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Search references for PDE4D. Phrases containing PDE4D
See searches and references containing PDE4D!PDE4D
Protein-coding gene in the species Homo sapiens
phosphodiesterase 4D is an enzyme that in humans is encoded by the PDE4D gene. The PDE4D gene is complex and has at least 9 different isoforms that encode
PDE4D
Chemical compound
investigational new drug that is being evaluated to treat fragile X syndrome. It is a PDE4D allosteric inhibitor. It works by inhibiting breakdown of cyclic AMP (cAMP)
Zatolmilast
Class of chemical compounds
obstructive pulmonary disease (COPD), asthma and rheumatoid arthritis. PDE4D inhibition, along with PDE4A inhibition also appears to be responsible for
PDE4_inhibitor
Index of chemical compounds with the same name
types of the enzyme phosphodiesterase 4 (PDE4) are known: PDE4A PDE4B PDE4C PDE4D 3',5'-cyclic-AMP phosphodiesterase Phosphodiesterase (PDE) PDE4 inhibitor
Phosphodiesterase_4
Medical condition
believed to be caused by mutations in the PRKAR1A gene (type 1) or the PDE4D gene (type 2). It has been suggested that the condition might be genetically
Acrodysostosis
Class of enzymes
PDE1B, PDE1B2, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4B5, PDE4C, PDE4D, PDE5A, PDE6A, PDE6B, PDE6C, PDE7A, PDE7B, PDE8A, PDE8B, PDE9A, PDE10A,
Cyclic nucleotide phosphodiesterase
Cyclic_nucleotide_phosphodiesterase
Cytogenetic feature
FRA4E FRA4F (GRID2 gene) FRA5A FRA5B FRA5C FRA5D FRA5E FRA5F FRA5G FRA5H (PDE4D gene) FRA6A FRA6B FRA6C FRA6D FRA6E (PARK2 gene) FRA6F FRA6G FRA6H FRA7A
Chromosomal_fragile_site
Vertebrate protein involved in the formation of microtubules
brain size evolution. Myomegalin (PDE4DIP) has been shown to interact with PDE4D. The protein was discovered in 2000 and was so named because it was highly
Myomegalin
P27815 11862 PDE4B HGNC:8781; Q07343 11863 PDE4C HGNC:8782; Q08493 11864 PDE4D HGNC:8783; Q08499 11865 PDE4DIP HGNC:15580; Q5VU43 11866 PDE5A HGNC:8784;
List of human protein-coding genes 6
List_of_human_protein-coding_genes_6
Drug discovery
formed by the conserved glutamine (Q817 in PDE5A, Q443 in PDE4B and Q369 in PDE4D) and the P clamp (a hydrophobic clamp at the narrow side of the active sites
Discovery and development of phosphodiesterase 5 inhibitors
Discovery_and_development_of_phosphodiesterase_5_inhibitors
Mammalian protein found in humans
Arellano J, Duque A, Rakic P, et al. (December 2023). "Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer
Metabotropic glutamate receptor 3
Metabotropic_glutamate_receptor_3
Protein-coding gene in the species Homo sapiens
receptor, CD18, CD29 Cyclin A1 EIF6, FYN, IFNAR2, Janus kinase 1 OTUB1, P73, PDE4D, PRKCB1, PRKCE, PTPRM, RAS p21 protein activator 1, ST7, STAT1, Src, and
Receptor for activated C kinase 1
Receptor_for_activated_C_kinase_1
Protein-coding gene in the species Homo sapiens
Conti M (1995). "Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4". Cytogenetics
PDE4B
Class of enzymes
inhibitors residing in the active site. The co-crystal structures for PDE4B, PDE4D and PDE5A have revealed two common features of inhibitor binding to PDEs
Phosphodiesterase_2
Protein-coding gene in the species Homo sapiens
of DEPDC1B includes 5 other genes. Downstream are two genes SEPT21 and PDE4D. Upstream are another two genes ELOV7 and KRT8P31. On the complement strand
DEPDC1B
PDE4D
PDE4D
PDE4D
PDE4D
Girl/Female
Indian
Boy/Male
Hindu, Indian, Punjabi, Sikh
One Blessed with the Guru's Grace
Boy/Male
Tamil
Dhroneshwar | தà¯à®°à¯‹à®¨à¯‡à®·à¯à®µà®°Â
Dronacharya & Shiva
Girl/Female
Tamil
Flower
Boy/Male
Indian, Sanskrit
Boss of Universe; God of Universe
Surname or Lastname
English
English : variant spelling of Steer.
Girl/Female
Hindu
Name of a river
Boy/Male
Indian, Tamil
He will be Praised by Many
Surname or Lastname
English
English : patronymic or genitive from Dane, variant of Dean 2, i.e. ‘son (or servant) of the dean’.Dutch : patronymic from a short form of Daniel.Czech and Slovak (Daneš) : variant of Daňek (see Danek).
Girl/Female
Greek Muslim
From Sheba.
PDE4D
PDE4D
PDE4D
PDE4D
PDE4D