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PROBUCOL

  • Probucol
  • Chemical compound

    Probucol, sold under the trade name Lorelco among others, is an lipid-lowering agent initially developed for the treatment of coronary artery disease.

    Probucol

    Probucol

    Probucol

  • Lipid-lowering agent
  • Fat reducing drug

    we abandon probucol too soon?". Current Opinion in Lipidology. 26 (4): 304–16. doi:10.1097/MOL.0000000000000199. PMID 26125504. Probucol has been used

    Lipid-lowering agent

    Lipid-lowering_agent

  • Antioxidant
  • Compound that inhibits the oxidation of other molecules

    include lactones (esp. substituted benzofuranone) and acrylated bis-phenols. Probucol was originally designed as an antioxidant polymer stabilizer for rubber

    Antioxidant

    Antioxidant

  • Α-Tocopherol
  • Chemical compound

    Shichiri M, Ishida N, Hagihara Y, Yoshida Y, Kume A, Suzuki H (2019). "Probucol induces the generation of lipid peroxidation products in erythrocytes and

    Α-Tocopherol

    Α-Tocopherol

    Α-Tocopherol

  • Familial hypercholesterolemia
  • Genetic disorder characterized by high cholesterol levels

    the statins, clofibrate (an older fibrate that often caused gallstones), probucol (especially in large xanthomas) and thyroxine were used to reduce LDL cholesterol

    Familial hypercholesterolemia

    Familial hypercholesterolemia

    Familial_hypercholesterolemia

  • Low-density lipoprotein
  • One of the five major groups of lipoprotein

    LDL particles, yet can help some in combination with other strategies. Probucol, introduced in the 1970s. Now known to work through, among other ways,

    Low-density lipoprotein

    Low-density lipoprotein

    Low-density_lipoprotein

  • Drug-induced QT prolongation
  • Changes to heartbeat caused by a drug

    trafficking of the mature protein to the surface of the cell. This includes probucol, which appears to enhance the intercellular degradation of hERG; and several

    Drug-induced QT prolongation

    Drug-induced_QT_prolongation

  • 2,6-Di-tert-butylphenol
  • Chemical compound

    1098. 2,6-Di-tert-butylphenol is also used in the synthesis of CGP-7930, probucol, and nicanartine. The LD50 is 9200 mg/kg, indicating a low toxicity. 2

    2,6-Di-tert-butylphenol

    2,6-Di-tert-butylphenol

    2,6-Di-tert-butylphenol

  • ANGPTL3
  • Protein-coding gene in the species Homo sapiens

    Seino U, Miyazaki O, Hanyu O, Hirayama S, Saito T, et al. (October 2008). "Probucol markedly reduces HDL phospholipids and elevated prebeta1-HDL without delayed

    ANGPTL3

    ANGPTL3

    ANGPTL3

  • Cerivastatin
  • Chemical compound

    Those are bile acid sequestrants, nicotinic acid, fibric acid derivatives, probucol and HMG-CoA-reductase inhibitors. Cerivastatin mainly acts by competitively

    Cerivastatin

    Cerivastatin

    Cerivastatin

  • List of drugs: Pro–Prz
  • Probalan Probampacin probarbital sodium (INN) Proben-C probenecid (INN) probucol (INN) procainamide (INN) procaine (INN) Procalamine Procanbid Procapan

    List of drugs: Pro–Prz

    List_of_drugs:_Pro–Prz

  • Reverse cholesterol transport
  • increases macrophage-to-feces reverse transport, while gemfibrozil does not. Probucol decreases LDL-C but, alarmingly, also HDL-C. It promotes LDL uptake, inhibits

    Reverse cholesterol transport

    Reverse_cholesterol_transport

  • ATC code C10
  • Pharmaceutical drug classification

    Acipimox C10AD52 Nicotinic acid, combinations C10AX01 Dextrothyroxine C10AX02 Probucol C10AX03 Tiadenol C10AX05 Meglutol C10AX06 Omega-3-triglycerides C10AX07

    ATC code C10

    ATC_code_C10

  • Drug-eluting stent
  • Medical implant to treat narrowed arteries

    the case of the polymer-free DES, it utilizes an abluminal coating of probucol to control the release of sirolimus. On the other hand, the drug-coated

    Drug-eluting stent

    Drug-eluting stent

    Drug-eluting_stent

  • Self-microemulsifying drug delivery system
  • 9-nitrocamptothecin (9-NC) paclitaxel, and seocalcitol, alprostadil (intraurethral use), probucol, itraconazole, fenofibrate, acyclovir, simvastatin, xibornol, silymarin

    Self-microemulsifying drug delivery system

    Self-microemulsifying_drug_delivery_system

  • List of MeSH codes (D02)
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)

    List of MeSH codes (D02)

    List_of_MeSH_codes_(D02)

  • Heme oxygenase
  • Class of enzymes

    countless molecules including heavy metals, statins, paclitaxel, rapamycin, probucol, nitric oxide, sildenafil, carbon monoxide, carbon monoxide-releasing molecules

    Heme oxygenase

    Heme oxygenase

    Heme_oxygenase

  • Theresa M. Reineke
  • American chemist

    delivery. She used spray dried dispersions of the polymer with the drug probucol. Reineke was made a University of Minnesota Distinguished McKnight University

    Theresa M. Reineke

    Theresa_M._Reineke

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Online names & meanings

  • Zbygniew
  • Boy/Male

    Australian, Polish

    Zbygniew

    To do Away with Anger; To Dispel Anger

  • Benu | பேநுஂ
  • Girl/Female

    Tamil

    Benu | பேநுஂ

    Venus, Flute, Created with immense power

  • Geeravan
  • Boy/Male

    Hindu, Indian, Marathi

    Geeravan

    Brahma

  • Krithika
  • Girl/Female

    Hindu, Indian, Kannada, Tamil

    Krithika

    Admirable; Star

  • Tiina
  • Girl/Female

    Australian, Danish, Finnish

    Tiina

    Christian

  • Gurasees
  • Girl/Female

    Indian, Sikh

    Gurasees

    God's Blessing

  • Kalai | கலாஈ
  • Boy/Male

    Tamil

    Kalai | கலாஈ

    Nallavan

  • Humaina
  • Girl/Female

    Arabic, Muslim

    Humaina

    Able to Determine

  • Lavinder
  • Surname or Lastname

    English

    Lavinder

    English : variant spelling of Lavender.

  • Hidden
  • Surname or Lastname

    English

    Hidden

    English : habitational name from Hidden in Berkshire or Clayhidon in Devon, recorded in Domesday Book as Hidone, from Old English hī(e)g ‘hay’ + dūn ‘hill’.

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