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Type II cytokine receptor
Interferon-lambda receptor (IFNLR), formerly known as the interleukin-28 receptor (IL28R), is a type II cytokine receptor found largely in epithelial
Interferon-lambda_receptor
Protein-coding gene in the species Homo sapiens
receptor that consists of interleukin 10 receptor, beta (IL10RB) and interferon lambda receptor 1 (IFNLR1) to signal via the JAK-STAT anti-viral pathway. [provided
Interferon_lambda_3
Group of anti-viral cytokines
The type III interferon group is a group of anti-viral cytokines that in humans consists of a singular family, IFN-λ (lambda). Their function is similar
Interferon_type_III
Protein-coding gene in the species Homo sapiens
Interferon lambda receptor 1 is a subunit for the interferon lambda receptor encoded by the IFNLR1 gene. It was formerly known as interleukin 28 receptor
Interferon_lambda_receptor_1
Signaling proteins released by host cells in response to the presence of pathogens
induction of Th1 immune response. Interferon type III IFN type III signals through the interferon-lambda receptor (IFNLR) consisting of IL10R2 (also
Interferon
Protein-coding gene in the species Homo sapiens
Interferon lambda 4 (gene symbol: IFNL4) is one of the most recently discovered human genes and the newest addition to the interferon lambda protein family
Interferon_lambda_4
Protein-coding gene in the species Homo sapiens
two chains of a receptor for type I interferons, including interferon-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus
IFNAR1
Sendai virus, virus of rodents
Donnelly RP, Kotenko SV (August 2010). "Interferon-lambda: a new addition to an old family". Journal of Interferon & Cytokine Research. 30 (8): 555–64. doi:10
Murine_respirovirus
Pharmaceutical drug
shown that genetic polymorphisms near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in response to the
Peginterferon_alfa-2a
Pharmaceutical drug
shown that genetic polymorphisms near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in response to the
Peginterferon_alfa-2b
Protein-coding gene in the species Homo sapiens
transduction. This gene and three other interferon receptor genes, IFNAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small
Interleukin 10 receptor, beta subunit
Interleukin_10_receptor,_beta_subunit
Protein-coding gene in the species Homo sapiens
Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon
Interferon_alpha-1
Protein-coding gene in the species Homo sapiens
signaling pathways as type I interferons. IL-29 receptor signals through JAK-STAT pathways leading to activated expression of interferon-stimulated genes and
Interleukin_29
Protein-coding gene in Homo sapiens
SV, Flaño E, Schindler C, et al. (November 2010). "Lambda interferon is the predominant interferon induced by influenza A virus infection in vivo". Journal
STAT2
Anti-inflammatory cytokine
(Mda-7), IL-26 and interferons type-I (IFN-alpha, -beta, -epsilon, -kappa, -omega), type-II (IFN-gamma) and type-III (IFN-lambda, including IL-28A, IL-28B
Interleukin_10
Human infectious disease
are currently under development include pegylated interferon lambda (λ), which binds to receptors on the hepatocyte surface leading to an intracellular
Hepatitis_D
Artificial stimulation of the immune system to treat cancer
S2CID 223082. Lasfar A, Abushahba W, Balan M, Cohen-Solal KA (2011). "Interferon lambda: a new sword in cancer immunotherapy". Clinical & Developmental Immunology
Cancer_immunotherapy
Belgian molecular biologist and entrepreneur (1947–1992)
interactions between a prokaryote (Escherichia coli) and a virus (bacteriophage lambda). Lecocq identified new bacterial genes influencing the decision between
Jean-Pierre_Lecocq
Russian medical geneticist
Interferon Lambda 4 Is Associated with Reduced Proliferation and Increased Cell Death in Human Hepatic Cells” published in the Journal of Interferon &
Ludmila_Prokunina-Olsson
RNA family
cell, HepG2 cells expressing miR-122) mount an effective antiviral interferon-lambda (IFNλ) based innate immune response to hepatitis C virus (HCV) infection
MiR-122
440.890 – interferon type i MeSH D12.776.467.374.440.890.125 – interferon type i, recombinant MeSH D12.776.467.374.440.890.125.100 – interferon alfa-2a
List_of_MeSH_codes_(D12.776)
Interleukin-10 receptor subunit alpha precursor - Homo sapiens (Human)". www.uniprot.org. Retrieved 2015-10-13. "IL10RB - Interleukin-10 receptor subunit beta
List of human clusters of differentiation
List_of_human_clusters_of_differentiation
Contagious disease caused by SARS-CoV-2
IM, Miao VN, Tzouanas CN, et al. (28 May 2020). "SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected
COVID-19
Protein that regulates the rate of DNA transcription
Tryptophan clusters 3.5.1 Family: Myb 3.5.2 Family: Ets-type 3.5.3 Family: Interferon regulatory factors 3.6 Class: TEA (transcriptional enhancer factor) domain
Transcription_factor
Study of genetic variants in different individuals
GWA study has shown that SNPs near the human IL28B gene, encoding interferon lambda 3, are associated with significant differences in response to the
Genome-wide_association_study
Group of disorders
vincristine, prednisone); with Rituximab, bortezomib, thalidomide, interferon-alpha, interferon-gamma, bexarotene, gemcitabine; and with hematopoietic stem cell
Epstein–Barr virus–associated lymphoproliferative diseases
Epstein–Barr_virus–associated_lymphoproliferative_diseases
Protein-coding gene in humans
Zernecke A, Bidzhekov K, et al. (March 2007). "Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells
CXCL7
Structural motif capable of binding DNA
several genes encoding transcription regulatory proteins from bacteriophage lambda and Escherichia coli: Cro, CAP, and λ repressor, which were found to share
Helix-turn-helix
Preventative and therapeutic medications for COVID-19 infection
categories, such as anti-inflammatory, antimalarial, interferon, protein-based, antibiotics, and receptor-modulating compounds. Pivotal Phase III trials assess
COVID-19_drug_development
Complete set of molecular interactions in a biological cell
of protein–protein interactions between viruses and the human type I interferon system network". Journal of Proteome Research. 9 (7): 3527–36. doi:10
Interactome
Protein-coding gene in the species Homo sapiens
EPRS, Glucocorticoid receptor, Glyceraldehyde 3-phosphate dehydrogenase, Host cell factor C1, Ku80, MNAT1 NPAT, Nuclear receptor co-repressor 2, POU2AF1
POU2F1
Organism altered by genetic engineering
hemophilia, human growth hormone to treat various forms of dwarfism, interferon to treat some cancers, erythropoietin for anemic patients, and tissue
Genetically_modified_organism
DNA pattern affecting anatomy development
and structural similarity to prokaryotic transcription factors, such as lambda phage proteins that alter the expression of genes in prokaryotes. The HTH
Homeobox
Variant of SARS-CoV-2, the virus that causes COVID-19
complex I (MHC-I) degradation", and that "SARS-CoV-2 ORF8 suppresses type I interferon (IFN)–mediated antiviral response". Referring to amino-acid position 501
SARS-CoV-2_Alpha_variant
Protein family
homology, 3D structure of POUs is similar to 3D structure of bacteriophage lambda repressor and other members of HTH_3 family. Human genes encoding proteins
POU_domain
Overview of the events of 2023 in science
therapeutic candidates are reported: a phase 3 trialed pegylated interferon lambda against COVID-19 (and other viruses) (9 Feb), a monkey-tested potential
January–March_2023_in_science
Drug repurposing research related to COVID-19
activator receptor) of at least 6 ng per ml." Drugs with immune modulating effects that may prove useful in COVID-19 treatment include type I Interferons such
COVID-19 drug repurposing research
COVID-19_drug_repurposing_research
Variant of a biopharmaceutical
of approved recombinant drugs (e.g., insulin, human growth hormone, interferons, erythropoietin, monoclonal antibodies and more) any other biotech company
Biosimilar
Protein-coding gene in the species Homo sapiens
S2CID 18269284. Santi E, Capone S, Mennuni C, et al. (2000). "Bacteriophage lambda display of complex cDNA libraries: a new approach to functional genomics"
EMX1
Vaccine against COVID-19
of the N protein. A robust increase of T helper cells (CD4+) secreting interferon gamma was detected 14 days after both doses in response to stimulation
CoronaVac
INTERFERON LAMBDA-RECEPTOR
INTERFERON LAMBDA-RECEPTOR
Girl/Female
Muslim
Flame
Girl/Female
Muslim
Praiseworthy, Praiser of Allah
Female
Native American
Native American Indian name ALAMEDA means "grove of cottonwood."
Girl/Female
Indian
Soft to touch
Surname or Lastname
English
English : habitational name from Lambden in Berwickshire.
Boy/Male
Hindu
Lord Ganesh, The huge bellied Lord
Female
Greek
(Λαμία) Greek myth name of an evil spirit who abducts and devours children, LAMIA means "large shark." The name means "vampire" in Latin and "fiend" in Arabic.
Female
Italian
Italian form of English Amber, AMBRA means "amber."
Girl/Female
Muslim
Dark lipped
Girl/Female
Indian
Ambitious
Girl/Female
Muslim
Ambitious
Girl/Female
Indian
Dark lipped
Boy/Male
Indian
Jaws.
Female
Spanish
Feminine form of Spanish Amado, AMADA means "beloved."
Girl/Female
Muslim
Soft to touch
Surname or Lastname
English
English : from Middle English lamb, a nickname for a meek and inoffensive person, or a metonymic occupational name for a keeper of lambs. See also Lamm.English : from a short form of the personal name Lambert.Irish : reduced Anglicized form of Gaelic Ó Luain (see Lane 3). MacLysaght comments: ‘The form Lamb(e), which results from a more than usually absurd pseudo-translation (uan ‘lamb’), is now much more numerous than O’Loan itself.’Possibly also a translation of French agneau.
Girl/Female
Arabic, Indian, Muslim, Pashtun, Sanskrit
Flame; Large; Spacious; Tall; Another Name for Durga and Lakshmi
Surname or Lastname
English
English : from a pet form of Lamb 1 and 2.English : from an Old Norse personal name Lambi, from lamb ‘lamb’.
Girl/Female
Indian
Praiseworthy, Praiser of Allah
Girl/Female
Indian
Flame
INTERFERON LAMBDA-RECEPTOR
INTERFERON LAMBDA-RECEPTOR
Girl/Female
Latin
From Ardea.
Girl/Female
American, British, English, Gaelic, Irish
Variants of the Name Casey; Alert; Watchful
Girl/Female
Hindu
Royalty
Boy/Male
Australian, Finnish, German, Portuguese
Gift of God
Girl/Female
Indian
Wish, Desire, Purpose, Use
Girl/Female
Latin
From the Andes.
Boy/Male
Hindu, Indian
Lord Murugan
Girl/Female
Chinese, Czechoslovakian, French, German, Greek, Italian, Swedish
Pure; Torture
Female
Chinese
beautiful wind.
Boy/Male
Tamil
Siddhanth | ஸிதà¯à®¤à®¾à®‚த
Principle, Lord Krishna
INTERFERON LAMBDA-RECEPTOR
INTERFERON LAMBDA-RECEPTOR
INTERFERON LAMBDA-RECEPTOR
INTERFERON LAMBDA-RECEPTOR
INTERFERON LAMBDA-RECEPTOR
v. i.
To interfere, as a horse.
n.
The name of the Greek letter /, /, corresponding with the English letter L, l.
v. i.
To bring forth a lamb or lambs, as sheep.
n.
One of the contestants in interference before the Patent Office.
p. pr. & vb. n.
of Interfere
v. i.
To clash or interfere.
n.
Any person who is as innocent or gentle as a lamb.
imp. & p. p.
of Interfere
v. i.
To interfere; to intermeddle.
pl.
of Lamina
pl.
of Lamina
n.
One who interferes.
n.
A viola da gamba.
imp. & p. p.
of Lamb
n.
The act of improperly interfering.
v. t.
To interfere and cut off; to debar.
v. i.
To strike one foot against the opposite foot or ankle in using the legs; -- sometimes said of a human being, but usually of a horse; as, the horse interferes.
v. i.
To come in collision; to be in opposition; to clash; as, interfering claims, or commands.
n.
A bruise or abrasion produced on the foot or ankle of a horse that interferes. See Interfere, 3.
n.
The point of junction of the sagittal and lambdoid sutures of the skull.