AI & ChatGPT searches , social queriess for NLRP1
Search references for NLRP1. Phrases containing NLRP1
See searches and references containing NLRP1!
Search references for NLRP1. Phrases containing NLRP1
See searches and references containing NLRP1!NLRP1
Human protein-coding gene
NLRP1 encodes NACHT, LRR, FIIND, CARD domain and PYD domains-containing protein 1 in humans. NLRP1 was the first protein shown to form an inflammasome
NLRP1
Cytosolic multiprotein complex that mediates the activation of Caspase 1
Lausanne, in 2002. In 2002, it was first reported by Martinon et al. that NLRP1 (NLR family PYD-containing 1) could assemble and oligomerize into a structure
Inflammasome
Group of innate immune system disorders
activation of an inflammasome complex nucleated by innate immune sensors such as NLRP1 (nucleotide-binding oligomerization domain (NOD)-like receptors), pyrin
Autoinflammatory_diseases
Skin condition where patches lose pigment
lupus erythematosus, and celiac disease. Among the inflammatory products of NLRP1 are caspase 1 and caspase 7, which activate the inflammatory cytokine interleukin-1β
Vitiligo
Class of proteins
NAIP NLRC (C for CARD): NOD1, NOD2, NLRC3, NLRC4, NLRC5 NLRP (P for PYD): NLRP1, NLRP2, NLRP3, NLRP4, NLRP5, NLRP6, NLRP7, NLRP8, NLRP9, NLRP10, NLRP11
NOD-like_receptor
Part of the human immune system
there are at least 14 different known NLRP genes in humans, which are named NLRP1 through NLRP14. The genes translate into proteins with differing lengths
NLRP
Protein-coding gene in humans
the NLRP1 protein and affects the level of activation of the NLRP1 inflammasome. This function involves binding to a complex of full-length NLRP1 and
DPP9
Polymer in bacterial cell walls
a mechanism triggered by increased mitochondrial membrane permeability. NLRP1 is also considered as a cytoplasmic sensor of peptidoglycan. It can sense
Peptidoglycan
Family of cell surface receptors
domain. There are 14 members of this protein subfamily in humans (called NLRP1 to NLRP14). NLRP3 and NLRP4 are responsible for the inflammasome activation
Pattern_recognition_receptor
Chinese American biochemist
revealed how the NLRP1 inflammasome protein is suppressed by the cellular protein DPP9 and is activated by the oligomeric UPA and CARD in NLRP1. During the
Hao_Wu_(biochemist)
American geneticist (born 1978)
have identified mutations responsible for progeroid syndromes in humans, NLRP1 inflammasome-related diseases, self-healing cancers and numerous diseases
Bruno_Reversade
Type of molecules within cells
TLR4, CD91 ATP P2X7, P2Y2 F-actin DNGR-1 Cyclophilin A CD147 Aβ TLR2, NLRP1, NLRP3, CD36, RAGE Nuclear Histones TLR2, TLR4 HMGB1 TLR2, TLR4, RAGE HMGN1
Damage-associated molecular pattern
Damage-associated_molecular_pattern
Protein domain
until their ligand induces a conformational change. Some NLRs, such as NLRP1 and NLRP2, have a straightforward mechanism by which the receptor binds
Pyrin_domain
Protein domain
proteins containing this domain include: CIITA NAIP NLRC3, NLRC4, NLRC5 NLRP1, NLRP2, NLRP3, NLRP4, NLRP5, NLRP6, NLRP7, NLRP8, NLRP9, NLRP10, NLRP11
NACHT_domain
syndrome, types 1, 2, 3, and 4 Neonatal onset multisystem inflammatory disease NLRP1 deficiency PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum
List of primary immunodeficiencies
List_of_primary_immunodeficiencies
Protein domain
protein containing a CARD (PYCARD) and NLR Family Pyrin Domain Containing 1 (NLRP1). Structurally, GBPs consist of two domains: a globular N- terminal domain
Guanylate-binding_protein
Enzyme found in humans
some cases, where the signaling proteins contain their own CARDs, like in NLRP1 and NLRC4, the CARD–CARD interaction is direct, meaning there is no adaptor
Caspase_1
Human protein and coding gene
endopeptidase activity Cellular component cytoplasm NLRP3 inflammasome complex NLRP1 inflammasome complex AIM2 inflammasome complex nucleolus endoplasmic reticulum
PYCARD
Metaphor used to visualize the processes of evolution
positive selection. The gene with the strongest positive selection was NLRP1, which has two haplotypes undergoing selective sweeps. The first haplotype
Evolutionary_landscape
Any type of cell death eliciting an immune response
cytosolic PRRs that are known to induce inflammasome formation are NLRP3, NLRP1, NLRC4, AIM2 and Pyrin. These proteins contain oligomerization NACHT domains
Immunogenic_cell_death
Species of single-celled organism
(2025-02-13). "Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation". EMBO Molecular Medicine. doi:10.1038/s44321-025-00197-4
Vulcanodinium_rugosum
Overview of and topical guide to immunology
CARD domain) NOD1 NOD2 NLRC3 NLRC4 (IPAF) NLRC5 NLRP (P for Pyrin domain) NLRP1 NLRP2 NLRP3 NLRP4 NLRP5 NLRP6 NLRP7 NLRP8 NLRP9 NLRP10 NLRP11 NLRP12 NLRP13
Outline_of_immunology
Q7RTR2 10589 NLRC4 HGNC:16412; Q9NPP4 10590 NLRC5 HGNC:29933; Q86WI3 10591 NLRP1 HGNC:14374; Q9C000 10592 NLRP2 HGNC:22948; Q9NX02 10593 NLRP2B HGNC:29887;
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
Chemical compound
(2025-02-13). "Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation". EMBO Molecular Medicine. doi:10.1038/s44321-025-00197-4
Portimine_A
Enzyme found in humans
with: APAF1 BIRC2, Baculoviral IAP repeat-containing protein 3, Caspase 8, NLRP1, and XIAP. The Proteolysis Map Caspase Caspase-3 Apoptosome Apaf-1 GRCh38:
Caspase-9
Mammalian protein found in Homo sapiens
has been shown to interact with: APIP, BCL2-like 1 Caspase-9, HSPA4, and NLRP1. GRCh38: Ensembl release 89: ENSG00000120868 – Ensembl, May 2017 GRCm38:
APAF1
Interaction motifs found in a wide array of proteins
[31][permanent dead link] NLRC5 It has also been called NOD27, NOD4, and CLR16.1 NLRP1: NLR family, pyrin domain containing 1 (previously called NALP1) [32][permanent
CARD_(domain)
NLRP1
NLRP1
NLRP1
NLRP1
Girl/Female
Greek English
Ariadne who aided Theseus to escape from the Cretan labyrinth.
Boy/Male
Indian
Devoted to God
Boy/Male
English American
Supplanter.
Boy/Male
Arabic, Muslim
Very Precious; Title of a King
Girl/Female
Anglo, Australian, Danish, Hebrew, Swedish
Little Warrior
Boy/Male
Hebrew
Happy. In the old Testament, Asher was one of Jacob's sons.
Boy/Male
African, American, Australian, British, Chinese, Christian, Danish, Dutch, English, Finnish, French, German, Greek, Irish, Jamaican, Latin, Swedish, Swiss
War-like; Mars; The Roman God of War; From the God Mars; Dedicated to Mars; Form of Marc; Roman God Mars; Defence; Of the Sea
Girl/Female
Tamil
Respectful
Surname or Lastname
English (Nottinghamshire)
English (Nottinghamshire) : nickname from Old French bon sire ‘good sir’, given either to a fine gentleman (perhaps ironically), or to someone who made frequent use of this term of address. Compare Bowser.
Boy/Male
Hindu
One of the kauravas
NLRP1
NLRP1
NLRP1
NLRP1
NLRP1