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Analytical chemistry technique
Quantitative proteomics is an analytical chemistry technique for determining the amount of proteins in a sample. The methods for protein identification
Quantitative_proteomics
Large-scale study of proteins
Proteomics is the large-scale study of proteins. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics
Proteomics
Type of mass spectrometry
spectrometer, this is called "bottom-up proteomics". Shotgun proteomics is a variant of bottom up proteomics in which proteins in a mixture are digested
Tandem_mass_spectrometry
Medical diagnostic technique
milestones in advances have been: Single-cell proteomics Techniques of SCOPE-MS and prioritized Single Cell ProtEomics (pSCoPE) allow for deep analysis of individual
Proteomic_profiling
Laboratory technique for quantitative proteomics
non-radioactive isotopic labeling. It is a popular method for quantitative proteomics. Two populations of cells are cultivated in cell culture. One of
Stable isotope labeling by amino acids in cell culture
Stable_isotope_labeling_by_amino_acids_in_cell_culture
Analytical technique to study proteins
Activity-based proteomics, or activity-based protein profiling (ABPP) is a chemoproteomic strategy that employs modular probes to directly assess the functional
Activity-based_proteomics
Genome regions affecting protein levels
analyses are only possible because of the growing field of proteomics. Scientists who study proteomics use techniques like mass spectrometry and affinity-based
Protein quantitative trait loci
Protein_quantitative_trait_loci
American biotechnology company
000-Sample Proteomics Study". Clinical Lab Products. Retrieved 2025-10-29. Wolski, Chris (2025-06-03). "Proteograph Platform Enables 20,000-Sample Proteomics Study"
Seer,_Inc.
Sensitivity, and Specificity in Data-dependent Quantitative Label-free Shotgun Proteomics". Molecular & Cellular Proteomics. 15 (2): 657–668. doi:10.1074/mcp.M115
List of mass spectrometry software
List_of_mass_spectrometry_software
Juvenile form of distinct animals before metamorphosis
Wong, Yue Him; Ravasi, Timothy; Qian, Pei-Yuan (2014-02-13). "Quantitative Proteomics Study of Larval Settlement in the Barnacle Balanus amphitrite"
Larva
German-American molecular biologist
associate professor at the New York University. Her research considers quantitative proteomics. She is particularly interested in protein expression patterns
Christine_Vogel
Chemical tagging technique used in quantitative proteomics
Isobaric labeling is a mass spectrometry strategy used in quantitative proteomics. Peptides or proteins are labeled with chemical groups that have nominally
Isobaric_labeling
absolute quantitation (iTRAQ) is an isobaric labeling method used in quantitative proteomics by tandem mass spectrometry to determine the amount of proteins
Isobaric tag for relative and absolute quantitation
Isobaric_tag_for_relative_and_absolute_quantitation
Tandem mass spectrometry method
for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics". Molecular & Cellular Proteomics. 11 (11): 1475–1488. doi:10.1074/mcp.O112
Selected_reaction_monitoring
Rare isotope of carbon
non-radioactive. In addition, 13C is used to quantify proteins (quantitative proteomics). One important application is in stable isotope labeling by amino
Carbon-13
Public database of protein mass spectrometry data in Europe
The PRIDE (PRoteomics IDEntifications database) is a public data repository of mass spectrometry-based proteomics data, and is maintained by the European
Proteomics Identifications Database
Proteomics_Identifications_Database
Swiss biologist (born 1954)
spectrometry and proteomics data, and he is one of the inventors of the Isotope-Coded Affinity Tag (ICAT) technique for quantitative proteomics, a technique
Ruedi_Aebersold
(2007). "A Metal-coded Affinity Tag Approach to Quantitative Proteomics". Molecular & Cellular Proteomics. 6 (11): 1907–1916. doi:10.1074/mcp.M700152-MCP200
Metal-coded_affinity_tag
Chemist
in proteomics and the study of Alzheimer's disease, sepsis, and aging. She has developed a novel multiplexing strategy for quantitative proteomics called
Renã_A._S._Robinson
Venomous species of elapid snake
SI; Arapidi, GP; Starkov, VG; Hoang, AN; et al. (December 2015). "Quantitative proteomic analysis of Vietnamese krait venoms: Neurotoxins are the major components
Many-banded_krait
protein identification using mass spectrometry (MS; Bottom Up proteomics). Top-down proteomics using mass spectrometry interrogates protein structure through
Top-down_proteomics
Protein complexes which degrade ubiquitin-tagged proteins by proteolysis
Robert J, Rush J, Hochstrasser M, Finley D, Peng J (April 2009). "Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal
Proteasome
Subfield
proteomics measures the localization and abundance of proteins at the subcellular level across a tissue. Immunohistochemistry-based spatial proteomic
Spatial_biology
Post-translational carbohydrate modification of proteins
"Probing the Dynamics of O-GlcNAc Glycosylation in the Brain Using Quantitative Proteomics" (PDF). Nature Chemical Biology. 3 (6): 339–48. doi:10.1038/nchembio881
O-GlcNAc
Topics referred to by the same term
reaction monitoring, a method for targeted, mass spectrometry-based quantitative proteomics Selective receptor modulator, a type of drug Specified risk material
SRM
Ultrafine particles of silver between 1 nm and 100 nm in size
the cellular response triggered by silver nanoparticles using quantitative proteomics". ACS Nano. 8 (3): 2161–2175. Bibcode:2014ACSNa...8.2161V. doi:10
Silver_nanoparticle
affinity tag (ICAT) is an in-vitro isotopic labeling method used for quantitative proteomics by mass spectrometry that uses chemical labeling reagents. These
Isotope-coded_affinity_tag
Quantification of biomolecules via mass spectrometry without using chemical labels
method by MS/MS TIC compared to SILAC and spectral counting in a proteomics screen". Proteomics. 8 (5): 994–9. doi:10.1002/pmic.200700426. PMID 18324724. Bridges
Label-free_quantification
Type of mass spectrometry that uses an inductively coupled plasma to ionize the sample
(2007). "A metal-coded affinity tag approach to quantitative proteomics". Molecular & Cellular Proteomics. 6 (11): 1907–1916. doi:10.1074/mcp.M700152-MCP200
Inductively coupled plasma mass spectrometry
Inductively_coupled_plasma_mass_spectrometry
Mathematical ratio used in analysis of radioactive materials
medium containing 15N as the only source of nitrogen, e.g., in quantitative proteomics such as SILAC. Nitrogen-15 is extensively used to trace mineral
Isotopic_signature
Techniques used to study protein–small molecule interactions
chromatography-tandem mass spectrometry (LC-MS/MS or LC-MS) based quantitative proteomics, which allows for the near complete identification and relative
Chemoproteomics
Form of gel electrophoresis used in analyzing proteins
the transfer to the SDS-PAGE gel. See Isoelectric focusing In quantitative proteomics, these tools primarily analyze bio-markers by quantifying individual
Two-dimensional gel electrophoresis
Two-dimensional_gel_electrophoresis
Genus of bacteria
Pandhal, Jagroop; Wright, Phillip C.; Biggs, Catherine A. (2007). "A quantitative proteomic analysis of light adaptation in a globally significant marine cyanobacterium
Prochlorococcus
American chronobiologist and photobiologist
Kettenbach, A.N.; Loros, J.J.; Gerber, S.A.; Dunlap, J.C. (2009). "Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation
Jay_Dunlap
Activation or suppression of the immune system to treat disease
MH, Huang TC, Hsu CL, Tsai SR, Lee SC, et al. (February 2015). "Quantitative proteomics reveals middle infrared radiation-interfered networks in breast
Immunotherapy
Analytical technique
nitrogen. In addition, nitrogen-15 is used to label proteins in quantitative proteomics (e.g. SILAC). 15N NMR has complications not encountered in 1H and
Nitrogen-15 nuclear magnetic resonance spectroscopy
Nitrogen-15_nuclear_magnetic_resonance_spectroscopy
Medical model that tailors medical practices to the individual patient
including health and disease, so proteomics is helpful in early diagnosis. In the case of respiratory disease, proteomics analyzes several biological samples
Personalized_medicine
Class of enzymes
protein phosphorylation is a cell-wide regulatory mechanism, recent quantitative proteomics studies have shown that phosphorylation preferentially targets
Protein_phosphatase
Proteomics, 9, 1920-1936 Wagner W., Ajuh P., Löwer J., Wessler S. (2010) Cell. Commun. Signal. 8, 28 "Dundee Cell Proteomics". Dundee Cell Proteomics
Dundee_Cell_Products
Laboratory technique
Antony P. (2015-11-01). "Protein Neighbors and Proximity Proteomics". Molecular & Cellular Proteomics. 14 (11): 2848–2856. doi:10.1074/mcp.R115.052902. ISSN 1535-9476
Proximity_labeling
Study of the separation, identification, and quantification of matter
sequencing and related research in genetic fingerprinting and DNA microarray; proteomics, the analysis of protein concentrations and modifications, especially
Analytical_chemistry
Biochemical modification of drugs or foreign compounds by living organisms
AT, Lignet F, Cutler P, Parrott N (August 2015). "The role of quantitative ADME proteomics to support construction of physiologically based pharmacokinetic
Drug_metabolism
Suffix in biology
emerging field of biological research at the intersection of proteomics and genomics. Proteomics data used for gene annotations. Structural genomics: Study
Omics
German physicist and biochemist (born 1959)
isotope labeling with amino acids in cell culture) is widely used in quantitative proteomics. PharmaFluidics, Member of the Advisory Board (since 2019) 1991:
Matthias_Mann
Terminal amine isotopic labeling of substrates (TAILS) is a method in quantitative proteomics that identifies the protein content of samples based on N-terminal
Terminal amine isotopic labeling of substrates
Terminal_amine_isotopic_labeling_of_substrates
Enzyme
(October 2009). "Receptor tyrosine kinase signaling: a view from quantitative proteomics". Molecular BioSystems. 5 (10): 1112–1121. doi:10.1039/b909534a
Tyrosine_kinase
Sendai virus, virus of rodents
Lauterbach H, Fancke B, Selbach M, Tschopp J, et al. (February 2010). "Quantitative proteomics reveals subset-specific viral recognition in dendritic cells".
Murine_respirovirus
Communication within or between species
Social network architecture of human immune cells unveiled by quantitative proteomics. Nat Immunol. 18(5):583-593. Tembrock, Günter (1971). Biokommunikation:
Biocommunication_(science)
Database of biological pathways
can in fact be any numeric value, e.g. differential expression, quantitative proteomics, GWAS scores. The expression data is represented as colouring of
Reactome
Indian scientist, medical researcher
(February 2010). "Quantitative proteomic profiling of prostate cancer reveals a role for miR-128 in prostate cancer". Mol. Cell. Proteomics. 9 (2): 298–312
Arul_Chinnaiyan
Software for analysis of mass spectrometric data
et al. (2017). "The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics". Mass Spectrometry Reviews. 39 (3): 229–244. doi:10.1002/mas
Skyline_(software)
Application of mass spectrometry
Slavov, Nikolai (January 2022). "Scaling Up Single-Cell Proteomics". Molecular & Cellular Proteomics. 21 (1) 100179. doi:10.1016/j.mcpro.2021.100179. PMC 8683604
Protein_mass_spectrometry
Class of green algae
Mechanism in Halotolerant Algae Dunaliella salina Revealed by Quantitative Proteomics and Phosphoproteomics". Frontiers in Plant Science. 8 810. Bibcode:2017FrPS
Chlorophyceae
One of the five main histone proteins
Bhanu NV, LeRoy G, Arnaudo AM, Garcia BA (2015). "Multi-faceted quantitative proteomics analysis of histone H2B isoforms and their modifications". Epigenetics
Histone_H2B
Canadian cell biologist
Canadian National Proteomics Network Prix D’Excellence Award for Outstanding Contribution and Leadership to the Canadian Proteomics Community (2010).
John_J._M._Bergeron
Biomolecule consisting of chains of amino acid residues
sets defines the field of proteomics, named by analogy to the related field of genomics. Key experimental techniques in proteomics include 2D electrophoresis
Protein
Protein-coding gene in the species Homo sapiens
Mizokami A, Morrissey C, Jarvi K, Diamandis EP (June 2013). "Quantitative proteomics reveals that enzymes of the ketogenic pathway are associated with
ACAT1
Chinese-born Wisconsin professor
Costello Award for Exemplary Achievements in Proteomics Isobaric tandem mass tags for quantitative proteomics and peptidomics (2012) US 9388132 B2 Mass defect-based
Lingjun_Li
Scientist and physician (b. 1975)
Hanno (2009-09-01). "Urine proteomics for profiling of human disease using high accuracy mass spectrometry". Proteomics. Clinical Applications. 3 (9):
Alex_Kentsis
Microsoft Windows, MacOS and Linux. OpenMS has tools for analysis of proteomics data, providing algorithms for signal processing, feature finding (including
OpenMS
Topics referred to by the same term
Coalition Against Terrorism Isotope-coded affinity tag, a method for quantitative proteomics A radio station from Catalunya Ràdio. Another name for the protein
ICAT
Sub-discipline of biology
by Positional Proteomics. ACS Chem. Biol. 10, 1754-1764 (2015). Eckhard U., Marino G., Butler G. S., Overall C. M. Positional proteomics in the era of
Degradomics
American chemist
Pankow, Sandra; Bamberger, Tom Casimir; Yates, John R. (2023), Quantitative structural proteomics in living cells by covalent protein painting, Methods in Enzymology
John_R._Yates
Analytical technique used in molecular biology
(November 2010). "Subcellular fractionation methods and strategies for proteomics". Proteomics. 10 (22): 3935–3956. doi:10.1002/pmic.201000289. PMID 21080488
Western_blot
Transcription factor for converting Naive T cells to TFH
X, Shen Y, Liu M, Bi C, Jiang C, Iqbal J, et al. (July 2012). "Quantitative proteomics reveals that miR-155 regulates the PI3K-AKT pathway in diffuse
BCL6
Dutch chemist
access to proteomics infrastructures in the Netherlands and in Europe. Since 2003 Heck is scientific director of the Netherlands Proteomics Centre. From
Albert_J._R._Heck
biotinylation by birA* has facilitated the first proteomics-based studies of the cadherin adhesome. While proteomic methods identified many novel proteins that
Adhesome
Protein family
Baker CL, Kettenbach AN, Loros JJ, Gerber SA, Dunlap JC (2009). "Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation
Frequency_(gene)
Interstitial cells
data show that TCs are completely different from FBs, using a quantitative proteomics approach, suggesting that TCs might play specific roles in mechanical
Telocyte
Set of proteins that can be expressed by a genome, cell, tissue, or organism
(December 2007). "Viral proteomics: global evaluation of viruses and their interaction with the host". Expert Review of Proteomics. 4 (6): 815–829. doi:10
Proteome
Form of protein microarray
"Dual-color proteomic profiling of complex samples with a microarray of 810 cancer-related antibodies". Molecular & Cellular Proteomics. 9 (6): 1271–80
Antibody_microarray
Scientist researching clinical proteomics
Organization. She was a technical briefs editor at Proteomics. She served on the editorial board of Proteomics: clinical application and Journal of Physiology
Jennifer_Van_Eyk
Chinese biochemist
application of quantitative proteomics, and regulation mechanism of protein dynamic behavior. Her team developed novel methods for proteomics research including
Zeng_Rong
Computational and mathematical modeling of complex biological systems
multiomics (transcriptomics, metabolomics, proteomics, etc) and high-throughput techniques are used to collect quantitative data for the construction and validation
Systems_biology
a freely available, web-accessible database that provides quantitative genomic, proteomic as well metabolomic data on Escherichia coli. Escherichia coli
CyberCell
Protein-coding gene in the species Homo sapiens
"Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5". Proteomics. 11 (8): 1508–16
Heat shock protein 90kDa alpha (cytosolic), member A1
Heat_shock_protein_90kDa_alpha_(cytosolic),_member_A1
Human gene
of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative Proteomics". Cell. 143 (6): 951–965. doi:10.1016/j.cell.2010.11.017. ISSN 0092-8674
KLHL28
Protein-coding gene in the species Homo sapiens
Cui YQ, Liu XH, Li J, Yan MX, Liu L, He XH, Li JJ, Yao M (2013). "Quantitative proteomic analysis identifies CPNE3 as a novel metastasis-promoting gene in
Copine_3
Indian-American scientist
SR, Adams CM, Bhattacharya S (2016). Elucidating the “Gravome”: Quantitative Proteomic Profiling of the Response to Chronic Hypergravity in Drosophila
Sharmila_Bhattacharya
Proteins present in blood serum
protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics". Nat Commun. 7 10261. Bibcode:2016NatCo...710261M. doi:10
Plasma_protein
Italian biologist and academic
mass spectrometry-based proteomics, the large-scale analysis of thousands of proteins from cells and tissues. Whilst proteomics offers the potential for
Paola_Picotti
American chemist
Electron-transfer dissociation Proteomics Quantitative proteomics and Isobaric labeling 2018, Discovery in Proteomic Sciences Award from the Human Proteome
Joshua_Coon
Glycoprotein found in humans
Thangavelu M, Zhang L, Green KB, Nichols KK (July 2012). "iTRAQ quantitative proteomics in the analysis of tears in dry eye patients". Invest Ophthalmol
Lacritin
Substrates performing biochemical reactions
genetic variation, and explore gene function. Protein chips (also known as proteomics chips) are designed to detect and analyze proteins. These chips contain
Biochip
Protein-coding gene in the species Homo sapiens
interactome in SH-SY5Y human neuroblastoma cells: A label-free quantitative proteomics approach". Journal of Proteome Research. 12 (5): 2101–15. doi:10
TMEM33
Professor of Chromosome Dynamics at the University of Edinburgh
pathways using vertebrate conditional knockout cell lines and quantitative proteomics. ed.ac.uk (PhD thesis). University of Edinburgh. hdl:1842/8964
Bill_Earnshaw
American chemist
"Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics" (PDF). Nature Chemical Biology. 3 (6): 339–348. doi:10.1038/nchembio881
Linda_Hsieh-Wilson
Protein-coding gene in the species Homo sapiens
Rothwell C, Borawoski J, Jeffery DA, et al. (September 2015). "Quantitative Proteomic Verification of Membrane Proteins as Potential Therapeutic Targets
FGF19
Blue light photoreceptor in fungi
CL, Kettenbach AN, Loros JJ, Gerber SA, Dunlap JC (May 2009). "Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation
White_Collar-1
Database and analysis software for systems genetics
arrays, RNA-seq, epigenomic, proteomic, metabolomic, and metagenomic methods (molecular phenotypes) Standard quantitative phenotypes that are often parts
GeneNetwork
Chemical compound
PMID 21422471. Xiong, Lei; Wang, Yinsheng (5 February 2010). "Quantitative Proteomic Analysis Reveals the Perturbation of Multiple Cellular Pathways
Potassium_arsenite
of Canada. Her work on interaction proteomics, was awarded, alongside John Yates, the Discovery Award in Proteomics from the Human Proteome Organization
Anne-Claude_Gingras
(2009). "Isotope dilution strategies for absolute quantitative proteomics". Journal of Proteomics. 72 (5): 740–749. doi:10.1016/j.jprot.2009.03.007.
Stable isotope standards and capture by anti-peptide antibodies
Stable_isotope_standards_and_capture_by_anti-peptide_antibodies
Chemical compound
comprehensive proteomic analysis of totarol induced alterations in Bacillus subtilis by multipronged quantitative proteomics". Journal of Proteomics. 114: 247–262
Totarol
Protein-coding gene in the species Homo sapiens
(January 2009). "Temporal analysis of neural differentiation using quantitative proteomics". J. Proteome Res. 8 (3): 1315–26. doi:10.1021/pr8006667. PMC 2693473
SPTBN5
Bioinformatics method
enriched or depleted groups of genes. Transcriptomics technologies and proteomics results often identify thousands of genes, which are used for the analysis
Gene_set_enrichment_analysis
Gene
W, Zhang J, et al. (2020-04-22). "Bioinformatics combined with quantitative proteomics analyses and identification of potential biomarkers in cholangiocarcinoma"
FAM98C
Biologist who studies genes and genetic technologies and processes
Pharmacogenomics Molecular ecology Animal breeding Genomics Biotechnology Proteomics Microbial genetics Teaching Molecular diagnostics Sales and marketing
Geneticist
Species of bacterium
Luo, J; Zhou, Y; Xu, Y; Xu, P; Li, W; Tao, Y (4 January 2016). "Quantitative Proteomics Reveals Membrane Protein-Mediated Hypersaline Sensitivity and Adaptation
Nocardiopsis_xinjiangensis
Scientific discipline
work to improve proteomics through the development of enrichment strategies, chemical affinity tags, and new probes. Samples for proteomics often contain
Chemical_biology
QUANTITATIVE PROTEOMICS
QUANTITATIVE PROTEOMICS
QUANTITATIVE PROTEOMICS
QUANTITATIVE PROTEOMICS
Girl/Female
Hindu
Girl/Female
Assamese, Hindu, Indian, Kannada, Malayalam, Marathi, Tamil, Telugu
Celestial Damsel
Male
English
English surname of French origin, transferred to forename use, TROY means "from Troyes."
Boy/Male
Sikh
The feet of the Guru
Girl/Female
Irish
Dark-haired.
Female
Hebrew
(×ֲבִיגַיִל) Variant spelling of Hebrew Abigayil, AVIGAYIL means "father rejoices." In the bible, this is the name of the wife of King David.Â
Girl/Female
Hindu
Flowering, Blooming, Flower
Boy/Male
Hindu
Calm, Tranquil, Stedy, Quiet
Boy/Male
Biblical
Nativity, generation.
Male
Egyptian
, Amen the strong.
QUANTITATIVE PROTEOMICS
QUANTITATIVE PROTEOMICS
QUANTITATIVE PROTEOMICS
QUANTITATIVE PROTEOMICS
QUANTITATIVE PROTEOMICS
n.
The separation of a compound substance, by chemical processes, into its constituents, with a view to ascertain either (a) what elements it contains, or (b) how much of each element is present. The former is called qualitative, and the latter quantitative analysis.
adv.
So as to be measurable by quantity; quantitatively.
a.
Pertaining to, governed by, or in accordance with, mechanics, or the laws of motion; pertaining to the quantitative relations of force and matter, as distinguished from mental, vital, chemical, etc.; as, mechanical principles; a mechanical theory; mechanical deposits.
a.
Relating to quantity.
a.
Estimable according to quantity; quantitative.
n.
That science, or class of sciences, which treats of the exact relations existing between quantities or magnitudes, and of the methods by which, in accordance with these relations, quantities sought are deducible from other quantities known or supposed; the science of spatial and quantitative relations.
v. t.
A very small quantity of an element or compound in a given substance, especially when so small that the amount is not quantitatively determined in an analysis; -- hence, in stating an analysis, often contracted to tr.
a.
Relating to quality; having the character of quality.