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Search references for HCN4. Phrases containing HCN4
See searches and references containing HCN4!HCN4
Protein-coding gene in the species Homo sapiens
channel 4 is a protein that in humans is encoded by the HCN4 gene. There are four HCN channels. HCN4 is prominently expressed in the pace maker region of
HCN4
Intermembrane proteins
activation, faster activation kinetics, and a lower sensitivity to cAMP, while HCN4 channels are slowly gating and strongly sensitive to cAMP. HCN2 and HCN3
HCN_channel
Electric current in the heart
(hyperpolarization-activated cyclic nucleotide–gated channel), of which 4 isoforms (HCN1 to HCN4) are known. Based on their sequence, HCN channels are classified as members
Pacemaker_current
Heart medication
congestive heart failure with reduced ejection fraction. Ivabradine binds to HCN4 receptors (potassium/sodium hyperpolarization-activated cyclic nucleotide-gated
Ivabradine
Investigational PMS/PMDD drugs
Ivabradine – hyperpolarization-activated cyclic nucleotide-gated channel HCN4 blocker Non-selective adrenergic receptor agonists (e.g., intravenous norepinephrine)
List of investigational orthostatic intolerance drugs
List_of_investigational_orthostatic_intolerance_drugs
Electric current produced in living cells
Jean-François; Shi, Nian-Qing; McLaughlin, Kelly A; Levin, Michael (2017). "HCN4 ion channel function is required for early events that regulate anatomical
Developmental_bioelectricity
Protein-coding gene in the species Homo sapiens
encoded by the HCN2 gene. HCN2 has been shown to interact with HCN1 and HCN4. The function of the channel is not known although its activation by hyperpolarization
HCN2
Protein domain
transduction. CNBD1; CNGA1; CNGA2; CNGA3; CNGB1; CNGB3; HCN1; HCN2; HCN3; HCN4; KCNH1; KCNH2; KCNH3; KCNH4; KCNH5; KCNH6; KCNH7; KCNH8; PNPLA6; PNPLA7;
Cyclic nucleotide-binding domain
Cyclic_nucleotide-binding_domain
Medical condition
or inhaled nitric oxide (NO). The calcium sensitizer levosimendan and the HCN4 blocker ivabradine are under formal development for treatment of low cardiac
Low_cardiac_output_syndrome
HGNC:4845; O60741 6955 HCN2 HGNC:4846; Q9UL51 6956 HCN3 HGNC:19183; Q9P1Z3 6957 HCN4 HGNC:16882; Q9Y3Q4 6958 HCRT HGNC:4847; O43612 6959 HCRTR1 HGNC:4848; O43613
List of human protein-coding genes 4
List_of_human_protein-coding_genes_4
Family of ion channel proteins
SLC9A10; SLC9A11 CNGA1; CNGA2; CNGA3; CNGA4 CNGB1; CNGB3 HCN1; HCN2; HCN3; HCN4 ITPR1; ITPR2; ITPR3 HVCN1 TPTE, part of the larger Voltage sensitive phosphatase
Cation_channel_superfamily
Protein-coding gene in the species Homo sapiens
nM, which is comparable to the affinities reported for PKA (100 nM) and HCN4 (240 nM). One of the interacting proteins is the two-pore potassium (K2P)
POPDC2
RNA family
in the sinus node leads to downregulation of the pacemaker ion channel, HCN4, and thus downregulation of the corresponding ionic current, which causes
Mir-370 microRNA precursor family
Mir-370_microRNA_precursor_family
Index of articles on biophysics
Ground reaction force Gs alpha subunit Gunther O. Hofmann HCN1 HCN2 HCN3 HCN4 HCN channel HERG HTR3A HTR3B HTR3C HTR3D HTR3E HVCN1 Hal Anger Hans Frauenfelder
Index_of_biophysics_articles
613119; KCNE3 Brugada syndrome 7; 613120; SCN3B Brugada syndrome 8; 613123; HCN4 Brunner syndrome; 300615; MAOA Burkitt's lymphoma; 113970; MYC Buschke–Ollendorff
List_of_OMIM_disorder_codes
HCN4
HCN4
HCN4
HCN4
Boy/Male
Anglo, British, English
From the Broom Covered Meadow
Boy/Male
Muslim
God is my father
Girl/Female
British, English, Indian, Sanskrit
Reason; Cause
Boy/Male
Hindu
King of gods
Girl/Female
Tamil
Sangamithra | ஸஂகமிதà¯à®°
Socially friendly
Girl/Female
Tamil
A beginning of new work
Male
Scandinavian
Scandinavian form of Old Norse Einarr, EINAR means "lone warrior."
Girl/Female
Greek
Reap; from Therasia.
Girl/Female
Indian
Charming; Love
Boy/Male
Muslim
Glory of the faith
HCN4
HCN4
HCN4
HCN4
HCN4