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MSH4

  • Chromosomal crossover
  • Cellular process

    3CRX​. The MSH4 and MSH5 proteins form a hetero-oligomeric structure (heterodimer) in yeast and humans. In the yeast Saccharomyces cerevisiae, MSH4 and MSH5

    Chromosomal crossover

    Chromosomal crossover

    Chromosomal_crossover

  • MSH4
  • Protein-coding gene in the species Homo sapiens

    protein homolog 4 is a protein that in humans is encoded by the MSH4 gene. The MSH4 and MSH5 proteins form a hetero-oligomeric structure (heterodimer)

    MSH4

    MSH4

    MSH4

  • Chromosome segregation
  • Biological process

    functional. The MSH4 and MSH5 proteins form a hetero-oligomeric structure (heterodimer) in S. cerevisiae and humans. In S. cerevisiae, MSH4 and MSH5 act

    Chromosome segregation

    Chromosome_segregation

  • Holliday junction
  • Branched nucleic acid structure

    pombe. The MSH4 and MSH5 proteins form a hetero-oligomeric structure (heterodimer) in yeast and humans. In the yeast Saccharomyces cerevisiae MSH4 and MSH5

    Holliday junction

    Holliday junction

    Holliday_junction

  • Neoplasm
  • Tumor or other abnormal growth of tissue

    13%-100% for the DNA repair genes BRCA1, WRN, FANCB, FANCF, MGMT, MLH1, MSH2, MSH4, ERCC1, XPF, NEIL1 and ATM. These epigenetic defects occurred in various

    Neoplasm

    Neoplasm

    Neoplasm

  • Zygotene
  • Second stage of prophase I in Meiosis

    between the non-sister chromatids. Key recombination proteins like MLH1/3 and MSH4/5 mark the sites of crossover formation. The number and positioning of these

    Zygotene

    Zygotene

  • MLH3
  • Protein-coding gene in humans

    yeast and, by inference, in mammals. MLH3 has been shown to interact with MSH4. GRCh38: Ensembl release 89: ENSG00000119684 – Ensembl, May 2017 GRCm38:

    MLH3

    MLH3

    MLH3

  • Melanotan II
  • Drug that never made it to the market

    Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 Ac-cyclo[Nle4, Asp5,D-Phe7, Lys10]α-MSH4–10-NH2 N-Acetyl-L-norleucyl-L-α-aspartyl-L-histidyl-D-phenylalanyl-L-arg

    Melanotan II

    Melanotan II

    Melanotan_II

  • MSH
  • Topics referred to by the same term

    gland, and related to skin pigmentation DNA mismatch repair genes: MSH2 MSH3 MSH4 MSH5 MSH6 Multiple system atrophy Mycothiol, an unusual thiol that is found

    MSH

    MSH

  • Genome instability
  • High frequency of mutations within the genome of a cellular lineage

    epigenetic defects in genes BRCA1, WRN, FANCB, FANCF, MGMT, MLH1, MSH2, MSH4, ERCC1, XPF, NEIL1 and ATM located in cancers including breast, ovarian,

    Genome instability

    Genome instability

    Genome_instability

  • MSH5
  • Protein-coding gene in the species Homo sapiens

    rather than the non-cross over option. MSH5 has been shown to interact with MSH4. ENSG00000235569, ENSG00000204410, ENSG00000230293, ENSG00000235222, ENSG00000237333

    MSH5

    MSH5

    MSH5

  • MLH1
  • Protein-coding gene in humans

    been shown to interact with: Bloom syndrome protein Exonuclease 1, MBD4, MSH4, Myc, and PMS2. Mismatch repair#MutH: an endonuclease present in E. coli

    MLH1

    MLH1

    MLH1

  • List of human protein-coding genes 5
  • HGNC:14907; A6NI15 9901 MSH2 HGNC:7325; P43246 9902 MSH3 HGNC:7326; P20585 9903 MSH4 HGNC:7327; O15457 9904 MSH5 HGNC:7328; O43196 9905 MSH6 HGNC:7329; P52701

    List of human protein-coding genes 5

    List_of_human_protein-coding_genes_5

  • MSH2
  • Protein-coding gene in the species Homo sapiens

    1999). "hMSH5: a human MutS homologue that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis". Cancer Res. 59 (4): 816–22. PMID 10029069

    MSH2

    MSH2

    MSH2

  • GPS2 (gene)
  • Protein-coding gene in the species Homo sapiens

    PMID 15159402. Lee TH, Yi W, Griswold MD, Zhu F, Her C (Jan 2006). "Formation of hMSH4-hMSH5 heterocomplex is a prerequisite for subsequent GPS2 recruitment". DNA

    GPS2 (gene)

    GPS2 (gene)

    GPS2_(gene)

  • MSH6
  • Protein-coding gene in Homo sapiens

    1999). "hMSH5: a human MutS homologue that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis". Cancer Research. 59 (4): 816–22

    MSH6

    MSH6

    MSH6

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Online names & meanings

  • MYRNA
  • Female

    English

    MYRNA

    Anglicized form of Irish Gaelic Muirne, MYRNA means "obstinacy, rebelliousness" or "their rebellion."

  • Bhadanta
  • Boy/Male

    Buddhist, Indian, Sanskrit

    Bhadanta

    Term of Respect Applied to a Buddhist Mendicant

  • Fath |
  • Boy/Male

    Muslim

    Fath |

    Victory

  • Jiri
  • Boy/Male

    Greek

    Jiri

    Farmer.

  • Findlay
  • Boy/Male

    Gaelic Irish

    Findlay

    Small blond soldier.

  • Ellisif
  • Girl/Female

    Norse

    Ellisif

    consecrated to God.

  • Reeham |
  • Girl/Female

    Muslim

    Reeham |

    Little, Light rain, Drizzle, Mercy

  • Rudradeva
  • Boy/Male

    Indian

    Rudradeva

    Lord Shiva

  • Wixon
  • Surname or Lastname

    English

    Wixon

    English : variant spelling of Wickson.

  • JULYAN
  • Male

    English

    JULYAN

    English form of Roman Latin Julian, JULYAN means "descended from Jupiter (Jove)."

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MSH4

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MSH4