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Open reading frame
ORF1ab (also ORF1a/b) refers collectively to two open reading frames (ORFs), ORF1a and ORF1b, that are conserved in the genomes of nidoviruses, a group
ORF1ab
Protein in the Coronavirus genome
non-structural protein in the Coronavirus genome. Its gene is part of the ORF1ab reading frame and it is part of the pp1ab polyprotein; it is cleaved by
Nsp12
Subfamily of viruses in the family Coronaviridae
The genome organization for a coronavirus is 5′-leader-UTR-replicase (ORF1ab)-spike (S)-envelope (E)-membrane (M)-nucleocapsid (N)-3′UTR-poly (A) tail
Coronavirus
Variant of SARS-CoV-2, the virus that causes COVID-19
by "ORF1ab+N" or "ORF1ab+N+S"). However, further uncertainty exists given that not all "New UK variant compatible" SGTF cases (positive on ORF1ab and
SARS-CoV-2_Alpha_variant
20C/S:452R, is defined by five distinct mutations (I4205V and D1183Y in the ORF1ab gene, and S13I, W152C, L452R in the spike protein's S-gene), of which the
Variants_of_SARS-CoV-2
Species of virus
O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1). Vijgen, Leen; Keyaerts, Els; Moës, Elien;
Human_coronavirus_OC43
Variant of the virus SARS-CoV-2
in S-gene, A119S in N-gene, 5’UTR C100U, plus L3468V and synC11824U in ORF1ab-gene. Other mutations commonly found in P.2 are: 3’UTR C29754U, F120F (synC28253U)
SARS-CoV-2_Gamma_variant
Species of coronavirus causing SARS and COVID-19
papain-like proteinase (PLpro) instead of two in the open reading frame ORF1ab. SARSr-CoV was determined to be an early split-off from the betacoronaviruses
SARS-related_coronavirus
Species of virus
O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1). Lau, S. K. P.; Woo, P. C. Y.; Yip, C
Human_coronavirus_HKU1
Protein family
(Pisuviricota) VSPs: viral envelope Spike Envelope Membrane Nucleocapsid VNPs: ORF1ab 3C-like protease (NS5) ORF3a ORF3b ORF3c ORF3d ORF6 ORF7a ORF7b ORF8 ORF9b
P24_capsid_protein
Genus of viruses
overall structure of β-CoV genome is similar to that of other CoVs, with an ORF1ab replicase polyprotein (rep, pp1ab) preceding other elements. This polyprotein
Betacoronavirus
Virus matrix protein
(Pisuviricota) VSPs: viral envelope Spike Envelope Membrane Nucleocapsid VNPs: ORF1ab 3C-like protease (NS5) ORF3a ORF3b ORF3c ORF3d ORF6 ORF7a ORF7b ORF8 ORF9b
VP40
Breakdown of proteins into smaller polypeptides or amino acids
the polyprotein include gag (group-specific antigen) in retroviruses and ORF1ab in Nidovirales. The latter name refers to the fact that a slippery sequence
Proteolysis
products ORF1a and ORF1ab In the equine arterivirus (EAV), the replicase gene is translated into open reading frame 1a (ORF1a) and ORF1ab [polyprotein]s.
Equine arterivirus serine peptidase
Equine_arterivirus_serine_peptidase
Protein-coding gene in the species Homo sapiens
were identified with distinct strains of coronavirus. An interaction with orf1ab polyprotein of the human coronavirus strain HKU1(HCov-HKU1) was shown in
ISLR
Variant of the SARS-Cov-2 virus
CDC. The variant has five defining mutations (I4205V and D1183Y in the ORF1ab gene, and S13I, W152C, L452R in the spike protein's S-gene), of which the
SARS-CoV-2_Epsilon_variant
Glycoprotein spike on a viral capsid or viral envelope
spike (S) gene was the second most frequently mutated in the genome, after ORF1ab (which encodes most of the virus' nonstructural proteins). The evolution
Coronavirus_spike_protein
Family of viruses
major open reading frames (ORFs). Two overlapping ORFs, together known as ORF1ab, are at the 5'-end, encoding the major non-structural proteins and are expressed
Mesoniviridae
Species of virus
long. The genome is dominated by two large open reading frames, ORF1a and ORF1ab; these code for two polyproteins, PP1a and PP1ab. These polyproteins are
Lactate dehydrogenase elevating virus
Lactate_dehydrogenase_elevating_virus
COVID-19 vaccine research organization
optional peptides. Certain T cell epitope peptides were also changed. "Orf1ab 5528T" replaced "Orf1 1636T" in the list of core peptides, because the former
Rapid Deployment Vaccine Collaborative
Rapid_Deployment_Vaccine_Collaborative
Species of virus
O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1). Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna
Betacoronavirus_1
Subgenus of viruses
O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1). Woo, Patrick C. Y.; Wang, Ming; Lau,
Embecovirus
Papain-like protease protein domain
PLPro domains are expressed as part of the large polyprotein encoded by the ORF1ab gene. PLPro domains are responsible for proteolytic processing of the polyprotein
Nidoviral papain-like protease
Nidoviral_papain-like_protease
transcription and replication of viral RNAs. An alternative name is the ORF1ab polyprotein. It contains the polyprotein cleavage proteinases. The optimum
SNAP47
Protein-coding gene in the species Homo sapiens
protein 2, NSP2 is one of the many non-structural proteins encoded in the orf1ab polyprotein. NSP2 alters the host cell environment rather than contribute
SLC46A3
Species of virus
O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1). "Virus Taxonomy: 2018 Release". International
Murine_coronavirus
compared to other SARSr-CoV (by nucleotide %) Strain Full-length genome ORF1ab S RBM ORF3a E M ORF6 ORF7a ORF7b ORF8 N ORF10 RaTG13 96.10% 96.50% 92.30%
RacCS203
ORF1AB
ORF1AB
ORF1AB
ORF1AB
Boy/Male
Tamil
Water Lily, Fleshless
Boy/Male
Russian
Abbreviation of Elijah 'My God is Jehovah.
Boy/Male
Hindu, Indian
Protected by Brahma
Girl/Female
Greek American French Gaelic Celtic English Irish
Beautiful.
Boy/Male
American, Australian, Celtic, Christian, Scottish
From the Dark River; Form of Douglas
Boy/Male
Gujarati, Hindu, Indian, Kannada
Another Name of a Sage Shounak
Female
Welsh
Pet form of Welsh Siân, SIANI means "God is gracious."
Girl/Female
Arabic, Indian, Muslim, Punjabi, Sikh
One who Stands Surety for Another One who Helps
Girl/Female
Hindu, Indian, Malayalam
Part of Goddess Laxmi
Boy/Male
Hindu, Indian
Small; Lovely; Sweet
ORF1AB
ORF1AB
ORF1AB
ORF1AB
ORF1AB