiana virus (VSIV) or filovirus-like particles
Marburg_vaccine
Gene editing method
"Highly efficient homology-directed repair using CRISPR/Cpf1-geminiviral replicon in tomato". Plant Biotechnology Journal. 18 (10): 2133–2143. doi:10.1111/pbi
CRISPR_gene_editing
Medication
against multiple HCV genotypes 1–6 and key mutants (GT1b, IC50 = 0.2–0.4 nM; replicon GT1b, EC50 = 1.6 nM). Danoprevir has been evaluated in an open-label, single
Danoprevir
British-born Canadian voice actor
I. Joe Extreme Tracker 1995–96 Skysurfer Strike Force Micky Flannigan, Replicon, Chronozoid 1995–97 Street Fighter Fei Long, E. Honda, Balrog, Vega, T
Paul_Dobson_(actor)
DNA vector used in bioengineering
(1989-05-05). "Genetic analysis of the lytic replicon of bacteriophage P1. II. Organization of replicon elements". Journal of Molecular Biology. 207 (1):
P1-derived artificial chromosome
P1-derived_artificial_chromosome
Cellular process of protein synthesis
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Translation_(biology)
Collection of the total genomic DNA from a single organism
plasmid replicon, which ensures only one copy of the vector is present in a cell. However, there is a second P1 replicon- called the P1 lytic replicon- that
Genomic_library
DNA that does not code for proteins
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Non-coding_DNA
Type of vaccine
"Influenza virus (A/HK/156/97) hemagglutinin expressed by an alphavirus replicon system protects chickens against lethal infection with Hong Kong-origin
MRNA_vaccine
Protein
that activates initiation of DNA replication in bacteria. Based on the Replicon Model, a positively active initiator molecule contacts with a particular
DnaA
Realm of viruses
both retroelements and the viral RdRp are descended from a capsidless RNA replicon that was present in the RNA world. The unclassified phylum Taraviricota
Riboviria
the International Society for Antiviral Research (2017). "Hepatitis C replicon system and drug development - The Lasker Foundation". The Lasker Foundation
Michael_J._Sofia
1995 American TV series or program
from missions or battles. She seems to have a crush on Skysurfer One. Replicon - A blue-skinned shapeshifter who turns parts of his body into automatic
Skysurfer_Strike_Force
Manipulation of an organism's genome
set of broad-host-range cloning and expression vectors based on the RK2 replicon", Appl. Environ. Microbiol. 1997, Volume 63, Issue 2, p. 370 Lanigan, T
Genetic_engineering
Kingdom of viruses
"Taraviricota", along with its position, suggests that it may represent a form of replicon characteristic of the peptide-RNA world, one that all RNA viruses descended
Orthornavirae
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Helper_dependent_virus
Mitochondrion-derived organelle
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Hydrogenosome
Species of bacterium
R, Schwager S, Jenul C, Vergunst A, et al. (February 2014). "The third replicon of members of the Burkholderia cepacia Complex, plasmid pC3, plays a role
Burkholderia_cenocepacia
Genetic material
essential for replication and one or more selectable markers. One such "mini-replicon" is the plasmid PFF1, which is 5873 basepairs long. PFF1 consists of an
RK2_plasmid
American virologist
2016. "2016 Lasker~DeBakey Clinical Medical Research Award: Hepatitis C replicon system and drug development". The Lasker Foundation. 2016. Retrieved November
Charles_M._Rice
Indian-American biologist (born 1957)
Loretz, Carol; Seto, Jason (1998-11-01). "Snapshot of a Large Dynamic Replicon in a Halophilic Archaeon: Megaplasmid or Minichromosome?". Genome Research
Shiladitya_DasSarma
Realm of viruses
archaeal genomes". Kazlauskas et al. 2019, sec. "Global network of the HUH replicons". Zhou et al. 2025, p. 5. Liu, Dyall-Smith & Oksanen 2022, sec. "Biology"
Pleomoviria
Genus of viruses
engineered to create replicon vectors which efficiently induce humoral and T-cell immune responses. In these contexts, replicons have been termed self-amplifying
Alphavirus
Species of bacterium
evolutionary relationships between bacteria. Also relevant in determining if the replicon is a chromosome is whether it represents a significant percentage of the
Vibrio_cholerae
Vaccine containing DNA
how alphavirus replicons raise an immune response, but it may be due to the high levels of protein expressed by this vector, replicon-induced cytokine
DNA_vaccine
Protein family
called replicon clusters. Each cluster's replicons are similar in length, but individual clusters have replicons of varying length. These replicons all have
Origin_recognition_complex
Discipline in genetics
having a single contiguous sequence with no ambiguities representing each replicon. The DNA sequence assembly alone is of little value without additional
Genomics
Type of DNA in bacterial genomes
linked to the right end of the T-DNA to be transformed along with a plasmid replicon and a selectable antibiotic (such as hygromycin)-resistance gene and can
Transfer_DNA
Virus or plasmid designed for gene expression in cells
in the same cell, the other would need to be of a different replicon, e.g. a p15A replicon-based plasmid such as the pACYC series of plasmids. Another
Expression_vector
Species of bacterium
resistance genes circulating along A. baumannii that can be clustered in replicon groups, and may be transferred from the extensively drug-resistant Acinetobacter
Acinetobacter_baumannii
Species of pathogenic bacterium found in water
vulnificus is approximately 5.3 Mbp. The genome is organized into two circular replicons, similar to that of V. cholerae, which also has a large and a small chromosome
Vibrio_vulnificus
Branch of virology
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Synthetic_virology
Human viral disease
ones are DNA vaccines or based on Venezuelan equine encephalitis virus replicons, vesicular stomatitis Indiana virus (VSIV) or filovirus-like particles
Marburg_virus_disease
Human infectious disease
advantage in the human body. The genome of B. pseudomallei consists of two replicons: chromosome 1 encodes housekeeping functions of the bacteria such as cell
Melioidosis
Tunisian car manufacturer
capacity is 600 units per year "Paris Show Curiosities: WallysCar Izis Jeep Replicon – Carscoops". carscoops.com. 2013. Retrieved 26 July 2013. equipped with
Wallyscar
Region on human chromosome 14
Delepine M, et al. (2002). "The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and
IGH@
1456-1460. Yang et al., “Characterization of the mobilization determinants of pAN12, a small replicon from Rhodococcus erythropolis AN12.” Plasmid 57, 71-81.
TraA
Population structure of viruses with a large number of variant genomes
quasispecies was adopted from a theory of the origin of life in which primitive replicons consisted of mutant distributions, as found experimentally with present-day
Viral_quasispecies
Phylogenetic group described in January 2024
EV; Nunoura, T (2026). "Identification of hot spring Obelisk-like RNA replicons and expanded diversity of the Obelisk superfamily". Nature Communications
Obelisk_(biology)
American virologist
reverse genetics. He and his colleague Ilya Frolov are developing alphavirus replicon vectored RVF vaccines for use in livestock and ultimately in humans. His
C._J._Peters
American researcher
E. A., Murapa, P., ... & Fuller, D. H. (2020). An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses
Darrick_Carter
Chemical compound
binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted
Alisporivir
Spanish microbiologist (born 1963)
present in the largest replicons of the Archaea Haloferax mediterranei and Haloferax volcanii and could be involved in replicon partitioning". Molecular
Francisco_Mojica
Parts of lagging strand in DNA replication
significantly larger number of replicons, about 50,000 or more; however, replication does not occur at the same time on all of the replicons. In eukaryotes, DNA
Okazaki_fragments
Titok, M. A.; et al. (2003). "Bacillus subtilis soil isolates: plasmid replicon analysis and construction of a new theta-replicating vector". Plasmid.
Pht01
Bacterial plasmid
IncF group. Since R1 is an IncFII plasmid, that means it carries the FII replicon. This plasmid subtype often carries blaCTX-M genes. There are 120 genes
R1_plasmid
Cell organelle in a few species
chromosome Genome Gene Gene duplication Non-coding DNA Origin of replication Replicon Endogenous viral element Provirus Prophage Endogenous retrovirus Transpoviron
Mitosome
Class of pharmaceutical drugs
crystallized X-ray structures, high-throughput screening, enzyme and cell based replicon assays, and animal models for screening, many potential drug candidates
NS5B_inhibitor
Class of enzymes
RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon Replication fork Lagging and leading strands Okazaki fragments Primer Replication
DNA_polymerase_epsilon
Protein domain
Sugden (2007). "The coupling of synthesis and partitioning of EBV's plasmid replicon is revealed in live cells". The EMBO Journal. 26 (19): 4252–4262. doi:10
Epstein–Barr virus nuclear antigen 1
Epstein–Barr_virus_nuclear_antigen_1
Species of virus
of HCV has been hampered by the narrow host range of HCV. The use of replicons has been successful but these have only been recently discovered. HCV
Hepatitis_C_virus
control systems, mobile phones, and browsers. SQLite, PostgreSQL Open-source Replicon Web application 1996 Provides employee time tracking, project time tracking
Comparison of time-tracking software
Comparison_of_time-tracking_software
Protein-coding gene in humans
RNASEH2A Helicase: HFM1 Primase: PRIM1 PRIM2 Both Origin of replication/Ori/Replicon Replication fork Lagging and leading strands Okazaki fragments Primer Replication
POLE_(gene)
Process that prevents the expression of a gene
interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells". Proceedings of the National Academy
Gene_silencing
2007). Yang et al., Characterization of the mobilization determinants of pAN12, a small replicon from Rhodococcus erythropolis AN12. Plasmid 57, 71–81.
Shuttle_vector
Mammalian protein found in humans
to assist in a cell's immune pathway. Evidence shows elimination of HCV replicon, Lymphocytic choriomeningitis LCMV, and polyomavirus. ADAR1 is proviral
ADAR
RNA family
PMC 96696. PMID 11726689. Balsiger, S; Ragaz C; Baron C; Narberhaus F (2004). "Replicon-Specific Regulation of Small Heat Shock Genes in Agrobacterium tumefaciens"
Repression of heat shock gene expression (ROSE) element
Repression_of_heat_shock_gene_expression_(ROSE)_element
Chemical compound
Clark J, Hollecker L, Lostia S, et al. (2006). "Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific
PSI-6130
Realm of viruses
characteristics of ribozyvirians are similar to viroids, virusoids, and other replicons, such as genome structure, RNA transcription by means of a host DNA-directed
Ribozyviria
Partial viruses engineered for study
native viral structural proteins envelope (E), and pre-membrane/membrane (prM/M) in a lipid envelope, capsid protein, and a reporter RNA replicon genome.
Reporter_virus_particles
German virologist and university teacher
Bartenschlager CV, Robert Koch Foundation Foundation, Lasker. "Hepatitis C replicon system and drug development | The Lasker Foundation". The Lasker Foundation
Ralf_Bartenschlager
the packaging substrate is a newly displaced ssDNA molecule. Many small replicons that have circular genomes, such as many ssDNA viruses and plasmids, replicate
Rolling_hairpin_replication
Circular plasmid used in creation of transgenic plants
large in size, ranging from 100kbp to 2Mbp. They are also often termed replicons, as their replication begins at a single site. Members of this family
Ti_plasmid
Medication used to treat hepatitis C
and less than 22% of HCV cases respectively). Multiple mutations of HCV replicons are necessary to cause a significant effect in resistance due to multiple
Ledipasvir/sofosbuvir
Antiviral drug
hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors toward improved replicon cell activities: benzimidazole and structurally related compounds bearing
JTK-109
Chemical compound
cross-genotypic anti-norovirus activity and clears cells from the norovirus replicon". Antimicrobial Agents and Chemotherapy. 58 (8): 4675–81. doi:10.1128/AAC
Rupintrivir
redox - redox reaction - redox system - reflux - replication origin - replicon - repressor - repressor protein - respiration (physiology) - restriction
Index of biochemistry articles
Index_of_biochemistry_articles
Genus of archaea
into three circular replicons. More specifically, it is divided into one large chromosome with 2,014,239 bp and two small replicons pNRC100 (191,346 bp)
Halobacterium
Enzyme that catalyzes movement of transposable elements
encoding trimethoprim and streptomycin resistances from R483 to other replicons". Journal of Bacteriology. 125 (3): 800–810. doi:10.1128/JB.125.3.800-810
Transposase
Antibiotic resistance caused by a plasmid
Enterobacteriaceae, 28 different plasmid types can be identified by PCR-based replicon typing (PBRT).The plasmids that have been frequently reported [IncF, IncI
Plasmid-mediated_resistance
Type of virus that infects the domain of unicellular, prokaryotic organisms or Archaea
Archaeal viruses also appear to share many genes with non-viral selfish replicons such as plasmids and transposons. Many aspects of the life cycle of archaeal
Archaeal_virus
Species of bacteria
the type strain DSM 2944 shows its DNA is organised into four circular replicons, made up of two chromosomes and two megaplasmids. It has a relatively
Paracoccus_pantotrophus
Extremophile organism that tolerates high concentrations of dissolved heavy metals
insight into the heavy metal resistome of sinorhizobial extrachromosomal replicons". FEMS Microbiology Ecology. 93 (1) fiw215. doi:10.1093/femsec/fiw215
Metallotolerant
Genus of archaea
(NCBI). The genome of Natronomonas pharaonis consists of three circular replicons, the chromosome which is 2,595,221 bp in length, a typical haloarchaeal
Natronomonas
Genus of viruses
Chen, X (2016). "Identification, Characterization, and Application of the Replicon Region of the Halophilic Temperate Sphaerolipovirus SNJ1". Journal of Bacteriology
Yingchengvirus
REPLICON
REPLICON
REPLICON
REPLICON
Boy/Male
Assamese, Hindu, Indian
Blue
Female
English
Short form of English Elizabeth, BETH means "God is my oath."Â
Surname or Lastname
Americanized form of North German, Norwegian, and Danish Brodersen, or Jewish Broderson.English
Americanized form of North German, Norwegian, and Danish Brodersen, or Jewish Broderson.English : perhaps a variant of Brotherton.
Surname or Lastname
English
English : variant of Cowey.
Boy/Male
Hindu, Indian
A Sweet Little Angel; Dynamic Personality
Boy/Male
Indian, Punjabi, Sikh
Imbued with Cooling Peace
Girl/Female
Tamil
Its Hindi form is derived from a Sanskrit expression meaning star
Boy/Male
British, English
Form of Tilla
Girl/Female
Muslim
Intelligent
Boy/Male
Bengali, Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Tamil, Telugu
Lord Shiva
REPLICON
REPLICON
REPLICON
REPLICON
REPLICON