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Chemical compound
Ionomycin is an ionophore and an antibiotic that binds calcium ions (Ca2+) in a ratio 1:1. It is produced by the bacterium Streptomyces conglobatus. It
Ionomycin
Chemical compound
identified as the major reactive oxygen species induced by TPA/PMA but not by ionomycin in mouse macrophages. Thus, TPA/PMA has been routinely used as an inducer
12-O-Tetradecanoylphorbol-13-acetate
12-O-Tetradecanoylphorbol-13-acetate
Chemical entity that reversibly binds ions
; Parker, William L.; Gougoutas, Jack Z. (1 June 1979). "Structure of ionomycin - a novel diacidic polyether antibiotic having high affinity for calcium
Ionophore
Membrane protein involved in transportation
Nonribosomally synthesized porters, such as: The Nigericin family The Ionomycin family 2.C: Ion-gradient-driven energizers 3.A: P-P-bond-hydrolysis-driven
Membrane_transport_protein
Family of enzymes
that can activate the classical PKCs. It is often used together with ionomycin which provides the calcium-dependent signals needed for activation of
Protein_kinase_C
Lack of response by the immune system to foreign substances
be used to study the anergy. The anergy in T cells can be induced by Ionomycin, the ionophore capable of raising intracellular concentration of calcium
Clonal_anergy
Human monocytic cell line
rhIL-4, rhGM-CSF, recombinant human tumour necrotic factor α (rhTNF-α) and Ionomycin. The HLA type for THP-1 is HLA-A*02:01; A*24:02; B*15:11; B*35:01; C*03:03;
THP-1_cell_line
membrane protein Integrase Integrin Intein Interferon Interleukin Inulin Ionomycin Ionone Iron–sulfur cluster Isoleucine Isomerase Isoprene K252a K252b KT5720
List_of_biomolecules
Chemical compound
tumor formation and to study mechanism of action. TPA, together with ionomycin, can also be used to stimulate T-cell activation, proliferation, and cytokine
Phorbol
Neurotoxin from the Indian Red Scorpion
inhibit [125I] apamin binding to synaptic membranes in the rat brain or ionomycin-induced 86Rb+ fluxes in C6 cells in vitro. This suggests that TmTx does
Tamulotoxin
Protein-coding gene in the species Homo sapiens
DNA-templated negative regulation of protein phosphorylation cellular response to ionomycin positive regulation of mRNA catabolic process cellular response to lipopolysaccharide
ZC3H12A
Israeli biotech company
Tacrolimus, Sirolimus, Ascomycin, Myriocin Ionophores: Valinomycin, Nonactin, Ionomycin Special antibiotics and molecular biology reagents. Anisomycin, Thiolutin
Fermentek
Protein-coding gene in the species Homo sapiens
1016/0888-7543(90)90027-R. PMID 2149559. Edgeworth J, Freemont P, Hogg N (1989). "Ionomycin-regulated phosphorylation of the myeloid calcium-binding protein p14"
S100A9
Protein found in humans
Assfalg-Machleidt I, Popp O, Bestvater F, Holloschi A, et al. (July 2002). "Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family
Bcl-2
Chemical compound
that had been stimulated with phorbol 12-myristate 13-acetate (PMA) and ionomycin in a daily dosage approach. Ong KC, Khoo HE (August 1997). "Biological
Myricetin
protein kinases in enhancing B cell responses to phorboldiesters and ionomycin", Cell. Immunol., 142 (2): 398–415, doi:10.1016/0008-8749(92)90300-e,
Crosstalk_(biology)
Classification of membrane proteins including ion channels
Antibiotic (MA) Family 2.B.5 The Macrocyclic Polyether (MP) Family 2.B.6 The Ionomycin Family 2.B.7 The Transmembrane α-helical Peptide Phospholipid Translocation
Transporter Classification Database
Transporter_Classification_Database
Chemical compound
DeHoff, Brad; Sakito, Yoji (1990-06-01). "The total synthesis of (+)-ionomycin". Journal of the American Chemical Society. 112 (13): 5276–5290. Bibcode:1990JAChS
MoOPH
Broad-spectrum calcium channel blocker
did not affect the release of glutamate evoked by a calcium ionophore (ionomycin). A polypeptide (Tx3-3) present in the PhTx3 fraction reproduced the effects
Phoneutria nigriventer toxin-3
Phoneutria_nigriventer_toxin-3
Protein-coding gene in the species Homo sapiens
1016/S0378-1119(00)00258-4. PMID 10974555. Dahlgren C, Karlsson A (2002). "Ionomycin-induced neutrophil NADPH oxidase activity is selectively inhibited by
NOX1
Human protein
cellular response to phorbol 13-acetate 12-myristate cellular response to ionomycin transcription initiation from RNA polymerase II promoter G1/S transition
Cyclin-dependent_kinase_4
investigational – inviable – iodine I 131 tositumomab – iododoxorubicin – ionomycin – IORT – Incontinentia pigmenti – IRB – irinotecan – irofulven – irradiated
Index_of_oncology_articles
C41H64O13 digitoxin 71-63-6 C41H67NO15 troleandomycin 2751-09-9 C41H70O9Ca ionomycin 56092-81-0 C41H72O2 cholesteryl myristate 1989-52-2 C41H74N7O17P3S phytanoyl-CoA
List of compounds with carbon numbers 40–49
List_of_compounds_with_carbon_numbers_40–49
Protein-coding gene in the species Homo sapiens
of pri-miRNA transcription by RNA polymerase II cellular response to ionomycin cytokine production long-term memory brain-derived neurotrophic factor
NFATC4
IL-10-competent cells can occur by stimulation of B cells using PMA and ionomycin. Within the spleen of C57B1/6 mice, B10 cells comprise 1-3% (and B10+B10pro
B10_cell
Protein-coding gene in the species Homo sapiens
negative regulation of lung goblet cell differentiation cellular response to ionomycin positive regulation of hydrogen peroxide-induced cell death positive regulation
FOXP1
Protein found in humans
Fritz H, Fuentes-Prior P, Spiess E, Salvesen GS, Machleidt W (Jul 2002). "Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family
Calpain-2_catalytic_subunit
acids, conjugated MeSH D10.251.355.350 – gefarnate MeSH D10.251.355.391 – ionomycin MeSH D10.251.355.411 – isoprostanes MeSH D10.251.355.411.500 – f2-isoprostanes
List_of_MeSH_codes_(D10)
IONOMYCIN
IONOMYCIN
IONOMYCIN
IONOMYCIN
Girl/Female
Assamese, Hindu, Indian, Kannada, Malayalam, Marathi, Telugu
Luster of Gold
Girl/Female
Gujarati, Hindu, Indian
Small
Girl/Female
Tamil
Peacock
Girl/Female
British, English
White Stream Flaxen
Girl/Female
Hindu, Indian
Butterfly
Boy/Male
Hindu, Indian
Lord Shiva
Boy/Male
Tamil
Cloud, Water, Traveller
Girl/Female
Hindu, Indian
Request
Boy/Male
Tamil
To make melodic sounds, Chanting
Girl/Female
Hindu
Silent
IONOMYCIN
IONOMYCIN
IONOMYCIN
IONOMYCIN
IONOMYCIN