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SUMO1

  • SUMO1
  • Protein-coding gene in the species Homo sapiens

    ubiquitin-related modifier 1 is a protein that in humans is encoded by the SUMO1 gene. This gene encodes a protein that is a member of the SUMO (small ubiquitin-like

    SUMO1

    SUMO1

    SUMO1

  • SUMO protein
  • Family of proteins which attach to other proteins to modify them

    the formation of SUMO chains. The structure of human SUMO1 is depicted on the right. It shows SUMO1 as a globular protein with both ends of the amino acid

    SUMO protein

    SUMO protein

    SUMO_protein

  • Cleft lip and cleft palate
  • Birth defect of the palate and upper lip

    1q OFC7 600644) PVRL1 11q OFC8 129400 TP63 3q27 OFC9 610361 ? 13q33.1-q34 OFC10 601912 SUMO1 2q32.2-q33 OFC11 600625 BMP4 14q22 OFC12 612858 ? 8q24.3

    Cleft lip and cleft palate

    Cleft lip and cleft palate

    Cleft_lip_and_cleft_palate

  • SAE1
  • Protein-coding gene in the species Homo sapiens

    1016/S0014-5793(99)00367-1. PMID 10217437. S2CID 7756078. "Entrez Gene: SAE1 SUMO1 activating enzyme subunit 1". Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa

    SAE1

    SAE1

    SAE1

  • UBA2
  • Protein-coding gene in the species Homo sapiens

    modification of proteins by the addition of the small protein SUMO (see SUMO1), or sumoylation, regulates protein structure and intracellular localization

    UBA2

    UBA2

    UBA2

  • SENP6
  • Protein-coding gene in the species Homo sapiens

    is encoded by the SENP6 gene. Ubiquitin-like molecules (UBLs), such as SUMO1, are structurally related to ubiquitin and can be ligated to target proteins

    SENP6

    SENP6

    SENP6

  • Chromosome 6
  • Human chromosome

    SCZD5: schizophrenia disorder 5 SEN6: senescence (cellular)-related 6 SENP6: SUMO1/sentrin specific peptidase 6 (6q14.1) SERAC1: serine active site containing

    Chromosome 6

    Chromosome 6

    Chromosome_6

  • SENP1
  • Protein-coding gene in humans

    692–703. doi:10.1074/jbc.M306195200. PMID 14563852. "Entrez Gene: SENP1 SUMO1/sentrin specific peptidase 1". Xu Z, Chau SF, Lam KH, Chan HY, Ng TB, Au

    SENP1

    SENP1

    SENP1

  • SENP2
  • Protein-coding gene in the species Homo sapiens

    Sentrin-specific protease 2 is an enzyme that in humans is encoded by the SENP2 gene. SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently

    SENP2

    SENP2

    SENP2

  • AtSCE1
  • Enzyme

    happen in A. thaliana as well. In response to heat stress, within 30 minutes SUMO1/2 conjugates had a 6-fold increase that was faster than even heat shock

    AtSCE1

    AtSCE1

  • GLUT4
  • Transport protein

    physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1". The Journal of Biological Chemistry. 277 (22): 19783–19791. doi:10.1074/jbc

    GLUT4

    GLUT4

    GLUT4

  • P53
  • Mammalian protein found in humans

    PTTG1, RAD51, RCHY1, RELA, Reprimo[citation needed] RPA1, RPL11, S100B, SUMO1, SMARCA4, SMARCB1, SMN1, STAT3, TBP, TFAP2A, TFDP1, TIGAR, TOP1, TOP2A,

    P53

    P53

    P53

  • Abgent
  • Global biotechnology company based in San Diego, California

    Ting, Leroy F. Liu, and Jaulang Hwang. Assembly of a Polymeric Chain of SUMO1 on Human Topoisomerase I in Vitro J. Biol. Chem., Mar 2006; 281: 8264 -

    Abgent

    Abgent

  • Ubiquitin
  • Regulatory protein found in most eukaryotic tissues

    LOC391257; MIDN; NEDD8; OASL; PARK2; RAD23A; RAD23B; RPS27A; SACS; 8U SF3A1; SUMO1; SUMO2; SUMO3; SUMO4; TMUB1; TMUB2; UBA52; UBB; UBC; UBD; UBFD1; UBL4A;

    Ubiquitin

    Ubiquitin

    Ubiquitin

  • SENP3
  • Protein-coding gene in humans

    SUMO1/sentrin/SMT3 specific peptidase 3, also known as SENP3, is a protein which in humans is encoded by the SENP3 gene. SENP3 together with SENP5, belongs

    SENP3

    SENP3

    SENP3

  • Upper ontology
  • Ontology applicable across domains of knowledge

    scope. ISO 15926-2:2003 SUMO 2000 v1.1 - ontologyportal.org/SUMOhistory/SUMO1.1.txt IEEE working group P1600.1 For research and applications in search

    Upper ontology

    Upper_ontology

  • Transcription factor Sp1
  • Protein-coding gene in the species Homo sapiens

    MEF2C, MEF2D, MSX1, Myogenin, POU2F1, PPP1R13L, PSMC5, PML, RELA, SMAD3, SUMO1, SF1, TAL1, UBC. WRN, DDX3X GRCh38: Ensembl release 89: ENSG00000185591

    Transcription factor Sp1

    Transcription factor Sp1

    Transcription_factor_Sp1

  • DNMT3B
  • Protein-coding gene in the species Homo sapiens

    has been shown to interact with: CBX5, DNMT1, DNMT3A, KIF4A, NCAPG, SMC2, SUMO1 and UBE2I. GRCh38: Ensembl release 89: ENSG00000088305 – Ensembl, May 2017

    DNMT3B

    DNMT3B

    DNMT3B

  • SENP7
  • Protein-coding gene in the species Homo sapiens

    doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. "Entrez Gene: SENP7 SUMO1/sentrin specific peptidase 7". Mikolajczyk J, Drag M, Békés M, Cao JT, Ronai

    SENP7

    SENP7

    SENP7

  • Microphthalmia-associated transcription factor
  • Mammalian protein found in humans

    associates with MITF. Although hUBC9 is known to act preferentially with SENTRIN/SUMO1, an in vitro analysis demonstrated greater actual association with MITF

    Microphthalmia-associated transcription factor

    Microphthalmia-associated transcription factor

    Microphthalmia-associated_transcription_factor

  • TANGO2
  • Protein-coding gene in the species Homo sapiens

    interact with NFKB1, RELA, RELB, BTRC, RPS27A, BCL3, MAP3K8, NFKBIA, SIN3A, SUMO1, Tat. Mutations in the TANGO2 gene may cause defects in mitochondrial β-oxidation

    TANGO2

    TANGO2

    TANGO2

  • Housekeeping gene
  • Gene which maintains basic cellular functions

    ER SSR3 Translocon-associated protein TRAPG. Protein translocation in ER SUMO1 Protein targeting SUMO3 Protein targeting HSPA4 HSPA5 HSPA8 HSPA9 HSPA14

    Housekeeping gene

    Housekeeping_gene

  • Tumor necrosis factor receptor 1
  • Membrane receptor protein found in humans

    interact with: BAG4, CASP10, FADD, IKK2, JAK1, JAK2, PIP4K2B, PSMD2, RIPK1, SUMO1, TRADD TRAF2, TRPC4AP, TNF, and UBE2I. Cluster of differentiation TNF receptor

    Tumor necrosis factor receptor 1

    Tumor necrosis factor receptor 1

    Tumor_necrosis_factor_receptor_1

  • List of human protein-coding genes 8
  • Q6IMI4 16091 SUMF1 HGNC:20376; Q8NBK3 16092 SUMF2 HGNC:20415; Q8NBJ7 16093 SUMO1 HGNC:12502; P63165 16094 SUMO2 HGNC:11125; P61956 16095 SUMO3 HGNC:11124;

    List of human protein-coding genes 8

    List_of_human_protein-coding_genes_8

  • UBE2I
  • Protein-coding gene in the species Homo sapiens

    MAP3K1 and MITF, P53, PIAS1, PIAS2, RAD51, RANBP2, RANGAP1, SAE2, SALL1, SUMO1, TCF3, TNFRSF1A, TOP1, and WT1. GRCh38: Ensembl release 89: ENSG00000103275

    UBE2I

    UBE2I

    UBE2I

  • GARNL1
  • Protein-coding gene in the species Homo sapiens

    PMID 14702039. Swaminathan S, Kiendl F, Körner R, et al. (2004). "RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2

    GARNL1

    GARNL1

    GARNL1

  • NFKB2
  • Protein-coding gene in the species Homo sapiens

    C200151200. PMID 11994270. Vatsyayan J, Qing G, Xiao G, Hu J (Sep 2008). "SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation

    NFKB2

    NFKB2

    NFKB2

  • Thymine-DNA glycosylase
  • Protein-coding gene in the species Homo sapiens

    v t e PDB gallery 1wyw: Crystal Structure of SUMO1-conjugated thymine DNA glycosylase 2d07: Crystal Structure of SUMO-3-modified Thymine-DNA Glycosylase

    Thymine-DNA glycosylase

    Thymine-DNA glycosylase

    Thymine-DNA_glycosylase

  • PRKCQ
  • Protein-coding gene in the species Homo sapiens

    As a result of co-stimulation by CD28 and TCR, PKC-θ is sumoylated by SUMO1 predominantly on the sites Lys325 and Lys506. Sumoylation is important because

    PRKCQ

    PRKCQ

    PRKCQ

  • STC1
  • Glycoprotein, a homologue of a hormone stanniocalcin

    is responsible to establish the interaction with its partners, including SUMO1. Low-resolution studies shows that STC1 is an anti-parallel homodimer in

    STC1

    STC1

    STC1

  • Carnitine O-acetyltransferase
  • Enzyme

    diabetes and other diseases. CRAT is known to interact with NEDD8, PEX5, SUMO1. GRCm38: Ensembl release 89: ENSMUSG00000026853 – Ensembl, May 2017 "Human

    Carnitine O-acetyltransferase

    Carnitine O-acetyltransferase

    Carnitine_O-acetyltransferase

  • RANBP2
  • Protein-coding gene in the species Homo sapiens

    RanBP2 is the E2 enzyme UBC9. RanBP2 strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. Another target for SUMOylation is RanGAP which

    RANBP2

    RANBP2

    RANBP2

  • RANGAP1
  • Protein-coding gene in the species Homo sapiens

    of human Senp2 in complex with RanGAP1-SUMO-1 2io3: Crystal structure of human Senp2 in complex with RanGAP1-SUMO-2 2iy0: SENP1 (MUTANT) SUMO1 RANGAP

    RANGAP1

    RANGAP1

    RANGAP1

  • BTRC (gene)
  • Protein-coding gene in the species Homo sapiens

    C200151200. PMID 11994270. Vatsyayan J, Qing G, Xiao G, Hu J (September 2008). "SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation

    BTRC (gene)

    BTRC (gene)

    BTRC_(gene)

  • FBXW11
  • Protein-coding gene in the species Homo sapiens

    C200151200. PMID 11994270. Vatsyayan J, Qing G, Xiao G, Hu J (Sep 2008). "SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation

    FBXW11

    FBXW11

    FBXW11

  • FaceBase
  • NIH-supported American dentistry initiative

    MMP3, MSX1, MSX2 (Msh homeobox 2), MSX3, PAX7, PDGFC, PTCH1, SATB2, SOX9, SUMO1 (Small ubiquitin-related modifier 1), TBX22, TCOF (Treacle protein), TFAP2A

    FaceBase

    FaceBase

  • SUMO2
  • Protein-coding gene in the species Homo sapiens

    experiment conducted to moderate hypothermia, small ubiquitin-like modifier (SUMO1-3) conjugation was significantly activated in the brain. The effects of

    SUMO2

    SUMO2

    SUMO2

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Online names & meanings

  • Samirah
  • Girl/Female

    Muslim/Islamic

    Samirah

    Entertaining female companion

  • Tejowathi | தேஜோவதீ
  • Girl/Female

    Tamil

    Tejowathi | தேஜோவதீ

    Another name for Goddess Durga

  • Ritusha
  • Girl/Female

    Indian

    Ritusha

    Season

  • PAPILLION
  • Male

    French

    PAPILLION

    French name derived from the word papillon, PAPILLION means "butterfly."

  • Daanaa
  • Boy/Male

    Arabic

    Daanaa

    Wise; Intelligent

  • Abu Ayyub |
  • Boy/Male

    Muslim

    Abu Ayyub |

    A well-known sahabi

  • Kelp
  • Surname or Lastname

    English (Norfolk)

    Kelp

    English (Norfolk) : possibly a metonymic occupational name for someone who collected and burnt kelp (seaweed) for use in soap and glass making, Middle English culp(e).

  • Rick
  • Boy/Male

    American, Anglo, Australian, British, Chinese, Christian, Dutch, English, French, German, Indian, Norse, Scandinavian, Swedish

    Rick

    Rich and Powerful Ruler; War Leader; Dominant Ruler; People's Ruler; Power of the Wolf; Brother; All-ruler; Strong Power; Hardy Power; Powerful and Brave Ruler

  • Gururaj
  • Boy/Male

    Hindu, Indian, Marathi, Tamil

    Gururaj

    Lord of the Spiritual Teachers; Master of Teacher

  • Zeresh
  • Biblical

    Zeresh

    misery; strange; dispersed inheritance

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SUMO1

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