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Medication
Pyrazinamide is a medication used to treat tuberculosis. For active tuberculosis, it is often used with rifampicin, isoniazid, and either streptomycin
Pyrazinamide
Disease treatment
involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months. During this initial period
Management_of_tuberculosis
Ability of a solid material to exist in more than one form or crystal structure
polymorphs, four of which are unstable in water and change to a stable form. Pyrazinamide has at least 4 polymorphs. All of them transforms to stable α form at
Crystal_polymorphism
Formulary by the World Health Organization
Cycloserine Delamanid Ethambutol Ethambutol/isoniazid/pyrazinamide/rifampicin (ethambutol + isoniazid + pyrazinamide + rifampicin) Ethambutol/isoniazid/rifampicin
WHO Model List of Essential Medicines
WHO_Model_List_of_Essential_Medicines
Infectious disease
Treatment with a combination of first-line drugs (Isoniazid, Rifampicin, Pyrazinamide, and Ethambutol) is preferred; they are more effective, and have fewer
Tuberculosis
Combination medication used for tuberculosis
Ethambutol/isoniazid/pyrazinamide/rifampicin, also known as ethambutol/isoniazid/pyrazinamide/rifampin, is a medication used for tuberculosis. It is a
Ethambutol/isoniazid/pyrazinamide/rifampicin
Ethambutol/isoniazid/pyrazinamide/rifampicin
Aminoglycoside antibiotic
tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. It is administered by injection into a vein or muscle. Common side effects
Streptomycin
Antibiotic for treatment of tuberculosis
For active tuberculosis, it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. It may also be used for atypical
Isoniazid
Chemical compound
a pyrazinamide (PZA) metabolite. Mycobacterium tuberculosis pyrazinamidase converts pyrazinamide into this compound, the active form of pyrazinamide. The
Pyrazinoic_acid
Combination drug
Rifampicin/isoniazid/pyrazinamide, also known as rifampin/isoniazid/pyrazinamide, and sold under the trade name Rifater, is a medication used to treat
Rifampicin/isoniazid/pyrazinamide
Rifampicin/isoniazid/pyrazinamide
Bacterial gene
nicotinamide to nicotinic acid where as pyrazinamidase converts the drug pyrazinamide to its active form pyrazinoic acid. Missense mutations in this gene in
PncA
Antibiotic medication
treatment of tuberculosis in combination with other antibiotics, such as pyrazinamide, isoniazid, and ethambutol. For the treatment of tuberculosis, it is
Rifampicin
Species of bacterium
The species does not reduce nitrate or niacin, and is resistant to pyrazinamide. It is sensitive to thiophene-2-carboxylic acid hydrazide.[citation needed]
Mycobacterium_bovis
Chemical compound
with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat Mycobacterium avium complex, and Mycobacterium
Ethambutol
Pharmaceutical drug classification
Pyrazinamide, ethambutol, isoniazid and lomefloxacin J04AM10 Pyrazinamide, ethambutol, protionamide and lomefloxacin J04AM11 Rifabutin, pyrazinamide and
ATC_code_J04
Drug class
urine uric acid levels. These drugs include all diuretics, pyrazinoate, pyrazinamide, ethambutol, niacin, and aspirin. The NSAID diclofenac has an antiuricosuric
Uricosuric
Abnormal change in size of the neck lymph nodes
tuberculosis (and inactive meningitis) includes rifampicin along with pyrazinamide, isoniazid, ethambutol, and streptomycin ("PIERS"). Scrofula caused by
Mycobacterial cervical lymphadenitis
Mycobacterial_cervical_lymphadenitis
Inflammation of the brain
the surface of the blood–brain barrier. Some drugs such as isoniazid, pyrazinamide, linezolid, metronidazole, fluconazole, and some fluoroquinolones have
Encephalitis
Peruvian biologist
tuberculosis, with a particular emphasis on the mechanisms of resistance to pyrazinamide in Mycobacterium tuberculosis. Sheen Cortavarría is also engaged in the
Patricia_Sheen
Form of arthritis causing swollen joints
inhibitors, angiotensin receptor blockers, beta blockers, ritonavir, and pyrazinamide. The immunosuppressive drugs ciclosporin and tacrolimus are also associated
Gout
Antituberculosis Inhibits peptide synthesis Isoniazid I.N.H. Antituberculosis Pyrazinamide Aldinamide Antituberculosis Rifampicin (Rifampin in US) Rifadin, Rimactane
List_of_antibiotics
Tuberculosis of the spine
initial 2-month intensive phase of Isoniazid (INH), Rifampin (RIF), Pyrazinamide (PZA), and Ethambutol (EMB). Following the 2-month initial phase, PZA
Pott's_disease
Medical condition
with isoniazid and rifampicin for six months, as well as ethambutol and pyrazinamide for the first two months. If there is evidence of meningitis, then treatment
Miliary_tuberculosis
Tumor-like mass resulting from the enlargement of a tuberculous lesion
commonly treated through the HRZE drug combination (Isoniazid, Rifampin, Pyrazinamide, Ethambutol) followed by maintenance therapy. Per international guidelines
Tuberculoma
pyridine 110–86–1 C5H5NO 2-pyridone 142–08–5 3-pyridinol 109–00–2 C5H5N3O pyrazinamide 98–96–4 C5H5N3O2 2-amino-nitropyridine 4214–76–0 C5H5N5 adenine 73–24–5
Glossary_of_chemical_formulae
Medical condition
medication regimen for at least 6 months. This includes isoniazid, rifampin, pyrazinamide, and ethambutol depending on susceptibility to the drug. While surgical
Tuberculous_lymphadenitis
Class of prescription drugs in India
PROPANOLOL HYDROCHLORIDE 416. PROPOFOL 417. PROTRISTYLINE HYDROCHLORIDE 418. PYRAZINAMIDE 419. PYRVINIUM 420. QUETIAPINE FUMERATE 421. QUINAPRIL 422. QUINIDINE
Schedule_H
Tuberculosis disgnostic and antibiotic sensitivity test
Capreomycin Cycloserine Rifampicin Thioacetazone Streptomycin Bedaquiline Pyrazinamide Rifater Vaccines BCG vaccine Experimental M72/AS01E MVA85A RBCG30 Resistance
GeneXpert_MTB/RIF
Bacteriology medium
Capreomycin Cycloserine Rifampicin Thioacetazone Streptomycin Bedaquiline Pyrazinamide Rifater Vaccines BCG vaccine Experimental M72/AS01E MVA85A RBCG30 Resistance
Mycobacteria growth indicator tube
Mycobacteria_growth_indicator_tube
Inflammation of membranes around the brain
meningitis consists of a 2-month induction regiment with isoniazid, rifampin, pyrazinamide, and ethambutol followed by an extended course (often 7-10 months) of
Chronic_meningitis
Topics referred to by the same term
Pyramide may refer to: Pyramide, brand name in Japan and Thailand for pyrazinamide, an anti-tuberculosis drug Pyramide (benzamide), a group of benzamides
Pyramide
Disease-causing bacteria
Standard "short" course: First 2 months, combination: Isoniazid Rifampicin Pyrazinamide Ethambutol Further 4 months, combination: Isoniazid Rifampicin BCG vaccine
Pathogenic_bacteria
State of tuberculosis infection without symptoms
given daily for 3 months. 2RZ — The 2-month regimen of rifampin and pyrazinamide is no longer recommended for treatment of LTBI because of the greatly
Latent_tuberculosis
Genus of bacteria
with transcription, ethambutol to hinder arabinogalactan synthesis, and pyrazinamide to impede coenzyme A synthesis. Mycobacteria have historically been categorized
Mycobacterium
Painful facial skin nodules due to infection by M. tuberculosis
therapy of drugs used for tuberculosis, such as rifampicin, isoniazid, and pyrazinamide (possibly with either streptomycin or ethambutol). Adequate vitamin D
Lupus_vulgaris
French multinational pharmaceutical and healthcare company
(Isoniazid/rifampicin), for tuberculosis. Rifater (Rifampicin/isoniazid/pyrazinamide), for tuberculosis. Tilade (Nedocromil), for asthma. Zagam (Sparfloxacin)
Sanofi
Medical condition
meningitis. The treatment of TB meningitis is isoniazid, rifampicin, pyrazinamide and ethambutol for two months, followed by isoniazid and rifampicin alone
Tuberculous_meningitis
Anti-tuberculosis and anti-inflammatory drug
rifampicin and pyrazinamide. Its potency is less than that of the current five first-line drugs (isoniazid, rifampicin, ethambutol, pyrazinamide, and streptomycin)
4-Aminosalicylic_acid
Antibiotic
retrieved 4 May 2008 Chan ED, Chatterjee D, Iseman MD, Heifets LB (2004). "Pyrazinamide, ethambutol, ethionamide, and aminoglycosides". In Rom WN, Garay SM (ed
Kanamycin_A
above). Pyrazinamide sensitivity (PZA) The deamidation of pyrazinamide to pyrazinoic acid (assumed to be the active component of the drug pyrazinamide) in
Phenotypic testing of mycobacteria
Phenotypic_testing_of_mycobacteria
Medical condition
rifampin, ciprofloxacin, and in some situations amikacin. Isoniazid and pyrazinamide are not effective for the therapy of MAC. Therapy should continue for
Mycobacterium avium-intracellulare infection
Mycobacterium_avium-intracellulare_infection
Species of bacterium
M. mageritense is resistant to isoniazid, cycloserine, capreomycin, pyrazinamide, and thiosemicarbazone. Most strains are also resistant to ethambutol
Mycobacterium_mageritense
Particulate respirator meeting the N95 standard
Capreomycin Cycloserine Rifampicin Thioacetazone Streptomycin Bedaquiline Pyrazinamide Rifater Vaccines BCG vaccine Experimental M72/AS01E MVA85A RBCG30 Resistance
N95_respirator
Excess uric acid in the blood
antiuricosurics. Other drugs and agents include diuretics, salicylates, pyrazinamide, ethambutol, nicotinic acid, ciclosporin, 2-ethylamino-1,3,4-thiadiazole
Hyperuricemia
Class of antibacterial drugs, subgroup of quinolones
theophylline, warfarin, antiviral agents, phenytoin, cyclosporine, rifampin, pyrazinamide, and cycloserine. Administration of quinolone antibiotics to a benzodiazepine-dependent
Quinolone_antibiotic
Tuberculosis of the renal and genital organs
pulmonary tuberculosis, consisting of isoniazid, rifampicin, ethambutol, and pyrazinamide. The standard treatment duration includes a two-month intensive phase
Urogenital_tuberculosis
Accumulation of excess fluid in the pleural cavity
recommended ATT regime is two months of isoniazid, rifampicin, ethambutol and pyrazinamide followed by four months of isoniazid, rifampicin and ethambutol. Empyema
Pleural_effusion
Topics referred to by the same term
PZA may refer to: Pyrazinamide, a medication used to treat tuberculosis PZA Loara, a Polish armored radar-directed self-propelled anti-aircraft gun system
PZA
British doctor
diseases and antibiotic therapy. He played a key role in the development of pyrazinamide as a treatment for tuberculosis and also did some of the earliest research
Harold_Lambert_(physician)
Anti-TB agent
treatment of tuberculosis. Although morphazinamide is metabolized to pyrazinamide within the body, the drug itself has intrinsic in vitro activity. Anvisa
Morinamide
Medical condition
standard, or first-line, anti-TB drugs (i.e., isoniazid, rifampicin, pyrazinamide and ethambutol). However, beginning with the first antibiotic treatment
Multidrug-resistant tuberculosis
Multidrug-resistant_tuberculosis
Italian healthcare company
results for other formulations, including the anti-tuberculosis drug pyrazinamide, of which Bracco is the leading world producer, which is included in
Bracco_(company)
Rare reaction to certain medications
combination, vancomycin, streptomycin Anti-tubercular: Ethambutol, isoniazid, pyrazinamide, rifampin Anti-retroviral: Abacavir, nevirapine Anti-hepatitis C: Boceprevir
Drug rash with eosinophilia and systemic symptoms
Drug_rash_with_eosinophilia_and_systemic_symptoms
Medication used to treat tuberculosis
BPaMZ combination treatment (bedaquiline + pretomanid + moxifloxacin + pyrazinamide). "Bedaquiline Fumarate". The American Society of Health-System Pharmacists
Bedaquiline
Chemical compound
modern synthesis is for 2-cyanopyrazine from 2-methylpyrazine [109-08-0]. Pyrazinamide [98-96-4] (1) 2-Cyanopyrazine [19847-12-2] (2) More modern syntheses
Acetylpyrazine
Public health initiative in India
short course of the four first line drugs; Isoniazid-H: Rifampicin-R, Pyrazinamide-Z, and Ethambutol-E. The drugs are administered through daily weight
National TB Elimination Program (India)
National_TB_Elimination_Program_(India)
Infection that develops from a pre-existing condition
history of Mycobacterium tuberculosis. Rifampicin Isoniazid Pyridoxine Pyrazinamide Ethambutol These current agents' doses/frequency will discontinue after
Opportunistic_infection
Medical condition
Etanercept anti (TNF-α) Isoniazid (antibiotic) Minocycline (antibiotic) Pyrazinamide (antibiotic) D-Penicillamine (anti-inflammatory) Carbamazepine (anticonvulsant)
Drug-induced lupus erythematosus
Drug-induced_lupus_erythematosus
Antidepressant
tranylcypromine. Drugs more effective for treatment of tuberculosis are isoniazid, pyrazinamide, ethambutol and rifampicin. Iproniazid was designed to treat tuberculosis
Iproniazid
60034-28-8 C5H5NO2 furamide 609-38-1 C5H5NO2 mecrylate 137-05-3 C5H5N3O pyrazinamide or pyrazine carboxamide 98-96-4 C5H5N5 adenine 73-24-5 C5H5Ni cyclopentadienylnickel
List of compounds with carbon number 5
List_of_compounds_with_carbon_number_5
Infectious disease and significant cause of mortality in India
them. The antibiotics most commonly used include isoniazid, rifampin, pyrazinamide, and ethambutol.The treatment under the National TB Elimination Program
Tuberculosis_in_India
Species of bacterium
grower and may take up to six weeks to grow. The species if resistant to pyrazinamide and susceptible to ethambutol.[citation needed] It is closely related
Mycobacterium_kansasii
Species of bacterium
susceptibility tests the type strain was resistant to isoniazid, rifampin, pyrazinamide, and cycloserine but susceptible to ethambutol, streptomycin, ethionamide
Mycobacterium_branderi
Combination medication
Health Organization's List of Essential Medicines. Ethambutol/isoniazid/pyrazinamide/rifampicin Stuart MC, Kouimtzi M, Hill SR, eds. (2009). WHO Model Formulary
Ethambutol/isoniazid/rifampicin
Ethambutol/isoniazid/rifampicin
Species of bacterium
also known to ferment nitrates. It is able to hydrolyze Tyrosine and Pyrazinamide. It does not metabolize urease, can hydrolyze esculin and can also ferment
Corynebacterium_striatum
Skin rash of small, red nodules due to infection by M. tuberculosis
and usually consists of a 4-drug regimen, i.e., isoniazid, rifampin, pyrazinamide, and ethambutol or streptomycin.[citation needed] Tuberculosis Tuberculosis
Tuberculosis_verrucosa_cutis
Formulary
Delamanid Ethambutol Ethionamide Isoniazid Isoniazid/pyrazinamide/rifampicin (isoniazid + pyrazinamide + rifampicin) Isoniazid/rifampicin (isoniazid + rifampicin)
WHO Model List of Essential Medicines for Children
WHO_Model_List_of_Essential_Medicines_for_Children
Enzyme
well-established, "first-line" drugs such as Rifampicin, Isoniazid, Pyrazinamide, and Ethambutol. The price point is already very low: US$16–35 will buy
Beta-ketoacyl-ACP synthase III
Beta-ketoacyl-ACP_synthase_III
physical examination prognosis patient P-Y Pack-year (years of smoking multiplied by average number of packs, or fraction thereof, per day) PZA pyrazinamide
List of medical abbreviations: P
List_of_medical_abbreviations:_P
Tuberculosis that is resistant to the most effective drugs
primary antitubercular drugs are Isoniazid, Rifampin, Ethambutol and Pyrazinamide. Drug Susceptibility testing is done by making a Lowenstein-Jensen medium
Extensively drug-resistant tuberculosis
Extensively_drug-resistant_tuberculosis
proximal tubule, providing uricosuric activity for the treatment of gout. Pyrazinamide: Used in tuberculosis treatment, it inhibits URAT1 and other uric acid
Renal tubular transport inhibitor
Renal_tubular_transport_inhibitor
PVF-K Pylera Pylori-Chek Breath Test Pyocidin Pyopen pyrantel (INN) pyrazinamide (INN) pyricarbate (INN) Pyridamal 100 pyridarone (INN) pyridofylline
List_of_drugs:_Ps–Pz
Substances which increase efficacy of drugs
chlorzoxazone, diclofenac, fexofenadine, ibuprofen, rifampicin, tetracycline, pyrazinamide). Allicin from garlic enhances the effect of the fungicide amphotericin
Bioenhancer
Indian organic chemist (born 1950)
synthesis of pharmaceutical and agrochemicals such as Diltiazem, Ondasetron, Pyrazinamide, Ketotifen, Mefloquin and Tamoxifin. He has published over 1300 peer-reviewed
Jhillu_Singh_Yadav
Species of bacterium
weeks. Susceptible to ethambutol, rifampin, streptomycin, resistant to pyrazinamide. Synthesis of α- and keto-mycolates and wax esters. no tolerance to 5%
Mycobacterium_conspicuum
British bacteriologist (1919–2018)
treatment period from at least 12 months to 6 months by using rifampicin and pyrazinamide in so-called "short-course" regimens which have been the basis of current
Denis_Mitchison
Species of bacterium
tuberculosis antibiotics isoniazid, ethambutol, rifampin, streptomycin and pyrazinamide. Differential characteristics Commercially available nucleic acid hybridisation
Mycobacterium_microti
Chemical compound
treatments, such as four or five of the drugs ethambutol, isoniazid, pyrazinamide, rifampicin, aminoglycoside antibiotics, and quinolones. Healing rates
Delamanid
S2CID 248357803. Duan, Meng-Fan; Mao, Jiang-Gao; Yang, Bing-Ping (2026). "Pyrazinamide–IBr: an organic–inorganic hybrid crystal exhibiting giant optical anisotropy"
Giant_birefringence
Medical condition
This therapy consists of a 2-month regimen of rifampin, isoniazid, pyrazinamide, and ethambutol followed by 4-months of rifampin and isoniazid. However
Tuberculous_pericarditis
Species of bacterium
Susceptible to ethambutol, rifampin and kanamycin. Resistant to isoniazid, pyrazinamide and streptomycin. Differential characteristics Similarities to M. tuberculosis
Mycobacterium_fallax
Medical condition
months' intensive therapy with isoniazid, rifampicin, ethambutol and pyrazinamide followed by a six to twelve month course of isoniazid and rifampicin
Tuberculous_dactylitis
Species of bacterium
and is susceptible to thiopene-2-carboxylic acid hydrazide (TCH) and pyrazinamide (PZA). M. africanum is also slower growing than M. tuberculosis, typically
Mycobacterium_africanum
South African biologist
home. Scholia has a profile for Valerie Mizrahi (Q22006961). Effects of Pyrazinamide on Fatty Acid Synthesis by Whole Mycobacterial Cells and Purified Fatty
Valerie_Mizrahi
Species of bacterium
split benzamide. M. hassiacum can also split urea, nicotinamide, and pyrazinamide. Mycobacterium hassiacum was first isolated from human urine in the German
Mycobacterium_hassiacum
Species of bacterium
45 °C, susceptible to isoniazid, rifampicin and ethambutol, resistant to pyrazinamide and cycloserine Differential characteristics: Differentiation from M
Mycobacterium_heidelbergense
Former tuberculosis sanatorium and hospital in Selah, Washington
These antibiotics, usually in combination with other drugs such as Pyrazinamide, Rifapentine, Rifampicin, Moxifloxacin and Ethambutol, are still used
Central Washington Tuberculosis Hospital
Central_Washington_Tuberculosis_Hospital
718 – pyrones MeSH D03.383.679.149 – amiloride MeSH D03.383.679.750 – pyrazinamide MeSH D03.383.710.100 – cilazapril MeSH D03.383.710.350 – luminol MeSH D03
List_of_MeSH_codes_(D03)
PYRAZINAMIDE
PYRAZINAMIDE
PYRAZINAMIDE
PYRAZINAMIDE
Girl/Female
Indian, Sanskrit
Powerful; Tremendous
Boy/Male
Hindu, Indian
Son of the Teacher
Boy/Male
Indian, Punjabi, Sikh
Meditation on Lord's Word
Girl/Female
Hindu
Boy/Male
Tamil
Himansu | ஹிமாநà¯à®¸à¯
The Moon
Male
English
Anglicized form of Hebrew Yabiyn, JABIN means "whom God observes." In the bible, this is the name of two kings of the Hazor.
Boy/Male
Indian, Sanskrit
One; Unique; Peerless
Girl/Female
Arabic, Australian, Muslim
Help
Girl/Female
Hindu, Indian, Marathi
Excitement
Girl/Female
Muslim
Indispensable
PYRAZINAMIDE
PYRAZINAMIDE
PYRAZINAMIDE
PYRAZINAMIDE
PYRAZINAMIDE