AI & ChatGPT searches , social queriess for MEF2C
Search references for MEF2C. Phrases containing MEF2C
See searches and references containing MEF2C!
Search references for MEF2C. Phrases containing MEF2C
See searches and references containing MEF2C!MEF2C
Protein-coding gene in the species Homo sapiens
factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene. MEF2C is a transcription factor in the Mef2 family. The gene is located
MEF2C
Protein family
versions of the Mef2 gene (human versions are denoted as MEF2A, MEF2B, MEF2C, and MEF2D), all expressed in distinct but overlapping patterns during embryogenesis
Mef2
Non-coding RNA in the species Homo sapiens
MEF2C antisense RNA 1 is a protein that in humans is encoded by the MEF2C-AS1 gene. GRCh38: Ensembl release 89: ENSG00000248309 – Ensembl, May 2017 "Human
Mef2c_antisense_rna_1
Symbol of various advocacy campaigns
and sexual assault (teal & purple), hypotonia (lime green, blue, & pink), MEF2C haploinsufficiency syndrome (lime green & black, with DNA strand), medullary
Green_ribbon
Human chromosome
transcription factor AF4/FMR2 family, member 4 MEF2C: Myocyte-specific enhancer factor 2C MEF2C-AS1: encoding protein MEF2C antisense RNA 1 MGAT1: Mannosyl (alpha-1
Chromosome_5
Protein-coding gene in the species Homo sapiens
is a transcription factor part of the MEF2 gene family including MEF2A, MEF2C, and MEF2D. However, MEF2B is distant from the other three branches of MEF2
MEF2B
Pluripotent stem cell generated directly from a somatic cell
cardiomyocytes that spontaneously began beating. Cardiomyocytes expressed TnTc, MEF2C, MYL2A, MYHCβ, and NKX2.5. Stem cell-associated genes were downregulated
Induced_pluripotent_stem_cell
Mammalian protein found in Homo sapiens
cooperates with MyoD at inducing the transcriptional activity of MEF2C (by displacing HDAC4 from MEF2C); moreover IFRD1 also represses the transcriptional activity
MyoD
Investigational drug
J, Yan C, He W, Wang M, Liu J (December 2020). "Inhibition against p38/MEF2C pathway by Pamapimod protects osteoarthritis chondrocytes hypertrophy".
Pamapimod
Formation of muscular tissue, particularly during embryonic development
Mef2 and the twist transcription factor. Studies have shown knockouts for Mef2C in mice lead to muscle defects in cardiac and smooth muscle development
Myogenesis
Protein-coding gene in the species Homo sapiens
ESR1, FEN1, GPS2, HIF1A, HNF1A, HNRPU, ING4, ING5, IRF2, LEF1, MAF, MAML1, MEF2C, MEF2D, MYBL2, Mdm2, MyoD, MEF2A, NCOA6, NFATC2, NPAS2, P53, PAX6, PCNA
EP300
Health issue in Japan
contributor to type 2 diabetes in Japanese populations. These genes are MEF2C, TMEM161B, CEP120, PRDM6, STEAP1, ZNF804B, ZNRF3, PRIM1, IRF2BPL, LRRC74A
Diabetes_in_Japan
KL, McKercher SR, Zaremba JD, et al. (July 2008). "Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in
Heritability_of_autism
Enzyme catalyzing transfer of phosphate groups onto specific substrates
transcriptional targets include ATF-2, Chop, c-Jun, c-Myc, DPC4, Elk-1, Ets1, Max, MEF2C, NFAT4, Sap1a, STATs, Tal, p53, CREB, and Myc. MAPK can also regulate translation
Kinase
British neuroscientist
"RePORT ⟩ RePORTER". "RePORT ⟩ RePORTER". "RePORT ⟩ RePORTER". "Investigating MEF2C Transcription Factor as a Therapeutic Target to Reprogram Pathological Microglial
Alison_Goate
Protein found in humans
This protein does not bind DNA directly but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and
HDAC4
Regrowth of lost tissues or organs
cardiomyocyte-like cells. This was done using three transcription factors: GATA4, Mef2c, and Tbx5. Cardiac fibroblasts make up more than half of all heart cells
Regeneration_in_humans
ENSG00000213999 MADS box Known motif – High-throughput in vitro [518] TGTTACCATAWHBGG MEF2C ENSG00000081189 MADS box Known motif – High-throughput in vitro [519] TWCTAWAAATAG
List of human transcription factors
List_of_human_transcription_factors
regulates serum-induced early gene expression through transcription factor MEF2C". The EMBO Journal. 16 (23): 7054–7066. doi:10.1093/emboj/16.23.7054. PMC 1170308
RAF_kinase
Protein-coding gene in the species Homo sapiens
SAFB and Hsp27. It also has been reported to interact with mRNAs such as Mef2c mRNA. GRCh38: Ensembl release 89: ENSG00000138668 – Ensembl, May 2017 GRCm38:
HNRPD
Protein-coding gene in the species Homo sapiens
inducing the transcriptional activity of MEF2C. This relies on the ability of IFRD1 to bind selectively MEF2C, thus inhibiting its interaction with HDAC4
IFRD1
leading to differentiation. It also increases the activity of MEF2, mainly MEF2C, in N2a cells. α-lipoic acid (LA) mainly causes N2a differentiation through
N2a_cell
Protein-coding gene in the species Homo sapiens
defect syndrome (HLTRS). SOX18 has been shown to interact with: MEF2C RBPJ SOX genes GRCh38: Ensembl release 89: ENSG00000203883 – Ensembl, May
SOX18
Protein-coding gene in the species Homo sapiens
green, spans amino acids 513-556. Domains for binding of protein partners, MEF2C and HCAC5, are shown in magenta (spanning amino acids 12-27) and orange
Myocardin
Protein family
heterodimers and multimeric protein complexes. Mef2 family: MEF2A, MEF2B, MEF2C, MEF2D SRF Schwarz-Sommer Z, Huijser P, Nacken W, Saedler H, Sommer H (November
MADS-box
Professor of neuroimmunology
Marco; Villeda, Saul; Citri, Ami; Amit, Ido; Schwartz, Michal (2017). "Mef2C restrains microglial inflammatory response and is lost in brain ageing in
Michal_Schwartz
Pharmaceutical compound
K, Meijer MT, Cordo' V, Hagelaar R, Yang W, Yu J, et al. (July 2022). "MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus"
YKL-05-099
Embryonic carcinoma cell line
GATA-4, MEF2c, Msx-1, Nkx2.5, MHox, Msx-2 and MLP are found to change during differentiation. Reports have shown that GATA-4, NKx2.5 and MEF2c were all
P19_cell
Protein-coding gene in humans
associated with the risk of multiple sclerosis, is responsible for appearance of MEF2C-binding site resulted in reduced CXCR5 gene promoter activity in B-cells
CXCR5
Protein-coding gene in the species Homo sapiens
CEBPB, COL1A1, E2F1, FOSL1, GABPA, HDAC1, HDAC2, HMGA1, HCFC1, HTT, KLF6, MEF2C, MEF2D, MSX1, Myogenin, POU2F1, PPP1R13L, PSMC5, PML, RELA, SMAD3, SUMO1
Transcription_factor_Sp1
Scientist and physician (b. 1975)
Craig; de Stanchina, Elisa; Gonen, Mithat; Seshan, Venkatraman (2018). "MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid
Alex_Kentsis
Protein-coding gene in the species Homo sapiens
expression of cardiac specific genes Mesp1, Myl7, Myl2, Myocardin, Nkx2.5 and Mef2c. Eomesodermin/Tbr2 is highly expressed in CD8+ T cells, but not CD4+ T cells
Eomesodermin
Protein-coding gene in the species Homo sapiens
been shown to interact with: C-Raf, Gap junction protein, alpha 1 MAP2K5, MEF2C, MEF2D, PTPRR, SGK, and YWHAB. XMD8-92 was one of the first described ERK5
MAPK7
Protein family
transduction pathways as well, including: muscle differentiation and myopathies (MEF2C), tumour suppressor pathway (p53) and colon carcinoma survival (beta-catenin)
MamL-1_domain
Protein-coding gene in the species Homo sapiens
regulates serum-induced early gene expression through transcription factor MEF2C". The EMBO Journal. 16 (23): 7054–66. doi:10.1093/emboj/16.23.7054. PMC 1170308
MAP2K5
Protein-coding gene in the species Homo sapiens
their transcriptional activity, including MyoD, C/EBP, Reptin, p53, MEF2D, MEF2C and MTA1. Furthermore, G9A/GLP are able to methylate non-histone proteins
EHMT1
HGNC:25926; Q5VYS4 9437 MEF2A HGNC:6993; Q02078 9438 MEF2B HGNC:6995; Q02080 9439 MEF2C HGNC:6996; Q06413 9440 MEF2D HGNC:6997; Q14814 9441 MEFV HGNC:6998; O15553
List of human protein-coding genes 5
List_of_human_protein-coding_genes_5
element, and a MEF2 site, and muscle transcription factors myogenin and MEF2C stimulate RGMc promoter function in non-muscle cells. As these elements
Hemojuvelin
activates muscle-specific gene expression by regulating expression of MAML1 and MEF2C via antagonizing miR-133 and miR-135. Whether Linc-MD1 regulates miRNA activity
Competing_endogenous_RNA
RNA family
pathway. SREBP-1c mediates MEF2C downregulation through a mechanism that remains to be determined. As a consequence of lower MEF2C binding on their enhancer
Mir-133 microRNA precursor family
Mir-133_microRNA_precursor_family
Non-coding RNA in the species Homo sapiens
targets include: ANP32A, BTG2, Bcl2, P12/CDK2AP1, HNRPK, IL-12p35, JAG1, MEF2C, hMSH2, PDCD4, PTEN, RECK, RhoB, SMARCA4, TGFBRII, SPRY1, SPRY2, TP63, and
MIRN21
deletion syndrome; 606232; SHANK3 Chromosome 5q14.3 deletion syndrome; 613443; MEF2C Chrondrodysplasia, acromesomelic, with genital anomalies; 609441; BMPR1B
List_of_OMIM_disorder_codes
Enzymes that catalyze acyl group transfer from acetyl-CoA to histones
TFIIF. Other substrates include the transcription factors Sp1, KLF5, FOXO1, MEF2C, SRY, GATA-4, and HNF-6, HMG-B2, STAT3, the androgen and estrogen (α) receptors
Histone_acetyltransferase
Protein-coding gene in the species Homo sapiens
PMID 15489334. Kobarg CB, Kobarg J, Crosara-Alberto DP, et al. (2005). "MEF2C DNA-binding activity is inhibited through its interaction with the regulatory
HABP4
Discarding of garden waste at an inappropriate location
Cavalheiro, E.; Scorza, F. (2008). "Myocyte-specific enhancer binding factor 2C (MEF2C) expression in the dentate gyrus during development and after pilocarpine-induced
Garden_waste_dumping
Protein-coding gene in the species Homo sapiens
kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest
MAPK14
Protein-coding gene in the species Mus musculus
sites (DNA-protein interaction) predicted include one binding site for MEF2C a monocyte-specific enhancement factor that is involved in muscle-cell regulation
DMAC1
MEF2C
MEF2C
MEF2C
MEF2C
Boy/Male
Muslim/Islamic
Slave of the Gracious
Girl/Female
Hindu
Beloved, Grace, Truth
Boy/Male
Hindu, Indian
Sacred; Belonging to Benaras
Girl/Female
Greek, Gujarati, Hindu, Indian, Jain, Kannada, Malayalam, Marathi, Sindhi, Tamil, Telugu
A Bud; Name of a Godess Kalli
Surname or Lastname
English (Kent)
English (Kent) : habitational name from Maxted Street in Kent.
Boy/Male
Hindu, Indian, Traditional
Water
Boy/Male
Native American
Sage.
Girl/Female
African, Arabic, French
White
Boy/Male
Hindu
The supreme spirit
Boy/Male
Muslim
The gatherer
MEF2C
MEF2C
MEF2C
MEF2C
MEF2C