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Group of toxins
Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. PT is involved in
Pertussis_toxin
Species of bacterium causing pertussis or whooping cough
factors include pertussis toxin, adenylate cyclase toxin, filamentous haemagglutinin, pertactin, pili, and tracheal cytotoxin. B. pertussis is an obligate
Bordetella_pertussis
Naturally occurring organic poison
A toxin is a naturally occurring poison produced by metabolic activities of living cells or organisms. They occur especially as proteins, often conjugated
Toxin
Protein family
PMID 20210554. Guiso N. 2009.Bordetella pertussis and pertussis vaccines. Clin. Infect. Dis. 49:1565–1569 "1.C.72 The Pertussis Toxin (PTX) Family". TCDB. Retrieved
AB5_toxin
Human disease caused by the bacteria Bordetella pertussis
and debris. TCT may contribute to the cough characteristic of pertussis. Pertussis toxin causes lymphocytosis by an unknown mechanism. The elevated number
Whooping_cough
Bacteria-produced protein complex and disease agent
observed in the pertussis toxin produced by Bordetella pertussis, another AB5 family member. However, instead of targeting Gsα, the pertussis toxin ADP-ribosylates
Cholera_toxin
Toxin harmful to nervous tissue
Neurotoxins are toxins that are destructive to nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological
Neurotoxin
Toxin produced by bacteria
pertussis. Bordetella bronchiseptica and Bordetella parapertussis, also able to cause pertussis-like symptoms, also produce adenylate cyclase toxin.
Adenylate_cyclase_toxin
Chemical compound
metabolizes to HT-2 mycotoxin (a major metabolite). The toxicity of T-2 toxin is due to its 12,13-epoxy ring. Epoxides are in general toxic compounds;
T-2_mycotoxin
Species of bacterium
that occurs during gas gangrene. Gas gangrene is caused by alpha toxin, or α-toxin, that embeds itself into the plasma membrane of cells and disrupts
Clostridium_perfringens
Toxin from bacteria that destroys or disrupts cells
vaccine protects against pertussis, tetanus and diphtheria infections, caused by the exotoxin-producing Bordetella pertussis, Clostridium tetani and Corynebacterium
Exotoxin
Type of toxic lectin
RY-sin) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus communis. The median
Ricin
Extremely potent neurotoxin
Tetanus toxin (TeNT) is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani in anaerobic conditions, causing tetanus
Tetanus_toxin
Family of related toxins
neuronal dysfunctions. 2011 German E. coli outbreak Cholera toxin Enterotoxin Pertussis toxin Friedman D; Court D (2001). "Bacteriophage lambda: alive and
Shiga_toxin
Vaccine protecting against whooping cough
Pertussis vaccine is a vaccine that protects against whooping cough (pertussis). There are two main types: whole-cell vaccines and acellular vaccines.
Pertussis_vaccine
Neurotoxin produced by Clostridium botulinum
Botulinum toxin, botulinum neurotoxin, or botox is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species, and it is
Botulinum_toxin
Exotoxin
Diphtheria toxin is an exotoxin secreted mainly by Corynebacterium diphtheriae (but also by Corynebacterium ulcerans and Corynebacterium pseudotuberculosis)
Diphtheria_toxin
Superantigen
Toxic shock syndrome toxin-1 (TSST-1) is a superantigen with a size of 22 kDa produced by 5 to 25% of Staphylococcus aureus isolates. It causes toxic
Toxic_shock_syndrome_toxin-1
Toxin produced by a fungus
improve the environment for further fungal proliferation. The production of toxins depends on the surrounding intrinsic and extrinsic environments and these
Mycotoxin
Genus of bacteria
described (B. pertussis, B. parapertussis, B. bronchiseptica) are sometimes referred to as the 'classical species'. Two of these (B. pertussis and B. bronchiseptica)
Bordetella
Family of toxins
Amatoxins are a subgroup of at least nine related cyclic peptide toxins found in three genera of deadly poisonous mushrooms (Amanita, Galerina and Lepiota)
Amatoxin
Toxin produced by microorganisms
with inhalation. Bordetella pertussis targets cilia of the upper respiratory tract which are damaged by the pertussis toxin, an ADP-ribosyltransferase
Microbial_toxin
Highly modified saliva containing zootoxins
surface of muscle cells and cause depolarisation → the toxin prevents muscle contraction. These toxins may cause the heart to beat irregularly or stop beating
Snake_venom
Chemical compound
and batrachotoxinin A. Due to the difficulty of handling such a potent toxin and the minuscule amount that could be collected, a comprehensive structure
Batrachotoxin
Species of endospore forming bacterium
produce the toxin. Botulinum toxin can cause botulism, a severe flaccid paralytic disease in humans and other animals. The botulinum toxin is the most
Clostridium_botulinum
Insecticide
pore-forming toxins produced by Bacillus thuringiensis species of bacteria. They are useful for their insecticidal action and are the primary toxin produced
Delta_endotoxins
Family of amphibians
case, toxic arthropods – from which they absorb and reuse the consumed toxins. The secretion of these chemicals is released by the granular glands of
Poison_dart_frog
Neurotoxin
porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Although tetrodotoxin was discovered in these fish, it is found in several
Tetrodotoxin
Group of chemical compounds
smelled or tasted and cannot be destroyed by cooking. Rapid testing for this toxin in food is not standard. Some ciguatoxins lower the threshold for opening
Ciguatoxin
Tripartite protein complex secreted by virulent strains of Bacillus anthracis
Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium, Bacillus anthracis—the causative agent of anthrax. The toxin was
Anthrax_toxin
Foodborne illness
lethargy. The onset of symptoms varies with the amount of toxin absorbed. If a large quantity of toxins is consumed, symptoms may appear within half an hour
Ciguatera_fish_poisoning
Respiratory toxin
Adenylate cyclase toxin (CyaA) is released from bacterium Bordetella pertussis by the T1SS (Type 1 secretion system) and released in the host's respiratory
CyaA
Paralytic shellfish toxin
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin. Ingestion of saxitoxin by humans, usually by consumption of shellfish contaminated
Saxitoxin
Combination vaccine
the bacterium that causes pertussis or pertussis antigens. The term toxoid refers to vaccines which use an inactivated toxin produced by the pathogen which
DPT_vaccine
Type of molecules produced by a pathogen that might cause potential harmful effects
potent known exotoxins are the tetanus toxin (tetanospasmin) secreted by Clostridium tetani and the botulinum toxin secreted by Clostridium botulinum. Exotoxins
Virulence_factor
Group of poisons produced by molds
improvements were seen. Mycotoxins in animal feed Sterigmatocystin, a related toxin Other ways in which aspergillus can cause disease in mammals: Aspergillosis
Aflatoxin
Chemical compound
eight amino acids. It is possibly the most deadly of all the amatoxins, toxins found in several species of the mushroom genus Amanita, one being the death
Α-Amanitin
Class of chemical compounds
mushrooms. The exact composition varies greatly with the specific source of the toxin. Bufotoxins can contain 5-MeO-DMT, bufagins, bufalin, bufotalin, bufotenin
Bufotoxin
Gill-bearing non-tetrapod aquatic vertebrates
toxin/Verotoxin E. coli heat-stable enterotoxin Cholera toxin/Heat-labile enterotoxin Pertussis toxin Pseudomonas exotoxin Extracellular adenylate cyclase
Fish
Poisoning of heart electrophysiology or muscle
cardiomyopathy Recreational drugs: cocaine, methamphetamine Biological toxins such as diphtheria toxin Radiation therapy is known to cause radiation-induced heart
Cardiotoxicity
Chemical compound
toxin/Verotoxin E. coli heat-stable enterotoxin Cholera toxin/Heat-labile enterotoxin Pertussis toxin Pseudomonas exotoxin Extracellular adenylate cyclase
Resiniferatoxin
Protein family
The AB toxins are two-component protein complexes secreted by a number of pathogenic bacteria, though there is a pore-forming AB toxin found in the eggs
AB_toxin
Type of vaccine
contain antigens like pertussis toxin, adenylate cyclase toxin, lipooligosaccharides and agglutinogens. The whole-cell pertussis vaccine is prepared by
Whole-cell_vaccine
Laboratory technique to multiply a DNA sample for study
the pertussis toxin. Because PCR has a high sensitivity for the toxin and a rapid turnaround time, it is very efficient for diagnosing pertussis when
Polymerase_chain_reaction
Large family of chemically related mycotoxins
these are neosolaniol with a hydroxyl substitution at carbon 8, and T-2 toxin with an ester substitution at carbon 8. Type B trichothecenes are classified
Trichothecene
Group of neurotoxins in spider venom
five insecticidal toxins, termed α, β, γ, δ and ε-latroinsectotoxins, one vertebrate-specific neurotoxin, α-latrotoxin, and one toxin affecting crustaceans
Latrotoxin
InterPro Family
proteins are substrates for pertussis toxin, produced by Bordetella pertussis, the infectious agent in whooping cough. Pertussis toxin is an ADP-ribosylase enzyme
Gi_alpha_subunit
Class of molecules found in the outer membrane of Gram-negative bacteria
with LPS, although there are a few endotoxins (in the original sense of toxins that are inside the bacterial cell that are released when the cell disintegrates)
Lipopolysaccharide
Cytotoxin produced by Clostridioides difficile
Clostridioides difficile toxin B (TcdB) is a cytotoxin produced by the bacteria Clostridioides difficile. It is one of two major kinds of toxins produced by C.
Clostridioides difficile toxin B
Clostridioides_difficile_toxin_B
Antigen which strongly activates the immune system
are released upon infection as extracellular mature toxins. The sequences of these bacterial toxins are relatively conserved among the different subgroups
Superantigen
Chemical compound
directly linked to the three-finger toxin superfamily. Among them, α-bungarotoxin (α-BTX) stands out, being a peptide toxin produced by the Taiwanese banded
Α-Bungarotoxin
Chemical compound
toxin/Verotoxin E. coli heat-stable enterotoxin Cholera toxin/Heat-labile enterotoxin Pertussis toxin Pseudomonas exotoxin Extracellular adenylate cyclase
Muscarine
Group of exotoxins from bacteria
The C-terminal domain of the adenylate cyclase toxin (ACT or CyaA; TC# 1.C.11.1.4) of Bordetella pertussis forms a small cation-selective channel, disrupting
RTX_toxin
Cytotoxin produced by Clostridioides difficile
Clostridioides difficile toxin A (TcdA) is a toxin produced by the bacteria Clostridioides difficile, formerly known as Clostridium difficile. It is similar
Clostridioides difficile toxin A
Clostridioides_difficile_toxin_A
Chemical compound
toxin/Verotoxin E. coli heat-stable enterotoxin Cholera toxin/Heat-labile enterotoxin Pertussis toxin Pseudomonas exotoxin Extracellular adenylate cyclase
Cantharidin
Toxic chemical from some poison dart frogs
IUCN protected status in 1984. Furthermore, these frogs do not produce the toxin when bred and reared in captivity, because they do not synthesize epibatidine
Epibatidine
Topics referred to by the same term
Pararosaniline, Toluidine histological stain Percutaneous surgery Pertussis toxin, a protein-based exotoxin which causes whooping cough Petunidin, an
PT
Reports suggesting that combined administration of an HPV vaccine and pertussis toxin caused neurological damage in mice. The paper attracted media attention
HPV_vaccination_in_Japan
Chemical compound
concern to livestock and poultry producers, namely deoxynivalenol, T-2 toxin, HT-2 toxin, diacetoxyscirpenol (DAS) and zearalenone. Particularly, ZEN is produced
Zearalenone
Chemical compound
studies have found that because 3-nitropropionic acid is a mitochondrial toxin, it can produce striatal alterations in rats similar to those observed in
3-Nitropropionic_acid
Toxin produced by the bacterium Clostridium perfringens
Clostridium perfringens alpha toxin is a toxin produced by the bacterium Clostridium perfringens (C. perfringens) and is responsible for gas gangrene and
Clostridium perfringens alpha toxin
Clostridium_perfringens_alpha_toxin
Fungal toxic chemical in grains
associated with lower amount of vomitoxin in wheat grain due to leaching of toxins. Furthermore, deoxynivalenol contents are significantly affected by the
Vomitoxin
Subtype of white blood cell
a low neutrophil count might be caused by lymphoma. Pertussis toxin (PTx) of Bordetella pertussis, formerly known as lymphocytosis-promoting factor, causes
Lymphocyte
Weakened form of a toxin, often used for vaccines
A toxoid is an inactivated toxin (usually an exotoxin) whose toxicity has been suppressed while retaining its immunogenicity. This is usually achieved
Toxoid
Toxin from a microorganism affecting the intestines
(epithelial) cells of the intestinal wall. They are mostly pore-forming toxins (mostly chloride pores), secreted by bacteria, that assemble to form pores
Enterotoxin
Chemical compound
PMID 1677747. S2CID 38895357. Kawai, Nobufumi (1991). "Spider toxin and pertussis toxin differentiate post- and presynaptic glutamate receptors". Neuroscience
Joro_toxin
Vaccines used to prevent tetanus
the DTaP vaccine, which is three inactive toxins in one injection. DTaP protects against diphtheria, pertussis, and tetanus. This acellular vaccine is safer
Tetanus_vaccine
Neurotoxic phospholipase
Taipoxin like many other pre-synaptic neurotoxins are phospholipase A2 (PLA2) toxins, which inhibit/complete block the release of the motor transmitter acetylcholine
Taipoxin
Cytotoxin forming pores in cell membranes
leukocidin (PVL) is a cytotoxin—one of the β-pore-forming toxins. PVL is a bicomponent pore-forming toxin composed of LukS-PV and LukF-PV subunits. These assemble
Panton–Valentine_leukocidin
Addition of one or more ADP-ribose moieties to a protein
A of Pseudomonas aeruginosa; pertussis toxin of B. pertussis; C3 toxin of C. botulinum; and diphtheria toxin of Corynebacterium diphtheriae. Histone
ADP-ribosylation
aureus delta toxin is a toxin produced by Staphylococcus aureus. It has a wide spectrum of cytolytic activity. It is among other toxins produced by S
Staphylococcus aureus delta toxin
Staphylococcus_aureus_delta_toxin
Enterotoxin produced by the bacteria Staphylococcus aureus
often starting within a few hours of ingestion. Being quite stable, the toxin may remain active even after the contaminating bacteria are killed. It can
Enterotoxin_type_B
Protein-coding gene in the species Homo sapiens, named for ketazocine
where they exert negative inotropic and lusitropic effects through pertussis toxin-sensitive Gi/o protein signaling. Healthy human kidney expresses KOR
Κ-opioid_receptor
Respiratory sounds associated with abnormal lung conditions
descriptions. Bronchophony Egophony Consumption Whooping cough Croup Pertussis toxin Allergic asthma Respiratory sounds Jones D (2003) [1917], Roach P,
Crackles
Alpha-toxin, also known as alpha-hemolysin (Hla), is the major cytotoxic agent released by bacterium Staphylococcus aureus and the first identified member
Staphylococcus aureus alpha toxin
Staphylococcus_aureus_alpha_toxin
Broad-spectrum calcium channel blocker
Phoneutria nigriventer toxin-3 is more commonly referred to as PhTx3. The PhTx3 neurotoxin is a broad-spectrum calcium channel blocker that inhibits glutamate
Phoneutria nigriventer toxin-3
Phoneutria_nigriventer_toxin-3
Neurotoxin
neurotoxin isolated from the black mamba Dendroaspis p. polylepis venom. This toxin consists of 60 amino acids with four disulfide bonds. Calciseptine specifically
Calciseptine
ROMK1. Lq2 is also known as Potassium channel toxin alpha-KTx 1.2, Charybdotoxin-2, ChTX-Lq2, ChTx-d, Toxin 18-2 or Lqh 18-2. The name Lq2 refers to the
Lq2
Species of bacterium
rarely infects humans. Closely related to B. pertussis—the obligate human pathogen that causes pertussis (whooping cough); B. bronchiseptica can persist
Bordetella_bronchiseptica
Chemical compound
toxin/Verotoxin E. coli heat-stable enterotoxin Cholera toxin/Heat-labile enterotoxin Pertussis toxin Pseudomonas exotoxin Extracellular adenylate cyclase
Amanin
Protein-produced toxins that create pores in cell membrane
Pore-forming proteins (PFTs, also known as pore-forming toxins) are usually produced by bacteria, and include a number of protein exotoxins but may also
Pore-forming_toxin
Chemical compound
cells, have also been investigated in cellular models. Some of the bufagin toxins are used in low doses in traditional Chinese medicine for similar applications
Bufagin
Type of drugs
Stimulation of CB1 receptor causes the dissociation of the βγ subunits of pertussis toxin-sensitive G proteins (Gi /Go) from the α subunit (Giα) which then contributes
Synthetic_drug
Controlled release of substances by cells or tissues
gastric carcinogenesis. Bordetella pertussis, the causative agent of whooping cough, secretes the pertussis toxin partly through the type IV system. Legionella
Secretion
Lipid component of lipopolysaccharide endotoxins of gram-negative bacteria
toxin/Verotoxin E. coli heat-stable enterotoxin Cholera toxin/Heat-labile enterotoxin Pertussis toxin Pseudomonas exotoxin Extracellular adenylate cyclase
Lipid_A
Protein domain
lupus erythematosus Other pyrin Rho-GTPase inactivation (i.e. B. pertussis (pertussis toxin), B. cenocepacia (nosocomial pneumonia), C. botulinum (botulism)
Pyrin_domain
Toxins that destroy red blood cells
Haemotoxins, hemotoxins or hematotoxins are toxins that destroy red blood cells, disrupt blood clotting, and/or cause organ degeneration and generalized
Hemotoxin
Class of bacterial toxins
water from intestinal cells. Heat-stable toxin 1 of entero-aggregative Escherichia coli (EAST1) is a small toxin. It is not, however, solely associated
Heat-stable_enterotoxin
Naturally occurring glutamate receptor agonist neurotoxin
toxin/Verotoxin E. coli heat-stable enterotoxin Cholera toxin/Heat-labile enterotoxin Pertussis toxin Pseudomonas exotoxin Extracellular adenylate cyclase
Ibotenic_acid
Chemical compound
in dendrotoxin specificity by mediating the interactions of individual toxins to their individual target sites. This not only helps explain the stringent
Dendrotoxin
Crystal protein
order to confer pest resistance on those plants An accepted model of the toxin is when it becomes ingested by lepidoptera, the larvae becomes activated
Cry1Ac
Exotoxin produced by Pseudomonas aeruginosa
aeruginosa. Vibrio cholerae produces a similar protein called the Cholix toxin (Q5EK40). It inhibits elongation factor-2. It does so by ADP-ribosylation
Pseudomonas_exotoxin
Bacterial infection characterized by muscle spasms
and pertussis. For adults and children over seven, the Td vaccine (tetanus and diphtheria) or Tdap (tetanus, diphtheria, and acellular pertussis) is commonly
Tetanus
Protein domain
hector insect toxin also known as AaHIT is a scorpion toxin which affects voltage-gated sodium channels. Four different insect toxins, namely AaHIT1
Androctonus australis hector insect toxin
Androctonus_australis_hector_insect_toxin
found in the venom, Pi2. Pi3 toxin stands for Pandinus imperator-3 toxin. It is also known as pandinotoxin-beta and toxin PiTX-K-beta. The classification
Pandinus imperator (Pi3) toxin
Pandinus_imperator_(Pi3)_toxin
Protein family
homologues. However, encoded closely to the active subunit cdtb, the Pertussis-like toxin A and B (pltA/pltB) have been shown to be essential for cellular
Cytolethal_distending_toxin
Signal cascade used for cell to cell communication
bucladesine (dibutyryl cAMP, db cAMP) - also a phosphodiesterase inhibitor pertussis toxin, which increases cAMP levels by inhibiting Gi to its GDP (inactive)
CAMP-dependent_pathway
Chemical compound
toxin/Verotoxin E. coli heat-stable enterotoxin Cholera toxin/Heat-labile enterotoxin Pertussis toxin Pseudomonas exotoxin Extracellular adenylate cyclase
Citrinin
Chemical compound
Satratoxin-H, a trichothecene mycotoxin, is a naturally occurring toxin produced by the ascomycetes Stachybotrys chartarum and Trichoderma cornu-damae
Satratoxin-H
Protein complexes present on the cell membranes of bacteria for secretion of substances
induce gastric cancer. Bordetella pertussis, the causative bacterium of whooping cough, secretes its pertussis toxin partly through T4SS. Legionella pneumophila
Bacterial_secretion_system
PERTUSSIS TOXIN
PERTUSSIS TOXIN
PERTUSSIS TOXIN
PERTUSSIS TOXIN
Surname or Lastname
English
English : probably a variant of Dunford.
Girl/Female
German
Bright
Girl/Female
Indian, Telugu
Just Good Feeling to Listen
Surname or Lastname
English (Lancashire)
English (Lancashire) : habitational name from a place in the parish of Wigan (now in Greater Manchester), so called from Old English mearc ‘boundary’ + lanu ‘lane’.English (Lancashire) : topographic name for someone who lived by a stretch of border or boundary land (see Mark) or a status name for someone who held land with an annual value of one mark.
Girl/Female
Tamil
Hemkesh | ஹேமà¯à®•à¯‡à®·
Lord Shiva
Boy/Male
Australian, French, Latin, Polish
Patrician; Nobleman
Boy/Male
Hindu
Nectar, Wine
Boy/Male
Hindu
One who has the missile Khatvangin in his hand
Girl/Female
British, English, Spanish
Purity; Pure
Boy/Male
Indian
King; Lovely
PERTUSSIS TOXIN
PERTUSSIS TOXIN
PERTUSSIS TOXIN
PERTUSSIS TOXIN
PERTUSSIS TOXIN
n.
Alt. of Toxine
n.
The whooping cough.
n.
A poisonous product formed by pathogenic bacteria, as a toxic proteid or poisonous ptomaine.