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MLL4

  • MLL4
  • Protein-coding gene in the species Homo sapiens

    Myeloid/lymphoid or mixed-lineage leukemia 4, also known as MLL4, is a human gene. This gene encodes a protein which contains multiple domains including

    MLL4

    MLL4

    MLL4

  • KMT2D
  • Protein-coding gene in humans

    Histone-lysine N-methyltransferase 2D (KMT2D), also known as MLL4 and sometimes MLL2 in humans and Mll4 in mice, is a major mammalian histone H3 lysine 4 (H3K4)

    KMT2D

    KMT2D

    KMT2D

  • H3K4me1
  • Histone methylation on tail of histone H3 associated with enhancers

    identity. Enhancers are primed by histone H3K4 mono-/di-methyltransferase MLL4 and then are activated by histone H3K27 acetyltransferase p300. H3K4me1 fine-tunes

    H3K4me1

    H3K4me1

  • SOX9
  • Transcription factor gene of the SOX family

    shown to interact with steroidogenic factor 1, MED12, MAF, SWI/SNF, MLL3 and MLL4. Loss of function mutations with Sox9 can lead to campomelic dysplasia (CD)

    SOX9

    SOX9

    SOX9

  • HOXC10
  • Protein-coding gene in the species Homo sapiens

    transcriptionally regulated by estrogen via involvement of histone methylases MLL3 and MLL4. Methylation of the estrogen-repressed gene HOXC10 in breast cancer determines

    HOXC10

    HOXC10

    HOXC10

  • Lysine-specific demethylase 6A
  • Protein-coding gene in humans

    Cho YW, Hong T, Hong S, et al. (2007). "PTIP Associates with MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase Complex". J. Biol. Chem

    Lysine-specific demethylase 6A

    Lysine-specific demethylase 6A

    Lysine-specific_demethylase_6A

  • Histone methyltransferase
  • Class of enzymes

    activity include: ASH1L DOT1L EHMT1, EHMT2, EZH1, EZH2 MLL, MLL2, MLL3, MLL4, MLL5 NSD1 PRDM2 SET, SETBP1, SETD1A, SETD1B, SETD2, SETD3, SETD4, SETD5

    Histone methyltransferase

    Histone methyltransferase

    Histone_methyltransferase

  • KMT2C
  • Protein-coding gene in the species Homo sapiens

    Guo H, Yu H, Kim D, et al. (July 2007). "PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex". The Journal of

    KMT2C

    KMT2C

    KMT2C

  • Pioneer factor
  • Transcription factor

    of DNA methylation. SOX9 recruits histone modification enzymes MLL3 and MLL4 to deposit H3K4me1 prior to the opening of enhancers in developing hair follicle

    Pioneer factor

    Pioneer_factor

  • C19Orf81
  • Human protein and gene

    cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4). Human molecular genetics, 31(21), 3715–3728. https://doi.org/10.1093/hmg/ddac121

    C19Orf81

    C19Orf81

    C19Orf81

  • PAXIP1
  • Protein-coding gene in the species Homo sapiens

    GR, Copeland TD, Kalkum M, Ge K (2007). "PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex". J. Biol. Chem

    PAXIP1

    PAXIP1

    PAXIP1

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Online names & meanings

  • Jomon
  • Boy/Male

    Indian, Malayalam

    Jomon

    Small Boy

  • Bankebihari
  • Boy/Male

    Gujarati, Hindu, Indian, Kannada, Malayalam, Marathi, Mythological, Telugu

    Bankebihari

    Lord Krishna

  • Aakriti
  • Girl/Female

    Hindu, Indian, Kannada, Malayalam, Marathi, Tamil, Telugu, Traditional

    Aakriti

    Shape; Form; Design; Diagram

  • Manara
  • Girl/Female

    Arabic

    Manara

    Light; To Illuminate

  • Simona, Simone
  • Girl/Female

    Christian & English(British/American/Australian)

    Simona, Simone

    It is Heard

  • Vyaapti | வ்யாபதீ
  • Girl/Female

    Tamil

    Vyaapti | வ்யாபதீ

    Achievement, Omnipresence, Permeation

  • Heckle
  • Surname or Lastname

    English (Cheshire)

    Heckle

    English (Cheshire) : from Middle English hekel ‘heckle’, an implement for combing or scutching flax or hemp for spinning, hence a metonymic occupational name for someone who made or used heckles.French (Alsace; Hecklé) : from a diminutive of German Heck 2.

  • Dilawar | دیلاور
  • Boy/Male

    Muslim

    Dilawar | دیلاور

    Brave

  • Mueez |
  • Boy/Male

    Muslim

    Mueez |

    One who gives protection, The giver of might and glory

  • Rahila
  • Girl/Female

    Indian

    Rahila

    One who travels

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MLL4

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