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Topics referred to by the same term
Leader sequence may refer to: Leader sequence (mRNA), a sequence of mRNA Leading strand, in DNA replication This disambiguation page lists articles associated
Leader_sequence
Sequence of amino acids
pelB leader sequence is a sequence of amino acids which, when attached to a protein, directs the protein to the bacterial periplasm, where the sequence is
PelB_leader_sequence
Short peptide present at N-terminal of newly synthesized proteins
referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short
Signal_peptide
Region of a messenger RNA
The five prime untranslated region (5′ UTR), or leader sequence, transcript leader, or leader RNA, is the region of a messenger RNA (mRNA) that is directly
Five prime untranslated region
Five_prime_untranslated_region
Family of DNA sequences found in prokaryotic organisms
repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. Each sequence within an individual prokaryotic
CRISPR
Family of viruses
regions include: A 3' leader sequence, 50 nucleotides in length, which acts as a transcriptional promoter. A 5' trailer sequence, 50 to 161 nucleotides
Paramyxoviridae
RNA family
The Tryptophan operon leader is an RNA element found at the 5′ of some bacterial tryptophan operons. The leader sequence can form two different structures
Tryptophan_operon_leader
Phylum of viruses
producing the antigenome. At the leader sequence, RdRp synthesizes a 5'-end (usually pronounced "five prime end") triphosphate-leader RNA and either, in the case
Negative-strand_RNA_virus
Set of biochemical processes
distinct block of the leader sequence, called block 1: Met-Thr-Arg-Val-Gln-Phe-Lys-His-His-His-His-His-His-His-Pro-Asp This leader sequence is important for
Amino_acid_synthesis
biosynthesis. The PyrC leader regulates expression of PyrC. Translation initiation can occur at four different sites within this leader sequence, under high CTP
PyrC_leader
Regulatory mechanism
corresponds to the leader sequence of mRNA. During attenuation, the ribosome becomes stalled (delayed) in the attenuator region in the mRNA leader. Depending
Attenuator_(genetics)
Non-coding regions on either end of mRNA
each side of a coding sequence on a strand of mRNA. If it is found on the 5' side, it is called the 5' UTR (or leader sequence), or if it is found on
Untranslated_region
RNA family
attenuation. In each a leader sequence of 150–200 bp is found upstream of the first gene in the operon. This leader sequence can assume two different
Histidine_operon_leader
Maturation process joining exons from different pre-mRNAs into a mature mRNA
viability. In Ascaris, the spliced leader sequence is needed to the RNA gene can be transcribed. The Spliced leader sequence may be responsible for initiation
Trans-splicing
PyrD leader and pyrimidine biosynthesis
The PyrD leader regulates expression of PyrD. Translation initiation can occur at more than one different site within this leader sequence, under high
PyrD_leader
Subfamily of eosinophil chemotactic proteins
leader sequences eotaxin and the MPC family provide evidence that there might be an additional role that these leader sequences may have. The leader sequences
Eotaxin
RNA family
The Leucine operon leader is an RNA element found upstream of the first gene in the Leucine biosynthetic operon. The leader sequence can assume two different
Leucine_operon_leader
Virus classification system made by David Baltimore
the viral RdRp binding to a leader sequence on the 3′-end of the genome, transcribing a 5′ triphosphate-leader RNA sequence, then stopping and restarting
Baltimore_classification
sequences. Unlike SAGE, detection and purification of transcripts from the 5’ end of the messenger RNA require the presence of a trans-spliced leader
Trans-Spliced Exon Coupled RNA End Determination
Trans-Spliced_Exon_Coupled_RNA_End_Determination
Mammalian protein found in Homo sapiens
length. Upon entry to the mitochondria, the 32 amino acid mitochondrial leader sequence at the N-terminus of the protein is cleaved, forming the fully processed
Methylmalonyl-CoA_mutase
alphabetical order. A typical entry reports information in the following sequence: Name, age, country of citizenship at birth, subsequent nationality (if
Deaths_in_2026
RNA family
operon leader is an RNA element. Threonine is one of at least 6 amino acid operons are known to be regulated by attenuation. In each a leader sequence of
Threonine_operon_leader
Lac operon Lagging strand Lambda phage Lateral inhibition Leader peptide gene Leader sequence (mRNA) Leading strand Leaky mutant Lesion Lethal gene Leu
Index_of_genetics_articles
Class of enzymes
precursor tRNA with flanking sequences and was the first to characterize RNase P and its activity in processing of the 5' leader sequence of precursor tRNA. Its
Ribonuclease_P
Species of virus
highly structured 600 nucleotide long leader sequence with six to eight short open reading frames (ORFs). This leader is followed by seven tightly arranged
Cauliflower_mosaic_virus
RNA element
Usually found in gram-positive bacteria, the T box leader sequence is an RNA element that controls gene expression through the regulation of translation
T-box_leader
Species of virus
as the transcriptional promoter. The 5’ trailer sequence (at the opposite end of the leader sequence) is between 50 and 161 nucleotides in length. There
Bat_mumps_virus
Number theory related to prime numbers
"Chebyshev Bias". MathWorld. (sequence A007350 in the OEIS) (where prime race 4n+1 versus 4n+3 changes leader) (sequence A007352 in the OEIS) (where prime
Chebyshev's_bias
RNA family
coupled. The leader sequence of the repA mRNA contains two complementary sequences of 8 bases. Base-pairing between these two sequences forms a pseudoknot
Regulatory region of repBA gene
Regulatory_region_of_repBA_gene
Database of nematode genomics
and are manually curated using evidence from the SL2 trans-spliced leader sequence sites. There are several classes of non-coding RNA gene classes in
WormBase
RNA family
ylbH gene in B. subtilis and related low GC Gram-positive bacteria. Leader sequence Riboswitch Barrick JE, Corbino KA, Winkler WC, Nahvi A, Mandal M, Collins
YlbH_leader
Order of positive-sense, single-stranded RNA viruses
needed] Most, but not all, nidovirus subgenomic RNAs contain a 5′ leader sequence derived from the 5′ end of the genomic RNA. The frameshift that generates
Nidovirales
Mammalian protein found in humans
intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations
24-Dehydrocholesterol reductase
24-Dehydrocholesterol_reductase
RNA family
the TAS of the IBV D-RNA contained a consensus sequence that can accept the switched leader sequence and can also be involved in the expression of mRNA
Infectious bronchitis virus D-RNA
Infectious_bronchitis_virus_D-RNA
Protein found in humans
of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound
Tafazzin
Family of viruses
phage have a "leader sequence" on the gene 8 protein to promote membrane insertion, but others do not seem to need the leader sequence. The two ends of
Filamentous_bacteriophage
Type of virus that infects the domain of unicellular, prokaryotic organisms or Archaea
sequenced archaea possess at least one CRISPR-Cas locus in their genome. These loci contain a leader sequence, alternating short identical sequences termed
Archaeal_virus
1977 tactical board wargame
semi-simultaneous system of play developed in the mid-1970s can be seen in Squad Leader's sequence of play. Each turn consists of two player turns, each of which have
Squad_Leader
Protein used as a biomarker of kidney function
in semen, followed by breastmilk, tears and saliva. The hydrophobic leader sequence indicates that the protein is normally secreted. There are three polymorphisms
Cystatin_C
Mechanism in eukaryotic translation
at a non-AUG codon. Eukaryotic genes containing consistent G-C rich leader sequences are frequently observed performing this mechanism. It is hypothesized
Leaky_scanning
Adenoviral vector for vaccines
Ankara (MVA) vector encoding the LS2 fused to the C-terminal end of the leader sequence of tPA. The trial reached the phase I/IIa. There are also investigation
ChAdOx1
Russian political joke
Nicholas I's son Alexander II formed the first "bald–hairy" pair of the sequence with his father. In Soviet times (for rulers after Lenin), the rule applies
Bald–hairy
Computer scientist (born 1986)
several major contributions to the field of deep learning, including sequence-to-sequence learning, reasoning models, GPT models, and contributions to CLIP
Ilya_Sutskever
Species of bacteria
frames, including many housekeeping genes. About 50% of the 5′ UTRs (leader sequences) are 20–40 nucleotides (nt) in length and support the AAGGag motif
Helicobacter_pylori
Aspect of molecular biology
~600 nucleotide leader sequence which contains 7-9 short open reading frames (sORFs) depending on the strain. This long leader sequence has the potential
Ribosome_shunting
1964 spy film by Guy Hamilton
extensive use of technology and gadgets by Bond, an extensive pre-credits sequence that stood largely alone from the main plot, multiple foreign locales and
Goldfinger_(film)
Species of virus
polyprotein. 5' of the central coding sequence is a 1144-nucleotide nontranslated leader sequence (UTR). 3' coding sequence is a 317-nucleotide nontranslated
Deformed_wing_virus
Type of protein
1988). "Modulation of folding pathways of exported proteins by the leader sequence". Science. 239 (4843): 1033–5. Bibcode:1988Sci...239.1033P. doi:10
Maltose-binding_protein
Indian actress and former Chief Minister of Tamil Nadu (1948–2016)
director Aroor Pattabhi asked Sandhya if Jayalalithaa could act in the dance sequence. Sandhya agreed and Jayalalithaa was swiftly dressed up as Parvathy and
J._Jayalalithaa
2003 American film by Quentin Tarantino
former Deadly Viper who has become the leader of the yakuza in Tokyo. Ai Maeda as O-Ren Ishii (anime sequence) (voice) Vivica A. Fox as Vernita Green
Kill_Bill:_Volume_1
Biological technique to evolve proteins using bacteriophages
available online. Directed evolution protein–protein interactions PelB leader sequence Competing techniques: Two-hybrid system mRNA display Ribosome display
Phage_display
GPE: a protein containing 78 amino acids with a 19 amino acid long leader sequence. GPE has yet to be expressed but it is known to be able to recombine
GYPE
Fantasy comedy TV series (2019–2026)
five-week shoot between January and February 2025. Good Omens' opening title sequence, created by the London-based Peter Anderson Studio, features music by David
Good_Omens_(TV_series)
RNA element
expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus". Nucleic Acids Research. 19 (16): 4485–4490. doi:10
Internal_ribosome_entry_site
Proteinaceous hair-like appendage on the surface of bacteria
distinct archaeal type IV pili structures formed by proteins with identical sequence". Nature Communications. 15 (1): 5049. Bibcode:2024NatCo..15.5049L. doi:10
Pilus
Protein family
acyl residues (aas) long with its leader sequence, is monomeric, and binds a single Hg2+ ion. Hg2+ is bound to a sequence GMTCXXC found in metallochaperones
Mercury_transporter
Message delivery protocol in a network
integer sequence number. The sequence numbers reset to 1 as each new view is defined (via a special kind of multicast, as explained below). A leader "talks
Gbcast
establishing the correct sequence of the amino acid residues in the EPO gene which coded for human EPO and its leader sequence. The Amgen patent addressed
Kirin-Amgen Inc v Hoechst Marion Roussel Ltd
Kirin-Amgen_Inc_v_Hoechst_Marion_Roussel_Ltd
List of characters appearing in the Marvel Cinematic Universe
also References Ajak (portrayed by Salma Hayek) is the wise and spiritual leader of the Eternals, who possesses healing abilities and functions as the "bridge"
Characters of the Marvel Cinematic Universe: A–L
Characters_of_the_Marvel_Cinematic_Universe:_A–L
Enzyme
reductase gene: determination of correct cDNA sequence and identification of a mitochondrial leader sequence". Biochem. Biophys. Res. Commun. 269 (2): 366–8
Glutathione_reductase
Animated superhero television series
has received widespread critical acclaim, with praise for its action sequences, story, voice performances (particularly Yeun, Oh, and Simmons), faithfulness
Invincible_(TV_series)
Species of virus
(VPg) which is said to act as an enhancer of transcription. The 5’-leader sequence has an internal ribosome entry site (IRES) and cap-independent translation
Potato_virus_Y
spacers area always added at the beginning of the CRISPR sequence next to the leader sequence. This directing of integration by IHF ensures that spacers
Bacterial_DNA_binding_protein
Protein-coding gene in the species Homo sapiens
structure is a single-chain molecule made of 469 amino acids, with the leader sequence consisting of 27-amino acids. Every properdin monomer is made of six
Properdin
Controlled release of substances by cells or tissues
process begins as a leader sequence on the protein to be secreted is recognized by HlyA and binds HlyB on the membrane. This signal sequence is extremely specific
Secretion
Class of enzyme that catalyzes the degradation of RNA
the same way as an enzyme. One of its functions is to cleave off a leader sequence from the 5' end of one stranded pre-tRNA. RNase P is one of two known
Ribonuclease
List of characters appearing in the Marvel Cinematic Universe
Nathan Fillion had appeared on movie posters as the character in a cut sequence from Guardians of the Galaxy Vol. 2. James Gunn, the director of that film
Characters of the Marvel Cinematic Universe: M–Z
Characters_of_the_Marvel_Cinematic_Universe:_M–Z
Country in Eastern Europe and North Asia
Hublin JJ, Reich D, Kelso J, Viola TB, Pääbo S (23 October 2014). "Genome sequence of a 45,000-year-old modern human from western Siberia". Nature. 514 (7523):
Russia
Mammalian protein found in Homo sapiens
"Isolation of a human ceruloplasmin cDNA clone that includes the N-terminal leader sequence". FEBS Letters. 203 (2): 185–90. Bibcode:1986FEBSL.203..185M. doi:10
Ceruloplasmin
Enzyme
catalytic ability. This protein also possesses an N-terminal mitochondrial leader sequence which targets it to the mitochondrial matrix, where it converts
SOD2
Protein family
produce the active enzyme. In order to expose the nickel-binding hook, a leader sequence must be enzymatically cleaved off the N-terminus. Wuerges J, Lee JW
Nickel_superoxide_dismutase
President of France since 2017
from the original on 5 August 2020. Retrieved 26 July 2023. "La folle séquence médiatique d'Emmanuel Macron – Le Lab Europe 1" (in French). Archived from
Emmanuel_Macron
Cis-acting element
alpha-proteobacterial genomes for conserved sequence motifs in operon leaders. In the majority of species analysed it is located in the leader of an operon containing the
SpeF_leader
Species of virus
Gunzburg, Walter H.; Salmons, Brian; Indik, Stanislav (2012). "The 5′ leader sequence of mouse mammary tumor virus enhances expression of the envelope and
Mouse_mammary_tumor_virus
2013 Indian film by A. L. Vijay
Thalaivaa (transl. The Leader) is a 2013 Indian Tamil-language action thriller film directed by A. L. Vijay (credited as Vijay) and produced by Vendhar
Thalaivaa
Group of antimicrobial peptides
first exon encodes for a hydrophobic leader sequence (removed after translation) and the cysteine-rich sequence (the mature peptide). The disulfide linkages
Defensin
American microbiologist
small RNA helps to translate the RpoS factor by binding to the RpoS leader sequence. Elected to the National Academy of Sciences in 1998. Elected to the
Susan_Gottesman
Species of virus
3’ leader sequence and a 5’ trailer sequence typically made up of 40 or 41 nt. Feline morbillivirus, however, breaks the typical 5’ trailer sequence rule
Feline_morbillivirus
Prepro-GAOX (galactose oxidase with signal sequence) is processed twice by proteolytic cleavage in the leader sequence to form the mature GAOX peptide (pro-GAOX)
Galactose_oxidase
Founder of Islam (c. 570–632)
570 CE – 8 June 632 CE) was an Arab religious, military, and political leader, and the founder of Islam. According to Islam, he was the final prophet
Muhammad
Code sequence with no branches except at entry and exit
In compiler construction, a basic block is a straight-line code sequence with no branches in except to the entry and no branches out except at the exit
Basic_block
Bacterial non-coding RNA regulatory element
is a bacterial non-coding RNA regulatory element found in the rnc leader sequence. The rnc operon is negatively auto-regulated by transcript stability
RncO
Protein-coding gene in the species Homo sapiens
1990). "Sequence of the cDNA and 5'-flanking region for human acid alpha-glucosidase, detection of an intron in the 5' untranslated leader sequence, definition
Acid_alpha-glucosidase
both activate RpoS translation by base pairing to a region in the leader sequence of the RpoS mRNA and disrupting formation of a hairpin which frees
Bacterial_small_RNA
peptidase, leader peptide hydrolase, leader proteinase, signal peptidase, pilin leader peptidase, SPC, prokaryotic signal peptidase, prokaryotic leader peptidase
Signal_peptidase_I
Protein found in humans
transmembrane domain and a 43 amino acid C terminal cytoplasmic region. The leader sequence and 5'-untranslated region are contained in one exon. The large extracellular
Complement_receptor_1
FBI Ten Most Wanted List
individuals by the sequence number in which each individual has appeared on the list. Some individuals have even appeared twice, and often a sequence number was
FBI Ten Most Wanted Fugitives, 2020s
FBI_Ten_Most_Wanted_Fugitives,_2020s
Model of group development
Nurse Leader". Nursing Forum. 52 (1): 21–29. doi:10.1111/nuf.12161. ISSN 1744-6198. PMID 27194144. Tuckman, Bruce (1965). "Developmental sequence in small
Tuckman's stages of group development
Tuckman's_stages_of_group_development
Protein-coding gene in the species Homo sapiens
structure has been found to contain a 21-residue mitochondrial targeting leader sequence. The PAM16 gene encodes for a mitochondrial protein with multiple functions
PAM16
RNA family
plasmid inherit the FlmB gene, coding for FlmB RNA which binds the leader sequence of FlmA mRNA and represses its translation. Toxin-antitoxin system
FlmA-FlmB toxin-antitoxin system
FlmA-FlmB_toxin-antitoxin_system
Species of virus
consists of its 5' leader sequence. The PRRSV generates a 3' coterminal set of sgmRNAs. It has been shown that mutations within the leader transcription regulating
Porcine reproductive and respiratory syndrome virus 2
Porcine_reproductive_and_respiratory_syndrome_virus_2
Protein family
primary structure of these proteins contains an N-terminal hydrophobic leader sequence of 30-40 amino acids, which could represent a signal for translocation
Auxin_binding_protein
Protein
1994). "La autoantigen alleviates translational repression by the 5' leader sequence of the human immunodeficiency virus type 1 mRNA". Journal of Virology
Sjögren_syndrome_antigen_B
American biochemist
chaperone and not just directed to cross membranes by its terminal leader sequence. In 1997, she was elected to the National Academy of Sciences of the
Linda_Randall
Protein-coding gene in the species Homo sapiens
50kDa size and 418 amino acids in length. The N-terminus contains a leader sequence responsible for protein secretion out of the cell at residues 1-19
PEDF
Cytokine with structural similarity to Interleukin-2
untranslated region, (2) an unusually long N-terminal hydrophobic (leader) sequence, and (3) a dependency on the formation of what might be considered
Interleukin_15
she was played by Marjean Holden in a minor role with her only action sequence being a brief scuffle with Motaro, though the film acknowledges her then-current
Characters of the Mortal Kombat series
Characters_of_the_Mortal_Kombat_series
Fourth season of animated television series Invincible
Lee Pace, the latter of whom debuts as the voice of Grand Regent Thragg, leader of the Empire and the series' overall main antagonist. The season consists
Invincible_season_4
Marvel Studios film
death in Avengers: Endgame (2019). Shortland put an emphasis on the fight sequences and said this was the most violent MCU film so far. Filming took place
Black_Widow_(2021_film)
Dictator of Germany from 1933 to 1945
the Nazi era from 1933 until his suicide in 1945. He rose to power as the leader of the Nazi Party, becoming the chancellor of Germany in 1933 and then taking
Adolf_Hitler
LEADER SEQUENCE
LEADER SEQUENCE
Surname or Lastname
English
English : patronymic from Leader.Probably an Americanized spelling of German Lüders (see Lueders).
Boy/Male
American, British, Danish, Dutch, English, Finnish, French, German, Greek, Hindu, Indian, Latin, Swedish
Brave as a Lion; Strong Like a Lion; Lion Man; Man Like a Man
Surname or Lastname
English
English : occupational name for someone who thatched cottages with reeds, from an agent derivative of Middle English rēd(en) ‘to cover with reeds’.Americanized spelling of German Rieder.
Surname or Lastname
English
English : variant spelling of Lever.
Surname or Lastname
English
English : occupational name for someone who led a horse and cart conveying commodities from one place to another, Middle English ledere, an agent noun from Old English lǣdan ‘to lead’. The word may also sometimes have been used to denote a foreman or someone who led sport or dance, but the name certainly did not originate with leader in the modern sense ‘civil or military commander’; this is a comparatively recent development.English : occupational name for a worker in lead, from an agent derivative of Old English lēad ‘lead’.
Boy/Male
Indian, Sanskrit
Torch Bearer; Leader; Elder Brother
Surname or Lastname
English
English : variant of or patronymic from Meader.
Surname or Lastname
English
English : topographic name for someone who lived by a meadow, from Mead 1 + the suffix -er, denoting an inhabitant.English : occupational name for a brewer or seller of mead, Middle English med(i)er (see Mead 2).
Boy/Male
Latin American English Greek
Lion.
Surname or Lastname
English
English : occupational name for a farm laborer, from Middle English sedere ‘sower’ (agent derivative of sed ‘seed’).
Surname or Lastname
English
English : from a Norman personal name, Leodegar, Old French Legier, of Germanic origin, composed of the elements liut ‘people’, ‘tribe’ + gÄr, gÄ“r ‘spear’. The name was borne by a 7th-century bishop of Autun, whose fame contributed to the popularity of the name in France. (In Germany the name was connected with a different saint, an 8th-century bishop of Münster.)English : variant of Letcher, in part a deliberate alteration to avoid the association with Middle English lecheor ‘lecher’.
Boy/Male
French, German, Greek
Lion-man; Form of Leander; Brave as a Lion
Surname or Lastname
English
English : variant spelling of Loder.
Boy/Male
French
Form of Leander. 'Lionlike man.
Surname or Lastname
English
English : variant of Meader.
Surname or Lastname
English and Scottish
English and Scottish : variant spelling of Leeper.
Surname or Lastname
English (Norfolk)
English (Norfolk) : variant spelling of Leader 1.
Surname or Lastname
English (chiefly Lancashire and Yorkshire)
English (chiefly Lancashire and Yorkshire) : metonymic occupational name for a leatherworker or seller of leather goods, from Middle English lether, Old English leþer ‘leather’.
Surname or Lastname
German
German : occupational name for a cooper, a short form of Fassbender.English : from an agent derivative of Old English bendan ‘to bend (the bow)’, hence probably a metonymic occupational name for an archer. Compare Benbow.Hungarian : from bender ‘curl’, hence a nickname for someone with curly hair.
Surname or Lastname
English, Dutch, and German
English, Dutch, and German : occupational name for a herdsman, someone who tended a herd of domestic animals, Middle English herder, Middle Dutch herder, harde(r), Middle High German herder.German : from the medieval German personal name Herdher, composed of the elements hart ‘strong’ + heri, hari ‘army’.South German : habitational name from either of two places called Herdern: near Freiburg and near Winterthal in Switzerland.
LEADER SEQUENCE
LEADER SEQUENCE
Boy/Male
Tamil
Bhalanetra | பாலநேதà¯à®°
One who has An eye in the forehead
Girl/Female
American, Australian, Gaelic, Irish
Old; Wise; River; Ancient; God's Gracious Gift; River of Wisdom
Girl/Female
British, English
Mercy
Boy/Male
British, English
Blend of Ray and Shawn
Biblical
brother of assistance
Girl/Female
Indian
Lord Brahma's Daughter Laxmi
Girl/Female
Welsh
Arrow.
Boy/Male
Sikh
Kindness, Favor
Girl/Female
British, English, Greek
A God
Girl/Female
Hindu, Indian
Sparkling of Eye
LEADER SEQUENCE
LEADER SEQUENCE
LEADER SEQUENCE
LEADER SEQUENCE
LEADER SEQUENCE
n.
The fur of the beaver.
a.
Formed into a head; as, a headed cabbage.
n.
One who leases or gleans.
a.
Having three leaves; three-leaved.
n.
One who heads a movement, a party, or a mob; head; chief; leader.
a.
Having (such) a leaf or (so many) leaves; -- used in composition; as, broad-leafed; four-leafed.
n.
A tree or plant yielding fruit; as, a good bearer.
a.
Like lead in color, etc. ; as, a leaden sky.
a.
Thick-headed; stupid.
a.
Double-headed.
n.
One who deals; one who has to do, or has concern, with others; esp., a trader, a trafficker, a shopkeeper, a broker, or a merchant; as, a dealer in dry goods; a dealer in stocks; a retail dealer.
a.
Made of lead; of the nature of lead; as, a leaden ball.
n.
One who leaves, or withdraws.
n.
One who draws up or forms pleas; the draughtsman of pleas or pleadings in the widest sense; as, a special pleader.
a.
To make vapid or spiritless; as, to deaden wine.
a.
Furnished with a head (commonly as denoting intellectual faculties); -- used in composition; as, clear-headed, long-headed, thick-headed; a many-headed monster.
n.
A fall or plunge headforemost, as while riding a bicycle, or in bathing; as, to take a header.
a.
Fitted with lead; set in lead; as, leaded windows.
n.
A proof reader.
a.
Having two leaves; two-leaved.