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Protein-coding gene in the species Homo sapiens
domains-containing protein 2 is a protein that in humans is encoded by the NLRP2 gene. NALP proteins, such as NALP2, are characterized by an N-terminal pyrin
NLRP2
Class of proteins
(C for CARD): NOD1, NOD2, NLRC3, NLRC4, NLRC5 NLRP (P for PYD): NLRP1, NLRP2, NLRP3, NLRP4, NLRP5, NLRP6, NLRP7, NLRP8, NLRP9, NLRP10, NLRP11, NLRP12
NOD-like_receptor
Part of the human immune system
pro-inflammatory cytokines, such as IL-1 and TNF-α. For example, NLRP11, NLRP5, NLRP2, and NLRP12 have been shown to inhibit different steps in the NF-κB pathway
NLRP
Protein domain
their ligand induces a conformational change. Some NLRs, such as NLRP1 and NLRP2, have a straightforward mechanism by which the receptor binds to a PAMP
Pyrin_domain
Protein domain
proteins containing this domain include: CIITA NAIP NLRC3, NLRC4, NLRC5 NLRP1, NLRP2, NLRP3, NLRP4, NLRP5, NLRP6, NLRP7, NLRP8, NLRP9, NLRP10, NLRP11, NLRP12
NACHT_domain
Cytosolic multiprotein complex that mediates the activation of Caspase 1
stimuli have been linked to the activation of NLRP1. NLRP1B in mice and NLRP2 in rats were found to be responsive to Bacillus anthracis lethal toxin.
Inflammasome
Overview of and topical guide to immunology
domain) NOD1 NOD2 NLRC3 NLRC4 (IPAF) NLRC5 NLRP (P for Pyrin domain) NLRP1 NLRP2 NLRP3 NLRP4 NLRP5 NLRP6 NLRP7 NLRP8 NLRP9 NLRP10 NLRP11 NLRP12 NLRP13 NLRP14
Outline_of_immunology
Q9NPP4 10590 NLRC5 HGNC:29933; Q86WI3 10591 NLRP1 HGNC:14374; Q9C000 10592 NLRP2 HGNC:22948; Q9NX02 10593 NLRP2B HGNC:29887; P0DMW2 10594 NLRP3 HGNC:16400;
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
NLRP2
NLRP2
NLRP2
NLRP2
Boy/Male
Bengali, Hindu, Indian, Marathi
Glorious; Beauty; Shining; Lustre
Boy/Male
German
Victorious ruler.
Boy/Male
Australian, French, Greek, Latin, Russian, Slavic
Royal; Kingly
Male
Ukrainian
, praise.
Female
English
Unisex pet form of Breton Yann, YANNIC means "God is gracious."
Girl/Female
Indian, Traditional
Beauty and Knowledge
Boy/Male
Hindu
Sages name
Boy/Male
Hindu, Indian, Punjabi, Sikh
Absorbed in Singing God's Praises
Girl/Female
American, British, English, Greek
Healer; With Healing Power
Boy/Male
Teutonic Russian
noble.
NLRP2
NLRP2
NLRP2
NLRP2
NLRP2