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RANGAP

  • RanGAP
  • RanGAP is a protein involved in the transport of other proteins from the cytosol to the nucleus in eukaryotic cells. In model species such as the yeast

    RanGAP

    RanGAP

  • WPP domain
  • Protein domain

    amino acid residues long. The domain is known to direct RanGAP to the nuclear envelope. Non-RanGAP nuclear envelope proteins are also known to encode WPP

    WPP domain

    WPP_domain

  • Ran (protein)
  • GTPase functioning in nuclear transport

    GTPase-activity is activated through interaction with Ran GTPase activating protein (RanGAP), facilitated by complex formation with Ran-binding protein (RanBP). GTPase-activation

    Ran (protein)

    Ran (protein)

    Ran_(protein)

  • RANBP1
  • Protein-coding gene in the species Homo sapiens

    Characterization of the Ran-RanBP1-RanGAP System: Are RanBP Proteins and the Acidic Tail of RanGAP Required for the Ran-RanGAP GTPase Reaction?". Mol. Cell

    RANBP1

    RANBP1

    RANBP1

  • Intragenomic conflict
  • Differential transmission of genes residing in the same genome

    main drive locus, a truncated tandem duplication of the gene RanGAP on chromosome 2L (Sd-RanGAP) targets a repetitive array of satellite DNA on chromosome

    Intragenomic conflict

    Intragenomic_conflict

  • Importin
  • Protein family

    still bound to Ran-GTP. Once in the cytoplasm, Ran-GTP is hydrolysed by RanGAP, forming Ran-GDP, and releasing the two importins for further activity.

    Importin

    Importin

  • XPO5
  • transporting pre-miRNA into the cytoplasm in the process. Once in the cytoplasm, RanGAP hydrolyzes GTP to GDP, causing a conformational change that releases the

    XPO5

    XPO5

    XPO5

  • LRRC73
  • Human gene

    Description E-value 444072 28..254 COG5238, RNA1, Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure

    LRRC73

    LRRC73

    LRRC73

  • RANBP2
  • Protein-coding gene in the species Homo sapiens

    SP100. Another target for SUMOylation is RanGAP which is the GTPase activating protein for Ran. SUMO-RanGAP interacts with a domain near the carboxyl

    RANBP2

    RANBP2

    RANBP2

  • SENP1
  • Protein-coding gene in humans

    SENP1 mutant (C603S) in complex with SUMO-1 2iy0: SENP1 (MUTANT) SUMO1 RANGAP 2iy1: SENP1 (MUTANT) FULL LENGTH SUMO1 2iyc: SENP1 NATIVE STRUCTURE 2iyd:

    SENP1

    SENP1

    SENP1

  • GARNL1
  • Protein-coding gene in the species Homo sapiens

    PMC 2755882. PMID 19520869. "Entrez Gene: GARNL1 GTPase activating Rap/RanGAP domain-like 1". Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction

    GARNL1

    GARNL1

    GARNL1

  • SUMO1
  • Protein-coding gene in the species Homo sapiens

    of human Senp2 in complex with RanGAP1-SUMO-1 2iy0: SENP1 (MUTANT) SUMO1 RANGAP 2iy1: SENP1 (MUTANT) FULL LENGTH SUMO1 2pe6: Non-covalent complex between

    SUMO1

    SUMO1

    SUMO1

  • RANGAP1
  • Protein-coding gene in the species Homo sapiens

    3UIN, 3UIO, 3UIP, 5D2M, 2IO2, 2IO3 Identifiers Aliases RANGAP1, Fug1, RANGAP, SD, Ran GTPase activating protein 1 External IDs OMIM: 602362; MGI: 103071;

    RANGAP1

    RANGAP1

    RANGAP1

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Online names & meanings

  • Dibendu
  • Boy/Male

    Hindu

    Dibendu

  • Madan Gopal
  • Boy/Male

    Hindu

    Madan Gopal

    Lord Krishna

  • Afsheen
  • Girl/Female

    Indian

    Afsheen

    Shining star

  • Ranish
  • Boy/Male

    Hindu, Indian

    Ranish

    Lord Shiva

  • Hutchens
  • Surname or Lastname

    English

    Hutchens

    English : patronymic from the medieval personal name Huchin, a pet form of Hugh (see Hutcheon).

  • Madhuk | மதுக
  • Boy/Male

    Tamil

    Madhuk | மதுக

    A honeybee

  • Ã…SLÖG
  • Female

    Swedish

    ÅSLÖG

    Swedish form of Old Norse Áslaug, ÅSLÖG means "God-betrothed woman."

  • Lssse
  • Girl/Female

    English

    Lssse

    Girl.

  • Body
  • Surname or Lastname

    English

    Body

    English : nickname from Middle English body, Old English bodig ‘body’, ‘trunk’, presumably denoting a corpulent person. In Middle English the word was also used in the sense ‘individual’, ‘person’.English : occupational name for a messenger, Middle English bode (Old English boda; compare Bothe), with the spelling altered to preserve a disyllabic pronunciation. This development can be clearly traced in Sussex.French : variant of Bodin.Hungarian (Bódy) : variant of Bódi (see Bodi).

  • Cousens
  • Surname or Lastname

    English

    Cousens

    English : patronymic form of Cousin.

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