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FGF19

  • FGF19
  • Protein-coding gene in the species Homo sapiens

    Fibroblast growth factor 19 is a protein that in humans is encoded by the FGF19 gene. It functions as a hormone, regulating bile acid synthesis, with effects

    FGF19

    FGF19

    FGF19

  • Rhodesian Ridgeback
  • Dog breed

    Andersson, L; Andersson, G (November 2007). "Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback

    Rhodesian Ridgeback

    Rhodesian Ridgeback

    Rhodesian_Ridgeback

  • Fibroblast growth factor
  • Family of proteins involved in anatomical development

    functions are still being characterized. FGF15 is the mouse ortholog of human FGF19 (there is no human FGF15) and, where their functions are shared, they are

    Fibroblast growth factor

    Fibroblast_growth_factor

  • FGF15
  • Mammalian protein found in Mus musculus

    fibroblast growth factor (FGF) family but, like FGF19, FGF21 and FGF23, has endocrine functions. FGF19 is the orthologous protein in humans. They are often

    FGF15

    FGF15

  • Bile acid malabsorption
  • Medical condition

    negatively regulated by the ileal hormone fibroblast growth factor 19 (FGF19), and lower levels of this hormone result in overproduction of bile acids

    Bile acid malabsorption

    Bile_acid_malabsorption

  • Klotho (biology)
  • Human enzyme

    β-klotho, and γ-klotho. α-klotho activates FGF23, and β-klotho activates FGF19 and FGF21. When the subfamily is not specified, the word "klotho" typically

    Klotho (biology)

    Klotho (biology)

    Klotho_(biology)

  • David Mangelsdorf
  • American biologist and chemist (1958–2025)

    discovered two new signaling pathways mediated by the endocrine factors FGF19 and FGF21, which has become a significant accomplishment in the field. He

    David Mangelsdorf

    David_Mangelsdorf

  • 7α-Hydroxy-4-cholesten-3-one
  • Chemical compound

    bile acid diarrhea associated with impaired negative feedback of CYP7A1 by FGF19. Russell DW (2003). "The enzymes, regulation, and genetics of bile acid

    7α-Hydroxy-4-cholesten-3-one

    7α-Hydroxy-4-cholesten-3-one

    7α-Hydroxy-4-cholesten-3-one

  • FGF15/19
  • Two orthologous fibroblast growth factors

    mouse; FGF19 was found in humans and other species. They share physiological functions and so are often referred to as FGF15/19 or as FGF15/FGF19. They

    FGF15/19

    FGF15/19

  • Aldafermin
  • Pharmaceutical compound

    Aldafermin is a fibroblast growth factor 19 (FGF19) analogue developed for non-alcoholic steatohepatitis. Babu, A.F.; Iannone, V.; Lok, J.; Gomez-Gallego

    Aldafermin

    Aldafermin

  • Bile acid
  • Steroid acid in the bile of animals

    during absorption in the intestine increases transcription and synthesis of FGF19, which then inhibits bile acid synthesis in the liver. Emerging evidence

    Bile acid

    Bile_acid

  • Obeticholic acid
  • Chemical compound

    median levels of FGF19, an ileal hormone that regulates increased hepatic bile acid synthesis, have been found in this condition. FGF19 is potently stimulated

    Obeticholic acid

    Obeticholic acid

    Obeticholic_acid

  • Fibroblast growth factor receptor 1
  • Protein found in humans

    FGF16 to FGF23. Fourteen of these, FGF1 to FGF6, FGF8, FGF10, FGF17, and FGF19 to FGF23 bind and activate FGFR1. FGFs binding to FGFR1 is promoted by their

    Fibroblast growth factor receptor 1

    Fibroblast growth factor receptor 1

    Fibroblast_growth_factor_receptor_1

  • Alexei Kharitonenkov
  • Russian biochemist

    Kharitonenkov, Alexei; DiMarchi, Richard D. (2018-07-01). "Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity". Molecular Metabolism

    Alexei Kharitonenkov

    Alexei Kharitonenkov

    Alexei_Kharitonenkov

  • Chenodeoxycholic acid
  • One of the main bile acids

    transcription of many genes is activated by FXR, including those encoding FGF19 and small heterodimer partner. In the European Union, chenodeoxycholic acid

    Chenodeoxycholic acid

    Chenodeoxycholic acid

    Chenodeoxycholic_acid

  • Dog coat genetics
  • Genetics behind dog coat

    Andersson, Leif; Andersson, Göran (November 2007). "Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback

    Dog coat genetics

    Dog coat genetics

    Dog_coat_genetics

  • Steven Kliewer
  • American biochemist

    discovered two new signaling pathways mediated by the endocrine factors FGF19 and FGF21, which has become a significant accomplishment in the field. "Steven

    Steven Kliewer

    Steven_Kliewer

  • List of human protein-coding genes 3
  • HGNC:3672; O43320 5650 FGF17 HGNC:3673; O60258 5651 FGF18 HGNC:3674; O76093 5652 FGF19 HGNC:3675; O95750 5653 FGF20 HGNC:3677; Q9NP95 5654 FGF21 HGNC:3678; Q9NSA1

    List of human protein-coding genes 3

    List_of_human_protein-coding_genes_3

  • LCTL
  • Protein-coding gene in the species Homo sapiens

    WE (December 2011). "Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cells". The Journal

    LCTL

    LCTL

    LCTL

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Online names & meanings

  • Ankhi
  • Girl/Female

    Bengali, Indian

    Ankhi

    Eyes

  • Fares
  • Surname or Lastname

    Muslim

    Fares

    Muslim : from a personal name based on Arabic fāris ‘horseman’, ‘knight’.English : variant spelling of Faires.

  • Harold
  • Boy/Male

    American, Anglo, Australian, British, Chinese, Christian, Danish, Dutch, English, French, German, Indian, Irish, Norse, Norwegian, Scandinavian, Swedish, Teutonic

    Harold

    Army-power; Army Ruler; Leader of an Army; Heroic Leader; Warrior; Powerful Ruler or Warrior

  • Helge
  • Boy/Male

    Australian, Danish, Finnish, Swedish

    Helge

    Holy; Dedicated to the Gods; Blessed; Prosperous; Successful

  • Deepalee
  • Girl/Female

    Hindu, Indian

    Deepalee

    Giving

  • Govindaraj | கோவீந்தாராஜ
  • Boy/Male

    Tamil

    Govindaraj | கோவீந்தாராஜ

    Lord Vishnu

  • Friduwulf
  • Boy/Male

    British, English

    Friduwulf

    Peaceful Wolf

  • Navadeep
  • Boy/Male

    Hindu, Indian, Tamil

    Navadeep

    Light

  • Zaahid
  • Boy/Male

    Afghan, Arabic, Gujarati, Hindu, Indian, Kannada, Muslim

    Zaahid

    Ascetic; Abstemious; Devotee

  • Craddick
  • Surname or Lastname

    English

    Craddick

    English : variant of Craddock.

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FGF19

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